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B. Kevin Park

1982–2025 年に発表

別表記
B.Kevin Park · B Kevin Park
146
論文数
25,885
被引用数
92
h 指数
145
i10 指数

被引用数

B. Kevin Park の年別被引用数1975 年: 被引用 1 件1984 年: 被引用 2 件1985 年: 被引用 1 件1988 年: 被引用 2 件1989 年: 被引用 4 件1990 年: 被引用 6 件1992 年: 被引用 9 件1993 年: 被引用 14 件1994 年: 被引用 9 件1995 年: 被引用 13 件1996 年: 被引用 17 件1997 年: 被引用 21 件1998 年: 被引用 47 件1999 年: 被引用 20 件2000 年: 被引用 50 件2001 年: 被引用 53 件2002 年: 被引用 100 件2003 年: 被引用 125 件2004 年: 被引用 130 件2005 年: 被引用 154 件2006 年: 被引用 148 件2007 年: 被引用 144 件2008 年: 被引用 147 件2009 年: 被引用 186 件2010 年: 被引用 233 件2011 年: 被引用 267 件2012 年: 被引用 311 件2013 年: 被引用 338 件2014 年: 被引用 318 件2015 年: 被引用 312 件2016 年: 被引用 351 件2017 年: 被引用 328 件2018 年: 被引用 295 件2019 年: 被引用 906 件2020 年: 被引用 879 件2021 年: 被引用 747 件2022 年: 被引用 534 件2023 年: 被引用 341 件2024 年: 被引用 506 件2025 年: 被引用 221 件2026 年: 被引用 8 件1976〜1983 年は被引用が無いため表示していません1986〜1987 年は被引用が無いため表示していません1991 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 2,009 件、この内訳の 20.2%中国: 引用元論文 1,072 件、この内訳の 10.8%イギリス: 引用元論文 1,025 件、この内訳の 10.3%ドイツ: 引用元論文 594 件、この内訳の 6%イタリア: 引用元論文 317 件、この内訳の 3.2%フランス: 引用元論文 312 件、この内訳の 3.1%インド: 引用元論文 290 件、この内訳の 2.9%スウェーデン: 引用元論文 284 件、この内訳の 2.9%スペイン: 引用元論文 283 件、この内訳の 2.9%スイス: 引用元論文 280 件、この内訳の 2.8%オーストラリア: 引用元論文 273 件、この内訳の 2.7%日本: 引用元論文 251 件、この内訳の 2.5%
0%20.2%その他 29.7%

機関

分野

  • Medicine39.2%
  • Biochemistry, Genetics and Molecular Biology23.5%
  • Pharmacology, Toxicology and Pharmaceutics18.3%
  • Engineering3.6%
  • Computer Science3.5%
  • Immunology and Microbiology2.8%
  • その他9.1%

トピック

  • Pharmacogenetics and Drug Metabolism4.5%
  • Drug-Induced Hepatotoxicity and Protection4.4%
  • Genomics, phytochemicals, and oxidative stress4%
  • Computational Drug Discovery Methods3.4%
  • Drug-Induced Adverse Reactions2.8%
  • Liver physiology and pathology2.6%
  • その他78.3%

共著者

全論文

検索で開く
  1. The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation

    著者: Holly K. Bryan, Adedamola Olayanju, Christopher E. Goldring, B. Kevin Park - Biochemical Pharmacology 2012 被引用: 1,015

  2. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients

    著者: Munir Pirmohamed, Sally James, Shaun Meakin, Chris Green, Andrew Scott, Thomas Walley, Keith Farrar, B Kevin Park, Alasdair Breckenridge - BMJ 2004 被引用: 3,228

  3. Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

    著者: Catherine C. Bell, Delilah Hendriks, Sabrina Moro, Ewa Ellis, Joanne Walsh, Anna Renblom, Lisa Fredriksson Puigvert, Anita C. A. Dankers, Frank Jacobs, Jan Snoeys, Rowena Sison‐Young, Rosalind E. Jenkins, Åsa Nordling, Souren Mkrtchian, B. Kevin Park, Neil R. Kitteringham, Christopher E. Goldring, Volker M. Lauschke, Magnus Ingelman‐Sundberg - Scientific Reports 2016 被引用: 708

