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Christopher W. Pugh

1981–2025 年に発表

94
論文数
41,198
被引用数
80
h 指数
93
i10 指数

被引用数

Christopher W. Pugh の年別被引用数1926 年: 被引用 1 件1967 年: 被引用 1 件1970 年: 被引用 1 件1982 年: 被引用 7 件1983 年: 被引用 13 件1984 年: 被引用 6 件1985 年: 被引用 12 件1986 年: 被引用 19 件1987 年: 被引用 8 件1988 年: 被引用 5 件1989 年: 被引用 20 件1990 年: 被引用 11 件1991 年: 被引用 8 件1992 年: 被引用 9 件1993 年: 被引用 27 件1994 年: 被引用 21 件1995 年: 被引用 41 件1996 年: 被引用 51 件1997 年: 被引用 68 件1998 年: 被引用 121 件1999 年: 被引用 129 件2000 年: 被引用 245 件2001 年: 被引用 393 件2002 年: 被引用 608 件2003 年: 被引用 845 件2004 年: 被引用 841 件2005 年: 被引用 757 件2006 年: 被引用 702 件2007 年: 被引用 627 件2008 年: 被引用 602 件2009 年: 被引用 720 件2010 年: 被引用 541 件2011 年: 被引用 544 件2012 年: 被引用 479 件2013 年: 被引用 538 件2014 年: 被引用 392 件2015 年: 被引用 407 件2016 年: 被引用 479 件2017 年: 被引用 403 件2018 年: 被引用 353 件2019 年: 被引用 1,049 件2020 年: 被引用 1,204 件2021 年: 被引用 1,038 件2022 年: 被引用 826 件2023 年: 被引用 584 件2024 年: 被引用 873 件2025 年: 被引用 389 件2026 年: 被引用 20 件1927〜1966 年は被引用が無いため表示していません1968〜1969 年は被引用が無いため表示していません1971〜1981 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 4,001 件、この内訳の 28.8%イギリス: 引用元論文 1,437 件、この内訳の 10.3%中国: 引用元論文 1,428 件、この内訳の 10.3%ドイツ: 引用元論文 790 件、この内訳の 5.7%日本: 引用元論文 575 件、この内訳の 4.1%イタリア: 引用元論文 489 件、この内訳の 3.5%カナダ: 引用元論文 467 件、この内訳の 3.3%フランス: 引用元論文 414 件、この内訳の 3%オランダ: 引用元論文 293 件、この内訳の 2.1%スイス: 引用元論文 289 件、この内訳の 2.1%オーストラリア: 引用元論文 267 件、この内訳の 1.9%スペイン: 引用元論文 264 件、この内訳の 1.9%
0%28.8%その他 23%

機関

分野

  • Biochemistry, Genetics and Molecular Biology62.2%
  • Medicine22.6%
  • Immunology and Microbiology5.1%
  • Engineering4.5%
  • Neuroscience1.7%
  • Environmental Science0.8%
  • その他3.1%

トピック

  • Cancer, Hypoxia, and Metabolism16.1%
  • Mitochondrial Function and Pathology2.9%
  • High Altitude and Hypoxia2.6%
  • Angiogenesis and VEGF in Cancer2.4%
  • Epigenetics and DNA Methylation2.4%
  • RNA modifications and cancer2.4%
  • その他71.2%

共著者

全論文

検索で開く
  1. Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation

    著者: Panu Jaakkola, David R. Mole, Ya‐Min Tian, Michael Wilson, Adriana Gielbert, Simon J. Gaskell, Alex von Kriegsheim, Holger Hebestreit, Mridul Mukherji, Christopher J. Schofield, Patrick H. Maxwell, Christopher W. Pugh, Peter J. Ratcliffe - Science 2001 被引用: 5,538

  2. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

    著者: Patrick H. Maxwell, Michael S. Wiesener, Gin-Wen Chang, Steven C. Clifford, Emma C. Vaux, Matthew E. Cockman, Charles C. Wykoff, Christopher W. Pugh, Eamonn R. Maher, Peter J. Ratcliffe - Nature 1999 被引用: 5,225

  3. C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation

    著者: Andrew Epstein, Jonathan Gleadle, Luke A. McNeill, Kirsty S. Hewitson, John P. O’Rourke, David R. Mole, Mridul Mukherji, Eric Metzen, Michael Wilson, Anu Dhanda, Ya‐Min Tian, Norma Masson, Donald L. Hamilton, Panu Jaakkola, Robert Barstead, Jonathan Hodgkin, Patrick H. Maxwell, Christopher W. Pugh, Christopher J. Schofield, Peter J. Ratcliffe - Cell 2001 被引用: 3,353

