Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

著者: Aude Nicolas, Kevin P. Kenna, Alan E. Renton, Nicola Ticozzi, Faraz Faghri, Ruth Chia, Janice A. Dominov, Brendan Kenna, Mike A. Nalls, Pamela Keagle, Alberto Rivera, Wouter van Rheenen, Natalie A. Murphy, Joke J.F.A. van Vugt, Joshua T. Geiger, Rick A. A. van der Spek, Hannah A. Pliner, Shankaracharya, Bradley Smith, Giuseppe Marangi, Simon Topp, Yevgeniya Abramzon, Soragia Athina Gkazi, John D. Eicher, Aoife Kenna, Francesco O. Logullo, Isabella Laura Simone, Giancarlo Logroscino, Fabrizio Salvi, Ilaria Bartolomei, Giuseppe Borghero, Maria Rita Murru, Emanuela Costantino, Carla Pani, Roberta Puddu, Carla Caredda, Valeria Piras, Stefania Tranquilli, Stefania Cuccu, Daniela Corongiu, Maurizio Melis, Antonio Milia, Francesco Marrosu, Maria Giovanna Marrosu, Gianluca Floris, Antonino Cannas, Stefania Tranquilli, Margherita Capasso, Claudia Caponnetto, Gianluigi Mancardi, Paola Origone, Paola Mandich, F. L. Conforti, Sebastiano Cavallaro, Gabriele Mora, Kalliopi Marinou, Riccardo Sideri, Silvana Penco, Lorena Mosca, Christian Lunetta, Giuseppe Lauria Pinter, Massimo Corbo, Nilo Riva, Paola Carrera, Paolo Volanti, Jessica Mandrioli, Nicola Fini, Antonio Fasano, Lucio Tremolizzo, A Arosio, Carlo Ferrarese, Francesca Trojsi, Gioacchino Tedeschi, Maria Rosaria Monsurrò, Giovanni Piccirillo, Cinzia Femiano, Anna Ticca, Enzo Ortu, Vincenzo La Bella, Rossella Spataro, Tiziana Colletti, Mario Sabatelli, Marcella Zollino, Amelia Conte, Marco Luigetti, Serena Lattante, Giuseppe Marangi, Marialuisa Santarelli, Antonio Petrucci, Maura Pugliatti, Angelo Pirisi, Leslie D. Parish, Patrizia Occhineri, Fabio Giannini, Stefania Battistini, Claudia Ricci, Michele Benigni, Tea B. Cau, Daniela Loi, Andrea Calvo, Cristina Moglia, Maura Brunetti, Marco Barberis, Gabriella Restagno, Federico Casale, Giuseppe Marrali, Giuseppe Fuda, Irene Ossola, Stefania Cammarosano, Antonio Canosa, Antonio Ilardi, Umberto Manera, Maurizio Grassano, Raffaella Tanel, Fabrizio Pisano, Gabriele Mora, Andrea Calvo, Letizia Mazzini, Nilo Riva, Jessica Mandrioli, Claudia Caponnetto, Stefania Battistini, Paolo Volanti, Vincenzo La Bella, F. L. Conforti, Giuseppe Borghero, Sonia Messina, Isabella Laura Simone, Francesca Trojsi, Fabrizio Salvi, Francesco O. Logullo, Sandra D’Alfonso, Lucia Corrado, Margherita Capasso, Luigi Ferrucci, Matthew B. Harms, David B. Goldstein, Neil A. Shneider, Stephen A. Goutman, Zachary Simmons, Jonathan Mill, Siddharthan Chandran, Suvankar Pal, Georgios Manousakis, Stanley H. Appel, Ericka Simpson, Leo H. Wang, Robert H. Baloh, Summer Gibson, Richard Bedlack, David Lacomis, Dhruv Sareen, Alexander Sherman, Lucie Bruijn, Michelle A. Penny, Cristiane Araújo Martins Moreno, Sitharthan Kamalakaran, David B. Goldstein, Andrew S. Allen, Stanley H. Appel, Robert H. Baloh, Richard Bedlack, Braden Boone, Robert H. Brown, John P. Carulli, Alessandra Chesi, Wendy K. Chung, Elizabeth T. Cirulli, Gregory M. Cooper, Julien Couthouis, Kelly L. Williams, Patrick A. Dion, Summer Gibson, Aaron D. Gitler, Jonathan D. Glass, David