James H. McKerrow
1970–2023 年に発表
- 154
- 論文数
- 21,707
- 被引用数
- 96
- h 指数
- 153
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Medicine46.7%
- Biochemistry, Genetics and Molecular Biology17.7%
- Immunology and Microbiology16.3%
- Computer Science7.3%
- Chemistry4.2%
- Environmental Science1.8%
- その他6%
トピック
- Parasites and Host Interactions5.5%
- Research on Leishmaniasis Studies5.3%
- Computational Drug Discovery Methods4.7%
- Trypanosoma species research and implications4.3%
- SARS-CoV-2 and COVID-19 Research3%
- Parasite Biology and Host Interactions2.8%
- その他74.4%
共著者
- Conor R. Caffrey22
- Elizabeth Hansell22
- Juan C. Engel16
- Jair L. Siqueira-Neto15
- Charles S. Craik14
- Mohammed Sajid14
- Patricia S. Doyle14
- Linda S. Brinen12
- Philip J. Rosenthal12
- Anthony J. O’Donoghue10
- Ivy Hsieh9
- Kee‐Chong Lim9
- Michelle R. Arkin8
- William Roush8
- Anjan Debnath7
- Fred E. Cohen7
- Judy A. Sakanari7
- Larissa M. Podust7
- Rafaela Salgado Ferreira7
- Danielle Skinner6
- Elany Barbosa da Silva6
- Jiří Gut6
- K. C. Lim6
- Ken Hirata6
全論文
- A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells
著者: Drake M. Mellott, Chien‐Te K. Tseng, Aleksandra Drelich, Pavla Fajtová, Balachandra Chenna, Demetrios H. Kostomiris, Jason Hsu, Jiyun Zhu, Zane W. Taylor, Klaudia I. Kocurek, Vivian Tat, Ardala Katzfuss, Linfeng Li, Miriam A. Giardini, Danielle Skinner, Ken Hirata, Michael C. Yoon, Sungjun Beck, Aaron F. Carlin, Alex E. Clark, Laura Beretta, Daniel C. Maneval, Vivian Hook, Felix W. Frueh, Brett L. Hurst, Hong Wang, Frank M. Raushel, Anthony J. O’Donoghue, Jair L. Siqueira-Neto, Thomas D. Meek, James H. McKerrow - ACS Chemical Biology 2021 被引用: 122
- IL-13 Activates a Mechanism of Tissue Fibrosis That Is Completely TGF-β Independent
著者: Mallika Kaviratne, Matthias Hesse, Mary Leusink, Allen W. Cheever, Stephen J. Davies, James H. McKerrow, Lalage M. Wakefield, John J. Letterio, Thomas A. Wynn - The Journal of Immunology 2004 被引用: 367
- Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase
著者: Laura‐Isobel McCall, Amale El Aroussi, Jun Yong Choi, Débora Vieira, Géraldine De Muylder, Jonathan B. Johnston, Steven Chen, Danielle Kellar, Jair L. Siqueira-Neto, William Roush, Larissa M. Podust, James H. McKerrow - PLoS neglected tropical diseases 2015 被引用: 122
- Phase I Clinical Trial Results of Auranofin, a Novel Antiparasitic Agent
著者: Edmund V. Capparelli, Robin Bricker-Ford, Michael J. Rogers, James H. McKerrow, Sharon L. Reed - Antimicrobial Agents and Chemotherapy 2016 被引用: 145
- Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L
著者: Anneliese S. Ashhurst, Arthur H. Tang, Pavla Fajtová, Michael C. Yoon, Anupriya Aggarwal, Max J. Bedding, Alexander Stoye, Laura Beretta, Dustin Pwee, Aleksandra Drelich, Danielle Skinner, Linfeng Li, Thomas D. Meek, James H. McKerrow, Vivian Hook, Chien‐Te K. Tseng, Mark Larance, Stuart Turville, William H. Gerwick, Anthony J. O’Donoghue, Richard J. Payne - Journal of Medicinal Chemistry 2021 被引用: 84
- Protease inhibitors targeting coronavirus and filovirus entry
著者: Yanchen Zhou, P. Vedantham, Kai Lü, Juliet Agudelo, Ricardo Carrion, Jerritt Nunneley, Dale L. Barnard, Stefan Pöhlmann, James H. McKerrow, Adam R. Renslo, Graham Simmons - Antiviral Research 2015 被引用: 626
