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Xin‐Yuan Guan

Active 1992–2025

Also published as
Xin-Yuan Guan
271
Papers
31,805
Citations
97
h-index
250
i10-index

Citations

Citations per year for Xin‐Yuan Guan1973: 1 citations1985: 1 citations1987: 2 citations1988: 1 citations1991: 1 citations1992: 3 citations1993: 11 citations1994: 63 citations1995: 72 citations1996: 90 citations1997: 77 citations1998: 120 citations1999: 148 citations2000: 138 citations2001: 152 citations2002: 159 citations2003: 113 citations2004: 117 citations2005: 107 citations2006: 117 citations2007: 111 citations2008: 168 citations2009: 159 citations2010: 178 citations2011: 177 citations2012: 244 citations2013: 281 citations2014: 227 citations2015: 255 citations2016: 193 citations2017: 227 citations2018: 211 citations2019: 752 citations2020: 1,051 citations2021: 1,164 citations2022: 975 citations2023: 930 citations2024: 1,416 citations2025: 1,023 citations2026: 21 citations1974–1984: no citations, so these years are not shown1986: no citations, so this year is not shown1989–1990: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorChina: 4,563 citing papers, 32.2% of this breakdownUnited States: 2,933 citing papers, 20.7% of this breakdownUnited Kingdom: 586 citing papers, 4.2% of this breakdownHong Kong: 455 citing papers, 3.2% of this breakdownGermany: 438 citing papers, 3.1% of this breakdownJapan: 410 citing papers, 2.9% of this breakdownItaly: 322 citing papers, 2.3% of this breakdownCanada: 296 citing papers, 2.1% of this breakdownFrance: 288 citing papers, 2% of this breakdownIndia: 272 citing papers, 1.9% of this breakdownSouth Korea: 256 citing papers, 1.8% of this breakdownAustralia: 243 citing papers, 1.7% of this breakdown
0%32.2%Other 21.9%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology55.3%
  • Medicine32.8%
  • Immunology and Microbiology5.1%
  • Neuroscience1.8%
  • Engineering1.4%
  • Agricultural and Biological Sciences0.8%
  • Other2.8%

Topics

  • Cancer-related molecular mechanisms research4.4%
  • MicroRNA in disease regulation4%
  • RNA modifications and cancer3.9%
  • Cancer Cells and Metastasis3.5%
  • Epigenetics and DNA Methylation3%
  • Circular RNAs in diseases3%
  • Other78.2%

Coauthors

All papers

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  1. Exploring treatment options in cancer: tumor treatment strategies

    Authors: Beilei Liu, Hongyu Zhou, Licheng Tan, Kin To Hugo Siu, Xin‐Yuan Guan - Signal Transduction and Targeted Therapy 2024 cited by 988

  2. N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis

    Authors: Rixin Chen, Xin Chen, Liangping Xia, Jiaxing Zhang, Zhizhong Pan, Xiaodan Ma, Kai Han, Jiewei Chen, Jean-Gabrie Judde, Olivier Déas, Feng Wang, Ning‐Fang Ma, Xin‐Yuan Guan, Jing‐Ping Yun, Feng‐Wei Wang, Rui‐Hua Xu, Dan Xie - Nature Communications 2019 cited by 838

  3. Cancer stem cells in hepatocellular carcinoma — from origin to clinical implications

    Authors: Terence K. Lee, Xin‐Yuan Guan, Stephanie Ma - Nature Reviews Gastroenterology & Hepatology 2021 cited by 479

  4. Targeting cancer-associated fibroblast-secreted WNT2 restores dendritic cell-mediated antitumour immunity

    Authors: Tuxiong Huang, Xiangyu Tan, Hui-Si Huang, Yuting Li, Beilei Liu, Kaisheng Liu, Xinchun Chen, Zhe Chen, Xin‐Yuan Guan, Chang Zou, Li Fu - Gut 2021 cited by 182

  5. Reshaping the systemic tumor immune environment (STIE) and tumor immune microenvironment (TIME) to enhance immunotherapy efficacy in solid tumors

    Authors: Liangliang Xu, Chang Zou, Shanshan Zhang, Timothy Shun Man Chu, Yan Zhang, Weiwei Chen, Cai‐Ning Zhao, Yang Li, Zhiyuan Xu, Shaowei Dong, Hao Yu, Bo Li, Xin‐Yuan Guan, Yuzhu Hou, Feng‐Ming Kong - Journal of Hematology & Oncology 2022 cited by 227

  6. Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma

    Authors: Oscar W.H. Yeung, Chung Mau Lo, Chang‐Chun Ling, Qi Xiang, Wei Geng, Chang Xian Li, TP Ng, Stuart J. Forbes, Xin‐Yuan Guan, Ronnie T.P. Poon, Sheung-Tat Fan, Kwan Man - Journal of Hepatology 2014 cited by 493

