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John G. Doench

2003–2026 年に発表

162
論文数
44,042
被引用数
80
h 指数
149
i10 指数

被引用数

John G. Doench の年別被引用数1983 年: 被引用 2 件1992 年: 被引用 1 件1994 年: 被引用 1 件1998 年: 被引用 2 件2003 年: 被引用 25 件2004 年: 被引用 90 件2005 年: 被引用 117 件2006 年: 被引用 113 件2007 年: 被引用 140 件2008 年: 被引用 123 件2009 年: 被引用 111 件2010 年: 被引用 84 件2011 年: 被引用 83 件2012 年: 被引用 58 件2013 年: 被引用 43 件2014 年: 被引用 156 件2015 年: 被引用 269 件2016 年: 被引用 350 件2017 年: 被引用 479 件2018 年: 被引用 652 件2019 年: 被引用 1,695 件2020 年: 被引用 2,384 件2021 年: 被引用 2,659 件2022 年: 被引用 2,532 件2023 年: 被引用 2,298 件2024 年: 被引用 3,376 件2025 年: 被引用 1,838 件2026 年: 被引用 83 件1984〜1991 年は被引用が無いため表示していません1993 年は被引用が無いため表示していません1995〜1997 年は被引用が無いため表示していません1999〜2002 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 7,683 件、この内訳の 30.5%中国: 引用元論文 4,588 件、この内訳の 18.2%ドイツ: 引用元論文 1,396 件、この内訳の 5.5%イギリス: 引用元論文 1,309 件、この内訳の 5.2%カナダ: 引用元論文 768 件、この内訳の 3.1%フランス: 引用元論文 731 件、この内訳の 2.9%日本: 引用元論文 684 件、この内訳の 2.7%イタリア: 引用元論文 626 件、この内訳の 2.5%オーストラリア: 引用元論文 573 件、この内訳の 2.3%オランダ: 引用元論文 520 件、この内訳の 2.1%スイス: 引用元論文 515 件、この内訳の 2%スペイン: 引用元論文 483 件、この内訳の 1.9%
0%30.5%その他 21.1%

機関

分野

  • Biochemistry, Genetics and Molecular Biology56%
  • Medicine30.9%
  • Immunology and Microbiology5.5%
  • Computer Science3%
  • Agricultural and Biological Sciences1.2%
  • Neuroscience1.1%
  • その他2.3%

トピック

  • CRISPR and Genetic Engineering6.7%
  • Ferroptosis and cancer prognosis3.8%
  • RNA modifications and cancer3.5%
  • MicroRNA in disease regulation2.2%
  • Epigenetics and DNA Methylation2.2%
  • RNA and protein synthesis mechanisms2.1%
  • その他79.5%

共著者

全論文

検索で開く
  1. Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

    著者: John G. Doench, Nicolò Fusi, Meagan E. Sullender, Mudra Hegde, Emma W Vaimberg, Katherine Donovan, Ian C. P. Smith, Zuzana Tóthová, Craig B. Wilen, Robert C. Orchard, Herbert W. Virgin, Jennifer Listgarten, David E. Root - Nature Biotechnology 2016 被引用: 4,983

  2. Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

    著者: Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil Dhruv, Shubhroz Gill, Ossia M. Eichhoff, Brinton Seashore‐Ludlow, Samuel D. Kaffenberger, John K. Eaton, Kenichi Shimada, Andrew J. Aguirre, Srinivas R. Viswanathan, Shrikanta Chattopadhyay, Pablo Tamayo, Wan Seok Yang, Matthew G. Rees, Sixun Chen, Žarko Bošković, Sarah Javaid, Cherrie Huang, Xiaoyun Wu, Yuen‐Yi Tseng, Elisabeth Roider, Dong Gao, James M. Cleary, Brian M. Wolpin, Jill P. Mesirov, Daniel A. Haber, Jeffrey A. Engelman, Jesse S. Boehm, Joanne Kotz, Cindy Hon, Yu Chen, William C. Hahn, Mitchell P. Levesque, John G. Doench, Michael E. Berens, Alykhan F. Shamji, Paul A. Clemons, Brent R. Stockwell, Stuart L. Schreiber - Nature 2017 被引用: 2,059

