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David R. Mole

2000–2025 年に発表

63
論文数
18,162
被引用数
46
h 指数
59
i10 指数

被引用数

David R. Mole の年別被引用数1990 年: 被引用 1 件1999 年: 被引用 1 件2000 年: 被引用 7 件2001 年: 被引用 87 件2002 年: 被引用 231 件2003 年: 被引用 302 件2004 年: 被引用 287 件2005 年: 被引用 265 件2006 年: 被引用 256 件2007 年: 被引用 208 件2008 年: 被引用 207 件2009 年: 被引用 241 件2010 年: 被引用 220 件2011 年: 被引用 237 件2012 年: 被引用 216 件2013 年: 被引用 251 件2014 年: 被引用 225 件2015 年: 被引用 236 件2016 年: 被引用 266 件2017 年: 被引用 242 件2018 年: 被引用 196 件2019 年: 被引用 556 件2020 年: 被引用 653 件2021 年: 被引用 610 件2022 年: 被引用 505 件2023 年: 被引用 313 件2024 年: 被引用 448 件2025 年: 被引用 203 件2026 年: 被引用 4 件1991〜1998 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 2,205 件、この内訳の 27.7%中国: 引用元論文 1,051 件、この内訳の 13.2%イギリス: 引用元論文 768 件、この内訳の 9.7%ドイツ: 引用元論文 452 件、この内訳の 5.7%日本: 引用元論文 284 件、この内訳の 3.6%カナダ: 引用元論文 281 件、この内訳の 3.5%オーストラリア: 引用元論文 232 件、この内訳の 2.9%イタリア: 引用元論文 229 件、この内訳の 2.9%フランス: 引用元論文 226 件、この内訳の 2.8%スイス: 引用元論文 155 件、この内訳の 1.9%スペイン: 引用元論文 150 件、この内訳の 1.9%韓国: 引用元論文 129 件、この内訳の 1.6%
0%27.7%その他 22.6%

機関

分野

  • Biochemistry, Genetics and Molecular Biology69.2%
  • Medicine20.4%
  • Earth and Planetary Sciences2.6%
  • Immunology and Microbiology2.6%
  • Neuroscience1.2%
  • Environmental Science0.7%
  • その他3.3%

トピック

  • Cancer, Hypoxia, and Metabolism17.9%
  • RNA modifications and cancer4.2%
  • Mitochondrial Function and Pathology3.6%
  • Epigenetics and DNA Methylation3.4%
  • High Altitude and Hypoxia3.3%
  • Cancer-related molecular mechanisms research2.5%
  • その他65.1%

共著者

全論文

検索で開く
  1. Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation

    著者: Panu Jaakkola, David R. Mole, Ya‐Min Tian, Michael Wilson, Adriana Gielbert, Simon J. Gaskell, Alex von Kriegsheim, Holger Hebestreit, Mridul Mukherji, Christopher J. Schofield, Patrick H. Maxwell, Christopher W. Pugh, Peter J. Ratcliffe - Science 2001 被引用: 5,538

  2. C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

    著者: Andrew Epstein, Jonathan Gleadle, Luke A. McNeill, Kirsty S. Hewitson, John P. O’Rourke, David R. Mole, Mridul Mukherji, Eric Metzen, Michael Wilson, Anu Dhanda, Ya‐Min Tian, Norma Masson, Donald L. Hamilton, Panu Jaakkola, Robert Barstead, Jonathan Hodgkin, Patrick H. Maxwell, Christopher W. Pugh, Christopher J. Schofield, Peter J. Ratcliffe - Cell 2001 被引用: 3,353

  3. Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer

    著者: Johannes Schödel, Steffen Grampp, Eamonn R. Maher, Holger Moch, Peter J. Ratcliffe, Paul Russo, David R. Mole - European Urology 2015 被引用: 423

  4. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

    著者: Jennifer S. Isaacs, Yun Jin Jung, David R. Mole, Sunmin Lee, Carlos A. Torres‐Cabala, Yuen‐Li Chung, Maria J. Merino, Jane B. Trepel, Berton Zbar, Jorge R. Toro, Peter J. Ratcliffe, W. Marston Linehan, Len Neckers - Cancer Cell 2005 被引用: 942

  5. High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

    著者: Johannes Schödel, Spyros Oikonomopoulos, Jiannis Ragoussis, Christopher W. Pugh, Peter J. Ratcliffe, David R. Mole - Blood 2011 被引用: 734

  6. Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

    著者: David R. Mole, Christine Blancher, Richard R. Copley, Patrick J. Pollard, Jonathan Gleadle, Jiannis Ragoussis, Peter J. Ratcliffe - Journal of Biological Chemistry 2009 被引用: 550

  7. The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes

    著者: Brian M. Ortmann, Natalie Burrows, Ian Lobb, Esther Arnaiz, Niek Wit, Peter S. J. Bailey, Louise Jordon, Olivia Lombardi, Ana Peñalver, James McCaffrey, Rachel Seear, David R. Mole, Peter J. Ratcliffe, Patrick H. Maxwell, James A. Nathan - Nature Genetics 2021 被引用: 84

  8. Inherent DNA‐binding specificities of the HIF‐1α and HIF‐2α transcription factors in chromatin

    著者: James Smythies, Min Sun, Norma Masson, Rafik Salama, Peter Simpson, Elizabeth Murray, Viviana K. Neumann, Matthew E. Cockman, Hani Choudhry, Peter J. Ratcliffe, David R. Mole - EMBO Reports 2018 被引用: 203

  9. Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein

    著者: Matthew E. Cockman, Norma Masson, David R. Mole, Panu Jaakkola, Gin-Wen Chang, Steven C. Clifford, Eamonn R. Maher, Christopher W. Pugh, Peter J. Ratcliffe, Patrick H. Maxwell - Journal of Biological Chemistry 2000 被引用: 1,047