  4. Regulation of angiogenesis by hypoxia: role of the HIF system

    著者: Christopher W. Pugh, Peter J. Ratcliffe - Nature Medicine 2003 被引用: 2,511

  5. Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL

    著者: Wai‐Ching Hon, Michael Wilson, Karl Harlos, Timothy D. W. Claridge, Christopher J. Schofield, Christopher W. Pugh, Patrick H. Maxwell, Peter J. Ratcliffe, David I. Stuart, E. Yvonne Jones - Nature 2002 被引用: 753

  6. Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

    著者: Julie Adam, Emine Hatipoglu, Linda O′Flaherty, Nicola Ternette, Natasha Sahgal, Helen Lockstone, Dilair Baban, Emma Nye, Gordon Stamp, Kathryn Wolhuter, Marcus Stevens, Román Fischer, Peter Carmeliet, Patrick H. Maxwell, Christopher W. Pugh, Norma Frizzell, Tomoyoshi Soga, Benedikt M. Kessler, Mona El‐Bahrawy, Peter J. Ratcliffe, Patrick J. Pollard - Cancer Cell 2011 被引用: 578

  7. Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor

    著者: Rebecca J. Appelhoff, Ya‐Min Tian, Raju R. Raval, Helen Turley, Adrian L. Harris, Christopher W. Pugh, Peter J. Ratcliffe, Jonathan Gleadle - Journal of Biological Chemistry 2004 被引用: 1,106

  8. High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

    著者: Johannes Schödel, Spyros Oikonomopoulos, Jiannis Ragoussis, Christopher W. Pugh, Peter J. Ratcliffe, David R. Mole - Blood 2011 被引用: 734

  9. Non-contact video-based vital sign monitoring using ambient light and auto-regressive models

    著者: Lionel Tarassenko, Mauricio Villarroel, Alessandro Guazzi, João Jorge, David A. Clifton, Christopher W. Pugh - Physiological Measurement 2014 被引用: 415

  10. Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation

    著者: Ananda S. Mirchandani, Stephen J. Jenkins, Calum C. Bain, Manuel A. Sánchez-García, Hannah Lawson, Patrícia Coelho, Fiona Murphy, David Griffith, Ailiang Zhang, Tyler Morrison, Tony Ly, Simone Arienti, Pranvera Sadiku, Emily Watts, Rebecca Dickinson, Leila Reyes, George Cooper, Sarah A. Clark, David Lewis, Van Kelly, Christos Spanos, Kathryn Musgrave, Liam Delaney, I. Harper, Jonathan Scott, Nick Parkinson, Anthony Rostron, J. Kenneth Baillie, Sara Clohisey, Clare Pridans, Lara Campana, Philip Starkey Lewis, A. John Simpson, David H. Dockrell, Jürgen Schwarze, Nikhil Hirani, Peter J. Ratcliffe, Christopher W. Pugh, Kamil R. Kranc, Stuart J. Forbes, Moira K. B. Whyte, Sarah R. Walmsley - Nature Immunology 2022 被引用: 80

  11. The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

    著者: Katherine Louise Talks, Helen Turley, Kevin C. Gatter, Patrick H. Maxwell, Christopher W. Pugh, Peter J. Ratcliffe, Adrian L. Harris - American Journal Of Pathology 2000 被引用: 1,303

  12. Widespread, hypoxia‐inducible expression of HIF‐2α in distinct cell populations of different organs

    著者: Michael S. Wiesener, Jan Steffen Jürgensen, Christian Rosenberger, Charlotte Scholze, Jan Hörstrup, Christina Warnecke, Stefano J. Mandriota, Ingo Bechmann, Ulrich Frei, Christopher W. Pugh, Peter J. Ratcliffe, Sebastian Bachmann, Patrick H. Maxwell, Kai‐Uwe Eckardt - The FASEB Journal 2002 被引用: 734

  13. Hypoxia-inducible expression of tumor-associated carbonic anhydrases.

    著者: Charles C. Wykoff, Nigel Beasley, Peter H. Watson, Kevin Turner, Jaromı́r Pastorek, Amen Sibtain, George D. Wilson, Helen Turley, Kate Talks, Patrick H. Maxwell, Christopher W. Pugh, Peter J. Ratcliffe, Adrian L. Harris - 2000 被引用: 1,284