B. Goldstein, Yujun Han, Matthew B. Harms, Tim Harris, Sebastian Hayes, Angela Jones, Jonathan Keebler, Brian J. Krueger, Brittany N. Lasseigne, Shawn Levy, Yifan Lu, Tom Maniatis, Diane McKenna-Yasek, Timothy M. Miller, R Myers, Slavé Petrovski, Stefan M. Pulst, Alya R. Raphael, John M. Ravits, Zhong Ren, Guy A. Rouleau, Peter C. Sapp, Neil A. Shneider, Ericka Simpson, Katherine B. Sims, John F. Staropoli, Lindsay L. Waite, Quanli Wang, Jack R. Wimbish, Winnie Xin, Aaron D. Gitler, Tim Harris, R Myers, Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono, Edward B. Lee, Vivianna M. Van Deerlin, Neil A. Shneider, Ernest Fraenkel, Lyle W. Ostrow, Frank Baas, Noah Zaitlen, James D. Berry, Andrea Malaspina, Pietro Fratta, Gregory A. Cox, Leslie M. Thompson, Steven Finkbeiner, Efthimios Dardiotis, Jonathan Mill, Siddharthan Chandran, Suvankar Pal, Eran Hornstein, Daniel J. MacGowan, Terry Heiman‐Patterson, Molly Hammell, Nikolaos A. Patsopoulos, Josh Dubnau, Avindra Nath, Hemali Phatnani, Rajeeva Musunuri, Uday S. Evani, Avinash Abhyankar, Michael C. Zody, Julia Kaye, Steven Finkbeiner, Stacia K. Wyman, Alexander LeNail, Leandro de Araújo Lima, Ernest Fraenkel, Jeffrey D. Rothstein, Clive N. Svendsen, Leslie M. Thompson, Jenny Van Eyk, Nicholas J. Maragakis, James D. Berry, Jonathan D. Glass, Jonathan Mill, Stephen J. Kolb, Robert H. Baloh, Merit Cudkowicz, Emily G. Baxi, Julia Kaye, Steven Finkbeiner, Stacia K. Wyman, Alex Lenail, Leandro de Araújo Lima, Ernest Fraenkel, Clive N. Svendsen, Leslie M. Thompson, Jennifer E. Van Eyk, James D. Berry, Timothy M. Miller, Stephen J. Kolb, Merit Cudkowicz, Emily G. Baxi, Michael Benatar, J. Paul Taylor, Gang Wu, Evadnie Rampersaud, Joanne Wuu, Rosa Rademakers, Stephan Züchner, Rebecca Schüle, Jacob L. McCauley, Sumaira Hussain, Anne Cooley, Marielle Wallace, Christine Clayman, Richard J. Barohn, Jeffrey Statland, John Ravits, Andrea Swenson, Carlayne E. Jackson, Jaya Trivedi, Shaida Khan, Jonathan Katz, Liberty Jenkins, Ted M. Burns, Kelly Gwathmey, James B. Caress, Corey T. McMillan, Lauren Elman, Erik P. Pioro, Jeannine M. Heckmann, Yuen T. So, David Walk, Samuel Maiser, Jinghui Zhang, Michael Benatar, J. Paul Taylor, Evadnie Rampersaud, Gang Wu, Joanne Wuu, Vincenzo Silani, Nicola Ticozzi, Cinzia Gellera, Antonia Ratti, Franco Taroni, Giuseppe Lauria, Federico Verde, Isabella Fogh, Cinzia Tiloca, Giacomo P. Comi, Gianni Sorarú, Cristina Cereda, Sandra D’Alfonso, Lucia Corrado, Fabiola De Marchi, Stefania Corti, Mauro Ceroni, Letizia Mazzini, Gabriele Siciliano, Massimiliano Filosto, Maurizio Inghilleri, Silvia Peverelli, Claudia Colombrita, Barbara Poletti, Luca Maderna, Roberto Del Bo, Stella Gagliardi, Giorgia Querin, Cinzia Bertolin, Viviana Pensato, Barbara Castellotti, Giuseppe Lauria, Federico Verde, Isabella Fogh, Cinzia Tiloca, Giacomo P. Comi, Gianni Sorarú, Cristina Cereda, William Camu, Kevin Mouzat, Serge Lumbroso, Philippe Corcia, Vincent Meininger, Gérard Besson, Emmeline Lagrange, Pierre Clavelou, Nathalie Guy, Philippe Couratier, Patrick Vourc’h, Véronique Danel, E Bernard, Gwendal Le