William H. Gerwick
Active 1986–2025
- 179
- Papers
- 22,851
- Citations
- 91
- h-index
- 168
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Medicine34.3%
- Biochemistry, Genetics and Molecular Biology33.1%
- Agricultural and Biological Sciences6.8%
- Chemistry6.7%
- Energy5.2%
- Environmental Science4.2%
- Other9.7%
Topics
- Microbial Natural Products and Biosynthesis12.7%
- Marine Sponges and Natural Products6.3%
- Metabolomics and Mass Spectrometry Studies4.1%
- Genomics and Phylogenetic Studies3.9%
- Computational Drug Discovery Methods2.9%
- Algal biology and biofuel production2.9%
- Other67.2%
Coauthors
- Lena Gerwick27
- Pieter C. Dorrestein27
- Evgenia Glukhov18
- Jehad Almaliti17
- Anthony J. O’Donoghue16
- David H. Sherman16
- Niclas Engene13
- Kerry L. McPhail12
- Roger G. Linington12
- Raphael Reher11
- Brian L. Márquez10
- Kelsey L. Alexander9
- Paul D. Boudreau9
- Tara Byrum9
- Thomas F. Murray9
- Tiago Leão9
- C. Benjamin Naman8
- Hyun Woo Kim8
- Janet L. Smith8
- Nicole E. Avalon8
- Thomas L. Simmons8
- Vivian Hook8
- Daniel Petras7
- Eduardo Esquenazi7
All papers
- Artificial intelligence for natural product drug discovery
Authors: Michael W. Mullowney, Katherine Duncan, Somayah S. Elsayed, Neha Garg, Justin J. J. van der Hooft, Nathaniel I. Martin, David Meijer, Barbara R. Terlouw, Friederike Biermann, Kai Blin, Janani Durairaj, Marina Gorostiola González, Eric J. N. Helfrich, Florian Huber, Stefan Leopold‐Messer, Kohulan Rajan, Tristan de Rond, Jeffrey A. van Santen, Maria Sorokina, Marcy J. Balunas, Mehdi A. Beniddir, Doris A. van Bergeijk, Laura M. Carroll, Chase M. Clark, Djork-Arné Clevert, Chris A. Dejong, Chao Du, Scarlet Ferrinho, Francesca Grisoni, Albert Hofstetter, Willem Jespers, Olga V. Kalinina, Satria A. Kautsar, Hyun Woo Kim, Tiago Leão, Joleen Masschelein, Evan Rees, Raphael Reher, Daniel Reker, Philippe Schwaller, Marwin Segler, Michael A. Skinnider, Allison S. Walker, Egon Willighagen, Barbara Zdrazil, Nadine Ziemert, Rebecca J. M. Goss, Pierre Guyomard, Andrea Volkamer, William H. Gerwick, Hyun Uk Kim, Rolf Müller, Gilles P. van Wezel, Gerard J. P. van Westen, Anna K. H. Hirsch, Roger G. Linington, Serina L. Robinson, Marnix H. Medema - Nature Reviews Drug Discovery 2023 cited by 390
- Systematic classification of unknown metabolites using high-resolution fragmentation mass spectra
Authors: Kai Dührkop, Louis‐Félix Nothias, Markus Fleischauer, Raphael Reher, Marcus Ludwig, Martin Hoffmann, Daniel Petras, William H. Gerwick, Juho Rousu, Pieter C. Dorrestein, Sebastian Böcker - Nature Biotechnology 2020 cited by 822
- microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics data
