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Nick Barker

Active 1997–2025

88
Papers
52,055
Citations
71
h-index
84
i10-index

Citations

Citations per year for Nick Barker1990: 1 citations1994: 3 citations1996: 2 citations1997: 56 citations1998: 145 citations1999: 278 citations2000: 278 citations2001: 301 citations2002: 298 citations2003: 279 citations2004: 286 citations2005: 275 citations2006: 246 citations2007: 252 citations2008: 375 citations2009: 368 citations2010: 538 citations2011: 711 citations2012: 881 citations2013: 820 citations2014: 897 citations2015: 838 citations2016: 774 citations2017: 796 citations2018: 909 citations2019: 1,787 citations2020: 2,137 citations2021: 1,943 citations2022: 1,400 citations2023: 1,115 citations2024: 1,547 citations2025: 847 citations2026: 22 citations1991–1993: no citations, so these years are not shown1995: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 5,725 citing papers, 29% of this breakdownChina: 2,335 citing papers, 11.8% of this breakdownUnited Kingdom: 1,411 citing papers, 7.2% of this breakdownGermany: 1,289 citing papers, 6.5% of this breakdownNetherlands: 1,078 citing papers, 5.5% of this breakdownJapan: 1,004 citing papers, 5.1% of this breakdownFrance: 608 citing papers, 3.1% of this breakdownItaly: 522 citing papers, 2.7% of this breakdownCanada: 519 citing papers, 2.6% of this breakdownSwitzerland: 454 citing papers, 2.3% of this breakdownAustralia: 397 citing papers, 2% of this breakdownSpain: 394 citing papers, 2% of this breakdown
0%29%Other 20.2%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology47.7%
  • Medicine38.4%
  • Engineering4.1%
  • Immunology and Microbiology3.9%
  • Neuroscience2.3%
  • Nursing1.4%
  • Other2.2%

Topics

  • Cancer Cells and Metastasis8.7%
  • Wnt/β-catenin signaling in development and cancer7%
  • Cancer-related gene regulation4.4%
  • 3D Printing in Biomedical Research3%
  • Epigenetics and DNA Methylation2.6%
  • Pluripotent Stem Cells Research2.2%
  • Other72.1%

Coauthors

All papers

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  1. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

    Authors: Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert, Marc van de Wetering, Nick Barker, Daniel E. Stange, Johan H. van Es, Arie Abo, Pekka Kujala, Peter J. Peters, Hans Clevers - Nature 2009 cited by 7,271

  2. Identification of stem cells in small intestine and colon by marker gene Lgr5

    Authors: Nick Barker, Johan H. van Es, Jeroen Kuipers, Pekka Kujala, Maaike van den Born, Miranda Cozijnsen, Andrea Haegebarth, Jeroen Korving, Harry Begthel, Peter J. Peters, Hans Clevers - Nature 2007 cited by 5,749

  3. Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

    Authors: Toshiro Sato, Johan H. van Es, Hugo J.G. Snippert, Daniel E. Stange, Robert G. Vries, Maaike van den Born, Nick Barker, Noah F. Shroyer, Marc van de Wetering, Hans Clevers - Nature 2010 cited by 2,500

  4. Organoids as an in vitro model of human development and disease

    Authors: Aliya Fatehullah, Si Hui Tan, Nick Barker - Nature Cell Biology 2016 cited by 1,495

  5. Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration

    Authors: Nick Barker - Nature Reviews Molecular Cell Biology 2013 cited by 1,320

  6. Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

    Authors: Hugo J.G. Snippert, Laurens G. van der Flier, Toshiro Sato, Johan H. van Es, Maaike van den Born, Carla Kroon-Veenboer, Nick Barker, Allon M. Klein, Jacco van Rheenen, Benjamin D. Simons, Hans Clevers - Cell 2010 cited by 2,000

  7. Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

    Authors: Nick Barker, Meritxell Huch, Pekka Kujala, Marc van de Wetering, Hugo J.G. Snippert, Johan H. van Es, Toshiro Sato, Daniel E. Stange, Harry Begthel, Maaike van den Born, Esther Danenberg, Stieneke van den Brink, Jeroen Korving, Arie Abo, Peter J. Peters, Nick Wright, Richard Poulsom, Hans Clevers - Cell stem cell 2010 cited by 1,541

  8. Crypt stem cells as the cells-of-origin of intestinal cancer

    Authors: Nick Barker, Rachel A. Ridgway, Johan H. van Es, Marc van de Wetering, Harry Begthel, Maaike van den Born, Esther Danenberg, Alan R. Clarke, Owen J. Sansom, Hans Clevers - Nature 2008 cited by 2,175

