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Christoph Klein

Active 1993–2025

220
Papers
41,623
Citations
103
h-index
205
i10-index

Citations

Citations per year for Christoph Klein1977: 1 citations1983: 1 citations1988: 1 citations1991: 2 citations1993: 1 citations1996: 5 citations1997: 6 citations1998: 8 citations1999: 8 citations2000: 28 citations2001: 45 citations2002: 62 citations2003: 62 citations2004: 113 citations2005: 89 citations2006: 98 citations2007: 133 citations2008: 128 citations2009: 118 citations2010: 143 citations2011: 178 citations2012: 247 citations2013: 306 citations2014: 404 citations2015: 375 citations2016: 366 citations2017: 395 citations2018: 400 citations2019: 1,169 citations2020: 1,413 citations2021: 1,651 citations2022: 1,509 citations2023: 1,067 citations2024: 1,611 citations2025: 791 citations2026: 48 citations1978–1982: no citations, so these years are not shown1984–1987: no citations, so these years are not shown1989–1990: no citations, so these years are not shown1992: no citations, so this year is not shown1994–1995: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 4,435 citing papers, 23% of this breakdownGermany: 1,636 citing papers, 8.5% of this breakdownUnited Kingdom: 1,619 citing papers, 8.4% of this breakdownChina: 1,133 citing papers, 5.9% of this breakdownFrance: 966 citing papers, 5% of this breakdownItaly: 809 citing papers, 4.2% of this breakdownCanada: 682 citing papers, 3.5% of this breakdownNetherlands: 639 citing papers, 3.3% of this breakdownAustralia: 539 citing papers, 2.8% of this breakdownSpain: 503 citing papers, 2.6% of this breakdownJapan: 480 citing papers, 2.5% of this breakdownSwitzerland: 449 citing papers, 2.3% of this breakdown
0%23%Other 28%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology32.5%
  • Medicine31.2%
  • Immunology and Microbiology22.8%
  • Neuroscience3.7%
  • Computer Science2.6%
  • Dentistry1.3%
  • Other5.9%

Topics

  • Immunodeficiency and Autoimmune Disorders5.2%
  • Immune Cell Function and Interaction3%
  • Protein Structure and Dynamics2.3%
  • Blood disorders and treatments1.9%
  • T-cell and B-cell Immunology1.9%
  • COVID-19 Clinical Research Studies1.8%
  • Other83.9%

Coauthors

All papers

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  1. MDTraj: A Modern Open Library for the Analysis of Molecular Dynamics Trajectories

    Authors: Robert T. McGibbon, Kyle A. Beauchamp, Matthew P. Harrigan, Christoph Klein, Jason Swails, Carlos X. Hernández, Christian R. Schwantes, Lee‐Ping Wang, Thomas J. Lane, Vijay S. Pande - Biophysical Journal 2015 cited by 2,570

  2. The Human Phenotype Ontology in 2021

    Authors: Sebastian Köhler, Michael A. Gargano, Nicolas Matentzoglu, Leigh Carmody, David Lewis-Smith, Nicole A. Vasilevsky, Daniel Danis, Ganna Balagura, Gareth Baynam, Amy M. Brower, Tiffany J. Callahan, Christopher G. Chute, Johanna L. Est, Peter D. Galer, Shiva Ganesan, Matthias Griese, Matthias Haimel, Julia Pazmandi, Marc Hanauer, Nomi L. Harris, Michael Hartnett, Maximilian Hastreiter, Fabian Hauck, Yongqun He, Tim Jeske, Hugh Kearney, Gerhard Kindle, Christoph Klein, Katrin Knoflach, Roland Krause, David Lagorce, Julie A. McMurry, Jillian A. Miller, Monica C. Munoz-Torres, Rebecca L. Peters, Christina K. Rapp, Ana Rath, Shahmir A. Rind, Avi Z. Rosenberg, Michael M. Segal, Markus G. Seidel, Damian Smedley, Tomer Talmy, Yarlalu Thomas, Samuel A. Wiafe, Julie Xian, Zafer Yüksel, Ingo Helbig, Christopher J. Mungall, Melissa A. Haendel, Peter N. Robinson - Nucleic Acids Research, Nucleic Acids Res. 2020 cited by 1,240