  14. Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma

    著者: Raju R. Raval, Kah Weng Lau, Maxine Tran, Heidi Sowter, Stefano J. Mandriota, Jiliang Li, Christopher W. Pugh, Patrick H. Maxwell, Adrian L. Harris, Peter J. Ratcliffe - Molecular and Cellular Biology 2005 被引用: 933

  15. Photoplethysmographic derivation of respiratory rate: a review of relevant physiology

    著者: David Meredith, David A. Clifton, Peter Charlton, John K Brooks, Christopher W. Pugh, Lionel Tarassenko - Journal of Medical Engineering & Technology 2011 被引用: 228

  16. Multiparameter persistent homology landscapes identify immune cell spatial patterns in tumors

    著者: Oliver Vipond, Joshua A. Bull, Philip S. Macklin, Ulrike Tillmann, Christopher W. Pugh, Helen M. Byrne, Heather A. Harrington - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 被引用: 88

  17. New horizons in hypoxia signaling pathways

    著者: Christopher W. Pugh, Peter J. Ratcliffe - Experimental Cell Research 2017 被引用: 183

  18. Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

    著者: Jenny C. Taylor, Hilary C. Martin, Stefano Lise, John Broxholme, Jean‐Baptiste Cazier, Andy Rimmer, Alexander Kanapin, Gerton Lunter, Simon Fiddy, Chris Allan, A.R. Aricescu, Moustafa Attar, Christian Babbs, Jennifer Becq, David Beeson, Celeste Bento, P Bignell, Edward Blair, Veronica J. Buckle, Katherine R. Bull, Ondřej Cais, Holger Cario, Helen Chapel, Richard R. Copley, Richard J. Cornall, Jude Craft, Karin Dahan, Emma E. Davenport, Calliope A. Dendrou, Olivier Devuyst, Aimée L Fenwick, Jonathan Flint, Lars Fugger, Rodney D. Gilbert, Anne Goriely, Angie Green, Ingo H. Greger, Russell Grocock, Anja V. Gruszczyk, Robert Hastings, Edouard Hatton, Douglas R. Higgs, Adrian V. S. Hill, Chris Holmes, Malcolm F. Howard, Linda Hughes, Peter Humburg, David H. Johnson, Fredrik Karpe, Zoya Kingsbury, Usha Kini, Julian C. Knight, Jonathan Krohn, Sarah Lamble, Craig B. Langman, Lorne Lonie, Joshua Luck, Davis J. McCarthy, Simon J. McGowan, Mary Frances McMullin, Kerry A. Miller, Lisa Murray, Andrea H. Németh, M. Andrew Nesbit, David Nutt, Elizabeth Ormondroyd, Annette Oturai, Alistair T. Pagnamenta, Smita Y. Patel, Melanie J. Percy, Nayia Petousi, Paolo Piazza, Siân E. Piret, Guadalupe Polanco‐Echeverry, Niko Popitsch, Fiona Powrie, Christopher W. Pugh, Lynn Quek, Peter A. Robbins, Kathryn Robson, Alexandra Russo, Natasha Sahgal, Pauline A. van Schouwenburg, Anna Schuh, Earl D. Silverman, Alison Simmons, Per Soelberg Sørensen, Elizabeth Sweeney, John Taylor, Rajesh V. Thakker, Ian Tomlinson, Amy Trebes, Stephen R.F. Twigg, Holm H. Uhlig, Paresh Vyas, Tim J. Vyse, Steven A. Wall, Hugh Watkins, Michael P. Whyte, Lorna Witty ほか 10 名 - Nature Genetics 2015 被引用: 388

