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Francesco Iorio

Active 2005–2025

93
Papers
23,522
Citations
46
h-index
73
i10-index

Citations

Citations per year for Francesco Iorio1991: 1 citations1994: 1 citations1997: 2 citations2000: 1 citations2001: 1 citations2002: 2 citations2003: 2 citations2006: 3 citations2007: 2 citations2008: 11 citations2009: 17 citations2010: 56 citations2011: 76 citations2012: 119 citations2013: 159 citations2014: 200 citations2015: 245 citations2016: 322 citations2017: 378 citations2018: 427 citations2019: 1,010 citations2020: 1,421 citations2021: 1,554 citations2022: 1,246 citations2023: 867 citations2024: 1,340 citations2025: 747 citations2026: 77 citations1992–1993: no citations, so these years are not shown1995–1996: no citations, so these years are not shown1998–1999: no citations, so these years are not shown2004–2005: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,288 citing papers, 22.5% of this breakdownChina: 1,875 citing papers, 12.8% of this breakdownUnited Kingdom: 1,162 citing papers, 7.9% of this breakdownGermany: 830 citing papers, 5.7% of this breakdownItaly: 668 citing papers, 4.6% of this breakdownNetherlands: 497 citing papers, 3.4% of this breakdownIndia: 426 citing papers, 2.9% of this breakdownCanada: 421 citing papers, 2.9% of this breakdownSpain: 409 citing papers, 2.8% of this breakdownFrance: 373 citing papers, 2.5% of this breakdownJapan: 347 citing papers, 2.4% of this breakdownAustralia: 316 citing papers, 2.2% of this breakdown
0%22.5%Other 27.4%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology38.3%
  • Medicine31.7%
  • Computer Science18.1%
  • Engineering4.1%
  • Immunology and Microbiology1.6%
  • Physics and Astronomy1.4%
  • Other4.8%

Topics

  • Computational Drug Discovery Methods7.3%
  • Bioinformatics and Genomic Networks5.2%
  • Cancer Genomics and Diagnostics3.9%
  • Cancer Cells and Metastasis3.2%
  • CRISPR and Genetic Engineering2.1%
  • Gene expression and cancer classification2%
  • Other76.3%

Coauthors

All papers

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  1. Drug repurposing: progress, challenges and recommendations

    Authors: Sudeep Pushpakom, Francesco Iorio, Patrick A. Eyers, Katherine J. Escott, Shirley Hopper, Andrew D. Wells, Andrew J. Doig, Tim Guilliams, Joanna Latimer, Christine J. McNamee, Alan Norris, Philippe Sanséau, David Cavalla, Munir Pirmohamed - Nature Reviews Drug Discovery 2018 cited by 4,668

  2. Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

    Authors: Marc van de Wetering, Hayley E. Francies, Joshua M. Francis, Gergana Bounova, Francesco Iorio, Apollo Pronk, Winan J. van Houdt, Joost van Gorp, Amaro Taylor‐Weiner, Lennart Kester, Anne McLaren-Douglas, Joyce Blokker, Sridevi Jaksani, Sina Bartfeld, Richard Volckman, Peter van Sluis, Vivian Li, Sara Seepo, Chandra Sekhar Pedamallu, Kristian Cibulskis, Scott L. Carter, Aaron McKenna, Michael S. Lawrence, Lee Lichtenstein, Chip Stewart, Jan Köster, Rogier Versteeg, Alexander van Oudenaarden, Julio Sáez-Rodríguez, Robert G.J. Vries, Gad Getz, Lodewyk F.A. Wessels, Michael R. Stratton, Ultan McDermott, Matthew Meyerson, Mathew J. Garnett, Hans Clevers - Cell 2015 cited by 2,472

  3. A Landscape of Pharmacogenomic Interactions in Cancer

    Authors: Francesco Iorio, Theo Knijnenburg, Daniël J. Vis, Graham R. Bignell, Michael P. Menden, Michaël Schubert, Nanne Aben, Emanuel Gonçalves, Syd Barthorpe, Howard Lightfoot, Thomas Cokelaer, Patricia Greninger, Ewald van Dyk, Han Chang, Heshani de Silva, Holger Heyn, Xianming Deng, Regina K. Egan, Qingsong Liu, Tatiana Mironenko, Xeni Mitropoulos, Laura Richardson, Jinhua Wang, Tinghu Zhang, Sebastián Morán, Sergi Sayols, Maryam Soleimani, David Tamborero, Núria López-Bigas, Petra Ross‐Macdonald, Manel Esteller, Nathanael S. Gray, Daniel A. Haber, Michael R. Stratton, Cyril H. Benes, Lodewyk F.A. Wessels, Julio Sáez-Rodríguez, Ultan McDermott, Mathew J. Garnett - Cell 2016 cited by 2,304

  4. Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens

    Authors: Fiona M. Behan, Francesco Iorio, Gabriele Picco, Emanuel Gonçalves, Charlotte Beaver, Giorgia Migliardi, Rita Santos, Yanhua Rao, Francesco Sassi, Marika Pinnelli, Rizwan Ansari, Sarah Harper, David A. Jackson, Rebecca McRae, Rachel Pooley, Piers Wilkinson, Dieudonne van der Meer, David J. Dow, Carolyn Buser‐Doepner, Andrea Bertotti, Livio Trusolino, Euan A. Stronach, Julio Sáez-Rodríguez, Kosuke Yusa, Mathew J. Garnett - Nature 2019 cited by 1,455

