Jane B. Trepel
1986–2024 年に発表
- 129
- 論文数
- 20,706
- 被引用数
- 89
- h 指数
- 128
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology54.8%
- Medicine34.8%
- Immunology and Microbiology4.3%
- Neuroscience1.4%
- Engineering0.9%
- Chemistry0.7%
- その他3.1%
トピック
- Heat shock proteins research5.3%
- Cancer, Hypoxia, and Metabolism3.9%
- Histone Deacetylase Inhibitors Research3%
- Epigenetics and DNA Methylation2.8%
- Cancer Immunotherapy and Biomarkers1.9%
- PARP inhibition in cancer therapy1.6%
- その他81.5%
共著者
- Min-Jung Lee48
- Sunmin Lee33
- Len Neckers32
- Seth M. Steinberg19
- William D. Figg16
- Akira Yuno14
- Kristin Beebe11
- Anish Thomas10
- Giuseppe Giaccone10
- Mehdi Mollapour10
- Wanping Xu10
- Yves Pommier10
- Shinji Tsutsumi9
- Yusuke Tomita9
- Edward A. Sausville8
- Eun Joo Chung8
- Jung Min Lee8
- Arun Rajan7
- Bradley T. Scroggins7
- Chrisostomos Prodromou7
- Cody J. Peer7
- James L. Gulley7
- Leonard Μ. Neckers7
- Yeong Sang Kim7
全論文
- Targeting the dynamic HSP90 complex in cancer
著者: Jane B. Trepel, Mehdi Mollapour, Giuseppe Giaccone, Len Neckers - Nature reviews. Cancer 2010 被引用: 1,528
- MGMT Status as a Clinical Biomarker in Glioblastoma
著者: Madison Butler, Lőrinc Sándor Pongor, Yuting Su, Liqiang Xi, Mark Raffeld, Martha Quezado, Jane B. Trepel, Kenneth Aldape, Yves Pommier, Jing Wu - Trends in cancer 2020 被引用: 346
- Structural and functional complexity of HSP90 in cellular homeostasis and disease
著者: Gabriela Chiosis, Chander Singh Digwal, Jane B. Trepel, Len Neckers - Nature Reviews Molecular Cell Biology 2023 被引用: 204
- Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer
著者: Nitin Roper, Moises J. Velez, Alberto Chiappori, Yoo Sun Kim, Jun S. Wei, Sivasish Sindiri, Nobuyuki Takahashi, Deborah Mulford, Suresh Kumar, Kris Ylaya, Christopher Trindade, Irena Manukyan, Anna‐Leigh Brown, Jane B. Trepel, Jung-Min Lee, Stephen M. Hewitt, Javed Khan, Anish Thomas - Nature Communications 2021 被引用: 163
- Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress
著者: Anish Thomas, Nobuyuki Takahashi, Vinodh N. Rajapakse, Xiaohu Zhang, Yilun Sun, Michele Ceribelli, Kelli M. Wilson, Yang Zhang, Erin Beck, Linda Sciuto, Samantha Nichols, Brian Elenbaas, Janusz Puc, Heike Dahmen, Astrid Zimmermann, Jillian Varonin, Christopher W. Schultz, Se Hyun Kim, Hirity Shimellis, Parth Desai, Carleen Klumpp‐Thomas, Lu Chen, Jameson Travers, Crystal McKnight, Sam Michael, Zina Itkin, Sunmin Lee, Akira Yuno, Min-Jung Lee, Christophe E. Redon, Jessica D. Kindrick, Cody J. Peer, Jun S. Wei, Mirit I. Aladjem, William D. Figg, Seth M. Steinberg, Jane B. Trepel, Frank T. Zenke, Yves Pommier, Javed Khan, Craig J. Thomas - Cancer Cell 2021 被引用: 177
- Entinostat plus Pembrolizumab in Patients with Metastatic NSCLC Previously Treated with Anti–PD-(L)1 Therapy
