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Harry Begthel

Active 2003–2025

63
Papers
30,319
Citations
51
h-index
61
i10-index

Citations

Citations per year for Harry Begthel1992: 1 citations1994: 2 citations1996: 2 citations2003: 4 citations2004: 37 citations2005: 85 citations2006: 134 citations2007: 142 citations2008: 218 citations2009: 236 citations2010: 314 citations2011: 414 citations2012: 413 citations2013: 328 citations2014: 393 citations2015: 379 citations2016: 364 citations2017: 438 citations2018: 483 citations2019: 1,064 citations2020: 1,543 citations2021: 1,621 citations2022: 1,271 citations2023: 1,059 citations2024: 1,504 citations2025: 803 citations2026: 23 citations1993: no citations, so this year is not shown1995: no citations, so this year is not shown1997–2002: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,565 citing papers, 27% of this breakdownChina: 1,739 citing papers, 13.2% of this breakdownUnited Kingdom: 970 citing papers, 7.3% of this breakdownNetherlands: 923 citing papers, 7% of this breakdownGermany: 800 citing papers, 6.1% of this breakdownJapan: 572 citing papers, 4.3% of this breakdownItaly: 404 citing papers, 3.1% of this breakdownFrance: 395 citing papers, 3% of this breakdownSwitzerland: 337 citing papers, 2.5% of this breakdownCanada: 314 citing papers, 2.4% of this breakdownSpain: 289 citing papers, 2.2% of this breakdownAustralia: 272 citing papers, 2.1% of this breakdown
0%27%Other 19.8%

Institutions

Fields

  • Medicine49.5%
  • Biochemistry, Genetics and Molecular Biology36.2%
  • Engineering4.7%
  • Immunology and Microbiology4%
  • Neuroscience2.2%
  • Nursing1.3%
  • Other2.1%

Topics

  • Cancer Cells and Metastasis11.7%
  • 3D Printing in Biomedical Research3.8%
  • Wnt/β-catenin signaling in development and cancer3.2%
  • Epigenetics and DNA Methylation2.7%
  • Cancer Genomics and Diagnostics2.6%
  • Digestive system and related health2.6%
  • Other73.4%

Coauthors

All papers

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  1. Identification of stem cells in small intestine and colon by marker gene Lgr5

    Authors: Nick Barker, Johan H. van Es, Jeroen Kuipers, Pekka Kujala, Maaike van den Born, Miranda Cozijnsen, Andrea Haegebarth, Jeroen Korving, Harry Begthel, Peter J. Peters, Hans Clevers - Nature 2007 cited by 5,749

  2. A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

    Authors: Norman Sachs, Joep de Ligt, Oded Kopper, Ewa Gogola, Gergana Bounova, Fleur Weeber, Anjali Vanita Balgobind, Karin Wind, Ana Gudelj Gračanin, Harry Begthel, Jeroen Korving, Ruben van Boxtel, Alexandra A. Duarte, Daphne Lelieveld, Arne van Hoeck, Robert F. Ernst, Francis Blokzijl, Isaäc J. Nijman, Marlous Hoogstraat, Marieke van de Ven, David A. Egan, Vittoria Zinzalla, Jürgen Moll, Sylvia F. Boj, Emile E. Voest, Lodewyk F.A. Wessels, Paul Joannes van Diest, Sven Rottenberg, Robert G.J. Vries, Edwin Cuppen, Hans Clevers - Cell 2017 cited by 2,034