Authors: Simone Zuffa, Robin Schmid, Anelize Bauermeister, Paulo Wender Portal Gomes, Andrés Mauricio Caraballo‐Rodríguez, Yasin El Abiead, Allegra T. Aron, Emily C. Gentry, Jasmine Zemlin, Michael J. Meehan, Nicole E. Avalon, Robert H. Cichewicz, Ekaterina Buzun, Marvic Carrillo Terrazas, Chia-Yun Hsu, Renee Oles, Adriana Vasquez Ayala, Jiaqi Zhao, Hiutung Chu, Mirte C. M. Kuijpers, Sara L. Jackrel, Fidele Tugizimana, Lerato Nephali, Ian A. Dubery, Ntakadzeni Edwin Madala, Eduarda Antunes Moreira, Letícia V. Costa‐Lotufo, Norberto Peporine Lopes, Paula Rezende‐Teixeira, Paula C. Jimenez, Bipin Rimal, Andrew D. Patterson, Matthew F. Traxler, Rita de Cássia Pessotti, Daniel Alvarado-Villalobos, Giselle Tamayo‐Castillo, Priscila Chaverrí, Efraín Escudero‐Leyva, Luis-Manuel Quirós-Guerrero, Alexandre Bory, Juliette Joubert, Adriano Rutz, Jean‐Luc Wolfender, Pierre‐Marie Allard, Andreas Sichert, Sammy Pontrelli, Benjamin Pullman, Nuno Bandeira, William H. Gerwick, Katia Gindro, Josep Massana‐Codina, Berenike Wagner, Karl Forchhammer, Daniel Petras, Nicole Aiosa, Neha Garg, Manuel Liebeke, Patric Bourceau, Kyo Bin Kang, Henna Gadhavi, Luiz Pedro S. de Carvalho, Mariana Silva dos Santos, Alicia Isabel Pérez‐Lorente, Carlos Molina‐Santiago, Diego Romero, Raimo Franke, Mark Brönstrup, Arturo Vera Ponce de León, Phillip B. Pope, Sabina Leanti La Rosa, Giorgia La Barbera, Henrik M. Roager, Martin Frederik Laursen, Fabian Hammerle, Bianka Siewert, Ursula Peintner, Cuauhtémoc Licona‐Cassani, Lorena Rodríguez-Orduña, Evelyn Rampler, Felina Hildebrand, Gunda Koellensperger, Harald Schoeny, Katharina Hohenwallner, Lisa Panzenboeck, Rachel Gregor, Ellis C. O’Neill, Eve Tallulah Roxborough, Jane Odoi, Nicole J. Bale, Su Ding, Jaap S. Sinninghe Damsté, Xue Li Guan, Jerry Cui, Kou‐San Ju, Denise Brentan Silva, Fernanda Motta Ribeiro Silva, Gilvan Ferreira da Silva, Héctor H. F. Koolen, Carlismari O. Grundmann, Jason A. Clement and 9 more - Nature Microbiology 2024 cited by 114
- Minimum Information about a Biosynthetic Gene cluster
Authors: Marnix H. Medema, Renzo Kottmann, Pelin Yilmaz, Matthew Cummings, John Biggins, Kai Blin, Irene de Bruijn, Yit‐Heng Chooi, Jan Claesen, Roger Coates, Pablo Cruz‐Morales, Srikanth Duddela, Stephanie Düsterhus, Daniel Edwards, David P. Fewer, Neha Garg, Christoph Geiger, Juan Pablo Gomez‐Escribano, Anja Greule, Michalis Hadjithomas, Anthony S. Haines, Eric J. N. Helfrich, Matthew L. Hillwig, Keishi Ishida, Adam C. Jones, Carla S. Jones, Katrin Jungmann, Carsten Kegler, Hyun Uk Kim, Peter Kötter, Daniel Krug, Joleen Masschelein, Alexey V. Melnik, Simone M. Mantovani, Emily A. Monroe, Marcus A. Moore, Nathan A. Moss, Hans‐Wilhelm Nützmann, Guohui Pan, Amrita Pati, Daniel Petras, F. Jerry Reen, Federico Rosconi, Zhe Rui, Zhenhua Tian, Nicholas J. Tobias, Yuta Tsunematsu, Philipp Wiemann, Elizabeth E. Wyckoff, Xiaohui Yan, Grace Yim, Fengan Yu, Yunchang Xie, Bertrand Aigle, Alexander K. Apel, Carl J. Balibar, Emily P. Balskus, Francisco Barona‐Gómez, Andreas Bechthold, Helge B. Bode, Rainer Borriss, Sean F. Brady, Axel A. Brakhage, Patrick Caffrey, Yi‐Qiang Cheng, Jon Clardy, Russell J. Cox, René De Mot, Stefano Donadio, Mohamed S. Donia, Wilfred A. van der Donk, Pieter