著者: Matthew D. Hellmann, Pasi A. Jänne, Mateusz Opyrchal, Navid Hafez, Luis E. Raez, Dmitry I. Gabrilovich, Fang Wang, Jane B. Trepel, Min-Jung Lee, Akira Yuno, Sunmin Lee, Susan Brouwer, Serap Sankoh, Lei Wang, David Tamang, Emmett V. Schmidt, Michael L. Meyers, Suresh S. Ramalingam, Elaine Shum, Peter Ordentlich - Clinical Cancer Research 2020 被引用: 124
- HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
著者: Jennifer S. Isaacs, Yun Jin Jung, David R. Mole, Sunmin Lee, Carlos A. Torres‐Cabala, Yuen‐Li Chung, Maria J. Merino, Jane B. Trepel, Berton Zbar, Jorge R. Toro, Peter J. Ratcliffe, W. Marston Linehan, Len Neckers - Cancer Cell 2005 被引用: 942
- An update on the status of HSP90 inhibitors in cancer clinical trials
著者: Shraddha Rastogi, Abhinav Joshi, Nahoko Sato, Sunmin Lee, Min-Jung Lee, Jane B. Trepel, Len Neckers - Cell Stress and Chaperones 2024 被引用: 103
- Prexasertib, a cell cycle checkpoint kinase 1 and 2 inhibitor, in BRCA wild-type recurrent high-grade serous ovarian cancer: a first-in-class proof-of-concept phase 2 study
著者: Jung‐Min Lee, Jayakumar R. Nair, Alexandra S. Zimmer, Stanley Lipkowitz, Christina M. Annunziata, Maria J. Merino, Elizabeth M. Swisher, Maria I. Harrell, Jane B. Trepel, Min-Jung Lee, Mohammadhadi Bagheri, Dana‐Adriana Botesteanu, Seth M. Steinberg, Lori M. Minasian, Irene Ekwede, Elise C. Kohn - The Lancet Oncology 2018 被引用: 212
- Durvalumab in Combination with Olaparib in Patients with Relapsed SCLC: Results from a Phase II Study
著者: Anish Thomas, Rasa Vilimas, Christopher Trindade, Rebecca Erwin-Cohen, Nitin Roper, Liqiang Xi, Venkatesh Krishnasamy, Elliot Levy, Andy Mammen, Samantha Nichols, Yuanbin Chen, Vamsidhar Velcheti, Fang Yin, Éva Szabó, Yves Pommier, Seth M. Steinberg, Jane B. Trepel, Mark Raffeld, Howard A. Young, Javed Khan, Stephen M. Hewitt, Jung-Min Lee - Journal of Thoracic Oncology 2019 被引用: 181
- Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy
著者: Nobu Oshima, Ryo Ishida, Shun Kishimoto, Kristin Beebe, Jeffrey Brender, Kazutoshi Yamamoto, Daniel J. Urban, Ganesha Rai, Michelle S. Johnson, Gloria A. Benavides, Giuseppe L. Squadrito, Dan Crooks, Joseph W. Jackson, Abhinav Joshi, Bryan T. Mott, Jonathan H. Shrimp, Michael A. Moses, Min-Jung Lee, Akira Yuno, Tobie D. Lee, Xin Hu, Tamara L. Anderson, Donna F. Kusewitt, Helen H. Hathaway, Ajit Jadhav, Didier Picard, Jane B. Trepel, James B. Mitchell, Gordon M. Stott, William Moore, Anton Simeonov, Larry A. Sklar, Jeffrey P. Norenberg, W. Marston Linehan, David J. Maloney, Chi V. Dang, Alex G. Waterson, Matthew D. Hall, Victor Darley‐Usmar, Murali C. Krishna, Leonard Μ. Neckers - Cell Reports 2020 被引用: 122
- E2112: Randomized Phase III Trial of Endocrine Therapy Plus Entinostat or Placebo in Hormone Receptor–Positive Advanced Breast Cancer. A Trial of the ECOG-ACRIN Cancer Research Group