  3. Long‐term expanding human airway organoids for disease modeling

    Authors: Norman Sachs, Angelos Papaspyropoulos, Domenique D. Zomer-van Ommen, Inha Heo, Lena Böttinger, Dymph Klay, Fleur Weeber, Guizela Huelsz‐Prince, Nino Iakobachvili, Gimano D. Amatngalim, Joep de Ligt, Arne van Hoeck, Natalie Proost, Marco C. Viveen, Anna Lyubimova, Luc Teeven, Sepideh Derakhshan, Jeroen Korving, Harry Begthel, Johanna F. Dekkers, Kuldeep Kumawat, Emilio Ramos, Matthijs FM van Oosterhout, G. Johan A. Offerhaus, Dominique J. Wiener, Eduardo P. Olimpio, Krijn K. Dijkstra, Egbert F. Smit, Maarten van der Linden, Sridevi Jaksani, Marieke van de Ven, Jos Jonkers, Anne C. Rios, Emile E. Voest, Coline HM van Moorsel, Cornelis K. van der Ent, Edwin Cuppen, Alexander van Oudenaarden, Frank E. J. Coenjaerts, Linde Meyaard, Louis Bont, Peter J. Peters, Sander J. Tans, Jeroen S. van Zon, Sylvia F. Boj, Robert G. Vries, Jeffrey M. Beekman, Hans Clevers - The EMBO Journal 2019 cited by 1,080

  4. An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

    Authors: Oded Kopper, Chris J. de Witte, Kadi Lõhmussaar, Jose Espejo Valle-Inclán, Nizar Hami, Lennart Kester, Anjali Vanita Balgobind, Jeroen Korving, Natalie Proost, Harry Begthel, Lise M. van Wijk, Sonia Aristín Revilla, Rebecca Theeuwsen, Marieke van de Ven, Markus J. van Roosmalen, Bas Ponsioen, Victor W. Ho, Benjamin G. Neel, Tjalling Bosse, Katja N. Gaarenstroom, Harry Vrieling, Maaike P.G. Vreeswijk, P. J. van Diest, Petronella O. Witteveen, Trudy Jonges, Johannes L. Bos, Alexander van Oudenaarden, Ronald P. Zweemer, Hugo J.G. Snippert, Wigard P. Kloosterman, Hans Clevers - Nature Medicine 2019 cited by 839

  5. Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids

    Authors: Huili Hu, Helmuth Gehart, Benedetta Artegiani, Carmen López‐Iglesias, Florijn Dekkers, Onur Başak, Johan H. van Es, Susana M. Chuva de Sousa Lopes, Harry Begthel, Jeroen Korving, Maaike van den Born, Chenhui Zou, Corrine Quirk, Luis Chiriboga, Charles M. Rice, Stephanie Ma, Anne C. Rios, Peter J. Peters, Ype P. de Jong, Hans Clevers - Cell 2018 cited by 853

  6. Sequential cancer mutations in cultured human intestinal stem cells

    Authors: Jarno Drost, Richard H. van Jaarsveld, Bas Ponsioen, Cheryl Zimberlin, Ruben van Boxtel, Arjan Buijs, Norman Sachs, René Overmeer, G. Johan A. Offerhaus, Harry Begthel, Jeroen Korving, Marc van de Wetering, Gerald Schwank, Meike E. W. Logtenberg, Edwin Cuppen, Hugo J.G. Snippert, Jan Paul Medema, Geert J.P.L. Kops, Hans Clevers - Nature 2015 cited by 1,110

  7. Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

    Authors: Nick Barker, Meritxell Huch, Pekka Kujala, Marc van de Wetering, Hugo J.G. Snippert, Johan H. van Es, Toshiro Sato, Daniel E. Stange, Harry Begthel, Maaike van den Born, Esther Danenberg, Stieneke van den Brink, Jeroen Korving, Arie Abo, Peter J. Peters, Nick Wright, Richard Poulsom, Hans Clevers - Cell stem cell 2010 cited by 1,541

  8. Crypt stem cells as the cells-of-origin of intestinal cancer

    Authors: Nick Barker, Rachel A. Ridgway, Johan H. van Es, Marc van de Wetering, Harry Begthel, Maaike van den Born, Esther Danenberg, Alan R. Clarke, Owen J. Sansom, Hans Clevers - Nature 2008 cited by 2,175

  9. In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection

    Authors: Sina Bartfeld, Tülay Bayram, Marc van de Wetering, Meritxell Huch, Harry Begthel, Pekka Kujala, Robert G. Vries, Peter J. Peters, Hans Clevers - Gastroenterology 2014 cited by 830

