Anthony Letai
1977–2025 年に発表
- 138
- 論文数
- 39,817
- 被引用数
- 85
- h 指数
- 138
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine44.5%
- Biochemistry, Genetics and Molecular Biology44.4%
- Immunology and Microbiology4.7%
- Computer Science1.5%
- Engineering1.1%
- Chemistry0.7%
- その他3.1%
トピック
- Acute Myeloid Leukemia Research5.4%
- Cell death mechanisms and regulation4.9%
- Protein Degradation and Inhibitors2.4%
- Cancer Genomics and Diagnostics2.4%
- Ubiquitin and proteasome pathways2.2%
- Histone Deacetylase Inhibitors Research2.1%
- その他80.6%
共著者
- Jeremy Ryan37
- Joan Montero18
- Richard M. Stone15
- Daniel J. DeAngelo11
- Marina Konopleva11
- Jing Deng10
- Kristopher A. Sarosiek10
- Matthew S. Davids10
- Patrick Bhola10
- Tríona Ní Chonghaile9
- Jacqueline S. Garcia8
- Shruti Bhatt8
- Courtney D. DiNardo7
- Hagop M. Kantarjian7
- Jalaja Potluri7
- Jennifer R. Brown7
- Amanda L. Christie6
- Jennifer L. Guerriero6
- Joel D. Leverson6
- Keith W. Pratz6
- Salma Parvin6
- Veerle W. Daniëls6
- Andrew H. Wei5
- Brenda Chyla5
全論文
- Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia
著者: Courtney D. DiNardo, Brian A. Jonas, Vinod Pullarkat, Michael J. Thirman, Jacqueline S. Garcia, Andrew H. Wei, Marina Konopleva, Hartmut Döhner, Anthony Letai, Pierre Fenaux, Elizabeth A. Koller, Violaine Havelange, Brian Leber, Jordi Esteve, Jianxiang Wang, Vlatko Pejša, Roman Hájek, Kimmo Porkka, Árpád Illés, David Lavie, Roberto M. Lemoli, Kazuhito Yamamoto, Sung‐Soo Yoon, Jun‐Ho Jang, Su‐Peng Yeh, Mehmet Turgut, Wan‐Jen Hong, Ying Zhou, Jalaja Potluri, Keith W. Pratz - New England Journal of Medicine 2020 被引用: 2,771
- Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins
著者: Rumani Singh, Anthony Letai, Kristopher A. Sarosiek - Nature Reviews Molecular Cell Biology 2019 被引用: 2,074
- The landscape of somatic copy-number alteration across human cancers
著者: Rameen Beroukhim, Craig H. Mermel, Dale Porter, Guo Wei, Soumya Raychaudhuri, Jerry Donovan, Jordi Barretina, Jesse S. Boehm, Jennifer Dobson, Mitsuyoshi Urashima, Kevin T. Mc Henry, Reid M. Pinchback, Azra H. Ligon, Yoon‐Jae Cho, Leila Haery, Heidi Greulich, Michael Reich, Wendy Winckler, Michael S. Lawrence, Barbara A. Weir, Kumiko Tanaka, Derek Y. Chiang, Adam J. Bass, Alice Loo, Carter Hoffman, John R. Prensner, Ted Liefeld, Qing Gao, Derek Yecies, Sabina Signoretti, Elizabeth A. Maher, Frederic J. Kaye, Hidefumi Sasaki, Joel E. Tepper, Jonathan A. Fletcher, Josep Tabernero, José Baselga, Ming‐Sound Tsao, Francesca Demichelis, Mark A. Rubin, Pasi A. Jänne, Mark J. Daly, Carmelo Nucera, Ross L. Levine, Benjamin L. Ebert, Stacey Gabriel, Anil K. Rustgi, Cristina R. Antonescu, Marc Ladanyi, Anthony Letai, Levi A. Garraway, Massimo Loda, David G. Beer, Lawrence D. True, Aikou Okamoto, Scott L. Pomeroy, Samuel Singer, Todd R. Golub, Eric S. Lander, Gad Getz, William R. Sellers, Matthew Meyerson - Nature 2010 被引用: 4,185
- Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia
著者: Courtney D. DiNardo, Keith W. Pratz, Vinod Pullarkat, Brian A. Jonas, Martha Arellano, Pamela S. Becker, Olga Frankfurt, Marina Konopleva, Andrew H. Wei, Hagop M. Kantarjian, Tu Xu, Wan‐Jen Hong, Brenda Chyla, Jalaja Potluri, Daniel A. Pollyea, Anthony Letai - Blood 2018 被引用: 1,852
- Efficacy and Biological Correlates of Response in a Phase II Study of Venetoclax Monotherapy in Patients with Acute Myelogenous Leukemia
著者: Marina Konopleva, Daniel A. Pollyea, Jalaja Potluri, Brenda Chyla, Leah J. Hogdal, Todd Busman, Evelyn McKeegan, Ahmed Hamed Salem, Ming Zhu, Justin L. Ricker, William Blum, Courtney D. DiNardo, Tapan M. Kadia, Martin Dunbar, Rachel Kirby, Nancy Falotico, Joel D. Leverson, Rod Humerickhouse, Mack Mabry, Richard M. Stone, Hagop M. Kantarjian, Anthony Letai - Cancer Discovery 2016 被引用: 1,056
- An inhibitor of Bcl-2 family proteins induces regression of solid tumours
著者: Tilman Oltersdorf, Steven W. Elmore, Alexander R. Shoemaker, Robert C. Armstrong, David J. Augeri, Barbara Belli, Milan Bruncko, Thomas L. Deckwerth, Jürgen Dinges, Philip J. Hajduk, Mary K. Joseph, Shinichi Kitada, Stanley J. Korsmeyer, Aaron Kunzer, Anthony Letai, Chi Li, Michael J. Mitten, David G. Nettesheim, Shi-Chung Ng, Paul Nimmer, Jacqueline M. O’Connor, Anatol Oleksijew, Andrew M. Petros, John C. Reed, Shen Wang, Stephen K. Tahir, Craig B. Thompson, Kevin J. Tomaselli, Baole Wang, Michael Wendt, Haichao Zhang, Stephen W. Fesik, Saul H. Rosenberg - Nature 2005 被引用: 3,410
- Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
著者: Rongqing Pan, Jeremy Ryan, Deng Pan, Kai W. Wucherpfennig, Anthony Letai - Cell 2022 被引用: 196
- Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies
著者: Romain Guièze, Vivian M. Liu, Daniel Rosebrock, Alexis A. Jourdain, María Hernández‐Sánchez, Aina Zurita Martinez, Jing Sun, Elisa ten Hacken, Kaitlyn Baranowski, Philip A. Thompson, Jin-Mi Heo, Zachary Cartun, Ozan Aygün, J. Bryan Iorgulescu, Wandi Zhang, Giulia Notarangelo, Dimitri Livitz, Shuqiang Li, Matthew S. Davids, Anat Biran, Stacey M. Fernandes, Jennifer R. Brown, Ana Lako, Zoe Ciantra, Matthew A. Lawlor, Derin B. Keskin, Namrata D. Udeshi, William G. Wierda, Kenneth J. Livak, Anthony Letai, Donna Neuberg, J. Wade Harper, Steven A. Carr, Federica Piccioni, Christopher J. Ott, Ignaty Leshchiner, Cory M. Johannessen, John G. Doench, Vamsi K. Mootha, Gad Getz, Catherine J. Wu - Cancer Cell 2019 被引用: 360
- Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia
著者: Rongqing Pan, Leah J. Hogdal, Juliana M. Benito, Donna Bucci, Lina Han, Gautam Borthakur, Jörge E. Cortes, Daniel J. DeAngelo, LaKeisha Debose, Hong Mu, Hartmut Döhner, Verena I. Gaidzik, Ilene Galinsky, Leonard S. Golfman, Torsten Haferlach, Karine G. Harutyunyan, Jianhua Hu, Joel D. Leverson, Guido Marcucci, Markus Müschen, Rachel Newman, Eugene Park, Peter P. Ruvolo, Vivian Ruvolo, Jeremy Ryan, Sonja Schindela, Patrick A. Zweidler‐McKay, Richard M. Stone, Hagop M. Kantarjian, Michael Andreeff, Marina Konopleva, Anthony Letai - Cancer Discovery 2013 被引用: 735
- Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages
著者: Jennifer L. Guerriero, Alaba Sotayo, Holly Ponichtera, Jessica A. Castrillon, Alexandra L. Pourzia, Sara Schad, Shawn F. Johnson, Ruben D. Carrasco, Suzan Lazo, Roderick T. Bronson, Scott Davis, Mercedes Lobera, Michael A. Nolan, Anthony Letai - Nature 2017 被引用: 551
- Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia
著者: Qi Zhang, Bridget Riley‐Gillis, Lina Han, Yannan Jia, Alessia Lodi, Haijiao Zhang, Saravanan Ganesan, Rongqing Pan, Sergej Konoplev, Shannon Sweeney, Jeremy Ryan, Yulia Jitkova, Kenneth Dunner, Shaun Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen E. Kurtz, Vivian Ruvolo, Helen Ma, Connie C. Weng, Cassandra L. Ramage, Natalia Baran, Ce Shi, Tianyu Cai, R. Eric Davis, Venkata Lokesh Battula, Yingchang Mi, Jing Wang, Courtney D. DiNardo, Michael Andreeff, Jeffery W. Tyner, Aaron D. Schimmer, Anthony Letai, Rose Ann Padua, Carlos E. Bueso‐Ramos, Stefano Tiziani, Joel D. Leverson, Relja Popovic, Marina Konopleva - Signal Transduction and Targeted Therapy 2022 被引用: 181
- Safety and preliminary efficacy of venetoclax with decitabine or azacitidine in elderly patients with previously untreated acute myeloid leukaemia: a non-randomised, open-label, phase 1b study
著者: Courtney D. DiNardo, Keith W. Pratz, Anthony Letai, Brian A. Jonas, Andrew H. Wei, Michael J. Thirman, Martha Arellano, Mark G. Frattini, Hagop M. Kantarjian, Relja Popovic, Brenda Chyla, Tu Xu, Martin Dunbar, Suresh Agarwal, Rod Humerickhouse, Mack Mabry, Jalaja Potluri, Marina Konopleva, Daniel A. Pollyea - The Lancet Oncology 2018 被引用: 712
- Functional precision oncology: Testing tumors with drugs to identify vulnerabilities and novel combinations
著者: Anthony Letai, Patrick Bhola, Alana L. Welm - Cancer Cell 2021 被引用: 280
- Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
著者: Shruti Bhatt, Marissa S. Pioso, Elyse A. Olesinski, Binyam Yilma, Jeremy Ryan, Thelma Mashaka, Leutz Buon, Sophia Adamia, Haoling Zhu, Yanan Kuang, Abhishek R. Mogili, Abner Louissaint, Stephan Bohl, Annette S. Kim, Anita K. Mehta, Sneha Sanghavi, Youzhen Wang, Erick J. Morris, Ensar Halilovic, Cloud P. Paweletz, David M. Weinstock, Jacqueline S. Garcia, Anthony Letai - Cancer Cell 2020 被引用: 174
- Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
著者: Michael Certo, Victoria Del Gaizo Moore, Mari Nishino, Guo Wei, Stanley J. Korsmeyer, Scott A. Armstrong, Anthony Letai - Cancer Cell 2006 被引用: 1,261
- Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis
著者: David Lagares, Alba Santos, Paula Grasberger, Fei Liu, Clemens K. Probst, Rod A. Rahimi, Norihiko Sakai, Tobias Kuehl, Jeremy Ryan, Patrick Bhola, Joan Montero, Mohit Kapoor, Murray Baron, Xaralabos Varelas, Daniel J. Tschumperlin, Anthony Letai, Andrew M. Tager - Science Translational Medicine 2017 被引用: 232
- Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
著者: Anthony Letai, Michael C. Bassik, Loren D. Walensky, Mia D. Sorcinelli, Solly Weiler, Stanley J. Korsmeyer - Cancer Cell 2002 被引用: 1,640
- Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy
著者: Tríona Ní Chonghaile, Kristopher A. Sarosiek, Thanh-Trang T. Vo, Jeremy Ryan, Anupama Tammareddi, Victoria Del Gaizo Moore, Jing Deng, Kenneth C. Anderson, Paul G. Richardson, Yu‐Tzu Tai, Constantine S. Mitsiades, Ursula A. Matulonis, Ronny Drapkin, Richard M. Stone, Daniel J. DeAngelo, David J. McConkey, Stephen E. Sallan, Lewis B. Silverman, Michelle S. Hirsch, Daniel R. Carrasco, Anthony Letai - Science 2011 被引用: 595
- Maturation Stage of T-cell Acute Lymphoblastic Leukemia Determines BCL-2 versus BCL-XL Dependence and Sensitivity to ABT-199
著者: Tríona Ní Chonghaile, Justine E. Roderick, Cian Glenfield, Jeremy Ryan, Stephen E. Sallan, Lewis B. Silverman, Mignon L. Loh, Stephen P. Hunger, Brent L. Wood, Daniel J. DeAngelo, Richard M. Stone, Marian H. Harris, Alejandro Gutiérrez, Michelle A. Kelliher, Anthony Letai - Cancer Discovery 2014 被引用: 274
- Precision medicine for cancer with next-generation functional diagnostics
著者: Adam A. Friedman, Anthony Letai, David E. Fisher, Keith T. Flaherty - Nature reviews. Cancer 2015 被引用: 587
- The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cells in patients via a TP53-independent mechanism
著者: Mary Ann Anderson, Jing Deng, John F. Seymour, Constantine S. Tam, Su Young Kim, Joshua Fein, Lijian Yu, Jennifer R. Brown, David Westerman, Éric Ghigo, Ian J. Majewski, David Segal, Sari L. Heitner Enschede, David C.S. Huang, Matthew S. Davids, Anthony Letai, Andrew W. Roberts - Blood 2016 被引用: 329
- Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment
著者: Catherine Gutierrez, Aziz Al’Khafaji, Eric Brenner, Kaitlyn E. Johnson, Satyen H. Gohil, Ziao Lin, Binyamin A. Knisbacher, R. Durrett, Shuqiang Li, Salma Parvin, Anat Biran, Wandi Zhang, Laura Z. Rassenti, Thomas J. Kipps, Kenneth J. Livak, Donna Neuberg, Anthony Letai, Gad Getz, Catherine J. Wu, Amy Brock - Nature Cancer 2021 被引用: 111
- PPM1D-truncating mutations confer resistance to chemotherapy and sensitivity to PPM1D inhibition in hematopoietic cells
著者: Josephine Kahn, Peter G. Miller, Alexander J. Silver, Rob S. Sellar, Shruti Bhatt, Christopher J. Gibson, Marie McConkey, Dylan Adams, Brenton G. Mar, Philipp Mertins, Shaunt Fereshetian, Karsten Krug, Haoling Zhu, Anthony Letai, Steven A. Carr, John G. Doench, Siddhartha Jaiswal, Benjamin L. Ebert - Blood 2018 被引用: 219
- Drug-Induced Death Signaling Strategy Rapidly Predicts Cancer Response to Chemotherapy
著者: Joan Montero, Kristopher A. Sarosiek, Joseph D. DeAngelo, Ophélia Maertens, Jeremy Ryan, Dalia Ercan, Huiying Piao, Neil S. Horowitz, Ross S. Berkowitz, Ursula A. Matulonis, Pasi A. Jänne, Philip C. Amrein, Karen Cichowski, Ronny Drapkin, Anthony Letai - Cell 2015 被引用: 377
