David S. Park
1953–2025 年に発表
- 別表記
- David S Park
- 111
- 論文数
- 21,753
- 被引用数
- 87
- h 指数
- 110
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine43.6%
- Biochemistry, Genetics and Molecular Biology37.5%
- Neuroscience9.7%
- Computer Science1.8%
- Immunology and Microbiology1.5%
- Engineering1%
- その他4.9%
トピック
- Mitochondrial Function and Pathology7.4%
- Parkinson's Disease Mechanisms and Treatments7.1%
- Autophagy in Disease and Therapy5.9%
- Alzheimer's disease research and treatments3.2%
- Cell death mechanisms and regulation2.7%
- Neuroinflammation and Neurodegeneration Mechanisms2.3%
- その他71.4%
共著者
- Ruth S. Slack56
- Steve Callaghan16
- Jason G. MacLaurin15
- Lloyd A. Greene11
- Sean P. Cregan10
- Steven Callaghan9
- Hossein Aleyasin8
- Leonidas Stefanis8
- Patrice D. Smith8
- Tak W. Mak8
- Dianbo Qu7
- Erick J. Morris7
- Hymie Anisman7
- Jacqueline L. Vanderluit7
- Matthew Mount7
- Michael J. O’Hare7
- Shawn Hayley7
- Alvin Joselin6
- Diane C. Lagace6
- Elizabeth Keramaris6
- Heidi M. McBride6
- Maxime W.C. Rousseaux6
- Raymond H. Kim6
- Stephen J. Crocker6
全論文
- Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program
著者: Mireille Khacho, Alysen Clark, Devon S. Svoboda, Joëlle Azzi, Jason G. MacLaurin, Cynthia Meghaizel, Hiromi Sesaki, Diane C. Lagace, Marc Germain, Mary‐Ellen Harper, David S. Park, Ruth S. Slack - Cell stem cell 2016 被引用: 687
- Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
著者: Andrew W Greene, Karl Grenier, Miguel Aguileta, Stephanie Muise, Rasoul Farazifard, M. Emdadul Haque, Heidi M. McBride, David S Park, Edward A. Fon - EMBO Reports 2012 被引用: 702
- β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson’s disease
著者: Shuchi Mittal, Kjetil Bjørnevik, Doo Soon Im, Adrian Flierl, Xianjun Dong, Joseph J. Locascio, Kristine M. Abo, Elizabeth Long, Ming Jin, Bing Xu, Yang K. Xiang, Jean‐Christophe Rochet, Anders Engeland, Patrizia Rizzu, Peter Heutink, Tim Bartels, Dennis J. Selkoe, Barbara J. Caldarone, Marcie A. Glicksman, Vikram Khurana, Birgitt Schüle, David S. Park, Trond Riise, Clemens R. Scherzer - Science 2017 被引用: 437
- OPA1‐dependent cristae modulation is essential for cellular adaptation to metabolic demand
著者: David A. Patten, Jacob Wong, Mireille Khacho, Vincent Soubannier, Ryan J. Mailloux, Karine Pilon‐Larose, Jason G. MacLaurin, David S Park, Heidi M. McBride, Laura Trinkle‐Mulcahy, Mary‐Ellen Harper, Marc Germain, Ruth S. Slack - The EMBO Journal 2014 被引用: 403
- Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission
著者: Ruben K. Dagda, Salvatore J. Cherra, Scott Kulich, Anurag Tandon, David S. Park, Charleen T. Chu - Journal of Biological Chemistry 2009 被引用: 955
- Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts
著者: Aruna Kode, John S. Manavalan, Ioanna Mosialou, Govind Bhagat, Chozha Vendan Rathinam, Na Luo, Hossein Khiabanian, Albert Lee, Vundavalli V. Murty, Richard A. Friedman, Andrea M. Brum, David S. Park, Naomi Galili, Siddhartha Mukherjee, Julie Teruya‐Feldstein, Azra Raza, Raúl Rabadán, Ellin Berman, Stavroula Kousteni - Nature 2014 被引用: 516
- Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis
著者: Mireille Khacho, Alysen Clark, Devon S. Svoboda, Jason G. MacLaurin, Diane C. Lagace, David S. Park, Ruth S. Slack - Human Molecular Genetics 2017 被引用: 189
- Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
著者: Raymond H. Kim, Patrice D. Smith, Hossein Aleyasin, Shawn Hayley, Matthew Mount, Scott Pownall, Andrew Wakeham, Annick You-Ten, Suneil K. Kalia, Patrick Horne, David Westaway, Andrés M. Lozano, Hymie Anisman, David S. Park, Tak W. Mak - National Academy of Sciences, Proceedings of the National Academy of Sciences 2005 被引用: 707
- Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
著者: Isabella Irrcher, Hossein Aleyasin, Erin L. Seifert, Sarah J. Hewitt, Shivani Chhabra, Melissa Phillips, A. Kathrin Lutz, Maxime W.C. Rousseaux, Lisa Bevilacqua, Arezu Jahani‐Asl, Steve Callaghan, Jason G. MacLaurin, Konstanze F. Winklhofer, Patrizia Rizzu, Peter Rippstein, Raymond H. Kim, C.X. Chen, Edward A. Fon, Ruth S. Slack, Mary‐Ellen Harper, Heidi M. McBride, Tak W. Mak, David S. Park - Human Molecular Genetics 2010 被引用: 382
- Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases
著者: Niamh M. C. Connolly, Pierre Theurey, Vera Ádám‐Vizi, Nicolás G. Bazán, Paolo Bernardi, Juan P. Bolaños, Carsten Culmsee, Valina L. Dawson, Mohanish Deshmukh, Michael R. Duchen, Heiko Düßmann, Gary Fiskum, Marı́a F. Galindo, Giles E. Hardingham, J. Marie Hardwick, Mika B. Jekabsons, Elizabeth A. Jonas, Joaquı́n Jordán, Stuart A. Lipton, Giovanni Manfredi, Mark P. Mattson, BethAnn McLaughlin, Axel Methner, Anne N. Murphy, Michael P. Murphy, David G. Nicholls, Brian M. Polster, Tullio Pozzan, Rosario Rizzuto, Jorgina Satrústegui, Ruth S. Slack, Raymond A. Swanson, Russell H. Swerdlow, Yvonne Will, Zheng Ying, Alvin Joselin, Anna Gioran, Catarina Moreira Pinho, Orla Watters, Manuela Salvucci, Irene Llorente‐Folch, David S. Park, Daniele Bano, Maria Ankarcrona, Paola Pizzo, Jochen H.M. Prehn - Cell Death and Differentiation 2017 被引用: 208
- Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress
著者: Lennart N. Bouman, Anita Schlierf, A. Kathrin Lutz, Jixiu Shan, Alexandra Deinlein, Jürgen Kast, Zohreh Galehdar, V Palmisano, N Patenge, Daniela Berg, Thomas Gasser, René Augustin, Dietrich Trümbach, Isabella Irrcher, David S. Park, Wolfgang Wurst, M S Kilberg, Jörg Tatzelt, Konstanze F. Winklhofer - Cell Death and Differentiation 2010 被引用: 343
- Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4–CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA
著者: Zohreh Galehdar, Patrick Swan, Benjamin J. Fuerth, Steven Callaghan, David S. Park, Sean P. Cregan - Journal of Neuroscience 2010 被引用: 352
- Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival
著者: Mireille Khacho, Michelle Tarabay, David A. Patten, Pamela Khacho, Jason G. MacLaurin, Jennifer Guadagno, Richard Bergeron, Sean P. Cregan, Mary‐Ellen Harper, David S. Park, Ruth S. Slack - Nature Communications 2014 被引用: 193
- Parkinson’s disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures
著者: Mansoureh Hakimi, Thirumahal Selvanantham, Erika Swinton, Ruth Padmore, Youren Tong, Ghassan Kabbach, Kateřina Venderová, Stephen E. Girardin, Dennis E. Bulman, Clemens R. Scherzer, Matthew J. LaVoie, Denis Gris, David S. Park, Jonathan B. Angel, Jie Shen, Dana J. Philpott, Michael G. Schlossmacher - Journal of Neural Transmission 2011 被引用: 292
- Pathological Axonal Death through a MAPK Cascade that Triggers a Local Energy Deficit
著者: Jing Yang, Zhuhao Wu, Nicolas Renier, David Simon, Kunihiro Uryu, David S. Park, Peter A. Greer, Cathy Tournier, Roger J. Davis, Marc Tessier‐Lavigne - Cell 2015 被引用: 307
- Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites
著者: Jacqueline M. Tokarew, Daniel N. El-Kodsi, Nathalie A. Lengacher, Travis K. Fehr, Angela Nguyen, Bojan Shutinoski, Brian O’Nuallain, Ming Jin, Jasmine M. Khan, Andy Cheuk‐Him Ng, Juan Li, Qiubo Jiang, Mei Zhang, Liqun Wang, Rajib Sengupta, Kathryn R. Barber, An Tran, Doo Soon Im, Steve Callaghan, David S. Park, Stéphanie Zandee, Xiajun Dong, Clemens R. Scherzer, Alexandre Prat, Eve C. Tsai, Masashi Takanashi, Nobutaka Hattori, Jennifer A. Chan, Luigi Zecca, Andrew B. West, Arne Holmgren, Lawrence G. Puente, Gary S. Shaw, Gergely Tóth, John Woulfe, Peggy Taylor, Julianna J. Tomlinson, Michael G. Schlossmacher - Acta Neuropathologica 2021 被引用: 61