  4. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

    著者: Patrício Godoy, Nicola J. Hewitt, Ute Albrecht, Melvin E. Andersen, Nariman Ansari, Sudin Bhattacharya, Johannes G. Bode, Jennifer Bolleyn, Christoph Borner, J Böttger, Albert Braeuning, Robert A. Budinsky, Britta Burkhardt, Neil R. Cameron, Giovanni Camussi, Chong-Su Cho, Yun-Jaie Choi, J. Craig Rowlands, Uta Dahmen, Georg Damm, Olaf Dirsch, M. Teresa Donato, Jian Dong, Steven Dooley, Dirk Drasdo, Rowena Eakins, Karine Sá Ferreira, Valentina Fonsato, Joanna Fraczek, Rolf Gebhardt, Andrew Gibson, Matthias Glanemann, Christopher E. Goldring, Marı́a José Gómez-Lechón, Geny M. M. Groothuis, Lena Gustavsson, Christelle Guyot, David Hallifax, Seddik Hammad, Adam S. Hayward, Dieter Häussinger, Claus Hellerbrand, Philip Hewitt, Stefan Hoehme, Hermann−Georg Holzhütter, J. Brian Houston, Jens Hrach, Kiyomi Ito, Hartmut Jaeschke, Verena Keitel, Jens Kelm, B. Kevin Park, Claus Kordes, Gerd A. Kullak‐Ublick, Edward L. LeCluyse, Peng Lü, Jennifer L. Luebke-Wheeler, Anna Lutz, Daniel J. Maltman, Madlen Matz‐Soja, Patrick D. McMullen, Irmgard Merfort, Simon Messner, Christoph Meyer, Jessica Mwinyi, Dean J. Naisbitt, Andreas K. Nüssler, Peter Olinga, Francesco Pampaloni, Jingbo Pi, Linda Pluta, Stefan Przyborski, Anup Ramachandran, Vera Rogiers, Cliff Rowe, Celine Schelcher, Kathrin Schmich, Michael Schwarz, Bijay Singh, Ernst H. K. Stelzer, Bruno Stieger, Regina Stöber, Yuichi Sugiyama, Ciro Tetta, Wolfgang E. Thasler, Tamara Vanhaecke, Mathieu Vinken, Thomas S. Weiß, A Widera, Courtney G. Woods, Jinghai J. Xu, Kathy Yarborough, Jan G. Hengstler - Archives of Toxicology 2013 被引用: 1,275

  5. Alternatively activated macrophages promote resolution of necrosis following acute liver injury

    著者: Philip Starkey Lewis, Lara Campana, Niya Aleksieva, Jennifer A. Cartwright, Alison C. MacKinnon, Eoghan O’Duibhir, Timothy J. Kendall, Matthieu Vermeren, Adrian Thomson, Victoria L. Gadd, Benjamin J. Dwyer, Rhona Aird, Tak‐Yung Man, Adriano G. Rossi, Lesley M. Forrester, B. Kevin Park, Stuart J. Forbes - Journal of Hepatology 2020 被引用: 226

  6. Managing the challenge of drug-induced liver injury: a roadmap for the development and deployment of preclinical predictive models

    著者: Richard Weaver, Eric A.G. Blomme, Amy E. Chadwick, Ian M. Copple, Helga H.J. Gerets, Christopher E. Goldring, André Guillouzo, Philip Hewitt, Magnus Ingelman‐Sundberg, Klaus Gjervig Jensen, Satu Juhila, Ursula Klingmüller, Gilles Labbe, Michael J. Liguori, Cerys Lovatt, Paul Morgan, Dean J. Naisbitt, Raymond Pieters, Jan Snoeys, Bob van de Water, Dominic P. Williams, B. Kevin Park - Nature Reviews Drug Discovery 2019 被引用: 247