  3. A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles

    著者: Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, D. D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie Donahue, Bina Julian, Mariya Khan, David Wadden, Ian C. P. Smith, Daniel D. Lam, Arthur Liberzon, Courtney Toder, Mukta Bagul, Marek Orzechowski, Oana M. Enache, Federica Piccioni, Sarah Johnson, Nicholas Lyons, Alice H. Berger, Alykhan F. Shamji, Angela N. Brooks, Anita Vrcic, Corey Flynn, Jacqueline Rosains, David Y. Takeda, Roger Hu, Desiree Davison, Justin Lamb, Kristin Ardlie, Larson Hogstrom, Peyton Greenside, Nathanael S. Gray, Paul A. Clemons, Serena J. Silver, Xiaoyun Wu, Wen‐Ning Zhao, Willis Read-Button, Xiaohua Wu, Stephen J. Haggarty, Lucienne Ronco, Jesse S. Boehm, Stuart L. Schreiber, John G. Doench, Joshua A. Bittker, David E. Root, Bang Wong, Todd R. Golub - Cell 2017 被引用: 3,788

  4. Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

    著者: Ophir Shalem, Neville E. Sanjana, Ella Hartenian, Xi Shi, David Scott, Tarjei S. Mikkelsen, Dirk Heckl, Benjamin L. Ebert, David E. Root, John G. Doench, Feng Zhang - Science 2013 被引用: 5,596

  5. A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

    著者: Yilong Zou, Michael J. Palte, Amy Deik, Haoxin Li, John K. Eaton, Wenyu Wang, Yuen‐Yi Tseng, Rebecca Deasy, Maria Kost‐Alimova, Vlado Dančík, Elizaveta S. Leshchiner, Vasanthi S. Viswanathan, Sabina Signoretti, Toni K. Choueiri, Jesse S. Boehm, Bridget K. Wagner, John G. Doench, Clary B. Clish, Paul A. Clemons, Stuart L. Schreiber - Nature Communications 2019 被引用: 865

  6. Cytochrome P450 oxidoreductase contributes tophospholipid peroxidation in ferroptosis

    著者: Yilong Zou, Haoxin Li, Emily Graham, Amy Deik, John K. Eaton, Wenyu Wang, Gerardo Sandoval-Gomez, Clary B. Clish, John G. Doench, Stuart L. Schreiber - Nature Chemical Biology 2020 被引用: 705

  7. Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities

    著者: Kendall R Sanson, Ruth E. Hanna, Mudra Hegde, Katherine Donovan, Christine Strand, Meagan E. Sullender, Emma W Vaimberg, Amy Goodale, David E. Root, Federica Piccioni, John G. Doench - Nature Communications 2018 被引用: 1,130

  8. Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

    著者: Steven M. Corsello, Rohith T. Nagari, Ryan D. Spangler, Jordan Rossen, Mustafa Kocak, Jordan Bryan, Ranad Humeidi, D. D. Peck, Xiaoyun Wu, Andrew Tang, Vickie M. Wang, Samantha Bender, Evan Lemire, Rajiv Narayan, Philip Montgomery, Uri Ben‐David, Colin W. Garvie, Yejia Chen, Matthew G. Rees, Nicholas Lyons, James M. McFarland, Bang Wong, Li Wang, Nancy Dumont, Patrick J. O’Hearn, Eric Stefan, John G. Doench, Caitlin Harrington, Heidi Greulich, Matthew Meyerson, Francisca Vázquez, Aravind Subramanian, Jennifer A. Roth, Joshua A. Bittker, Jesse S. Boehm, Christopher C. Mader, Aviad Tsherniak, Todd R. Golub - Nature Cancer 2020 被引用: 883

  9. In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

    著者: Robert T. Manguso, Hans W. Pope, Margaret D. Zimmer, Flavian D. Brown, Kathleen B. Yates, Brian C. Miller, Natalie B. Collins, Kevin Bi, Martin W. LaFleur, Vikram R. Juneja, Sarah A. Weiss, Jennifer A. Lo, David E. Fisher, Diana Miao, Eliezer M. Van Allen, David E. Root, Arlene H. Sharpe, John G. Doench, W. Nicholas Haining - Nature 2017 被引用: 1,172

  10. Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway

    著者: Charles L. Evavold, Iva Hafner‐Bratkovič, Pascal Devant, Jasmin M. D’Andrea, Elsy M. Ngwa, Elvira Boršić, John G. Doench, Martin W. LaFleur, Arlene H. Sharpe, Jay R. Thiagarajah, Jonathan C. Kagan - Cell 2021 被引用: 417