C. Dorrestein, Seán Doyle, Arnold J. M. Driessen, Monika Ehling‐Schulz, Karl-Dieter Entian, Michael A. Fischbach, Lena Gerwick, William H. Gerwick, Harald Gross, Bertolt Gust, Christian Hertweck, Monica Höfte, Susan E. Jensen, Jianhua Ju, Leonard Katz, Leonard Kaysser, Jonathan L. Klassen, Nancy P. Keller, Ján Kormanec, Oscar P. Kuipers, Tomohisa Kuzuyama, Nikos C. Kyrpides, Hyung-Jin Kwon, Sylvie Lautru, Rob Lavigne, Chia Y. Lee, Linquan Bai, Xinyu Liu, Wen Liu and 54 more - Nature Chemical Biology 2015 cited by 908
- A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Products
Authors: Raphael Reher, Hyun Woo Kim, Chen Zhang, Huanru Henry Mao, Mingxun Wang, Louis‐Félix Nothias, Andrés Mauricio Caraballo‐Rodríguez, Evgenia Glukhov, Bahar Teke, Tiago Leão, Kelsey L. Alexander, Brendan M. Duggan, Ezra L. Van Everbroeck, Pieter C. Dorrestein, Garrison W. Cottrell, William H. Gerwick - Journal of the American Chemical Society 2020 cited by 214
- Molecular Networking as a Dereplication Strategy
Authors: Jane Y. Yang, Laura M. Sanchez, Christopher M. Rath, Xueting Liu, Paul D. Boudreau, Nicole Bruns, Evgenia Glukhov, Anne Wodtke, Rafael de Felício, Amanda M. Fenner, Weng Ruh Wong, Roger G. Linington, Lixin Zhang, Hosana Maria Debonsi, William H. Gerwick, Pieter C. Dorrestein - Journal of Natural Products 2013 cited by 582
- Retrospective analysis of natural products provides insights for future discovery trends
Authors: Cameron R. Pye, Matthew J. Bertin, R. Scott Lokey, William H. Gerwick, Roger G. Linington - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 cited by 544
- DeepSAT: Learning Molecular Structures from Nuclear Magnetic Resonance Data
Authors: Hyun Woo Kim, Chen Zhang, Raphael Reher, Mingxun Wang, Kelsey L. Alexander, Louis-Félix Nothias, Yoo Kyong Han, Hyeji Shin, Ki Yong Lee, Kyu Hyeong Lee, Myeong Ji Kim, Pieter C. Dorrestein, William H. Gerwick, Garrison W. Cottrell - Journal of Cheminformatics, J. Cheminformatics 2023 cited by 60
- Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel
Authors: Anja Paatero, Juho Kellosalo, Bryan M. Dunyak, Jehad Almaliti, Jason E. Gestwicki, William H. Gerwick, Jack Taunton, Ville O. Paavilainen - Cell chemical biology 2016 cited by 131
- MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities
Authors: Liu Cao, Alexey Gurevich, Kelsey L. Alexander, C. Benjamin Naman, Tiago Leão, Evgenia Glukhov, Tal Luzzatto‐Knaan, Fernando Vargas, Robby Quinn, Amina Bouslimani, Louis‐Félix Nothias, Nitin K. Singh, Jon G. Sanders, Rodolfo Antonio Salido Benítez, Luke Thompson, Md-Nafiz Hamid, James T. Morton, Alla Mikheenko, Alexander Shlemov, Anton Korobeynikov, Iddo Friedberg, Rob Knight, Kasthuri Venkateswaran, William H. Gerwick, Lena Gerwick, Pieter C. Dorrestein, Pavel A. Pevzner, Hosein Mohimani - Cell Systems 2019 cited by 74
- Hippo pathway regulation by phosphatidylinositol transfer protein and phosphoinositides