- Cysteine proteases of parasitic organisms
著者: Mohammed Sajid, James H. McKerrow - Molecular and Biochemical Parasitology 2002 被引用: 796
- Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure–Activity Relationships, Antiviral Activity, and X-ray Structure Determination
著者: Thanigaimalai Pillaiyar, Philipp Flury, Nadine Krüger, Haixia Su, Laura Schäkel, Elany Barbosa da Silva, Olga Eppler, Thales Kronenberger, Tianqing Nie, Stephanie Luedtke, Cheila Rocha, Katharina Sylvester, Marvin Petry, James H. McKerrow, Antti Poso, Stefan Pöhlmann, Michael Gütschow, Anthony J. O’Donoghue, Yechun Xu, Christa E. Müller, Stefan Laufer - Journal of Medicinal Chemistry 2022 被引用: 67
- Complementarity Between a Docking and a High-Throughput Screen in Discovering New Cruzain Inhibitors
著者: Rafaela Salgado Ferreira, Anton Simeonov, Ajit Jadhav, O. Eidam, Bryan T. Mott, Michael J. Keiser, James H. McKerrow, David J. Maloney, John J. Irwin, Brian K. Shoichet - Journal of Medicinal Chemistry 2010 被引用: 245
- Global identification of peptidase specificity by multiplex substrate profiling
著者: Anthony J. O’Donoghue, A.A. Eroy-Reveles, Giselle M. Knudsen, Jessica R. Ingram, Min Zhou, Jacob B Statnekov, Alexander L. Greninger, Daniel R. Hostetter, Gang Qu, David Maltby, Marc O. Anderson, Joseph L. DeRisi, James H. McKerrow, Alma L. Burlingame, Charles S. Craik - Nature Methods 2012 被引用: 197
- Tropism of Dengue Virus in Mice and Humans Defined by Viral Nonstructural Protein 3-Specific Immunostaining
著者: Scott Balsitis, Joséfina Coloma, Glenda Castro, Aracely Alava, Diana Flores, James H. McKerrow, P. Robert Beatty, Eva Harris - American Journal of Tropical Medicine and Hygiene 2009 被引用: 251
- A Cysteine Protease Inhibitor Protects Dogs from Cardiac Damage during Infection byTrypanosoma cruzi
著者: Stephen C. Barr, Karen L. Warner, B. G. Kornreic, Janet Piscitelli, Alan R. Wolfe, Leslie Z. Benet, James H. McKerrow - Antimicrobial Agents and Chemotherapy 2005 被引用: 163
- Scaffold and Parasite Hopping: Discovery of New Protozoal Proliferation Inhibitors
著者: Baljinder Singh, Jean Bernatchez, Laura‐Isobel McCall, Cláudia M. Calvet, Jasmin Ackermann, Jorge Augusto Soares de Souza, Diane Thomas, Everton M. Silva, Kelly A. Bachovchin, Dana M. Klug, Hitesh B. Jalani, Seema Bag, Melissa J. Buskes, Susan E. Leed, Norma Roncal, Erica Penn, Jessey Erath, Ana Rodrı́guez, Richard J. Sciotti, Robert F. Campbell, James H. McKerrow, Jair L. Siqueira-Neto, Lori Ferrins, Michael P. Pollastri - ACS Medicinal Chemistry Letters 2020 被引用: 29
- Computer-aided design of 1,4-naphthoquinone-based inhibitors targeting cruzain and rhodesain cysteine proteases
著者: Leandro Rocha Silva, Ari Souza Guimarães, Jadiely do Nascimento, Igor José dos Santos Nascimento, Elany Barbosa da Silva, James H. McKerrow, Sílvia Helena Cardoso, Edeildo Ferreira da Silva‐Júnior - Bioorganic & Medicinal Chemistry 2021 被引用: 57
- Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole
著者: Cláudia M. Calvet, Tatiana Araújo Silva, Diane Thomas, Brian M. Suzuki, Ken Hirata, Jair L. Siqueira-Neto, James H. McKerrow - PLoS neglected tropical diseases 2020 被引用: 19