  7. Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma

    Authors: Lanqi Gong, Dora Lai‐Wan Kwong, Wei Dai, Pingan Wu, Shanshan Li, Qian Yan, Yu Zhang, Baifeng Zhang, Xiaona Fang, Li Liu, Min Luo, Beilei Liu, Larry Ka-Yue Chow, Qingyun Chen, Jinlin Huang, Victor Lee, Ka-On Lam, Anthony W.I. Lo, Zhiwei Chen, Yan Wang, Anne W.M. Lee, Xin‐Yuan Guan - Nature Communications 2021 cited by 212

  8. Nasopharyngeal carcinoma cells promote regulatory T cell development and suppressive activity via CD70-CD27 interaction

    Authors: Lanqi Gong, Jie Luo, Yu Zhang, Yuma Yang, Shanshan Li, Xiaona Fang, Baifeng Zhang, Jiao Huang, Larry Ka-Yue Chow, Dittman Lai‐Shun Chung, Jinlin Huang, Cuicui Huang, Qin Liu, Lu Bai, Yuen Chak Tiu, Pingan Wu, Yan Wang, George Sai‐Wah Tsao, Dora Lai‐Wan Kwong, Anne W.M. Lee, Wei Dai, Xin‐Yuan Guan - Nature Communications 2023 cited by 117

  9. Intrinsic RNA Targeting Triggers Indiscriminate DNase Activity of CRISPR‐Cas12a

    Authors: Jiongyu Zhang, Ziyue Li, Chong Guo, Xin‐Yuan Guan, Lori Avery, David Banach, Changchun Liu - Angewandte Chemie International Edition 2024 cited by 65

  10. Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

    Authors: Leilei Chen, Yan Li, Chi Ho Lin, Tim Hon Man Chan, Raymond Kwok Kei Chow, Yangyang Song, Ming Liu, Yun Yuan, Li Fu, Kar Lok Kong, Lihua Qi, Yan Li, Na Zhang, Amy H.Y. Tong, Dora L.�W. Kwong, Kwan Man, Chung Mau Lo, Si Lok, Daniel G. Tenen, Xin-Yuan Guan - Nature Medicine 2013 cited by 541

  11. 3D Biomimetic Models to Reconstitute Tumor Microenvironment In Vitro: Spheroids, Organoids, and Tumor‐on‐a‐Chip

    Authors: Wenxiu Li, Zhihang Zhou, Xiaoyu Zhou, Bee Luan Khoo, Renardi Gunawan, Y. Rebecca Chin, Liang Zhang, Changqing Yi, Xin‐Yuan Guan, Mengsu Yang - Advanced Healthcare Materials 2023 cited by 102

  12. TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines

    Authors: Yan‐Yi Jiang, Yuan Jiang, Chunquan Li, Ying Zhang, Pushkar Dakle, Harvinder Kaur, Jianwen Deng, Ruby Yu‐Tong Lin, Lin Han, Jian‐Jun Xie, Yiwu Yan, Ngan Doan, Yueyuan Zheng, Anand Mayakonda, Masaharu Hazawa, Liang Xu, Yanyu Li, Luay Aswad, Maya Jeitany, Deepika Kanojia, Xin‐Yuan Guan, Jonathan Said, Wei Yang, Melissa J. Fullwood, De‐Chen Lin, H. Phillip Koeffler - Gastroenterology 2020 cited by 187

  13. Medioresinol as a novel PGC-1α activator prevents pyroptosis of endothelial cells in ischemic stroke through PPARα-GOT1 axis

    Authors: Yunjie Wang, Xin‐Yuan Guan, Chenglong Gao, Wenchen Ruan, Shunyi Zhao, Guoyin Kai, Fei Li, Tao Pang - Pharmacological Research 2021 cited by 113

  14. FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint Blockade in Hepatocellular Carcinoma

    Authors: Jiao Huang, Wai Ying Tsang, Xiaona Fang, Yu Zhang, Jie Luo, Lanqi Gong, Baifeng Zhang, Ching Ngar Wong, Zhi-Hong Li, Beilei Liu, Jinlin Huang, Yu-Ma Yang, Shan Liu, Liu-Xian Ban, Yiu Hong Chan, Xin‐Yuan Guan - Cancer Research 2024 cited by 95