Authors: Fulong Li, Vivian Fu, Guangbo Liu, Tracy Tang, Andrei W. Konradi, Xiao Peng, Esther K. Kemper, Benjamin F. Cravatt, James Franklin, ZhengMing Wu, Joshua E. Mayfield, Jack E. Dixon, William H. Gerwick, Kun‐Liang Guan - Nature Chemical Biology 2022 cited by 63
- SMART‐Miner: A convolutional neural network‐based metabolite identification from 1 H‐ 13 C HSQC spectra
Authors: Hyun Woo Kim, Chen Zhang, Garrison W. Cottrell, William H. Gerwick - Magnetic Resonance in Chemistry 2021 cited by 31
- Lessons from the Past and Charting the Future of Marine Natural Products Drug Discovery and Chemical Biology
Authors: William H. Gerwick, Bradley S. Moore - Chemistry & Biology 2012 cited by 589
- Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L
Authors: Anneliese S. Ashhurst, Arthur H. Tang, Pavla Fajtová, Michael C. Yoon, Anupriya Aggarwal, Max J. Bedding, Alexander Stoye, Laura Beretta, Dustin Pwee, Aleksandra Drelich, Danielle Skinner, Linfeng Li, Thomas D. Meek, James H. McKerrow, Vivian Hook, Chien‐Te K. Tseng, Mark Larance, Stuart Turville, William H. Gerwick, Anthony J. O’Donoghue, Richard J. Payne - Journal of Medicinal Chemistry 2021 cited by 84
- The Carmaphycins: New Proteasome Inhibitors Exhibiting an α,β‐Epoxyketone Warhead from a Marine Cyanobacterium
Authors: Albán R. Pereira, Andrew J. Kale, Andrew T. Fenley, Tara Byrum, Hosana Maria Debonsi, Michael K. Gilson, Frederick A. Valeriote, Bradley S. Moore, William H. Gerwick - ChemBioChem 2012 cited by 123
- Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity
Authors: Gregory LaMonte, Jehad Almaliti, Betsaida Bibo‐Verdugo, Lena Keller, Bing Zou, Jennifer H. Yang, Yevgeniya Antonova‐Koch, Pamela Orjuela-Sánchez, Colleen A. Boyle, Edgar Vigil, Lawrence Wang, Gregory M. Goldgof, Lena Gerwick, Anthony J. O’Donoghue, Elizabeth A. Winzeler, William H. Gerwick, Sabine Ottilie - Journal of Medicinal Chemistry 2017 cited by 98
- Commensal Oral Rothia mucilaginosa Produces Enterobactin, a Metal-Chelating Siderophore
Authors: Carla Uranga, Pablo Arroyo, Brendan M. Duggan, William H. Gerwick, Anna Edlund - mSystems 2020 cited by 71
- Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions
Authors: Michael C. Yoon, Angelo Solania, Zhenze Jiang, Mitchell P. Christy, Sonia Podvin, Charles Mosier, Christopher B. Lietz, Gen Ito, William H. Gerwick, Dennis W. Wolan, Gregory Hook, Anthony J. O’Donoghue, Vivian Hook - ACS Chemical Biology 2021 cited by 59
- Native metabolomics identifies the rivulariapeptolide family of protease inhibitors
Authors: Raphael Reher, Allegra T. Aron, Pavla Fajtová, Paolo Stincone, Berenike Wagner, Alicia Isabel Pérez‐Lorente, Chenxi Liu, Ido Ben‐Shalom, Wout Bittremieux, Mingxun Wang, Kyowon Jeong, Marie L. Matos‐Hernández, Kelsey L. Alexander, Eduardo J. E. Caro‐Diaz, C. Benjamin Naman, Julie Scanlan, Phil M. M. Hochban, Wibke E. Diederich, Carlos Molina‐Santiago, Diego Romero, Khaled A. Selim, Peter Saß, Heike Brötz‐Oesterhelt, Chambers C. Hughes, Pieter C. Dorrestein, Anthony J. O’Donoghue, William H. Gerwick, Daniel Petras - Nature Communications 2022 cited by 47