著者: Roisín M. Connolly, Fengmin Zhao, Kathy D. Miller, Min-Jung Lee, Richard Piekarz, Karen L. Smith, Ursa Brown‐Glaberman, Jennifer S. Winn, Bryan A. Faller, Adedayo A. Onitilo, Mark E. Burkard, G. Thomas Budd, Ellis Levine, Melanie Royce, Peter A. Kaufman, Alexandra Thomas, Jane B. Trepel, Antonio C. Wolff, Joseph A. Sparano - Journal of Clinical Oncology 2021 被引用: 119
- Phase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors
著者: Anish Thomas, Christophe E. Redon, Linda Sciuto, Emerson Padiernos, Jiuping Ji, Min-Jung Lee, Akira Yuno, Sunmin Lee, Yiping Zhang, Lan Tran, William H. Yutzy, Arun Rajan, Udayan Guha, Haobin Chen, Raffit Hassan, Christine Alewine, Éva Szabó, Susan E. Bates, Robert J. Kinders, Seth M. Steinberg, James H. Doroshow, Mirit I. Aladjem, Jane B. Trepel, Yves Pommier - Journal of Clinical Oncology 2017 被引用: 174
- High‐fidelity detection and sorting of nanoscale vesicles in viral disease and cancer
著者: Aizea Morales‐Kastresana, Thomas Musich, Joshua A Welsh, William G. Telford, Thorsten Demberg, James C. S. Wood, Marty Bigos, Carley D. Ross, Aliaksander Kachynski, Alan Dean, Edward J. Felton, Jonathan Van Dyke, John Tigges, Vasilis Toxavidis, David R. Parks, W. Roy Overton, Aparna H. Kesarwala, Gordon J. Freeman, Ariel Rosner, Stephen P. Perfetto, Lise Pasquet, Masaki Terabe, Katherine McKinnon, Veena Kapoor, Jane B. Trepel, Anu Puri, Hisataka Kobayashi, Bryant C. Yung, Xiaoyuan Chen, Peter Guion, Peter L. Choyke, Susan J. Knox, Ionita Ghiran, Marjorie Robert‐Guroff, Jay A. Berzofsky, Jennifer Jones - Journal of Extracellular Vesicles 2019 被引用: 130
- HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation
著者: Toshiki Kijima, Thomas L. Prince, Megan L. Tigue, Kendrick Yim, Harvey Schwartz, Kristin Beebe, Sunmin Lee, Marek A. Budzyński, Heinric Williams, Jane B. Trepel, Lea Sistonen, Stuart K. Calderwood, Len Neckers - Scientific Reports 2018 被引用: 148
- Phase I Study of Cabozantinib and Nivolumab Alone or With Ipilimumab for Advanced or Metastatic Urothelial Carcinoma and Other Genitourinary Tumors
著者: Andrea B. Apolo, Rosa Nadal, Daniel M. Girardi, Scot A. Niglio, Lisa Ley, Lisa M. Cordes, Seth M. Steinberg, Olena Sierra Ortiz, Jacqueline Cadena, Carlos Guerrero Díaz, Marissa Mallek, Nicole N. Davarpanah, Rene Costello, Jane B. Trepel, Min-Jung Lee, Maria J. Merino, Mohammadhadi Bagheri, Paul Monk, William D. Figg, James L. Gulley, Piyush K. Agarwal, Vladimir Valera, Heather J. Chalfin, Jennifer Jones, Howard Streicher, John J. Wright, Yang‐Min Ning, Howard L. Parnes, William L. Dahut, Donald P. Bottaro, Primo N. Lara, Biren Saraiya, Sumanta K. Pal, Mark N. Stein, Amir Mortazavi - Journal of Clinical Oncology 2020 被引用: 137
- Update on Hsp90 Inhibitors in Clinical Trial
著者: Yoonhee Kim, S. Alarcon, S. Lee, M.-J. Lee, Giuseppe Giaccone, Len Neckers, Jane B. Trepel - Current Topics in Medicinal Chemistry 2009 被引用: 307
- Randomized Phase II, Double-Blind, Placebo-Controlled Study of Exemestane With or Without Entinostat in Postmenopausal Women With Locally Recurrent or Metastatic Estrogen Receptor-Positive Breast Cancer Progressing on Treatment With a Nonsteroidal Aromatase Inhibitor