  3. Human Inborn Errors of Immunity: 2022 Update on the Classification from the International Union of Immunological Societies Expert Committee

    Authors: Stuart G. Tangye, Waleed Al–Herz, Aziz Bousfiha, Charlotte Cunningham‐Rundles, José Luis Franco, Steven M. Holland, Christoph Klein, Tomohiro Morio, Éric Oksenhendler, Capucine Pïcard, Anne Puel, Jennifer M. Puck, Mikko Seppänen, Raz Somech, Helen C. Su, Kathleen E. Sullivan, Troy R. Torgerson, Isabelle Meyts - Journal of Clinical Immunology 2022 cited by 1,144

  4. Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment

    Authors: Jonas Schulte-Schrepping, Nico Reusch, Daniela Paclik, Kevin Baßler, Stephan Schlickeiser, Bowen Zhang, Benjamin Krämer, Tobias Krammer, Sophia Brumhard, Lorenzo Bonaguro, Elena De Domenico, Daniel Wendisch, Martin Graßhoff, Theodore S. Kapellos, Michael Beckstette, Tal Pecht, Adem Saglam, Oliver Dietrich, Henrik E. Mei, Axel Schulz, Claudia Conrad, Désirée Kunkel, Ehsan Vafadarnejad, Cheng‐Jian Xu, Arik Horne, Miriam Herbert, Anna Drews, Charlotte Thibeault, Moritz Pfeiffer, Stefan Hippenstiel, Andreas C. Hocke, Holger Müller-Redetzky, Kathrin Heim, Felix Machleidt, Alexander Uhrig, Laure Bosquillon de Jarcy, Linda Jürgens, Miriam Stegemann, Christoph R. Glösenkamp, Hans‐Dieter Volk, Christine Goffinet, Markus Landthaler, Emanuel Wyler, Philipp Georg, Maria Schneider, Chantip Dang‐Heine, Nick Neuwinger, Kai Kappert, R Tauber, Victor M. Corman, Jan Raabe, Kim M Kaiser, M To Vinh, Gereon Rieke, Christian Meisel, Thomas Ulas, Matthias Becker, Robert Geffers, Martin Witzenrath, Christian Drosten, Norbert Suttorp, Christof von Kalle, Florian Kurth, Kristian Händler, Joachim L. Schultze, Anna C. Aschenbrenner, Yang Li, Jacob Nattermann, Birgit Sawitzki, Antoine‐Emmanuel Saliba, Leif Erik Sander, Angel Angelov, Robert Bals, Alexander Bartholomäus, Anke Becker, Daniela Bezdan, Ezio Bonifacio, Peer Bork, Thomas Clavel, Maria Colomé‐Tatché, Andreas Diefenbach, Alexander Dilthey, Nicole Fischer, Konrad U. Förstner, Julia-Stefanie Frick, Julien Gagneur, Alexander Goesmann, Torsten Hain, Michael Hummel, Stefan Janssen, Jörn Kalinowski, René Kallies, Birte Kehr, Andreas Keller, Sarah Kim-Hellmuth, Christoph Klein, Oliver Kohlbacher, Jan O. Korbel, Ingo Kurth, Markus Landthaler and 40 more - Cell 2020 cited by 1,628

  5. The 2022 Update of IUIS Phenotypical Classification for Human Inborn Errors of Immunity

    Authors: Aziz Bousfiha, Abderrahmane Moundir, Stuart G. Tangye, Capucine Pïcard, Leïla Jeddane, Waleed Al–Herz, Charlotte Cunningham Rundles, José Luis Franco, Steven M. Holland, Christoph Klein, Tomohiro Morio, Éric Oksenhendler, Anne Puel, Jennifer M. Puck, Mikko Seppänen, Raz Somech, Helen C. Su, Kathleen E. Sullivan, Troy R. Torgerson, Isabelle Meyts - Journal of Clinical Immunology 2022 cited by 492