- Involvement of Interferon-γ in Microglial-Mediated Loss of Dopaminergic Neurons
著者: Matthew Mount, Arman Lira, David A. Grimes, Patrice D. Smith, Sylvie Faucher, Ruth S. Slack, Hymie Anisman, Shawn Hayley, David S. Park - Journal of Neuroscience 2007 被引用: 303
- Lrrk2 alleles modulate inflammation during microbial infection of mice in a sex-dependent manner
著者: Bojan Shutinoski, Mansoureh Hakimi, Irene E. Harmsen, Michaela Lunn, Juliana Dutra Barbosa da Rocha, Nathalie A. Lengacher, Yi Zhou, Jasmine M. Khan, Angela Nguyen, Quinton Hake-Volling, Daniel N. El-Kodsi, Juan Li, Azadeh Alikashani, Claudine Beauchamp, Jay Majithia, Kevin M. Coombs, Derya R. Shimshek, Paul C. Marcogliese, David S. Park, John D. Rioux, Dana J. Philpott, John Woulfe, Shawn Hayley, Subash Sad, Julianna J. Tomlinson, Earl G. Brown, Michael G. Schlossmacher - Science Translational Medicine 2019 被引用: 102
- Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy
著者: Maria Xilouri, Tereza Vogiatzi, Kostas Vekrellis, David S. Park, Leonidas Stefanis - PLoS ONE 2009 被引用: 347
- Programmed Cell Death in Parkinson's Disease
著者: Kateřina Venderová, David S. Park - Cold Spring Harbor Perspectives in Medicine 2012 被引用: 244
- Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson’s disease
著者: Kwang S. Kim, Paul C. Marcogliese, Jungwoo Yang, Steve Callaghan, Virgínia Maria Ferreira Resende, Elizabeth Abdel-Messih, Connie Marras, Naomi P. Visanji, Jana Huang, Michael G. Schlossmacher, Laura Trinkle‐Mulcahy, Ruth S. Slack, Anthony E. Lang, Canadian Lrrk2 in Inflammation Team (CLINT), David S. Park, Earl G. Brown, Derrick Gibbings, Shawn Hayley, David S. Park, Dana C. Philpott, John D. Rioux, Michael G. Schlossmacher, Erwin Schurr - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 被引用: 118
- PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress
著者: En Huang, Dianbo Qu, Tianwen Huang, Nicoletta Rizzi, Wassamon Boonying, Dorothy Krolak, Paolo Ciana, John Woulfe, Christine Klein, Ruth S. Slack, Daniel Figeys, David S. Park - Nature Communications 2017 被引用: 112
- Characteristics of the Ontario Neurodegenerative Disease Research Initiative cohort
著者: Kelly M. Sunderland, Derek Beaton, Stephen R. Arnott, Peter Kleinstiver, Donna Kwan, Jane M. Lawrence‐Dewar, Joel Ramirez, Brian Tan, Robert Bartha, Sandra E. Black, Michael Borrie, Donald C. Brien, Leanne K. Casaubon, Brian C. Coe, Benjamin Cornish, Allison A. Dilliott, Dar Dowlatshahi, Elizabeth Finger, Corinne E. Fischer, Andrew Frank, Julia Fraser, Morris Freedman, Barry Greenberg, David A. Grimes, Ayman Hassan, Wendy Hatch, Robert A. Hegele, Christopher Hudson, Mandar Jog, Sanjeev Kumar, Anthony E. Lang, Brian Levine, Wendy Lou, Jennifer Mandzia, Connie Marras, William E. McIlroy, Manuel Montero‐Odasso, David G. Munoz, Douglas P. Munoz, J. B. Orange, David S. Park, Stephen Pasternak, Frederico Pieruccini‐Faria, Tarek K. Rajji, Angela Roberts, John F. Robinson, Ekaterina Rogaeva, Demetrios J. Sahlas, Gustavo Saposnik, Christopher J.M. Scott, Dallas Seitz, Christen Shoesmith, Thomas Steeves, Michael J. Strong, Stephen C. Strother, Richard H. Swartz, Sean Symons, David F. Tang‐Wai, Maria Carmela Tartaglia, Angela K. Troyer, John Turnbull, Lorne Zinman, Paula McLaughlin, Mario Masellis, Malcolm A. Binns, the ONDRI Investigators - Alzheimer s & Dementia 2022 被引用: 31
- Cyclin-dependent kinases as a therapeutic target for stroke
著者: Hitoshi Osuga, Sachiko Osuga, Fuhu Wang, Raouf Fetni, Matthew J. Hogan, Ruth S. Slack, Antoine M. Hakim, Joh‐E Ikeda, David S. Park - National Academy of Sciences, Proceedings of the National Academy of Sciences 2000 被引用: 281