  10. Oral Mucosal Organoids as a Potential Platform for Personalized Cancer Therapy

    Authors: Else Driehuis, Sigrid Kolders, Sacha Spelier, Kadi Lõhmussaar, Stefan M. Willems, Lot A. Devriese, Remco de Bree, Emma J. de Ruiter, Jeroen Korving, Harry Begthel, Johan H. van Es, Veerle Geurts, Gui-Wei He, Richard H. van Jaarsveld, Rurika Oka, Mauro J. Muraro, Judith Vivié, Maurice M.J.M. Zandvliet, Antoni P. A. Hendrickx, Nino Iakobachvili, Priya Sridevi, Onno Kranenburg, Ruben van Boxtel, Geert J.P.L. Kops, David A. Tuveson, Peter J. Peters, Alexander van Oudenaarden, Hans Clevers - Cancer Discovery 2019 cited by 420

  11. Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation

    Authors: Gui‐Wei He, Lin Lin, Jeff DeMartino, Xuan Zheng, Nadzeya Staliarova, Talya L. Dayton, Harry Begthel, Willine J. van de Wetering, Eduard Bodewes, Jeroen S. van Zon, Sander J. Tans, Carmen Lopez-Iglesias, Peter J. Peters, Wei Wu, Daniel Kotlarz, Christoph Klein, Thanasis Margaritis, Frank C. P. Holstege, Hans Clevers - Cell stem cell 2022 cited by 173

  12. Unlimited in vitro expansion of adult bi‐potent pancreas progenitors through the Lgr5/R‐spondin axis

    Authors: Meritxell Huch, Paola Bonfanti, Sylvia F. Boj, Toshiro Sato, Cindy J.M. Loomans, Marc van de Wetering, Mozhdeh Sojoodi, Vivian Li, Jurian Schuijers, Ana Gudelj Gračanin, Femke Ringnalda, Harry Begthel, Karien M. Hamer, Joyce Mulder, Johan H. van Es, Eelco J.P. de Koning, Robert G. Vries, Harry Heimberg, Hans Clevers - The EMBO Journal 2013 cited by 722

  13. Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters

    Authors: Paul W. Tetteh, Onur Başak, Henner F. Farin, Kay Wiebrands, Kai Kretzschmar, Harry Begthel, Maaike van den Born, Jeroen Korving, Frédéric J. de Sauvage, Johan H. van Es, Alexander van Oudenaarden, Hans Clevers - Cell stem cell 2016 cited by 573

  14. Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution

    Authors: Georg Busslinger, Bas L. Weusten, Auke Bogte, Harry Begthel, Lodewijk A.A. Brosens, Hans Clevers - Cell Reports 2021 cited by 308

  15. Identification of Multipotent Luminal Progenitor Cells in Human Prostate Organoid Cultures

    Authors: Wouter R. Karthaus, Phillip J. Iaquinta, Jarno Drost, Ana Gudelj Gračanin, Ruben van Boxtel, John Wongvipat, Catherine Dowling, Dong Gao, Harry Begthel, Norman Sachs, Robert G.J. Vries, Edwin Cuppen, Yu Chen, Charles L. Sawyers, Hans Clevers - Cell 2014 cited by 739

  16. An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity

    Authors: Camilla Calandrini, Frans Schutgens, Rurika Oka, Thanasis Margaritis, Tito Candelli, Luka Mathijsen, Carola M. E. Ammerlaan, Ravian L. van Ineveld, Sepide Derakhshan, Sanne de Haan, M. Emmy M. Dolman, Philip Lijnzaad, Lars Custers, Harry Begthel, Hindrik H. D. Kerstens, Lindy L. Visser, Maarten B. Rookmaaker, Marianne C. Verhaar, Godelieve A.M. Tytgat, Patrick Kemmeren, Ronald R. de Krijger, Reem Al‐Saadi, Kathy Pritchard‐Jones, Marcel Kool, Anne C. Rios, Marry M. van den Heuvel‐Eibrink, Jan J. Molenaar, Ruben van Boxtel, Frank C. P. Holstege, Hans Clevers, Jarno Drost - Nature Communications 2020 cited by 310