  7. Managing the challenge of chemically reactive metabolites in drug development

    著者: B. Kevin Park, Alan R. Boobis, Stephen E. Clarke, Christopher E. Goldring, David Jones, J. Gerry Kenna, Craig Lambert, Hugh Laverty, Dean J. Naisbitt, Sidney D. Nelson, Deborah A. Nicoll‐Griffith, R. Scott Obach, Philip A. Routledge, Dennis A. Smith, Donald Tweedie, Nico Vermeulen, Dominic P. Williams, Ian D. Wilson, Thomas A. Baillie - Nature Reviews Drug Discovery 2011 被引用: 455

  8. HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

    著者: for the DILIGEN study, Ann K. Daly, Peter T. Donaldson, Pallav Bhatnagar, Yufeng Shen, Itsik Pe’er, Aris Floratos, Mark J. Daly, David B. Goldstein, Sally John, Matthew R. Nelson, Julia Graham, B. Kevin Park, John Dillon, William Bernal, Heather J. Cordell, Munir Pirmohamed, Guruprasad P. Aithal, Christopher P. Day - Nature Genetics 2009 被引用: 1,043

  9. Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

    著者: Mingzhan Xue, Naila Rabbani, Hiroshi Momiji, Precious Imbasi, M. Maqsud Anwar, Neil R. Kitteringham, B. Kevin Park, Tomokazu Souma, Takashi Moriguchi, Masayuki Yamamoto, Paul J. Thornalley - Biochemical Journal 2011 被引用: 294

  10. Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway

    著者: Ian M. Copple, Adam Lister, Akua D. Obeng, Neil R. Kitteringham, Rosalind E. Jenkins, Robert Layfield, Brian Foster, Christopher E. Goldring, B. Kevin Park - Journal of Biological Chemistry 2010 被引用: 266

  11. Challenges and approaches for the development of safer immunomodulatory biologics

    著者: Jean G. Sathish, Swaminathan Sethu, Marie-Christine Bielsky, Lolke de Haan, Neil French, Karthik Govindappa, James Green, C.E.M. Griffiths, Stephen T. Holgate, David Jones, Ian Kimber, Jonathan G. Moggs, Dean J. Naisbitt, Munir Pirmohamed, Gabriele Reichmann, Jennifer Sims, Meena Subramanyam, Marque D. Todd, Jan Willem van der Laan, Richard Weaver, B. Kevin Park - Nature Reviews Drug Discovery 2013 被引用: 178

  12. Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity—implications for therapeutic targeting of Nrf2

    著者: Adedamola Olayanju, Ian M. Copple, Holly K. Bryan, George T. Edge, Rowena L. C. Sison, Min Wei Wong, Zhengquan Lai, Zhi‐Xiu Lin, Karen Dunn, Christopher M. Sanderson, Ahmad F. Alghanem, Michael Cross, Ewa Ellis, Magnus Ingelman‐Sundberg, Hassan Malik, Neil R. Kitteringham, Christopher E. Goldring, B. Kevin Park - Free Radical Biology and Medicine 2014 被引用: 235

  13. Role of Nrf2 in protection against acute kidney injury

    著者: Luke M. Shelton, B. Kevin Park, Ian M. Copple - Kidney International 2013 被引用: 195

  14. Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver

    著者: Neil R. Kitteringham, Azman Abdullah, Joanne Walsh, Laura E. Randle, Rosalind E. Jenkins, Rowena L. C. Sison, Christopher E. Goldring, Helen Powell, Christopher M. Sanderson, Samantha Williams, Larry G. Higgins, Masayuki Yamamoto, John D. Hayes, B. Kevin Park - Journal of Proteomics 2010 被引用: 169

  15. Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis

    著者: Benjamin L. Woolbright, Kenneth Dorko, Daniel J. Antoine, Joanna I. Clarke, Parviz Gholami, Feng Li, Sean Kumer, Timothy M. Schmitt, Jameson Forster, Fang Fan, Rosalind E. Jenkins, B. Kevin Park, Bruno Hagenbuch, Mojtaba Olyaee, Hartmut Jaeschke - Toxicology and Applied Pharmacology 2015 被引用: 188