  9. Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties

    Authors: Sarah Schwitalla, Alexander A. Fingerle, Patrizia Cammareri, Tim Nebelsiek, Serkan İsmail Göktuna, Paul K. Ziegler, Özge Canli, Jarom Heijmans, David J. Huels, Guenievre Moreaux, Rudolf A. Rupec, Markus Gerhard, Roland M. Schmid, Nick Barker, Hans Clevers, Roland Lang, Jens Neumann, Thomas Kirchner, Makoto M. Taketo, Gijs R. van den Brink, Owen J. Sansom, Melek C. Arkan, Florian R. Greten - Cell 2012 cited by 1,077

  10. Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

    Authors: Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek, Nick Barker, Hans Clevers, Bert Vogelstein, Kenneth W. Kinzler - Science 1997 cited by 3,928

  11. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

    Authors: Wim de Lau, Nick Barker, Teck Yew Low, Bon‐Kyoung Koo, Vivian Li, Hans Teunissen, Pekka Kujala, Andrea Haegebarth, Peter J. Peters, Marc van de Wetering, Daniel E. Stange, Johan H. van Es, Daniele Guardavaccaro, Richard B. M. Schasfoort, Yasuaki Mohri, Katsuhiko Nishimori, Shabaz Mohammed, Albert J. R. Heck, Hans Clevers - Nature 2011 cited by 1,292

  12. Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

    Authors: Johan H. van Es, Toshiro Sato, Marc van de Wetering, Anna Lyubimova, Annie Ng Yee Nee, Alex Gregorieff, Nobuo Sasaki, Laura Zeinstra, Maaike van den Born, Jeroen Korving, Anton C. Martens, Nick Barker, Alexander van Oudenaarden, Hans Clevers - Nature Cell Biology 2012 cited by 789

  13. Cell transcriptomic atlas of the non-human primate Macaca fascicularis

    Authors: Lei Han, Xiaoyu Wei, Chuanyu Liu, Giacomo Volpe, Zhenkun Zhuang, Xuanxuan Zou, Zhifeng Wang, Taotao Pan, Yue Yuan, Xiao Zhang, Peng Fan, Pengcheng Guo, Yiwei Lai, Ying Lei, Xingyuan Liu, Feng Yu, Shuncheng Shangguan, Guangyao Lai, Qiuting Deng, Ya Liu, Liang Wu, Quan Shi, Hao Yu, Yun-Ting Huang, Mengnan Cheng, Jiangshan Xu, Yang Liu, Mingyue Wang, Chunqing Wang, Yuanhang Zhang, Duo Xie, Yunzhi Yang, Yeya Yu, Huiwen Zheng, Yanrong Wei, Fubaoqian Huang, Junjie Lei, Waidong Huang, Zhiyong Zhu, Haorong Lu, Bo Wang, Xiaofeng Wei, Fengzhen Chen, Tao Yang, Wensi Du, Jing Chen, Shibo Xu, Juan An, Carl Ward, Zongren Wang, Zhong Pei, Chi‐Wai Wong, Xiaolei Liu, Huafeng Zhang, Mingyuan Liu, Baoming Qin, Axel Schambach, Joan Isern, Liqiang Feng, Yan Liu, Xiangyu Guo, Zhen Liu, Qiang Sun, Patrick H. Maxwell, Nick Barker, Pura Muñoz‐Cánoves, Ying Gu, Jan Mulder, Mathias Uhlén, Tao Tan, Shiping Liu, Huanming Yang, Jian Wang, Yong Hou, Xun Xu, Miguel A. Esteban, Longqi Liu - Nature 2022 cited by 214

  14. Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC −/− Colon Carcinoma

    Authors: Vladimír Kořínek, Nick Barker, Patrice J. Morin, Dick van Wichen, Roel de Weger, Kenneth W. Kinzler, Bert Vogelstein, Hans Clevers - Science 1997 cited by 3,292

  15. The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

    Authors: Javier Muñoz, Daniel E. Stange, Arnout Schepers, Marc van de Wetering, Bon‐Kyoung Koo, Shalev Itzkovitz, Richard Volckmann, Kevin S. Kung, Jan Köster, Sorina Radulescu, Kevin Myant, Rogier Versteeg, Owen J. Sansom, Johan H. van Es, Nick Barker, Alexander van Oudenaarden, Shabaz Mohammed, Albert J. R. Heck, Hans Clevers - The EMBO Journal 2012 cited by 777