  11. A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

    著者: Deng Pan, Aya Kobayashi, Peng Jiang, Lucas Ferrari de Andrade, Rong En Tay, Adrienne Luoma, Daphne Tsoucas, Xintao Qiu, Klothilda Lim, Prakash K. Rao, Henry W. Long, Guo‐Cheng Yuan, John G. Doench, Myles Brown, X. Shirley Liu, Kai W. Wucherpfennig - Science 2018 被引用: 875

  12. Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity

    著者: Jonathan R. Brestoff, Craig B. Wilen, John R. Moley, Yongjia Li, Wei Zou, Nicole P. Malvin, Marina N. Rowen, Brian T. Saunders, Hongming Ma, Madison R. Mack, Barry L. Hykes, Dale R. Balce, Anthony Orvedahl, Jesse W. Williams, Nidhi Rohatgi, Xiaoyan Wang, Michael R. McAllaster, Scott A. Handley, Brian Kim, John G. Doench, Bernd H. Zinselmeyer, Michael Diamond, Herbert W. Virgin, Andrew E. Gelman, Steven L. Teitelbaum - Cell Metabolism 2020 被引用: 388

  13. Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation

    著者: John G. Doench, Ella Hartenian, Daniel B. Graham, Zuzana Tóthová, Mudra Hegde, Ian C. P. Smith, Meagan E. Sullender, Benjamin L. Ebert, Ramnik J. Xavier, David E. Root - Nature Biotechnology 2014 被引用: 1,722

  14. Mutational processes shape the landscape of TP53 mutations in human cancer

    著者: Andrew O. Giacomelli, Xiaoping Yang, Robert Lintner, James M. McFarland, Marc Duby, Jaegil Kim, Thomas P. Howard, David Y. Takeda, Seav Huong Ly, Eejung Kim, Hugh Gannon, Brian Hurhula, Ted Sharpe, Amy Goodale, Briana Fritchman, Scott Steelman, Francisca Vázquez, Aviad Tsherniak, Andrew J. Aguirre, John G. Doench, Federica Piccioni, Charles W.M. Roberts, Matthew Meyerson, Gad Getz, Cory M. Johannessen, David E. Root, William C. Hahn - Nature Genetics 2018 被引用: 598

  15. Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy

    著者: Jun Wei, Lingyun Long, Wenting Zheng, Yogesh Dhungana, Seon Ah Lim, Cliff Guy, Yanyan Wang, Yong‐Dong Wang, Chenxi Qian, Beisi Xu, Anil KC, Jordy Saravia, Hongling Huang, Jiyang Yu, John G. Doench, Terrence L. Geiger, Hongbo Chi - Nature 2019 被引用: 436

  16. Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity

    著者: Gabriel K. Griffin, Jingyi Wu, Arvin Iracheta‐Vellve, James C. Patti, Jeffrey Hsu, Thomas Davis, Deborah Dele‐Oni, Peter P. Du, Aya Halawi, Jeffrey J. Ishizuka, Sarah Kim, Susan Klaeger, Nelson H. Knudsen, Brian C. Miller, Tung H. Nguyen, Kira E. Olander, Malvina Papanastasiou, Suzanna Rachimi, Emily Robitschek, Emily M. Schneider, Mitchell D. Yeary, Margaret D. Zimmer, Jacob D. Jaffe, Steven A. Carr, John G. Doench, W. Nicholas Haining, Kathleen B. Yates, Robert T. Manguso, B Bernstein - Nature 2021 被引用: 362

  17. MEN1 mutations mediate clinical resistance to menin inhibition

    著者: Florian Perner, Eytan M. Stein, Daniela V. Wenge, Sukrit Singh, Jeonghyeon Kim, Athina Apazidis, Homa Rahnamoun, Disha Anand, Christian Marinaccio, Charlie Hatton, Yanhe Wen, Richard M. Stone, David Schaller, Shoron Mowla, Wenbin Xiao, Holly A. Gamlen, Aaron J. Stonestrom, Sonali Persaud, Elizabeth T. Ener, Jevon Cutler, John G. Doench, Gerard M. McGeehan, Andrea Volkamer, John D. Chodera, Radosław P. Nowak, Eric S. Fischer, Ross L. Levine, Scott A. Armstrong, Sheng F. Cai - Nature 2023 被引用: 243

  18. Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade

    著者: Jeffrey J. Ishizuka, Robert T. Manguso, Collins Cheruiyot, Kevin Bi, Arpit Panda, Arvin Iracheta‐Vellve, Brian C. Miller, Peter P. Du, Kathleen B. Yates, Juan Dubrot, Ilana Buchumenski, Dawn E. Comstock, Flavian D. Brown, Austin Ayer, Ian C. Kohnle, Hans W. Pope, Margaret D. Zimmer, Debattama R. Sen, Sarah Kate Lane-Reticker, Emily Robitschek, Gabriel K. Griffin, Natalie B. Collins, Adrienne H. Long, John G. Doench, David Kozono, Erez Y. Levanon, W. Nicholas Haining - Nature 2018 被引用: 728