  16. HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

    著者: Mark McCormack, Ana Alfirevic, Stéphane Bourgeois, John Farrell, Dalia Kasperavičiūtė, Mary Carrington, Graeme J. Sills, Tony Marson, Xiaoming Jia, Paul I. W. de Bakker, Krishna Chinthapalli, Mariam Molokhia, Michael R. Johnson, Gerard D. O’Connor, Elijah Chaila, Saud Alhusaini, Kevin V. Shianna, Rodney A. Radtke, Erin L. Heinzen, Nicole Walley, Massimo Pandolfo, Werner J. Pichler, B. Kevin Park, Chantal Depondt, Sanjay M. Sisodiya, David B. Goldstein, Panos Deloukas, Norman Delanty, Gianpiero L. Cavalleri, Munir Pirmohamed - New England Journal of Medicine 2011 被引用: 913

  17. Pharmacological Activation of Nrf2 Enhances Functional Liver Regeneration

    著者: Benjamin Chan, Mohamed Elmasry, Shiva S. Forootan, Giusy Russomanno, Tobias Bunday, Fang Zhang, Nathalie Brillant, Philip Starkey Lewis, Rhona Aird, Emanuele Ricci, Timothy Andrews, Rowena Sison‐Young, Amy Schofield, Yongxiang Fang, Adam Lister, Jack Sharkey, Harish Poptani, Neil R. Kitteringham, Stuart J. Forbes, Hassan Malik, Stephen W. Fenwick, B. Kevin Park, Christopher E. Goldring, Ian M. Copple - Hepatology 2021 被引用: 54

  18. THE ROLE OF METABOLIC ACTIVATION IN DRUG-INDUCED HEPATOTOXICITY

    著者: B. Kevin Park, Neil R. Kitteringham, James L. Maggs, Munir Pirmohamed, Dominic P. Williams - The Annual Review of Pharmacology and Toxicology 2004 被引用: 453

  19. Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy

    著者: Adam Lister, Taoufik Nedjadi, Neil R. Kitteringham, Fiona Campbell, Eithne Costello, Bryony H. Lloyd, Ian M. Copple, Samantha Williams, Andrew Owen, John P. Neoptolemos, Christopher E. Goldring, B. Kevin Park - Molecular Cancer 2011 被引用: 240

  20. RETRACTED: CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure

    著者: Benjamin M. Stutchfield, Daniel J. Antoine, Alison C. MacKinnon, Debbie Gow, Calum C. Bain, Catherine Alice Hawley, Michael Hughes, Ben Francis, Davina Wojtacha, Tak Yung Man, James W. Dear, Luke Devey, Alan M. Mowat, Jeffrey W. Pollard, B. Kevin Park, Stephen J. Jenkins, Kenneth J. Simpson, David Hume, Stephen J. Wigmore, Stuart J. Forbes - Gastroenterology 2015 被引用: 184

  21. The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death

    著者: Laleh Kamalian, Amy E. Chadwick, Mark Bayliss, Neil French, Mario Monshouwer, Jan Snoeys, B. Kevin Park - Toxicology in Vitro 2015 被引用: 154

  22. Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile

    著者: James A. Heslop, Cliff Rowe, Joanne Walsh, Rowena Sison‐Young, Roz Jenkins, Laleh Kamalian, Richard Kia, David C. Hay, Robert Jones, Hassan Malik, Stephen W. Fenwick, Amy E. Chadwick, John Mills, Neil R. Kitteringham, Christopher E. Goldring, B. Kevin Park - Archives of Toxicology 2016 被引用: 141

  23. Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication

    著者: Rowena Sison‐Young, Dimitra Mitsa, Rosalind E. Jenkins, David R. Mottram, Eliane Alexandre, Lysiane Richert, Hélène Aerts, Richard Weaver, Robert Jones, Esther Johann, Philip Hewitt, Magnus Ingelman‐Sundberg, Christopher E. Goldring, Neil R. Kitteringham, B. Kevin Park - Toxicological Sciences 2015 被引用: 92

  24. Effects of Fluorine Substitution on Drug Metabolism: Pharmacological and Toxicological Implications

    著者: B. Kevin Park, Neil R. Kitteringham - Drug Metabolism Reviews 1994 被引用: 140