W. Nicholas Haining
1999–2024 年に発表
- 52
- 論文数
- 24,316
- 被引用数
- 45
- h 指数
- 49
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine45%
- Immunology and Microbiology30.3%
- Biochemistry, Genetics and Molecular Biology21.7%
- Neuroscience1.1%
- Engineering0.8%
- Agricultural and Biological Sciences0.3%
- その他0.8%
トピック
- Immune Cell Function and Interaction12.1%
- Cancer Immunotherapy and Biomarkers9.9%
- Immunotherapy and Immune Responses7.6%
- CAR-T cell therapy research6.7%
- T-cell and B-cell Immunology6.7%
- Immune cells in cancer3.1%
- その他53.9%
共著者
- Kathleen B. Yates18
- Arlene H. Sharpe13
- Debattama R. Sen12
- E. John Wherry12
- Kevin Bi10
- Martin W. LaFleur10
- Brian C. Miller8
- Flavian D. Brown8
- Jernej Godec8
- John G. Doench8
- Rafi Ahmed8
- Robert T. Manguso8
- Gordon J. Freeman7
- Margaret D. Zimmer7
- Sarah A. Weiss6
- Dawn E. Comstock5
- Georg M. Lauer5
- Hans W. Pope5
- Nir Yosef5
- R. Anthony Barnitz5
- Rose Al Abosy5
- Arvin Iracheta‐Vellve4
- David Wolski4
- Gabriel K. Griffin4
全論文
- Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
著者: Brian C. Miller, Debattama R. Sen, Rose Al Abosy, Kevin Bi, Yamini V. Virkud, Martin W. LaFleur, Kathleen B. Yates, Ana Lako, Kristen D. Felt, Girish S. Naik, Michael P. Manos, Evisa Gjini, Juhi R. Kuchroo, Jeffrey J. Ishizuka, Jenna L. Collier, Gabriel K. Griffin, Seth Maleri, Dawn E. Comstock, Sarah A. Weiss, Flavian D. Brown, Arpit Panda, Margaret D. Zimmer, Robert T. Manguso, F. Stephen Hodi, Scott J. Rodig, Arlene H. Sharpe, W. Nicholas Haining - Nature Immunology 2019 被引用: 2,072
- Defining ‘T cell exhaustion’
著者: Christian U. Blank, W. Nicholas Haining, Werner Held, Patrick G. Hogan, Axel Kallies, Enrico Lugli, Rachel C. Lynn, Mary Philip, Anjana Rao, Nicholas P. Restifo, Andrea Schietinger, Ton N. Schumacher, Pamela L. Schwartzberg, Arlene H. Sharpe, Daniel E. Speiser, E. John Wherry, Ben Youngblood, Dietmar Zehn - Nature reviews. Immunology 2019 被引用: 1,584
- Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
著者: Kristen E. Pauken, Morgan A. Sammons, Pamela M. Odorizzi, Sasikanth Manne, Jernej Godec, Omar Khan, Adam Drake, Zeyu Chen, Debattama R. Sen, Makoto Kurachi, R. Anthony Barnitz, Caroline Bartman, Bertram Bengsch, Alexander C. Huang, Jason M. Schenkel, Golnaz Vahedi, W. Nicholas Haining, Shelley L. Berger, E. John Wherry - Science 2016 被引用: 1,348
- Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection
著者: E. John Wherry, Sang‐Jun Ha, Susan M. Kaech, W. Nicholas Haining, Surojit Sarkar, Vandana Kalia, Shruti Subramaniam, Joseph N. Blattman, Daniel L. Barber, Rafi Ahmed - Immunity 2007 被引用: 2,130
- In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target
著者: Robert T. Manguso, Hans W. Pope, Margaret D. Zimmer, Flavian D. Brown, Kathleen B. Yates, Brian C. Miller, Natalie B. Collins, Kevin Bi, Martin W. LaFleur, Vikram R. Juneja, Sarah A. Weiss, Jennifer A. Lo, David E. Fisher, Diana Miao, Eliezer M. Van Allen, David E. Root, Arlene H. Sharpe, John G. Doench, W. Nicholas Haining - Nature 2017 被引用: 1,172
- The epigenetic landscape of T cell exhaustion
著者: Debattama R. Sen, James J. Kaminski, R. Anthony Barnitz, Makoto Kurachi, Ulrike Gerdemann, Kathleen B. Yates, Hsiao‐Wei Tsao, Jernej Godec, Martin W. LaFleur, Flavian D. Brown, Pierre Tonnerre, Raymond T. Chung, Damien C. Tully, Todd M. Allen, Nicole Frahm, Georg M. Lauer, E. John Wherry, Nir Yosef, W. Nicholas Haining - Science 2016 被引用: 990
- Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
著者: Shawn D. Blackburn, Haina Shin, W. Nicholas Haining, Tao Zou, Creg J. Workman, Antonio Polley, Michael R. Betts, Gordon J. Freeman, Dario A.A. Vignali, E. John Wherry - Nature Immunology 2008 被引用: 2,058
- Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity
著者: Gabriel K. Griffin, Jingyi Wu, Arvin Iracheta‐Vellve, James C. Patti, Jeffrey Hsu, Thomas Davis, Deborah Dele‐Oni, Peter P. Du, Aya Halawi, Jeffrey J. Ishizuka, Sarah Kim, Susan Klaeger, Nelson H. Knudsen, Brian C. Miller, Tung H. Nguyen, Kira E. Olander, Malvina Papanastasiou, Suzanna Rachimi, Emily Robitschek, Emily M. Schneider, Mitchell D. Yeary, Margaret D. Zimmer, Jacob D. Jaffe, Steven A. Carr, John G. Doench, W. Nicholas Haining, Kathleen B. Yates, Robert T. Manguso, B Bernstein - Nature 2021 被引用: 362
- CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
著者: Jiehui Deng, Eric S. Wang, Russell W. Jenkins, Shuai Li, Ruben Dries, Kathleen Yates, Sandeep Chhabra, Wei Huang, Hongye Liu, Amir Reza Aref, Elena V. Ivanova, Cloud P. Paweletz, Michaela Bowden, Chensheng W. Zhou, Grit S. Herter-Sprie, Jessica A. Sorrentino, John Bisi, Patrick H. Lizotte, Ashley A. Merlino, Max M. Quinn, Lauren E. Bufe, Annan Yang, Y. Zhang, Hua Zhang, Peng Gao, Ting Chen, Megan E. Cavanaugh, Amanda J. Rode, Eric Haines, Patrick J. Roberts, Jay C. Strum, William G. Richards, Jochen H. Lorch, Sareh Parangi, Viswanath Gunda, Genevieve M. Boland, Raphael Bueno, Sangeetha Palakurthi, Gordon J. Freeman, Jerome Ritz, W. Nicholas Haining, Norman E. Sharpless, Haribabu Arthanari, Geoffrey I. Shapiro, David A. Barbie, Nathanael S. Gray, Kwok‐Kin Wong - Cancer Discovery 2017 被引用: 781
- Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade
著者: Jeffrey J. Ishizuka, Robert T. Manguso, Collins Cheruiyot, Kevin Bi, Arpit Panda, Arvin Iracheta‐Vellve, Brian C. Miller, Peter P. Du, Kathleen B. Yates, Juan Dubrot, Ilana Buchumenski, Dawn E. Comstock, Flavian D. Brown, Austin Ayer, Ian C. Kohnle, Hans W. Pope, Margaret D. Zimmer, Debattama R. Sen, Sarah Kate Lane-Reticker, Emily Robitschek, Gabriel K. Griffin, Natalie B. Collins, Adrienne H. Long, John G. Doench, David Kozono, Erez Y. Levanon, W. Nicholas Haining - Nature 2018 被引用: 728
- PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity
著者: Vikram R. Juneja, Kathleen A. McGuire, Robert T. Manguso, Martin W. LaFleur, Natalie B. Collins, W. Nicholas Haining, Gordon J. Freeman, Arlene H. Sharpe - The Journal of Experimental Medicine 2017 被引用: 877
- Normalizing the environment recapitulates adult human immune traits in laboratory mice
著者: Lalit K. Beura, Sara E. Hamilton, Kevin Bi, Jason M. Schenkel, Oludare A. Odumade, Kerry A. Casey, Emily A. Thompson, Kathryn Fraser, Pamela C. Rosato, Ali Filali‐Mouhim, Rafick‐Pierre Sékaly, Marc K. Jenkins, Vaiva Vezys, W. Nicholas Haining, Stephen C. Jameson, David Masopust - Nature 2016 被引用: 1,096
- In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer
著者: Juan Dubrot, Peter P. Du, Sarah Kate Lane-Reticker, Emily Kessler, Audrey J. Muscato, Arnav Mehta, Samuel S. Freeman, Peter M. Allen, Kira E. Olander, Kyle Ockerman, Clara Wolfe, Fabius Wiesmann, Nelson H. Knudsen, Hsiao‐Wei Tsao, Arvin Iracheta‐Vellve, Emily M. Schneider, Andrea N. Rivera-Rosario, Ian C. Kohnle, Hans W. Pope, Austin Ayer, Gargi Mishra, Margaret D. Zimmer, Sarah Kim, Animesh Mahapatra, Hakimeh Ebrahimi-Nik, Dennie T. Frederick, Genevieve M. Boland, W. Nicholas Haining, David E. Root, John G. Doench, Nir Hacohen, Kathleen B. Yates, Robert T. Manguso - Nature Immunology 2022 被引用: 222
- Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans
著者: Kathleen B. Yates, Pierre Tonnerre, Geneviève Martin, Ulrike Gerdemann, Rose Al Abosy, Dawn E. Comstock, Sarah A. Weiss, David Wolski, Damien C. Tully, Raymond T. Chung, Todd M. Allen, Arthur Y. Kim, Sarah Fidler, Julie Fox, John Frater, Georg M. Lauer, W. Nicholas Haining, Debattama R. Sen - Nature Immunology 2021 被引用: 242
- PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity
著者: Martin W. LaFleur, Thao H. Nguyen, Matthew Coxe, Brian C. Miller, Kathleen B. Yates, Jacob E. Gillis, Debattama R. Sen, Emily F. Gaudiano, Rose Al Abosy, Gordon J. Freeman, W. Nicholas Haining, Arlene H. Sharpe - Nature Immunology 2019 被引用: 247
- Origin and differentiation of human memory CD8 T cells after vaccination
著者: Rama Akondy, Mark Fitch, Srilatha Edupuganti, Shu Yang, Haydn Kissick, Kelvin W. Li, Ben Youngblood, Hossam A. Abdelsamed, Donald J. McGuire, Kristen W. Cohen, Gabriela Alexe, Shashi Nagar, Megan McCausland, Gupta Sk, Pramila Tata, W. Nicholas Haining, M. Juliana McElrath, David Zhang, Bin Hu, William J. Greenleaf, Jörg J. Goronzy, Mark J. Mulligan, Marc K. Hellerstein, Rafi Ahmed - Nature 2017 被引用: 533
- CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
著者: Prakash Gupta, Jernej Godec, David Wolski, Emily Adland, Kathleen B. Yates, Kristen E. Pauken, Cormac Cosgrove, Carola Ledderose, Wolfgang G. Junger, Simon C. Robson, E. John Wherry, Galit Alter, Philip Goulder, Paul Klenerman, Arlene H. Sharpe, Georg M. Lauer, W. Nicholas Haining - PLoS Pathogens 2015 被引用: 390
- Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis
著者: Noa Novershtern, Aravind Subramanian, Lee N. Lawton, Raymond H. Mak, W. Nicholas Haining, Marie McConkey, Naomi Habib, Nir Yosef, Cindy Y. Chang, Tal Shay, Garrett M. Frampton, Adam Drake, Ilya Leskov, Björn Nilsson, Fred Preffer, David Dombkowski, John Evans, Ted Liefeld, John S. Smutko, Jianzhu Chen, Nir Friedman, Richard A. Young, Todd R. Golub, Aviv Regev, Benjamin L. Ebert - Cell 2011 被引用: 1,001
- The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells
著者: Makoto Kurachi, R. Anthony Barnitz, Nir Yosef, Pamela M. Odorizzi, Michael DiIorio, Madeleine E. Lemieux, Kathleen B. Yates, Jernej Godec, Martin G. Klatt, Aviv Regev, E. John Wherry, W. Nicholas Haining - Nature Immunology 2014 被引用: 393
- Stable inhibitory activity of regulatory T cells requires the transcription factor Helios
著者: Hye‐Jung Kim, R. Anthony Barnitz, Taras Kreslavsky, Flavian D. Brown, Howell Moffett, Madeleine E. Lemieux, Yasemin Kaygusuz, Torsten Meißner, Tobias A.W. Holderried, Susan Chan, Philippe Kastner, W. Nicholas Haining, Harvey Cantor - Science 2015 被引用: 428
- Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF
著者: Michael Quigley, Florencia Pereyra, Björn Nilsson, Filippos Porichis, Catia Fonseca, Quentin Eichbaum, Boris Jülg, Jonathan L. Jesneck, Kathleen Brosnahan, Sabrina Imam, Kate Russell, Ildikó Y. Tóth, Alicja Piechocka‐Trocha, Douglas V. Dolfi, Jill Angelosanto, Alison Crawford, Haina Shin, Douglas S. Kwon, Jennifer Zupkosky, Loise M. Francisco, Gordon J. Freeman, E. John Wherry, Daniel E. Kaufmann, Bruce D. Walker, Benjamin L. Ebert, W. Nicholas Haining - Nature Medicine 2010 被引用: 514
- Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
著者: Elena Battistello, Kimberlee A. Hixon, Dawn E. Comstock, Clayton K. Collings, Xufeng Chen, Javier Rodríguez Hernáez, Soobeom Lee, Kasey S. Cervantes, Madeline M. Hinkley, Konstantinos Ntatsoulis, Annamaria Cesarano, Kathryn Hockemeyer, W. Nicholas Haining, Matthew T. Witkowski, Jun Qi, Aristotelis Tsirigos, Fabiana Perna, Iannis Aifantis, Cigall Kadoch - Molecular Cell 2023 被引用: 72
- Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
著者: Surojit Sarkar, Vandana Kalia, W. Nicholas Haining, Bogumila T. Konieczny, Shruti Subramaniam, Rafi Ahmed - The Journal of Experimental Medicine 2008 被引用: 629
- PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment
著者: Natalie B. Collins, Rose Al Abosy, Brian C. Miller, Kevin Bi, Qihong Zhao, Michael Quigley, Jeffrey Ishizuka, Kathleen B. Yates, Hans W. Pope, Robert T Manguso, Yashaswi Shrestha, Marc H. Wadsworth, Tudor Hughes, Alex K. Shalek, Jesse S. Boehm, William C. Hahn, John G. Doench, W. Nicholas Haining - Journal for ImmunoTherapy of Cancer 2022 被引用: 122