  19. In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer

    著者: Juan Dubrot, Peter P. Du, Sarah Kate Lane-Reticker, Emily Kessler, Audrey J. Muscato, Arnav Mehta, Samuel S. Freeman, Peter M. Allen, Kira E. Olander, Kyle Ockerman, Clara Wolfe, Fabius Wiesmann, Nelson H. Knudsen, Hsiao‐Wei Tsao, Arvin Iracheta‐Vellve, Emily M. Schneider, Andrea N. Rivera-Rosario, Ian C. Kohnle, Hans W. Pope, Austin Ayer, Gargi Mishra, Margaret D. Zimmer, Sarah Kim, Animesh Mahapatra, Hakimeh Ebrahimi-Nik, Dennie T. Frederick, Genevieve M. Boland, W. Nicholas Haining, David E. Root, John G. Doench, Nir Hacohen, Kathleen B. Yates, Robert T. Manguso - Nature Immunology 2022 被引用: 222

  20. Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies

    著者: Romain Guièze, Vivian M. Liu, Daniel Rosebrock, Alexis A. Jourdain, María Hernández‐Sánchez, Aina Zurita Martinez, Jing Sun, Elisa ten Hacken, Kaitlyn Baranowski, Philip A. Thompson, Jin-Mi Heo, Zachary Cartun, Ozan Aygün, J. Bryan Iorgulescu, Wandi Zhang, Giulia Notarangelo, Dimitri Livitz, Shuqiang Li, Matthew S. Davids, Anat Biran, Stacey M. Fernandes, Jennifer R. Brown, Ana Lako, Zoe Ciantra, Matthew A. Lawlor, Derin B. Keskin, Namrata D. Udeshi, William G. Wierda, Kenneth J. Livak, Anthony Letai, Donna Neuberg, J. Wade Harper, Steven A. Carr, Federica Piccioni, Christopher J. Ott, Ignaty Leshchiner, Cory M. Johannessen, John G. Doench, Vamsi K. Mootha, Gad Getz, Catherine J. Wu - Cancer Cell 2019 被引用: 360

  21. Cas9 activates the p53 pathway and selects for p53-inactivating mutations

    著者: Oana M. Enache, Verónica Rendo, Mai Abdusamad, Daniel D. Lam, Desiree Davison, Sangita Pal, Naomi Currimjee, Julian M. Hess, Sasha Pantel, Anwesha Nag, Aaron R. Thorner, John G. Doench, Francisca Vázquez, Rameen Beroukhim, Todd R. Golub, Uri Ben‐David - Nature Genetics 2020 被引用: 286

  22. Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection

    著者: Jin Wei, Mia Madel Alfajaro, Peter C. DeWeirdt, Ruth E. Hanna, William J. Lu-Culligan, Wesley L. Cai, Madison S. Strine, Shang-Min Zhang, Vincent R. Graziano, Cameron O. Schmitz, Jennifer Chen, Madeleine C. Mankowski, Renata B. Filler, Neal G. Ravindra, Victor Gasque, Fernando J. de Miguel, Ajinkya Patil, Huacui Chen, Kasopefoluwa Y. Oguntuyo, Laura Abriola, Yulia V. Surovtseva, Robert C. Orchard, Benhur Lee, Brett D. Lindenbach, Katerina Politi, David van Dijk, Cigall Kadoch, Matthew D. Simon, Qin Yan, John G. Doench, Craig B. Wilen - Cell 2020 被引用: 587

  23. ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling

    著者: Matteo Gentili, Bingxu Liu, Malvina Papanastasiou, Deborah Dele‐Oni, Marc A. Schwartz, Rebecca J. Carlson, Aziz Al’Khafaji, Karsten Krug, Adam Brown, John G. Doench, Steven A. Carr, Nir Hacohen - Nature Communications 2023 被引用: 125

  24. Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs

    著者: Jennifer Listgarten, Michael M. Weinstein, Benjamin P. Kleinstiver, Alexander A. Sousa, J. Keith Joung, Jake Crawford, Kevin Gao, Luong Hoang, Melih Elibol, John G. Doench, Nicolò Fusi - Nature Biomedical Engineering 2018 被引用: 340