  15. Ferroptosis: Promising approach for cancer and cancer immunotherapy

    Authors: Shuyue Zheng, Xin‐Yuan Guan - Cancer Letters 2023 cited by 60

  16. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

    Authors: H.G. Stunnenberg, Sergio Abrignani, David J. Adams, Melanie de Almeida, Lucia Altucci, Viren Amin, Ido Amit, Stylianos E. Antonarakis, Samuel Aparício, Takahiro Arima, Laura Arrigoni, Rob J.W. Arts, Vahid Asnafi, Manel Esteller, Jae‐Bum Bae, Kevin Baßler, Stephan Beck, Benjamin E. Berkman, B Bernstein, Mikhail Bilenky, Adrian Bird, Christoph Bock, Bernhard O. Boehm, Guillaume Bourque, Charles E. Breeze, Benedikt Brors, David Bujold, Oliver S. Burren, Marion J.G. Bussemakers, Adam S. Butterworth, Elı́as Campo, Enrique Carrillo de Santa Pau, Lisa H. Chadwick, Kui Ming Chan, Wei Chen, Tom H. Cheung, Luca Chiapperino, Nak Hyen Choi, Ho‐Ryun Chung, Laura Clarke, Joseph M. Connors, Philippe Cronet, John Danesh, Manolis Dermitzakis, Gerard Drewes, Pawel Durek, Stephanie O. M. Dyke, Tomasz Dyląg, Connie J. Eaves, Peter Ebert, Roland Eils, Jürgen Eils, Catherine Ennis, Tariq Enver, Elise A. Feingold, Bärbel Felder, Anne C. Ferguson‐Smith, Jude Fitzgibbon, Paul Flicek, Roger Foo, Peter Fraser, Mattia Frontini, Eileen E. M. Furlong, Sitanshu Gakkhar, Nina Gasparoni, Gilles Gasparoni, Daniel H. Geschwind, Petar Glažar, Thomas Graf, Frank Grosveld, Xin‐Yuan Guan, Roderic Guigó, Marta Gut, Alf Hamann, Bok-Ghee Han, R. Alan Harris, Simon Heath, Kristian Helin, Jan G. Hengstler, Alireza Heravi‐Moussavi, Karl Herrup, Steven Hill, Jason A. Hilton, Benjamin C. Hitz, Bernhard Horsthemke, Ming Hu, Jooyeon Hwang, Nancy Y. Ip, Takashi Ito, Biola M. Javierre, Sasa Jenko, Thomas Jenuwein, Yann Joly, Steven J.M. Jones, Yae Kanai, Hee Gyung Kang, Aly Karsan, Alexandra K. Kiemer, Song Cheol Kim, Bong-Jo Kim and 130 more - Cell 2016 cited by 566

  17. Cytokine and Chemokine Signals of T-Cell Exclusion in Tumors

    Authors: Yu Zhang, Xin‐Yuan Guan, Peng Jiang - Frontiers in Immunology 2020 cited by 146

  18. A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis

    Authors: Tailin He, Jialin Shang, Chenglong Gao, Xin‐Yuan Guan, Ying‐Yi Chen, Liwen Zhu, Luyong Zhang, Cun‐Jin Zhang, Jian Zhang, Tao Pang - Acta Pharmaceutica Sinica B 2020 cited by 134

  19. FOXO1 promotes tumor progression by increased M2 macrophage infiltration in esophageal squamous cell carcinoma

    Authors: Ying Wang, Zhaojie Lyu, Yanru Qin, Xia Wang, Liang-Zhan Sun, Yu Zhang, Lanqi Gong, Shayi Wu, Shuo Han, Ying Tang, Yongxu Jia, Dora Lai‐Wan Kwong, Ngar‐Woon Kam, Xin‐Yuan Guan - Theranostics 2020 cited by 170

  20. Long non-coding RNA NEAT1 mediated RPRD1B stability facilitates fatty acid metabolism and lymph node metastasis via c-Jun/c-Fos/SREBP1 axis in gastric cancer

    Authors: Yongxu Jia, Qian Yan, Yinli Zheng, Lei Li, Baifeng Zhang, Zhiwei Chang, Zehua Wang, Hong Tang, Yanru Qin, Xin‐Yuan Guan - Journal of Experimental & Clinical Cancer Research 2022 cited by 107

  21. Microglial CMPK2 promotes neuroinflammation and brain injury after ischemic stroke

    Authors: Xin‐Yuan Guan, Sitong Zhu, Jinqian Song, Kui Liu, Mei Liu, Luyang Xie, Yifang Wang, Jin Wu, Xiaojun Xu, Tao Pang - Cell Reports Medicine 2024 cited by 93

  22. Laminin γ2–mediating T cell exclusion attenuates response to anti–PD-1 therapy

    Authors: Lei Li, Jia-Ru Wei, Jun Dong, Qingguang Lin, Hong Tang, Yongxu Jia, Wanlin Tan, Qingyun Chen, Tingting Zeng, Shan Xing, Yanru Qin, Ying‐Hui Zhu, Yan Li, Xin‐Yuan Guan - Science Advances 2021 cited by 82

  23. CircLONP2 enhances colorectal carcinoma invasion and metastasis through modulating the maturation and exosomal dissemination of microRNA-17

    Authors: Kai Han, Feng-Wei Wang, Chenhui Cao, Ling Han, Jie-Wei Chen, Ri-Xin Chen, Zi-Hao Feng, Jie Luo, Xiao-Han Jin, Jin‐Ling Duan, Shu-Man Li, Ning-Fang Ma, Jing‐Ping Yun, Xin‐Yuan Guan, Zhi-Zhong Pan, Ping Lan, Rui‐Hua Xu, Dan Xie - Molecular Cancer 2020 cited by 190

  24. Single‐Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Esophageal Squamous Cell Carcinoma

    Authors: Yongxu Jia, Baifeng Zhang, Chunyang Zhang, Dora Lai‐Wan Kwong, Zhiwei Chang, Shanshan Li, Zehua Wang, Huiqiong Han, Jing Li, Yali Zhong, Xin Sui, Li Fu, Xin‐Yuan Guan, Yanru Qin - Advanced Science 2023 cited by 87