  6. Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation

    Authors: Gui‐Wei He, Lin Lin, Jeff DeMartino, Xuan Zheng, Nadzeya Staliarova, Talya L. Dayton, Harry Begthel, Willine J. van de Wetering, Eduard Bodewes, Jeroen S. van Zon, Sander J. Tans, Carmen Lopez-Iglesias, Peter J. Peters, Wei Wu, Daniel Kotlarz, Christoph Klein, Thanasis Margaritis, Frank C. P. Holstege, Hans Clevers - Cell stem cell 2022 cited by 173

  7. Lessons learned from comparing molecular dynamics engines on the SAMPL5 dataset

    Authors: Michael R. Shirts, Christoph Klein, Jason M. Swails, Jian Yin, Michael K. Gilson, David L. Mobley, David A. Case, Ellen D. Zhong - Journal of Computer-Aided Molecular Design, J. Comput. Aided Mol. Des. 2016 cited by 394

  8. Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

    Authors: Dror S. Shouval, Amlan Biswas, Jeremy A. Goettel, Katelyn McCann, Evan Conaway, Naresh Singh Redhu, Iván Mascanfroni, Ziad Al Adham, Sydney Lavoie, Mouna Ibourk, Deanna D. Nguyen, Janneke N. Samsom, Johanna C. Escher, Raz Somech, Batia Weiss, Rita Beier, Laurie S. Conklin, Christen L. Ebens, Fernanda Gontijo Minafra Silveira Santos, Alexandre R. Ferreira, Mary Sherlock, Atul K. Bhan, Werner Müller, J. Rodrigo Mora, Francisco J. Quintana, Christoph Klein, Aleixo M. Muise, Bruce Horwitz, Scott B. Snapper - Immunity 2014 cited by 579

  9. Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee

    Authors: Stuart G. Tangye, Waleed Al–Herz, Aziz Bousfiha, Talal A. Chatila, Charlotte Cunningham‐Rundles, Amos Etzioni, José Luis Franco, Steven M. Holland, Christoph Klein, Tomohiro Morio, Hans D. Ochs, Éric Oksenhendler, Capucine Pïcard, Jennifer M. Puck, Troy R. Torgerson, Jean‐Laurent Casanova, Kathleen E. Sullivan - Journal of Clinical Immunology 2020 cited by 1,224

  10. The European Society for Immunodeficiencies (ESID) Registry Working Definitions for the Clinical Diagnosis of Inborn Errors of Immunity

    Authors: Markus G. Seidel, Gerhard Kindle, Benjamin Gathmann, Isabella Quinti, Matthew Buckland, Joris van Montfrans, Raphael Scheible, Stephan Rusch, Lukas Gasteiger, Bodo Grimbacher, Nizar Mahlaoui, Stephan Ehl, Mario Abinun, Michael H. Albert, Sarah Beaussant-Cohen, Jacinta Bustamante, Andrew J. Cant, Jean‐Laurent Casanova, Helen Chapel, Geneviève de Saint Basile, Esther de Vries, Inderjeet Dokal, Jean Donadieu, Anne Durandy, David Edgar, Teresa Español, Amos Etzioni, Alain Fischer, Bobby Gaspar, Richard A. Gatti, Andrew R. Gennery, Sofia Grigoriadou, Steven M. Holland, Gritta Janka, Maria Kanariou, Christoph Klein, Helen J. Lachmann, Desa Lilić, Ania Manson, N. Pascual Martínez, Isabelle Meyts, Nicolette Moes, Despina Moshous, Bénédicte Neven, Hans D. Ochs, Capucine Pïcard, Ellen D. Renner, Frédéric Rieux‐Laucat, Reinhard Seger, Annarosa Soresina, Dominique Stoppa‐Lyonnet, Vojtěch Thon, Adrian J. Thrasher, Frank L. van de Veerdonk, Anna Villa, Corry M.R. Weemaes, Klaus Warnatz, Beata M. Wolska, Shen-Yin Zhang - The Journal of Allergy and Clinical Immunology In Practice 2019 cited by 621