  16. Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer

    Authors: Kie Kyon Huang, Kalpana Ramnarayanan, Feng Zhu, Supriya Srivastava, Chang Xu, Angie Lay Keng Tan, Ming‐Hui Lee, Su-Ting Tay, Kakoli Das, Manjie Xing, Aliya Fatehullah, Syed Muhammad Fahmy Alkaff, Tony Kiat Hon Lim, Jonathan Lee, Khek Yu Ho, Steve Rozen, Bin Tean Teh, Nick Barker, Chung King Chia, Christopher Khor, Choon Jin Ooi, Kwong Ming Fock, Jimmy Bok Yan So, Wee Chian Lim, Khoon Lin Ling, Tiing Leong Ang, Andrew Siang Yih Wong, Jaideepraj Rao, Andrea Rajnakova, Lee Guan Lim, Wai Ming Yap, Ming Teh, Khay Guan Yeoh, Patrick Tan - Cancer Cell 2017 cited by 328

  17. Actomyosin-Mediated Cellular Tension Drives Increased Tissue Stiffness and β-Catenin Activation to Induce Epidermal Hyperplasia and Tumor Growth

    Authors: Michael S. Samuel, José I. López, Ewan J. McGhee, Daniel R. Croft, David Strachan, Paul Timpson, June Munro, Ewald Schröder, Jing Zhou, Valerie G. Brunton, Nick Barker, Hans Clevers, Owen J. Sansom, Kurt I. Anderson, Valerie M. Weaver, Michael F. Olson - Cancer Cell 2011 cited by 540

  18. Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate

    Authors: Laurens G. van der Flier, Mariëlle van Gijn, Pantelis Hatzis, Pekka Kujala, Andrea Haegebarth, Daniel E. Stange, Harry Begthel, Maaike van den Born, Victor Guryev, Irma M. Oving, Johan H. van Es, Nick Barker, Peter J. Peters, Marc van de Wetering, Hans Clevers - Cell 2009 cited by 730

  19. Lgr5 marks cycling, yet long-lived, hair follicle stem cells

    Authors: Viljar Jaks, Nick Barker, Maria Kasper, Johan H. van Es, Hugo J.G. Snippert, Hans Clevers, Rune Toftgård - Nature Genetics 2008 cited by 964

  20. Lgr6 Marks Stem Cells in the Hair Follicle That Generate All Cell Lineages of the Skin

    Authors: Hugo J.G. Snippert, Andrea Haegebarth, Maria Kasper, Viljar Jaks, Johan H. van Es, Nick Barker, Marc van de Wetering, Maaike van den Born, Harry Begthel, Robert G. Vries, Daniel E. Stange, Rune Toftgård, Hans Clevers - Science 2010 cited by 756

  21. Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach

    Authors: Marc Leushacke, Si Hui Tan, Angeline M.L. Wong, Swathi Yada, Amin Hajamohideen, Liang Thing Tan, Jasmine Goh, Esther Wong, Simon Denil, Kazuhiro Murakami, Nick Barker - Nature Cell Biology 2017 cited by 279

  22. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

    Authors: Vladimír Kořínek, Nick Barker, Petra Moerer, Elly van Donselaar, Gerwin Huls, Peter J. Peters, Hans Clevers - Nature Genetics 1998 cited by 1,569

  23. AQP5 enriches for stem cells and cancer origins in the distal stomach

    Authors: Si Hui Tan, Swathi Yada, Shawna Tan, Jasmine Goh, Ryo Seishima, Kazuhiro Murakami, Masanobu Oshima, Toshikatsu Tsuji, Phyllis Phuah, Liang Thing Tan, Esther Wong, Aliya Fatehullah, Taotao Sheng, Shamaine Wei Ting Ho, Heike I. Grabsch, Supriya Srivastava, Ming Teh, Simon Denil, Seri Mustafah, Patrick Tan, Asim Shabbir, Jimmy Bok Yan So, Khay Guan Yeoh, Nick Barker - Nature 2020 cited by 178

  24. A tumour-resident Lgr5+ stem-cell-like pool drives the establishment and progression of advanced gastric cancers

    Authors: Aliya Fatehullah, Yumi Terakado, Sowmya Sagiraju, T. L. Tan, Taotao Sheng, Shawna Tan, Kazuhiro Murakami, Y. Swathi, Nicholas Ang, Ravisankar Rajarethinam, Tan Ming, Patrick Tan, Bob S. L. Lee, Nick Barker - Nature Cell Biology 2021 cited by 125