著者: Denise A. Yardley, Roohi Ismail‐Khan, Bohuslav Melichar, Mikhail Lichinitser, Pamela N. Münster, Pamela Klein, Scott Cruickshank, Kathy D. Miller, Min J. Lee, Jane B. Trepel - Journal of Clinical Oncology 2013 被引用: 418
- Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutations
著者: Fatima Karzai, David James VanderWeele, Ravi A. Madan, Helen Owens, Lisa M. Cordes, Amy Hankin, Anna Couvillon, E. Hitt Nichols, Marijo Bilušić, Michael L. Beshiri, Kathleen Kelly, Venkatesh Krishnasamy, Sunmin Lee, Min-Jung Lee, Akira Yuno, Jane B. Trepel, Maria J. Merino, Ryan Dittamore, Jennifer L. Marté, Renee N. Donahue, Jeffrey Schlom, Keith Killian, Paul S. Meltzer, Seth M. Steinberg, James L. Gulley, Jung Min Lee, William L. Dahut - Journal for ImmunoTherapy of Cancer 2018 被引用: 312
- Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis
著者: Soichiro Yoshida, Shinji Tsutsumi, Guillaume Mühlebach, Carole Sourbier, Min-Jung Lee, Sunmin Lee, Evangelia Vartholomaiou, Manabu Tatokoro, Kristin Beebe, Naoto Miyajima, Robert P. Mohney, Yang Chen, Hisashi Hasumi, Wanping Xu, Hiroshi Fukushima, Ken Nakamura, Fumitaka Koga, Kazunori Kihara, Jane B. Trepel, Didier Picard, Leonard Μ. Neckers - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 被引用: 300
- Immunogenic cancer cell death selectively induced by near infrared photoimmunotherapy initiates host tumor immunity
著者: Mikako Ogawa, Yusuke Tomita, Yuko Nakamura, Min-Jung Lee, Sunmin Lee, Saori Tomita, Tadanobu Nagaya, Kazuhide Sato, Toyohiko Yamauchi, Hidenao Iwai, Abhishek Kumar, Timothy Haystead, Hari Shroff, Peter L. Choyke, Jane B. Trepel, Hisataka Kobayashi - Oncotarget 2017 被引用: 259
- IL‐1β mediated up‐regulation of HIF‐lα via an NFkB/COX‐2 pathway identifies HIF‐1 as a critical link between inflammation and oncogenesis
著者: Yunjin Jung, Jennifer S. Isaacs, Sunmin Lee, Jane B. Trepel, Len Neckers - The FASEB Journal 2003 被引用: 675
- Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: an open-label phase 2 trial
著者: Anish Thomas, Arun Rajan, Arlene Berman, Yusuke Tomita, Christina Brzezniak, Min-Jung Lee, Sunmin Lee, Alexander Ling, Aaron John Spittler, Corey A. Carter, Udayan Guha, Yisong Wang, Éva Szabó, Paul S. Meltzer, Seth M. Steinberg, Jane B. Trepel, Patrick J. Loehrer, Giuseppe Giaccone - The Lancet Oncology 2015 被引用: 299
- The Glycolytic Shift in Fumarate-Hydratase-Deficient Kidney Cancer Lowers AMPK Levels, Increases Anabolic Propensities and Lowers Cellular Iron Levels
著者: Wing‐Hang Tong, Carole Sourbier, Gennady Kovtunovych, Suh Young Jeong, Manish Vira, Manik C. Ghosh, Vladimir Valera Romero, Rachid Sougrat, Sophie Vaulont, Benoı̂t Viollet, Yeong-Sang Kim, Sunmin Lee, Jane B. Trepel, Ramaprasad Srinivasan, Gennady Bratslavsky, Youfeng Yang, W. Marston Linehan, Tracey A. Rouault - Cancer Cell 2011 被引用: 214