  11. Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

    Authors: Erik‐Oliver Glocker, Daniel Kotlarz, Kaan Boztuǧ, E. Michael Gertz, Alejandro A. Schäffer, Fatih Noyan, Mario Perro, Jana Diestelhorst, Anna Allroth, Dhaarini Murugan, Nadine Hätscher, Dietmar Pfeifer, Karl‐Walter Sykora, Martin G. Sauer, Hans Kreipe, Martin Lacher, R. Nustede, Cristina Woellner, Ulrich Baumann, Ulrich Salzer, Sibylle Koletzko, Neil Shah, Anthony W. Segal, Axel Sauerbrey, Stephan Buderus, Scott B. Snapper, Bodo Grimbacher, Christoph Klein - New England Journal of Medicine 2009 cited by 1,426

  12. Generation of complex bone marrow organoids from human induced pluripotent stem cells

    Authors: Stephanie Frenz-Wiessner, Savannah Fairley, Maximilian Buser, Isabel Goek, Kirill Salewskij, Gustav Jonsson, David W. Illig, Benedicta zu Putlitz, Daniel Petersheim, Yue Li, Pin‐Hsuan Chen, Martina Kalauz, Raffaele Conca, Michael Sterr, Johanna Geuder, Yoko Mizoguchi, Remco T. A. Megens, Monika I. Linder, Daniel Kotlarz, Martina Rudelius, Josef Penninger, Carsten Marr, Christoph Klein - Nature Methods 2024 cited by 129

  13. OpenMM 4: A Reusable, Extensible, Hardware Independent Library for High Performance Molecular Simulation

    Authors: Peter Eastman, Mark S. Friedrichs, John D. Chodera, Randall J. Radmer, Christopher M. Bruns, Joy P. Ku, Kyle A. Beauchamp, Thomas J. Lane, Lee‐Ping Wang, Diwakar Shukla, Tony Tye, Mike Houston, Timo Stich, Christoph Klein, Michael R. Shirts, Vijay S. Pande - Journal of Chemical Theory and Computation 2012 cited by 750

  14. Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19

    Authors: Benjamin Krämer, Rainer Knoll, Lorenzo Bonaguro, Michael ToVinh, Jan Raabe, Rosario Astaburuaga-García, Jonas Schulte-Schrepping, Kim M Kaiser, Gereon Rieke, Jenny Bischoff, Malte B. Monin, Christoph Hoffmeister, Stefan Schlabe, Elena De Domenico, Nico Reusch, Kristian Händler, Gary Reynolds, Nils Blüthgen, Gudrun Hack, Claudia Finnemann, Hans Dieter Nischalke, Christian P. Strassburg, Emily Stephenson, Yapeng Su, Louis Gardner, Dan Yuan, Daniel Chen, Jason D. Goldman, Philip Rosenstiel, Susanne V. Schmidt, Eicke Latz, Kevin Hrusovsky, Andrew J. Ball, Joe M. Johnson, Paul-Albert Koenig, Florian I. Schmidt, Muzlifah Haniffa, James R. Heath, Beate M. Kümmerer, Verena Keitel, Björn Jensen, Paula Stubbemann, Florian Kurth, Leif Erik Sander, Birgit Sawitzki, Janine Altmüller, Angel Angelov, Anna C. Aschenbrenner, Robert Bals, Alexander Bartholomäus, Anke Becker, Matthias Becker, Daniela Bezdan, Michael Bitzer, Conny Blumert, Ezio Bonifacio, Peer Bork, Boyke Bunk, Helmut Blum, Nicolas Casadei, Thomas Clavel, Maria Colomé‐Tatché, Markus Cornberg, Inti Alberto De La Rosa Velázquez, Andreas Diefenbach, Alexander Dilthey, Nicole Fischer, Konrad U. Förstner, Sören Franzenburg, Julia-Stefanie Frick, Gisela Gabernet, Julien Gagneur, Tina Ganzenmueller, Marie Gauder, Janina Geißert, Alexander Goesmann, Siri Göpel, Adam Grundhoff, Hajo Grundmann, Torsten Hain, Frank Hanses, Ute Hehr, André Heimbach, Marius M. Hoeper, Friedemann Horn, Daniel Hübschmann, Michael Hummel, Thomas Iftner, Angelika Iftner, Thomas Illig, Stefan Janssen, Jörn Kalinowski, René Kallies, Birte Kehr, Andreas Keller, Oliver T. Keppler, Sarah Kim-Hellmuth, Christoph Klein, Michael Knop, Oliver Kohlbacher and 63 more - Immunity 2021 cited by 257