  19. Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases

    著者: Alistair T. Pagnamenta, Carlos Camps, Edoardo Giacopuzzi, John Taylor, Mona Hashim, Eduardo Calpena, Pamela J. Kaisaki, Akiko Hashimoto, Jing Yu, Edward Sanders, Ron Schweßinger, Jim R. Hughes, Gerton Lunter, Hélène Dreau, Matteo P. Ferla, Lukas Lange, Yeşim Kesim, Vassilis Ragoussis, Dimitrios V. Vavoulis, Holger Allroggen, Olaf Ansorge, Christian Babbs, Siddharth Banka, Benito Baños-Piñero, David Beeson, Tal Ben‐Ami, David Bennett, Celeste Bento, Edward Blair, Charlotte Brasch‐Andersen, Katherine R. Bull, Holger Cario, Deirdre Cilliers, Valerio Conti, E. Graham Davies, Fatima Dhalla, Beatriz Diez Dacal, Dong Yin, James E. Dunford, Renzo Guerrini, Adrian L. Harris, Jane Hartley, Georg A. Holländer, M K Javaid, Maureen A. Kane, Déirdre Kelly, Dominic F. Kelly, Samantha J.L. Knight, Alexandra Y. Kreins, Erika Kvikstad, Craig B. Langman, Tracy Lester, Kate E Lines, Simon Lord, Xin Lü, Sahar Mansour, Adnan Manzur, Reza Maroofian, Brian D. Marsden, Joanne Mason, Simon J. McGowan, Davide Mei, Hana Mlčochová, Yoshiko Murakami, Andrea H. Németh, Steven Okoli, Elizabeth Ormondroyd, Lilian Bomme Ousager, Jacqueline Palace, Smita Y. Patel, Melissa M. Pentony, Christopher W. Pugh, Abolfazl Rad, Archana Ramesh, Simone G. Riva, Irene Roberts, Noémi Roy, Outi Salminen, Kyleen D. Schilling, Caroline Scott, Arjune Sen, Conrad Smith, Mark Stevenson, Rajesh V. Thakker, Stephen R.F. Twigg, Holm H. Uhlig, Richard van Wijk, Barbara Vona, Steven A. Wall, Jing Wang, Hugh Watkins, Jaroslav Žák, Anna Schuh, Usha Kini, Andrew O.M. Wilkie, Niko Popitsch, Jenny C. Taylor - Genome Medicine 2023 被引用: 72

  20. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth

    著者: Patrick H. Maxwell, Gabi U. Dachs, Jonathan Gleadle, Lynn G. Nicholls, Adrian L. Harris, Ian J. Stratford, Oliver Hankinson, Christopher W. Pugh, Peter J. Ratcliffe - National Academy of Sciences, Proceedings of the National Academy of Sciences 1997 被引用: 1,084

  21. Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein

    著者: Matthew E. Cockman, Norma Masson, David R. Mole, Panu Jaakkola, Gin-Wen Chang, Steven C. Clifford, Eamonn R. Maher, Christopher W. Pugh, Peter J. Ratcliffe, Patrick H. Maxwell - Journal of Biological Chemistry 2000 被引用: 1,047

  22. Aberrant succination of proteins in fumarate hydratase‐deficient mice and HLRCC patients is a robust biomarker of mutation status

    著者: Chiara Bardella, Mona El‐Bahrawy, Norma Frizzell, Julie Adam, Nicola Ternette, Emine Hatipoglu, Kimberley Howarth, Linda O′Flaherty, Ian Roberts, Gareth D. H. Turner, Jennifer Taylor, Konstantinos Giaslakiotis, Valentine M. Macaulay, Adrian L. Harris, Ashish Chandra, Heli Lehtonen, Virpi Launonen, Lauri A. Aaltonen, Christopher W. Pugh, Radu Mihai, David C. Trudgian, Benedikt M. Kessler, John Baynes, Peter J. Ratcliffe, Ian Tomlinson, Patrick J. Pollard - The Journal of Pathology 2011 被引用: 279

  23. Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

    著者: Tzu‐Lan Yeh, T.M. Leissing, Martine I. Abboud, Cyrille C. Thinnes, Onur Atasoylu, James P. Holt‐Martyn, Dong Zhang, Anthony Tumber, Kerstin Lippl, Christopher T. Lohans, Ivanhoe K. H. Leung, Helen Morcrette, I.J. Clifton, Timothy D. W. Claridge, Akane Kawamura, Emily Flashman, Xin Lü, Peter J. Ratcliffe, Rasheduzzaman Chowdhury, Christopher W. Pugh, Christopher J. Schofield - Chemical Science 2017 被引用: 226

  24. Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control

    著者: Xiaotong Cheng, Maria Prange‐Barczynska, James W. Fielding, Minghao Zhang, Alana Burrell, Joanna D.C.C. Lima, Luise Eckardt, Isobel L.A. Argles, Christopher W. Pugh, Keith J. Buckler, Peter A. Robbins, Emma J. Hodson, Richard K. Bruick, Lucy Collinson, Fraydoon Rastinejad, Tammie Bishop, Peter J. Ratcliffe - Journal of Clinical Investigation 2020 被引用: 58