Anton Simeonov
2000–2025 年に発表
- 194
- 論文数
- 22,158
- 被引用数
- 86
- h 指数
- 187
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology39.7%
- Medicine26.3%
- Computer Science16.7%
- Immunology and Microbiology4.9%
- Chemistry3.1%
- Engineering2%
- その他7.3%
トピック
- Computational Drug Discovery Methods8%
- Epigenetics and DNA Methylation2.5%
- SARS-CoV-2 and COVID-19 Research2.2%
- Histone Deacetylase Inhibitors Research1.5%
- COVID-19 Clinical Research Studies1.5%
- Bioinformatics and Genomic Networks1.5%
- その他82.8%
共著者
- Ajit Jadhav74
- Ruili Huang45
- David J. Maloney39
- Ganesha Rai35
- Menghang Xia34
- Christopher P. Austin30
- Matthew D. Hall27
- Adam Yasgar24
- Alexey Zakharov24
- Min Shen23
- Wei Zheng23
- Sam Michael22
- Mark J. Henderson21
- Paul Shinn20
- James Inglese19
- Xin Hu19
- Richard T. Eastman17
- Srilatha Sakamuru17
- Carleen Klumpp‐Thomas15
- Douglas S. Auld14
- Dorjbal Dorjsuren13
- Miao Xu13
- Stephen C. Kales13
- Wenwei Huang13
全論文
- Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses
著者: Jesse M. Jaynes, Rushikesh Sable, Michael Ronzetti, Wendy Bautista, Zachary Knotts, Abisola Abisoye-Ogunniyan, Dandan Li, Raul Calvo, Myagmarjav Dashnyam, Anju Singh, Theresa M. Guerin, Jason White, Sarangan Ravichandran, Parimal Kumar, Keyur Talsania, Vicky Chen, Anghesom Ghebremedhin, Balasubramanyam Karanam, Ahmad Bin Salam, Ruksana Amin, Taivan Odzorig, Taylor Aiken, Victoria Nguyen, Yansong Bian, Jelani C. Zarif, Amber E. de Groot, Monika Mehta, Lixin Fan, Xin Hu, Anton Simeonov, Nathan Pate, Mones Abu‐Asab, Marc Ferrer, Noel Southall, Chan-Young Ock, Yongmei Zhao, Henry Lopez, Serguei Kozlov, Natalia de Val, Clayton Yates, Bolormaa Baljinnyam, Juan Marugán, Udo Rudloff - Science Translational Medicine 2020 被引用: 426
- The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology
著者: Ann M. Richard, Ruili Huang, Suramya Waidyanatha, Paul Shinn, Bradley J. Collins, Inthirany Thillainadarajah, Chris Grulke, Antony Williams, Ryan Lougee, Richard Judson, Keith A. Houck, Mahmoud Shobair, Chihae Yang, James F. Rathman, Adam Yasgar, Suzanne Fitzpatrick, Anton Simeonov, Russell S. Thomas, Kevin M. Crofton, Richard S. Paules, John R. Bucher, Christopher P. Austin, Robert J. Kavlock, Raymond R. Tice - Chemical Research in Toxicology 2020 被引用: 310
- Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19
著者: Richard T. Eastman, Jacob S. Roth, Kyle R. Brimacombe, Anton Simeonov, Min Shen, Samarjit Patnaik, Matthew D. Hall - ACS Central Science 2020 被引用: 975
- Tox21Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways as Mediated by Exposure to Environmental Chemicals and Drugs
著者: Ruili Huang, Menghang Xia, Ðắc-Trung Nguyễn, Tongan Zhao, Srilatha Sakamuru, Jinghua Zhao, Sampada A. Shahane, Anna Rossoshek, Anton Simeonov - Frontiers in Environmental Science 2016 被引用: 213
- The NCATS BioPlanet – An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics
著者: Ruili Huang, Ivan Grishagin, Yuhong Wang, Tongan Zhao, Jon Greene, John C. Obenauer, Deborah K. Ngan, Ðắc-Trung Nguyễn, Rajarshi Guha, Ajit Jadhav, Noel Southall, Anton Simeonov, Christopher P. Austin - Frontiers in Pharmacology 2019 被引用: 320
- KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