  15. Gene Therapy for Wiskott-Aldrich Syndrome—Long-Term Efficacy and Genotoxicity

    Authors: Christian Braun, Kaan Boztuǧ, Anna Paruzynski, Maximilian Witzel, Adrian Schwarzer, Michael Rothe, Ute Modlich, Rita Beier, Gudrun Göhring, Doris Steinemann, Raffaele Fronza, Claudia R. Ball, Reinhard Haemmerle, Sonja Naundorf, Klaus Kühlcke, Martina Rose, Chris Fraser, Liesl Mathias, Rudolf Ferrari, Miguel R. Abboud, Waleed Al–Herz, Irina Kondratenko, László Maródi, Hanno Glimm, Brigitte Schlegelberger, Axel Schambach, Michael H. Albert, Manfred Schmidt, Christof von Kalle, Christoph Klein - Science Translational Medicine 2014 cited by 555

  16. Disrupted degradative sorting of TLR7 is associated with human lupus

    Authors: Harshita Mishra, Claire Schlack-Leigers, Ee Lyn Lim, Oliver Thieck, Thomas Magg, Johannes Raedler, Christine Wolf, Christoph Klein, Helge Ewers, Min Ae Lee‐Kirsch, David Meierhofer, Fabian Hauck, Olivia Majer - Science Immunology 2024 cited by 63

  17. Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

    Authors: Alexandra Y. Kreins, Michael J. Ciancanelli, Satoshi Okada, Xiao‐Fei Kong, Noé Ramirez‐Alejo, Sara Şebnem Kılıç, Jamila El Baghdadi, Shigeaki Nonoyama, Seyed Alireza Mahdaviani, Fatima Ailal, Aziz Bousfiha, Davood Mansouri, Elma Nievas, S. Cindy, Geetha Rao, Andrea Bernasconi, Hye Sun Kuehn, Julie E. Niemela, Jennifer Stoddard, Paul Deveau, Aurélie Cobat, Safa El Azbaoui, Ayoub Sabri, Che Kang Lim, Mikael Sundin, Danielle T. Avery, Rabih Halwani, Audrey V. Grant, Bertrand Boisson, Dusan Bogunovic, Yuval Itan, Marcela Moncada‐Vélez, Rubén Martínez‐Barricarte, Mélanie Migaud, Caroline Deswarte, Laia Alsina, Daniel Kotlarz, Christoph Klein, Ingrid Müller‐Fleckenstein, Bernhard Fleckenstein, Valérie Cormier‐Daire, Stefan Rose‐John, Capucine Pïcard, Lennart Hammarström, Anne Puel, Saleh Al‐Muhsen, Laurent Abel, Damien Chaussabel, Sergio D. Rosenzweig, Yoshiyuki Minegishi, Stuart G. Tangye, Jacinta Bustamante, Jean‐Laurent Casanova, Stéphanie Boisson‐Dupuis - The Journal of Experimental Medicine 2015 cited by 356

  18. Democratizing knowledge representation with BioCypher

    Authors: Sebastian Lobentanzer, Patrick Aloy, Jan Baumbach, Balázs Bohár, Vincent J. Carey, Pornpimol Charoentong, Katharina Danhauser, Tunca Doğan, Johann Dréo, Ian Dunham, Elias Farr, Adrià Fernandez-Torras, Benjamin M. Gyori, Michael Hartung, Charles Tapley Hoyt, Christoph Klein, Tamás Korcsmáros, Andreas Maier, Matthias Mann, David Ochoa, Elena Pareja-Lorente, Ferdinand Popp, Martin Preusse, Niklas Probul, Benno Schwikowski, Bünyamin Şen, Maximilian T. Strauss, Dénes Türei, Erva Ulusoy, Dagmar Waltemath, Judith A. H. Wodke, Julio Sáez-Rodríguez - Nature Biotechnology 2023 cited by 65