- Synthesis and Structure−Activity Relationship Study of Potent Trypanocidal Thio Semicarbazone Inhibitors of the Trypanosomal Cysteine Protease Cruzain
著者: Xiaohui Du, Chun Guo, Elizabeth Hansell, Patricia S. Doyle, Conor R. Caffrey, Tod P. Holler, James H. McKerrow, Fred E. Cohen - Journal of Medicinal Chemistry 2002 被引用: 383
- Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design
著者: Iain D. Kerr, Ji Hae Lee, Christopher J. Farady, Rachael Marion, Mathias Rickert, Mohammed Sajid, Kailash C. Pandey, Conor R. Caffrey, Jennifer Legac, Elizabeth Hansell, James H. McKerrow, Charles S. Craik, Philip Rosenthal, Linda S. Brinen - Journal of Biological Chemistry 2009 被引用: 297
- Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery
著者: Sean Ekins, Jair L. Siqueira-Neto, Laura‐Isobel McCall, Malabika Sarker, Maneesh K. Yadav, Elizabeth L. Ponder, E. Adam Kallel, Danielle Kellar, Steven Chen, Michelle R. Arkin, Barry A. Bunin, James H. McKerrow, Carolyn Talcott - PLoS neglected tropical diseases 2015 被引用: 96
- Herbal melanin inhibits colorectal cancer cell proliferation by altering redox balance, inducing apoptosis, and modulating MAPK signaling
著者: Omar Al‐Obeed, Adila El‐Obeid, Sabine Matou‐Nasri, Mansoor‐Ali Vaali‐Mohammed, Yazeid Alhaidan, Mohammed Elwatidy, Hamad Al Dosary, Zeyad Alehaideb, Khayal Al‐Khayal, Adil Haseeb, James H. McKerrow, Rehan Ahmad, Maha‐Hamadien Abdulla - Cancer Cell International 2020 被引用: 44
- Acanthamoeba Keratitis: an update on amebicidal and cysticidal drug screening methodologies and potential treatment with azole drugs
著者: Brian Shing, Mina Balen, James H. McKerrow, Anjan Debnath - Expert Review of Anti-infective Therapy 2021 被引用: 43
- Intramolecular Interactions Enhance the Potency of Gallinamide A Analogues against Trypanosoma cruzi
著者: Elany Barbosa da Silva, Vandna Sharma, Lilian Hernández Alvarez, Arthur H. Tang, Alexander Stoye, Anthony J. O’Donoghue, William H. Gerwick, Richard J. Payne, James H. McKerrow, Larissa M. Podust - Journal of Medicinal Chemistry 2022 被引用: 21
- Cysteine Protease Inhibitors Cure an Experimental Trypanosoma cruzi Infection
著者: Juan C. Engel, Patricia S. Doyle, Ivy Hsieh, James H. McKerrow - The Journal of Experimental Medicine 1998 被引用: 383
- A Screen against Leishmania Intracellular Amastigotes: Comparison to a Promastigote Screen and Identification of a Host Cell-Specific Hit
著者: Géraldine De Muylder, Kenny K. H. Ang, Steven Chen, Michelle R. Arkin, Juan C. Engel, James H. McKerrow - PLoS neglected tropical diseases 2011 被引用: 225
- Repurposing Auranofin as a Lead Candidate for Treatment of Lymphatic Filariasis and Onchocerciasis
著者: Christina A. Bulman, Chelsea M. Bidlow, Sara Lustigman, Fidelis Cho‐Ngwa, David L. Williams, Alberto A. Rascón, Nancy Tricoche, Moses Samje, Aaron Bell, Brian M. Suzuki, K. C. Lim, N. Supakorndej, P. Supakorndej, Alan R. Wolfe, Giselle M. Knudsen, Steven Chen, Chris Wilson, Kean-Hooi Ang, Michelle R. Arkin, Jiří Gut, Chris Franklin, Chris Marcellino, James H. McKerrow, Anjan Debnath, Judy A. Sakanari - PLoS neglected tropical diseases 2015 被引用: 110
