Christoph Lengauer
1992–2024 年に発表
- 82
- 論文数
- 43,830
- 被引用数
- 77
- h 指数
- 82
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology59%
- Medicine33.9%
- Immunology and Microbiology1.8%
- Neuroscience1.1%
- Agricultural and Biological Sciences0.8%
- Computer Science0.7%
- その他2.7%
トピック
- Cancer-related Molecular Pathways4.9%
- Epigenetics and DNA Methylation3.9%
- Microtubule and mitosis dynamics3.7%
- Cancer Genomics and Diagnostics3.6%
- DNA Repair Mechanisms3.4%
- Genetic factors in colorectal cancer3%
- その他77.5%
共著者
- Bert Vogelstein42
- Kenneth W. Kinzler33
- Victor E. Velculescu14
- Sanford D. Markowitz10
- James K. V. Willson8
- Prasad V. Jallepalli7
- Alberto Bardelli6
- Carlo Rago6
- Harith Rajagopalan6
- Joseph L. Kim6
- Luis A. Díaz6
- Michael R. Speicher6
- Daniel P. Cahill5
- Fred Bunz5
- Jordan M. Cummins5
- Marion Dorsch5
- Martin A. Nowak5
- Nicolas Stransky5
- Thomas Cremer5
- Erica Evans4
- Franziska Michor4
- K W Kinzler4
- Michael P. Sheets4
- Natasja Brooijmans4
全論文
- Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention
著者: Anne Marie Lennon, Adam H. Buchanan, Isaac Kinde, Andrew Warren, Ashley Honushefsky, Ariella Cohain, David H. Ledbetter, Fred Sanfilippo, Kathleen Sheridan, Dillenia Rosica, Christian S. Adonizio, Hee Jung Hwang, Kamel Lahouel, Joshua D. Cohen, Christopher Douville, Aalpen A. Patel, Leonardo N. Hagmann, David D.K. Rolston, Nirav Malani, Shibin Zhou, Chetan Bettegowda, David L. Diehl, Bobbi Urban, Christopher D. Still, Lisa Kann, Julie Woods, Zachary Salvati, Joseph Vadakara, Rosemary Leeming, Prianka Bhattacharya, Carroll N. Walter, Alex Parker, Christoph Lengauer, Alison P. Klein, Cristian Tomasetti, Elliot K. Fishman, Ralph H. Hruban, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos - Science 2020 被引用: 676
- Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
著者: Shih-Min A. Huang, Yuji Mishina, Shanming Liu, Atwood K. Cheung, Frank Stegmeier, Gregory A. Michaud, Olga Charlat, Elizabeth L. Wiellette, Yue Zhang, Stephanie Wiessner, Marc Hild, Xiaoying Shi, Christopher J. Wilson, Craig Mickanin, Vic E. Myer, Aleem Fazal, Ronald Tomlinson, Fabrizio C. Serluca, Wenlin Shao, Hong Cheng, Michael D. Shultz, Christina Rau, Markus Schirle, Judith Schlegl, Sonja Ghidelli, Stephen E. Fawell, Chuang Lu, Daniel Curtis, Marc W. Kirschner, Christoph Lengauer, Peter M. Finan, John A. Tallarico, Tewis Bouwmeester, Jeffery A. Porter, Andreas Bauer, Feng Cong - Nature 2009 被引用: 2,099
- The landscape of kinase fusions in cancer
著者: Nicolas Stransky, Ethan Cerami, Stefanie S. Schalm, Joseph L. Kim, Christoph Lengauer - Nature Communications 2014 被引用: 969
- Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells
著者: Jihye Yun, Carlo Rago, Ian Cheong, Ray Pagliarini, Philipp Angenendt, Harith Rajagopalan, Kerstin Schmidt, James K. V. Willson, Sandy D. Markowitz, Shibin Zhou, Luis A. Díaz, Victor E. Velculescu, Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein, Nickolas Papadopoulos - Science 2009 被引用: 912