著者: Kunihiko Hinohara, Hua‐Jun Wu, Sébastien Vigneau, Thomas O. McDonald, Kyomi J. Igarashi, Kimiyo N. Yamamoto, Thomas Madsen, Anne Fassl, Shawn B. Egri, Malvina Papanastasiou, Lina Ding, Guillermo Peluffo, Ofir Cohen, Stephen C. Kales, Madhu Lal‐Nag, Ganesha Rai, David J. Maloney, Ajit Jadhav, Anton Simeonov, Nikhil Wagle, Myles Brown, Alexander Meissner, Piotr Siciński, Jacob D. Jaffe, Rinath Jeselsohn, Alexander A. Gimelbrant, Franziska Michor, Kornélia Polyák - Cancer Cell 2018 被引用: 254
- Unexplored therapeutic opportunities in the human genome
著者: Tudor I. Oprea, Cristian Bologa, Søren Brunak, Allen Campbell, Gregory N. Gan, Anna Gaulton, Shawn M. Gomez, Rajarshi Guha, Anne Hersey, Jayme Holmes, Ajit Jadhav, Lars Juhl Jensen, Gary L. Johnson, Anneli Karlson, Andrew R. Leach, Avi Ma’ayan, Anna Malovannaya, Subramani Mani, Stephen L. Mathias, Michael T. McManus, Terrence F. Meehan, Christian von Mering, Daniel Muthas, Ðắc-Trung Nguyễn, John P. Overington, George Papadatos, Jun Qin, Christian Reich, Bryan L. Roth, Stephan C. Schürer, Anton Simeonov, Larry A. Sklar, Noel Southall, Susumu Tomita, Ilinca Tudose, Oleg Ursu, D. Vidović, Anna Waller, David Westergaard, Jeremy J. Yang, Gergely Zahoránszky-Köhalmi - Nature Reviews Drug Discovery 2018 被引用: 385
- Pharos: Collating protein information to shed light on the druggable genome
著者: Dac-Trung Nguyen, Stephen L. Mathias, Cristian Bologa, Søren Brunak, Nicolas F. Fernandez, Anna Gaulton, Anne Hersey, Jayme Holmes, Lars Juhl Jensen, Anneli Karlsson, Guixia Liu, Avi Ma'ayan, Geetha Mandava, Subramani Mani, Saurabh Mehta, John P. Overington, Juhee Patel, Andrew D. Rouillard, Stephan C. Schürer, Timothy Sheils, Anton Simeonov, Larry A. Sklar, Noel Southall, Oleg Ursu, Dusica Vidovic, Anna Waller, Jeremy J. Yang, Ajit Jadhav, Tudor I. Oprea, Rajarshi Guha - Nucleic Acids Research, Nucleic Acids Res. 2016 被引用: 318
- Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy
著者: William C. Stafford, Xiaoxiao Peng, Maria Hägg Olofsson, Xiaonan Zhang, Diane K. Luci, Frank Leigh Lu, Qing Cheng, L. Tresaugues, Thomas S. Dexheimer, Nathan P. Coussens, Martin Augsten, Hanna-Stina Martinsson Ahlzén, Owe Orwar, Arne Östman, Sharon Stone‐Elander, David J. Maloney, Ajit Jadhav, Anton Simeonov, Stig Linder, Elias S.J. Arnér - Science Translational Medicine 2018 被引用: 243
- KDM5 histone demethylases repress immune response via suppression of STING
著者: Lizhen Wu, Jian Cao, Wesley L. Cai, Sabine M. Lang, J.R. Horton, Daniel J. Jansen, Zongzhi Liu, Jocelyn F. Chen, Meiling Zhang, Bryan T. Mott, Katherine Pohida, Ganesha Rai, Stephen C. Kales, Mark J. Henderson, Xin Hu, Ajit Jadhav, David J. Maloney, Anton Simeonov, Shu Zhu, Akiko Iwasaki, Matthew D. Hall, Xiaodong Cheng, Gerald S. Shadel, Qin Yan - PLoS Biology 2018 被引用: 166
- Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions
著者: Susanne A. I. Seidel, Patricia M. Dijkman, Wendy Lea, Geert van den Bogaart, Moran Jerabek‐Willemsen, Ana Lazic, Jeremiah S. Joseph, Prakash Srinivasan, Philipp Baaske, Anton Simeonov, Ilia Katritch, Fernando A. Melo, John E. Ladbury, Gideon Schreiber, Anthony Watts, Dieter Braun, Stefan Duhr - Methods 2012 被引用: 632
- Large-Scale Modeling of Multispecies Acute Toxicity End Points Using Consensus of Multitask Deep Learning Methods
著者: Sankalp Jain, Vishal B. Siramshetty, Vinicius M. Alves, Eugene N. Muratov, Nicole C. Kleinstreuer, Alexander Tropsha, Marc C. Nicklaus, Anton Simeonov, Alexey V. Zakharov - Journal of Chemical Information and Modeling, J. Chem. Inf. Model. 2021 被引用: 100