  10. Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)

    著者: Armin Thalhammer, Zuzana Bencokova, Rachel L. Poole, Christoph Loenarz, Julie Adam, Linda O′Flaherty, Johannes Schödel, David R. Mole, Konstantinos Giaslakiotis, Christopher J. Schofield, Ester M. Hammond, Peter J. Ratcliffe, Patrick J. Pollard - PLoS ONE 2011 被引用: 153

  11. The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia

    著者: María Tiana, Bárbara Acosta‐Iborra, Laura Puente-Santamaría, Pablo Hernansanz‐Agustín, Rebecca Worsley-Hunt, Norma Masson, Francisco García‐Río, David R. Mole, Peter J. Ratcliffe, Wyeth W. Wasserman, Benilde Jiménez, Luis del Peso - Nucleic Acids Research 2017 被引用: 131

  12. Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel–Lindau Gene Mutation Status

    著者: Yosra Messai, Sophie Gad, Muhammad Zaeem Noman, Gwénaël Le Teuff, Sophie Couvé, Bassam Janji, Solenne Florence Kammerer, Nathalie Rioux-Leclerc, Meriem Hasmim, Sophie Ferlicot, Véronique Baud, Arnaud Méjean, David R. Mole, Stéphane Richard, Alexander Eggermont, Laurence Albigès, Fathia Mami‐Chouaib, Bernard Escudier, Salem Chouaı̈b - European Urology 2015 被引用: 176

  13. Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

    著者: Olivia Lombardi, Ran Li, Silvia Halim, Hani Choudhry, Peter J. Ratcliffe, David R. Mole - Cell Reports 2022 被引用: 48

  14. Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival

    著者: Hani Choudhry, Ashwag Albukhari, Matteo Morotti, Syed Haider, Daniela Moralli, James Smythies, Johannes Schödel, Catherine Green, Carme Camps, Francesca M. Buffa, Peter J. Ratcliffe, Jiannis Ragoussis, Adrian L. Harris, David R. Mole - Oncogene 2014 被引用: 313

  15. The Lysyl Oxidases LOX and LOXL2 Are Necessary and Sufficient to Repress E-cadherin in Hypoxia

    著者: Ruth Schietke, Christina Warnecke, Ingrid Wacker, Johannes Schödel, David R. Mole, Valentina Câmpean, Kerstin Amann, Margarete Goppelt‐Struebe, Jürgen Behrens, Kai‐Uwe Eckardt, Michael S. Wiesener - Journal of Biological Chemistry 2009 被引用: 251

  16. miR-210 is a target of hypoxia-inducible factors 1 and 2 in renal cancer, regulates ISCU and correlates with good prognosis

    著者: Robert McCormick, Christopher Blick, Jiannis Ragoussis, J Schoedel, David R. Mole, Anna-Mary Young, Peter J. Selby, Rosamonde E. Banks, Adrian L. Harris - British Journal of Cancer 2013 被引用: 189

  17. The formation of Neoarchean continental crust in the south-east Superior Craton by two distinct geodynamic processes

    著者: David R. Mole, P. C. Thurston, J. H. Marsh, Richard A. Stern, J. A. Ayer, Laure Martin, Yongjun Lu - Precambrian Research 2021 被引用: 102

  18. MITF controls the TCA cycle to modulate the melanoma hypoxia response

    著者: Pakavarin Louphrasitthiphol, Ioanna Ledaki, Jagat Chauhan, Paola Falletta, Robert Siddaway, Francesca M. Buffa, David R. Mole, Tomoyoshi Soga, Colin R. Goding - Pigment Cell & Melanoma Research 2019 被引用: 74

  19. Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia

    著者: Sonny Ang, Hua Chen, Kiichi Hirota, Victor R. Gordeuk, Jaroslav Jelı́nek, Yongli Guan, Enli Liu, Adelina Sergueeva, Galina Miasnikova, David R. Mole, Patrick H. Maxwell, David W. Stockton, Gregg L. Semenza, Josef T. Prchal - Nature Genetics 2002 被引用: 506

  20. Capture‐C reveals preformed chromatin interactions between HIF‐binding sites and distant promoters

    著者: James L. Platt, Rafik Salama, James Smythies, Hani Choudhry, James Davies, Jim R. Hughes, Peter J. Ratcliffe, David R. Mole - EMBO Reports 2016 被引用: 77

  21. Hypoxic Regulation of Gene Transcription and Chromatin: Cause and Effect

    著者: Jessica D. Kindrick, David R. Mole - International Journal of Molecular Sciences 2020 被引用: 58

  22. Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI

    著者: Victoria Lauer, Steffen Grampp, James L. Platt, Véronique N. Lafleur, Olivia Lombardi, Hani Choudhry, Franziska Kranz, Arndt Hartmann, Bernd Wullich, Atsushi Yamamoto, Mathew L. Coleman, Peter J. Ratcliffe, David R. Mole, Johannes Schödel - Journal of Biological Chemistry 2019 被引用: 52

  23. Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α

    著者: Patrick J. Pollard, Christoph Loenarz, David R. Mole, M.A. McDonough, Jonathan Gleadle, Christopher J. Schofield, Peter J. Ratcliffe - Biochemical Journal 2008 被引用: 293

  24. Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases

    著者: Mun Chiang Chan, Nicholas E. Ilott, Johannes Schödel, David Sims, Anthony Tumber, Kerstin Lippl, David R. Mole, Christopher W. Pugh, Peter J. Ratcliffe, Chris P. Ponting, Christopher J. Schofield - Journal of Biological Chemistry 2016 被引用: 109