  17. High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells

    Authors: Joep Beumer, Jens Puschhof, Julia Bauzá‐Martinez, Adriana Martínez-Silgado, Rasa Elmentaite, Kylie R. James, Alexander Ross, Delilah Hendriks, Benedetta Artegiani, Georg Busslinger, Bas Ponsioen, Amanda Andersson-Rolf, Aurelia Saftien, Charelle Boot, Kai Kretzschmar, Maarten H. Geurts, Yotam E. Bar‐Ephraïm, Cayetano Pleguezuelos‐Manzano, Yorick Post, Harry Begthel, Franka H. van der Linden, Carmen López‐Iglesias, Willine J. van de Wetering, Reinier van der Linden, Peter J. Peters, Albert J. R. Heck, Joachim Goedhart, Hugo J.G. Snippert, Matthias Zilbauer, Sarah A. Teichmann, Wei Wu, Hans Clevers - Cell 2020 cited by 232

  18. Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer

    Authors: Kadi Lõhmussaar, Rurika Oka, Jose Espejo Valle-Inclán, Milou H.H. Smits, Hila Wardak, Jeroen Korving, Harry Begthel, Natalie Proost, Marieke van de Ven, Onno Kranenburg, Trudy Jonges, Ronald P. Zweemer, Sebastiaan Veersema, Ruben van Boxtel, Hans Clevers - Cell stem cell 2021 cited by 200

  19. Mouse and human urothelial cancer organoids: A tool for bladder cancer research

    Authors: Jasper Mullenders, Evelien de Jongh, Anneta Brousali, Mieke Roosen, Jan P. A. Blom, Harry Begthel, Jeroen Korving, Trudy Jonges, Onno Kranenburg, Richard P. Meijer, Hans Clevers - National Academy of Sciences, Proceedings of the National Academy of Sciences 2019 cited by 283

  20. Patient-derived head and neck cancer organoids allow treatment stratification and serve as a tool for biomarker validation and identification

    Authors: Rosemary Millen, W. W. B. de Kort, Mandy Koomen, Gijs J.F. van Son, Roán Gobits, Bas Penning de Vries, Harry Begthel, Maurice M.J.M. Zandvliet, Patricia Doornaert, Cornelis P.J. Raaijmakers, Maarten H. Geurts, Sjoerd G. Elias, Robert J.J. van Es, Remco de Bree, Lot A. Devriese, Stefan M. Willems, Onno Kranenburg, Else Driehuis, Hans Clevers - Med 2023 cited by 103

  21. Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

    Authors: Johan H. van Es, Mariëlle van Gijn, Orbicia Riccio, Maaike van den Born, Marc Vooijs, Harry Begthel, Miranda Cozijnsen, Sylvie Robine, Doug J. Winton, Freddy Radtke, Hans Clevers - Nature 2005 cited by 1,525

  22. Drug-repurposing screen on patient-derived organoids identifies therapy-induced vulnerability in KRAS-mutant colon cancer

    Authors: Sander Mertens, Maarten A. Huismans, Carla S. Veríssimo, Bas Ponsioen, René Overmeer, Natalie Proost, Olaf van Tellingen, Marieke van de Ven, Harry Begthel, Sylvia F. Boj, Hans Clevers, Jeanine M.L. Roodhart, Johannes L. Bos, Hugo J.G. Snippert - Cell Reports 2023 cited by 69

  23. Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

    Authors: Daniel Pinto, Alex Gregorieff, Harry Begthel, Hans Clevers - Genes & Development 2003 cited by 1,021

  24. Exploring the human lacrimal gland using organoids and single-cell sequencing

    Authors: Marie Bannier-Hélaouët, Yorick Post, Jeroen Korving, Marc Trani Bustos, Helmuth Gehart, Harry Begthel, Yotam E. Bar‐Ephraïm, Jelte van der Vaart, Rachel Kalmann, Saskia M. Imhoff, Hans Clevers - Cell stem cell 2021 cited by 128