- CATMoS: Collaborative Acute Toxicity Modeling Suite
著者: Kamel Mansouri, Agnes L. Karmaus, Jeremy Fitzpatrick, Grace Patlewicz, Prachi Pradeep, Domenico Alberga, Nathalie Alépée, Timothy E. H. Allen, Dave Allen, Vinícius M. Alves, Carolina Horta Andrade, Tyler R. Auernhammer, Davide Ballabio, Shannon Bell, Emilio Benfenati, Sudin Bhattacharya, Joyce V. Bastos, Stephen A. Boyd, J.B. Brown, Stephen J. Capuzzi, Yaroslav Chushak, Heather L. Ciallella, Alex M. Clark, Viviana Consonni, Pankaj Daga, Sean Ekins, Sherif S. Farag, Maxim V. Fedorov, Denis Fourches, Domenico Gadaleta, Feng Gao, Jeffery M. Gearhart, Garett Goh, Jonathan M. Goodman, Francesca Grisoni, Chris Grulke, Thomas Härtung, Matthew Hirn, Pavel Karpov, Alexandru Korotcov, Giovanna J. Lavado, Michael S. Lawless, Xinhao Li, Thomas Luechtefeld, Filippo Lunghini, Giuseppe Felice Mangiatordi, Gilles Marcou, Dan H. Marsh, Todd M. Martin, Andrea Mauri, Eugene Muratov, Glenn J. Myatt, Ðắc-Trung Nguyễn, Orazio Nicolotti, Reine Note, Paritosh Pande, Amanda K. Parks, Tyler Peryea, Ahsan Habib Polash, Robert Ralló, Alessandra Roncaglioni, Craig Rowlands, Patricia Ruiz, Daniel P. Russo, Ahmed E Sayed, Risa Sayre, Timothy Sheils, Charles Siegel, Arthur C. Silva, Anton Simeonov, Sergey Sosnin, Noel Southall, Judy Strickland, Yun Tang, Brian J. Teppen, Igor V. Tetko, Dennis Thomas, Valery Tkachenko, Roberto Todeschini, Cosimo Toma, Ignacio J. Tripodi, Daniela Trisciuzzi, Alexander Tropsha, Alexandre Varnek, Kristijan Vuković, Zhongyu Wang, Liguo Wang, Katrina M. Waters, Andrew J. Wedlake, Sanjeeva J. Wijeyesakere, Dan Wilson, Zijun Xiao, Hongbin Yang, Gergely Zahoránszky-Köhalmi, Alexey Zakharov, Fagen F. Zhang, Zhen Zhang, Tongan Zhao, Hao Zhu, Kimberley M. Zorn ほか 2 名 - Environmental Health Perspectives 2021 被引用: 141
- Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries
著者: James Inglese, Douglas S. Auld, Ajit Jadhav, Ronald L. Johnson, Anton Simeonov, Adam Yasgar, Wei Zheng, Christopher P. Austin - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 被引用: 820
- Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
著者: Miao Xu, Emily M. Lee, Zhexing Wen, Yichen Cheng, Wei-Kai Huang, Xuyu Qian, Julia TCW, Jennifer Kouznetsova, Sarah C. Ogden, Christy Hammack, Fadi Jacob, Ha Nguyen, Misha Itkin, Catherine Hanna, Paul Shinn, Chase A. Allen, Sam Michael, Anton Simeonov, Wenwei Huang, Kimberly M. Christian, Alison Goate, Kristen Brennand, Ruili Huang, Menghang Xia, Guo‐li Ming, Wei Zheng, Hongjun Song, Hengli Tang - Nature Medicine 2016 被引用: 670
- TCRD and Pharos 2021: mining the human proteome for disease biology
著者: Timothy Sheils, Stephen L. Mathias, Keith J. Kelleher, Vishal B. Siramshetty, Dac-Trung Nguyen, Cristian Bologa, Lars Juhl Jensen, Dusica Vidovic, Amar Koleti, Stephan C. Schürer, Anna Waller, Jeremy J. Yang, Jayme Holmes, Giovanni Bocci, Noel Southall, Poorva Dharkar, Ewy A. Mathé, Anton Simeonov, Tudor I. Oprea - Nucleic Acids Research, Nucleic Acids Res. 2020 被引用: 176
- A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells
著者: Yu Chen, Carlos A. Tristan, Lu Chen, Vukasin M. Jovanovic, Claire Malley, Pei‐Hsuan Chu, Seungmi Ryu, Tao Deng, Pinar Ormanoglu, Dingyin Tao, Yuhong Fang, Jaroslav Slamecka, Hyenjong Hong, Christopher A. LeClair, Sam Michael, Christopher P. Austin, Anton Simeonov, Ilyas Singeç - Nature Methods 2021 被引用: 186
- Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy
著者: Nobu Oshima, Ryo Ishida, Shun Kishimoto, Kristin Beebe, Jeffrey Brender, Kazutoshi Yamamoto, Daniel J. Urban, Ganesha Rai, Michelle S. Johnson, Gloria A. Benavides, Giuseppe L. Squadrito, Dan Crooks, Joseph W. Jackson, Abhinav Joshi, Bryan T. Mott, Jonathan H. Shrimp, Michael A. Moses, Min-Jung Lee, Akira Yuno, Tobie D. Lee, Xin Hu, Tamara L. Anderson, Donna F. Kusewitt, Helen H. Hathaway, Ajit Jadhav, Didier Picard, Jane B. Trepel, James B. Mitchell, Gordon M. Stott, William Moore, Anton Simeonov, Larry A. Sklar, Jeffrey P. Norenberg, W. Marston Linehan, David J. Maloney, Chi V. Dang, Alex G. Waterson, Matthew D. Hall, Victor Darley‐Usmar, Murali C. Krishna, Leonard Μ. Neckers - Cell Reports 2020 被引用: 122
- A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth
著者: Lei Wang, Jianjun Chang, Diana Varghese, Michael T. Dellinger, Subodh Kumar, Anne M. Best, Julio C. Ruiz, Richard K. Bruick, Samuel Peña‐Llopis, Junjie Xu, David J. Babinski, Doug E. Frantz, Rolf A. Brekken, Amy Quinn, Anton Simeonov, Johnny Easmon, Elisabeth D. Martínez - Nature Communications 2013 被引用: 324
- Erratum: Unexplored therapeutic opportunities in the human genome
著者: Tudor I. Oprea, Cristian Bologa, Søren Brunak, Allen Campbell, Gregory N. Gan, Anna Gaulton, Shawn M. Gomez, Rajarshi Guha, Anne Hersey, Jayme Holmes, Ajit Jadhav, Lars Juhl Jensen, Gary L. Johnson, Anneli Karlson, Andrew R. Leach, Avi Ma’ayan, Anna Malovannaya, Subramani Mani, Steven L. Mathias, Michael T. McManus, Terrence F. Meehan, Christian von Mering, Daniel Muthas, Ðắc-Trung Nguyễn, John P. Overington, George Papadatos, Jun Qin, Christian Reich, Bryan L. Roth, Stephan C. Schürer, Anton Simeonov, Larry A. Sklar, Noel Southall, Susumu Tomita, Ilinca Tudose, Oleg Ursu, D. Vidović, Anna Waller, David Westergaard, Jeremy J. Yang, Gergely Zahoránszky-Köhalmi - Nature Reviews Drug Discovery 2018 被引用: 323
- A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses
著者: Liang Qin, Thomas S. Dexheimer, Ping Zhang, Andrew S. Rosenthal, Mark A. Villamil, Changjun You, Qiuting Zhang, Junjun Chen, Christine A. Ott, Hongmao Sun, Diane K. Luci, Bi‐Feng Yuan, Anton Simeonov, Ajit Jadhav, Hui Xiao, Yinsheng Wang, David J. Maloney, Zhihao Zhuang - Nature Chemical Biology 2014 被引用: 273
- Drug repurposing screens and synergistic drug‐combinations for infectious diseases
著者: Wei Zheng, Wei Sun, Anton Simeonov - British Journal of Pharmacology 2017 被引用: 264
- Fluorescence polarization assays in high-throughput screening and drug discovery: a review
著者: Matthew D. Hall, Adam Yasgar, Tyler Peryea, John Braisted, Ajit Jadhav, Anton Simeonov, Nathan P. Coussens - Methods and Applications in Fluorescence 2016 被引用: 219
- Gene expression analysis identifies global gene dosage sensitivity in cancer
著者: Rudolf S.N. Fehrmann, Juha Karjalainen, Małgorzata Krajewska, Harm-Jan Westra, David J. Maloney, Anton Simeonov, Tune H. Pers, Joel N. Hirschhorn, Ritsert C. Jansen, Erik Schultes, Herman H. H. B. M. van Haagen, Elisabeth G.E. de Vries, Gerard J. te Meerman, Cisca Wijmenga, Marcel A.T.M. van Vugt, Lude Franke - Nature Genetics 2015 被引用: 367