- A Universal Language for Finding Mass Spectrometry Data Patterns
Authors: Alan K. Jarmusch, Allegra T. Aron, Daniel Petras, Vanessa V. Phelan, Wout Bittremieux, Deepa Acharya, Mohammed M. A. Ahmed, Anelize Bauermeister, Matthew J. Bertin, Paul D. Boudreau, Ricardo M. Borges, Benjamin P. Bowen, Christopher J. Brown, Fernanda O. Chagas, Kenneth D. Clevenger, Mário S. P. Correia, William J. Crandall, Max Crüsemann, Tito Damiani, Oliver Fiehn, Neha Garg, William H. Gerwick, Jeffrey R. Gilbert, Daniel Globisch, Paulo Wender Portal Gomes, Steffen Heuckeroth, C. Andrew James, Scott A. Jarmusch, Sarvar A. Kakhkhorov, Kyo Bin Kang, Roland D. Kersten, Hyunwoo Kim, Riley D. Kirk, Oliver Kohlbacher, Eftychia Eva Kontou, Ken Liu, Itzel Lizama-Chamu, Gordon T. Luu, Tal Luzzatto‐Knaan, Michael T. Marty, Andrew C. McAvoy, Laura‐Isobel McCall, Osama G. Mohamed, Omri Nahor, Timo H. J. Niedermeyer, Trent R. Northen, Kirsten E. Overdahl, Tomáš Pluskal, Johannes Rainer, Raphael Reher, Elys P. Rodríguez, Timo Sachsenberg, Laura M. Sanchez, Robin Schmid, Cole Stevens, Zhenyu Tian, Ashootosh Tripathi, Hiroshi Tsugawa, Kozo Nishida, Yuki Matsuzawa, Justin J. J. van der Hooft, Andrea Vicini, Axel Walter, Tilmann Weber, Quanbo Xiong, Tao Xu, Haoqi Nina Zhao, Pieter C. Dorrestein, Mingxun Wang - 2022 cited by 45
- Enzymatic Halogenation of Terminal Alkynes
Authors: April L. Lukowski, Felix M. Hubert, Thuan-Ethan Ngo, Nicole E. Avalon, William H. Gerwick, Bradley S. Moore - Journal of the American Chemical Society 2023 cited by 33
- Leptochelins A–C, Cytotoxic Metallophores Produced by Geographically Dispersed Leptothoe Strains of Marine Cyanobacteria
Authors: Nicole E. Avalon, Mariana Reis, Christopher C. Thornburg, R. Thomas Williamson, Daniel Petras, Allegra T. Aron, George F. Neuhaus, Momen Al-Hindy, Jana Mitrevska, Leonor Ferreira, João Morais, Yasin El Abiead, Evgenia Glukhov, Kelsey L. Alexander, F. Alexandra Vulpanovici, Matthew J. Bertin, Syrena Whitner, Hyukjae Choi, Gabriella Spengler, Kirill A. Blinov, Ameen M. Almohammadi, Lamiaa A. Shaala, William Kew, Ljiljana Paša‐Tolić, Diaa T. A. Youssef, Pieter C. Dorrestein, Vı́tor Vasconcelos, Lena Gerwick, Kerry L. McPhail, William H. Gerwick - Journal of the American Chemical Society 2024 cited by 27
- Evaluation of bumetanide as a potential therapeutic agent for Alzheimer’s disease
Authors: Ben Boyarko, Sonia Podvin, Barry Greenberg, Jeremiah D. Momper, Yadong Huang, William H. Gerwick, Anne G. Bang, Luisa Quinti, Ana Griciuc, Doo Yeon Kim, Rudolph E. Tanzi, Howard Feldman, Vivian Hook - Frontiers in Pharmacology 2023 cited by 24
- On the Use of Neuro-2a Neuroblastoma Cells Versus Intact Neurons in Primary Culture for Neurotoxicity Studies
Authors: Keith T. LePage, Robert Dickey, William H. Gerwick, Edward L.E. Jester, Thomas F. Murray - Critical Reviews in Neurobiology 2005 cited by 158