Masson, Philippe Corcia, Hannu Laaksovirta, Liisa Myllykangas, Lilja Jansson, Miko Valori, John Ealing, Hisham Hamdalla, Sara Rollinson, Stuart Pickering‐Brown, Richard W. Orrell, Katie Sidle, Andrea Malaspina, John Hardy, Andrew Singleton, Janel O. Johnson, Sampath Arepalli, Peter C. Sapp, Diane McKenna-Yasek, Meraida Polak, Seneshaw Asress, Safa Al‐Sarraj, Andrew King, Claire Troakes, Caroline Vance, Jacqueline de Belleroche, Frank Baas, Anneloor L.M.A. ten Asbroek, José Luís Muñoz-Blanco, Dena G. Hernandez, Jinhui Ding, J. Raphael Gibbs, Sonja W. Scholz, Mary Kay Floeter, Roy H. Campbell, Francesco Landi, Robert Bowser, Stefan M. Pulst, John M. Ravits, Daniel J. MacGowan, Janine Kirby, Erik P. Pioro, Roger Pamphlett, James R. Broach, Glenn S. Gerhard, Travis Dunckley, Christopher B. Brady, Neil W. Kowall, Juan C. Troncoso, Isabelle Le Ber, Kevin Mouzat, Serge Lumbroso, Terry Heiman‐Patterson, Freya Kamel, Ludo Van Den Bosch, Robert H. Baloh, Tim M. Strom, Thomas Meitinger, Aleksey Shatunov, Kristel R. van Eijk, Mamede de Carvalho, Maarten Kooyman, Bas Middelkoop, Matthieu Moisse, Russell L. McLaughlin, Michael A. van Es, Markus Weber, Khrista Boylan, Marka van Blitterswijk, Rosa Rademakers, Karen Morrison, A. Nazli Basak, Jesús S. Mora, Vivian E. Drory, Pamela J. Shaw, Martin R. Turner, Kevin Talbot, Orla Hardiman, Kelly L. Williams, Jennifer A. Fifita, Garth A. Nicholson, Ian P. Blair, Guy A. Rouleau, Jesús Esteban‐Pérez, Alberto García‐Redondo, Ammar Al-Chalabi, Ahmad Al Kheifat, Ammar Al-Chalabi, Peter M. Andersen, A. Nazli Basak, Ian P. Blair, Adriano Chiò, Johnathan Cooper‐Knock, Philippe Corcia, Philippe Couratier, Mamede de Carvalho, Annelot Dekker, Vivian E. Drory, Alberto García‐Redondo, Marc Gotkine, Orla Hardiman, Winston Hide, Alfredo Iacoangeli, Jonathan D. Glass, Kevin Kenna, Matthew C. Kiernan, Maarten Kooyman, John Landers, Russell L. McLaughlin, Bas Middelkoop, Jonathan Mill, Miguel Mitne‐Neto, Mattieu Moisse, Jesús Mora Pardina, Karen Morrison, Stephen Newhouse, Susana Pinto, Sara L. Pulit, Wim Robberecht, Aleksey Shatunov, Pamela Shaw, Christopher E. Shaw, Vincenzo Silani, William Sproviero, Gijs Tazelaar, Nicola Ticozzi, Michael A. van Es, Leonard van den Berg, Rick A. A. van der Spek, Kristel van Eijk, Michael A. van Es, Wouter van Rheenen, Joke J.F.A. van Vugt, Jan H. Veldink, Markus Weber, Kelly L. Williams, Mayana Zatz, Denis C. Bauer, Natalie A. Twine, Ekaterina Rogaeva, Lorne Zinman, Lyle W. Ostrow, Nicholas J. Maragakis, Jeffrey D. Rothstein, Zachary Simmons, Johnathan Cooper‐Knock, Alexis Brice, Stephen A. Goutman, Eva L. Feldman, Summer Gibson, Franco Taroni, Antonia Ratti, Cinzia Gellera, Michael A. van Es, Wim Robberecht, Pietro Fratta, Mario Sabatelli, Christian Lunetta, Albert C. Ludolph, Peter M. Andersen, Jochen H. Weishaupt, William Camu, John Q. Trojanowski, Vivianna M. Van Deerlin, Robert H. Brown, Leonard H. van den Berg, Jan H. Veldink, Matthew B. Harms, Jonathan D. Glass, David J. Stone, Pentti J. Tienari, Vincenzo Silani, Adriano Chiò, Christopher E. Shaw, Bryan J. Traynor, John E. Landers - Neuron 2018 被引用: 718