  19. The Diagnostic Approach to Monogenic Very Early Onset Inflammatory Bowel Disease

    Authors: Holm H. Uhlig, Tobias Schwerd, Sibylle Koletzko, Neil Shah, Jochen Kammermeier, Abdul Elkadri, Jodie Ouahed, David C. Wilson, Simon Travis, Dan Turner, Christoph Klein, Scott B. Snapper, Aleixo M. Muise - Gastroenterology 2014 cited by 726

  20. Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies

    Authors: Jodie Ouahed, Elizabeth A. Spencer, Daniel Kotlarz, Dror S. Shouval, Matthew Kowalik, Kaiyue Peng, Michael Field, Leslie Grushkin-Lerner, Sung‐Yun Pai, Athos Bousvaros, Judy H. Cho, Carmen Argmann, Eric E. Schadt, Dermot McGovern, Michal Mokrý, Edward E. S. Nieuwenhuis, Hans Clevers, Fiona Powrie, Holm H. Uhlig, Christoph Klein, Aleixo M. Muise, Marla C. Dubinsky, Scott B. Snapper - Inflammatory Bowel Diseases 2019 cited by 222

  21. Gain-of-function IKZF1 variants in humans cause immune dysregulation associated with abnormal T/B cell late differentiation

    Authors: Akihiro Hoshino, David Boutboul, Yuan Zhang, Hye Sun Kuehn, Jérôme Hadjadj, Nihal Özdemir, Tiraje Çelkan, Christoph Walz, Capucine Pïcard, Christelle Lenoir, Nizar Mahlaoui, Christoph Klein, Xiao Peng, Antoine Azar, Erin L. Reigh, Morgane Cheminant, Alain Fischer, Frédéric Rieux‐Laucat, Isabelle Callebaut, Fabian Hauck, Joshua D. Milner, Sergio D. Rosenzweig, Sylvain Latour - Science Immunology 2022 cited by 80

  22. Interleukin 10 Receptor Signaling

    Authors: Dror S. Shouval, Jodie Ouahed, Amlan Biswas, Jeremy A. Goettel, Bruce Horwitz, Christoph Klein, Aleixo M. Muise, Scott B. Snapper - Advances in immunology 2014 cited by 303

  23. Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases

    Authors: Yue Li, Marita Führer, Ehsan Bahrami, Piotr Socha, Maja Klaudel‐Dreszler, A. Bouzidi, Yanshan Liu, Anna S. Lehle, Thomas Magg, Sebastian Hollizeck, Meino Rohlfs, Raffaele Conca, Michael Field, Neil Warner, Mordechai Slae, Eyal Shteyer, Dan Turner, Rachida Boukari, Reda Belbouab, Christoph Walz, Moritz M. Gaidt, Veit Hornung, Bernd Baumann, Ulrich Pannicke, Eman Al Idrissi, Hamza AlGhamdi, Fernando E. Sepulveda, Marine Gil, Geneviève de Saint Basile, Manfred Hönig, Sibylle Koletzko, Aleixo M. Muise, Scott B. Snapper, Klaus Schwarz, Christoph Klein, Daniel Kotlarz - National Academy of Sciences, Proceedings of the National Academy of Sciences 2018 cited by 193

  24. Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification

    Authors: Aziz Bousfiha, Leïla Jeddane, Capucine Pïcard, Waleed Al–Herz, Fatima Ailal, Talal A. Chatila, Charlotte Cunningham‐Rundles, Amos Etzioni, José Luis Franco, Steven M. Holland, Christoph Klein, Tomohiro Morio, Hans D. Ochs, Éric Oksenhendler, Jennifer M. Puck, Troy R. Torgerson, Jean‐Laurent Casanova, Kathleen E. Sullivan, Stuart G. Tangye - Journal of Clinical Immunology 2020 cited by 691