- First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma
著者: Richard D. Kim, Debashis Sarker, Tim Meyer, Thomas Yau, Teresa Macarulla, Joong‐Won Park, Su Pin Choo, Antoine Hollebecque, Max W. Sung, Ho-Yeong Lim, Vincenzo Mazzaferro, Joerg Trojan, Andrew X. Zhu, Jung‐Hwan Yoon, Sunil Sharma, Zhong-Zhe Lin, Stephen L. Chan, Sandrine Faivre, Lynn G. Feun, Chia-Jui Yen, Jean‐François Dufour, Daniel H. Palmer, Josep M. Llovet, Melissa Manoogian, Meera Tugnait, Nicolas Stransky, Margit Hagel, Nancy E. Kohl, Christoph Lengauer, Cori Ann Sherwin, Oleg Schmidt‐Kittler, Klaus P. Hoeflich, Hongliang Shi, Beni B. Wolf, Yoon‐Koo Kang - Cancer Discovery 2019 被引用: 250
- Genetic instabilities in human cancers
著者: Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein - Nature 1998 被引用: 4,179
- Single-vector inducible lentiviral RNAi system for oncology target validation
著者: Dmitri Wiederschain, W Nicolson Susan, Lin Chen, Alice Loo, Guizhi Yang, Alan Huang, Yan Chen, Giordano Caponigro, Yung-Mae Yao, Christoph Lengauer, William R. Sellers, John D. Benson - Cell Cycle 2009 被引用: 461
- Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
著者: Fred Bunz, Annie Dutriaux, Christoph Lengauer, Todd Waldman, Steven Zhou, Jeremy Brown, John M. Sedivy, Kenneth W. Kinzler, Bert Vogelstein - Science 1998 被引用: 2,817
- Mutant PIK3CA promotes cell growth and invasion of human cancer cells
著者: Yardena Samuels, Luis A. Díaz, Oleg Schmidt‐Kittler, Jordan M. Cummins, Laura J. DeLong, Ian Cheong, Carlo Rago, David L. Huso, Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu - Cancer Cell 2005 被引用: 919
- Precision Targeted Therapy with BLU-667 for RET-Driven Cancers
著者: Vivek Subbiah, Justin F. Gainor, Rami Rahal, Jason D. Brubaker, Joseph L. Kim, Michelle Maynard, Wei Hu, Qiongfang Cao, Michael P. Sheets, Douglas Wilson, Kevin Wilson, Lucian DiPietro, Paul Fleming, Michael Palmer, Mimi I. Hu, Lori J. Wirth, Marcia S. Brose, Sai‐Hong Ignatius Ou, Matthew H. Taylor, Elena Garralda, Steven P. Miller, Beni B. Wolf, Christoph Lengauer, Timothy J. Guzi, Erica Evans - Cancer Discovery 2018 被引用: 393
- First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway
著者: Margit Hagel, Chandra Miduturu, Michael P. Sheets, Nooreen Rubin, Weifan Weng, Nicolas Stransky, Neil Bifulco, Joseph L. Kim, Brian L. Hodous, Natasja Brooijmans, Adam Shutes, Christopher Winter, Christoph Lengauer, Nancy E. Kohl, Timothy J. Guzi - Cancer Discovery 2015 被引用: 315
- Genes Expressed in Human Tumor Endothelium
著者: Brad St. Croix, Carlo Rago, Victor E. Velculescu, Giovanni Traverso, Katharine Romans, Elizabeth A. Montgomery, Anita Lal, Gregory J. Riggins, Christoph Lengauer, Bert Vogelstein, Kenneth W. Kinzler - Science 2000 被引用: 1,854
- Genetic instability in colorectal cancers
著者: Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein - Nature 1997 被引用: 2,002
- PI3K Pathway Activation Mediates Resistance to MEK Inhibitors in KRAS Mutant Cancers
著者: Susan Wee, Zainab Jagani, Kay X. Xiang, Alice Loo, Marion Dorsch, Yung‐Mae Yao, William R. Sellers, Christoph Lengauer, Frank Stegmeier - Cancer Research 2009 被引用: 455
- DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
著者: Ina Rhee, Kurtis E. Bachman, Ben Ho Park, Kam-Wing Jair, Ray-Whay Chiu Yen, Kornel E. Schuebel, Hengmi Cui, Andrew P. Feinberg, Christoph Lengauer, Kenneth W. Kinzler, Stephen B. Baylin, Bert Vogelstein - Nature 2002 被引用: 1,250
- Crystal structure of human CDK4 in complex with a D-type cyclin
著者: Philip J. Day, Anne Cleasby, Ian J. Tickle, Marc O’Reilly, Joe E. Coyle, Finn P. Holding, Rachel McMenamin, Jeff Yon, Rajiv Chopra, Christoph Lengauer, Harren Jhoti - National Academy of Sciences, Proceedings of the National Academy of Sciences 2009 被引用: 231
- PTEN-deficient cancers depend on PIK3CB
著者: Susan Wee, Dmitri Wiederschain, Sauveur-Michel Maira, Alice Loo, Christine Miller, Rosalie deBeaumont, Frank Stegmeier, Yung-Mae Yao, Christoph Lengauer - National Academy of Sciences, Proceedings of the National Academy of Sciences 2008 被引用: 552
- Targeting cancer with kinase inhibitors
著者: Stefan Groß, Rami Rahal, Nicolas Stransky, Christoph Lengauer, Klaus P. Hoeflich - Journal of Clinical Investigation 2015 被引用: 449
- RAF/RAS oncogenes and mismatch-repair status
著者: Harith Rajagopalan, Alberto Bardelli, Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu - Nature 2002 被引用: 1,226
- Disruption of HAUSP gene stabilizes p53
著者: Jordan M. Cummins, Carlo Rago, Manu Kohli, Kenneth W. Kinzler, Christoph Lengauer, Bert Vogelstein - Nature 2004 被引用: 383
- Acquired On-Target Clinical Resistance Validates FGFR4 as a Driver of Hepatocellular Carcinoma
著者: Megan Hatlen, Oleg Schmidt-Kittler, Cori Ann Sherwin, Emily Rozsahegyi, Nooreen Rubin, Michael P. Sheets, Joseph L. Kim, Chandrasekhar V. Miduturu, Neil Bifulco, Natasja Brooijmans, Hongliang Shi, Timothy J. Guzi, Andy Boral, Christoph Lengauer, Marion Dorsch, Richard D. Kim, Yoon‐Koo Kang, Beni B. Wolf, Klaus P. Hoeflich - Cancer Discovery 2019 被引用: 109
- Somatic mutations of the mitochondrial genome in human colorectal tumours
著者: Kornélia Polyák, Yunbo Li, Hong Zhu, Christoph Lengauer, James K. V. Willson, Sanford D. Markowitz, Michael A. Trush, K W Kinzler, Bert Vogelstein - Nature Genetics 1998 被引用: 838
- Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma
著者: Silvia Buonamici, Juliet Williams, Michael Morrissey, Anlai Wang, Ribo Guo, Anthony Vattay, Kathy Hsiao, Jing Yuan, John Green, Beatriz Muñoz, Qunyan Yu, Lance Ostrom, Paul Fordjour, Dustin L. Anderson, John E. Monahan, Joseph F. Kelleher, Stefan Peukert, Shifeng Pan, Xu Wu, Sauveur-Michel Maira, Carlos Garcı́a-Echeverrı́a, Kimberly J. Briggs, D. Neil Watkins, Yung-Mae Yao, Christoph Lengauer, Markus Warmuth, William R. Sellers, Marion Dorsch - Science Translational Medicine 2010 被引用: 554
- The role of chromosomal instability in tumor initiation
著者: Martin A. Nowak, Natalia L. Komarova, Anirvan M. Sengupta, Prasad V. Jallepalli, Ie‐Ming Shih, Bert Vogelstein, Christoph Lengauer - National Academy of Sciences, Proceedings of the National Academy of Sciences 2002 被引用: 544