  5. Systematic identification of genomic markers of drug sensitivity in cancer cells

    Authors: Mathew J. Garnett, Elena J. Edelman, Sonja J. Heidorn, Chris Greenman, Anahita Dastur, King Wai Lau, Patricia Greninger, I. Richard Thompson, Xi Luo, Jorge Soares, Qingsong Liu, Francesco Iorio, Didier Surdez, Li Chen, Randy Milano, Graham R. Bignell, Ah Ting Tam, Helen Davies, Jesse A. Stevenson, Syd Barthorpe, Stephen Lutz, Fiona Kogera, Karl Lawrence, Anne McLaren-Douglas, Xeni Mitropoulos, Tatiana Mironenko, Helen Thi, Laura Richardson, Wenjun Zhou, Frances Jewitt, Tinghu Zhang, Patrick O’Brien, Jessica L. Boisvert, Stacey Price, Wooyoung Hur, Wanjuan Yang, Xianming Deng, Adam P. Butler, Hwan Geun Choi, Jae Won Chang, José Baselga, Ivan Stamenkovic, Jeffrey A. Engelman, Sreenath V. Sharma, Olivier Delattre, Julio Sáez-Rodríguez, Nathanael S. Gray, Jeffrey Settleman, P. Andrew Futreal, Daniel A. Haber, Michael R. Stratton, Sridhar Ramaswamy, Ultan McDermott, Cyril H. Benes - Nature 2012 cited by 2,601

  6. Convolutional Neural Networks for Steady Flow Approximation

    Authors: Xiaoxiao Guo, Wei Li, Francesco Iorio - SIGKDD International Conference on Knowledge Discovery and Data Mining 2016 cited by 701

  7. A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

    Authors: Konstantinos Tzelepis, Hiroko Koike-Yusa, Étienne De Braekeleer, Yilong Li, Emmanouil Metzakopian, Oliver M. Dovey, Annalisa Mupo, Vera Grinkevich, Meng Li, Milena Mazan, Malgorzata Gozdecka, Shuhei Ohnishi, Jonathan Cooper, Miten Patel, Thomas McKerrell, Bin Chen, Ana Filipa Domingues, Paolo Gallipoli, Sarah A. Teichmann, Hannes Ponstingl, Ultan McDermott, Julio Sáez-Rodríguez, Brian J.P. Huntly, Francesco Iorio, Cristina Pina, George S. Vassiliou, Kosuke Yusa - Cell Reports 2016 cited by 834

  8. Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis

    Authors: Mia Petljak, Ludmil B. Alexandrov, Jonathan Brammeld, Stacey Price, David C. Wedge, Sebastian Großmann, Kevin J. Dawson, Young Seok Ju, Francesco Iorio, José M. C. Tubío, Ching Chiek Koh, Ilias Georgakopoulos‐Soares, Bernardo Rodríguez–Martín, Burçak Otlu, Sarah O’Meara, Adam P. Butler, Andrew Menzies, Shriram G. Bhosle, Keiran Raine, David Jones, Jon W. Teague, Kathryn Beal, Calli Latimer, Laura P. O’Neill, Jorge Zamora, Elizabeth Anderson, Nikita Patel, Mark Maddison, Bee Ling Ng, Jennifer Graham, Mathew J. Garnett, Ultan McDermott, Serena Nik‐Zainal, Peter J. Campbell, Michael R. Stratton - Cell 2019 cited by 450

  9. Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties

    Authors: Michael P. Menden, Francesco Iorio, Mathew Garnett, Ultan McDermott, Cyril Benes, Pedro J. Ballester, Julio Saez-Rodriguez - PLoS ONE 2013 cited by 567

  10. Phenotypic plasticity and genetic control in colorectal cancer evolution

    Authors: Jacob Househam, Timon Heide, George D. Cresswell, Inmaculada Spiteri, Christopher Kimberley, Luís Zapata, Claire Lynn, Chela James, Maximilian Mossner, Javier Fernández-Mateos, Alessandro Vinceti, Ann‐Marie Baker, Calum Gabbutt, Alison Berner, Melissa Schmidt, Bingjie Chen, Eszter Lakatos, Vinaya Gunasri, Daniel Nichol, Helena Costa, Miriam Mitchinson, Daniele Ramazzotti, Benjamin Werner, Francesco Iorio, Marnix Jansen, Giulio Caravagna, C. Barnes, Darryl Shibata, John Bridgewater, Manuel Rodriguez‐Justo, Luca Magnani, Andrea Sottoriva, Trevor A. Graham - Nature 2022 cited by 182

  11. Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

    Authors: Joshua M. Dempster, Clare Pacini, Sasha Pantel, Fiona M. Behan, Thomas Green, John M. Krill-Burger, Charlotte Beaver, Scott T. Younger, Victor Zhivich, Hanna Najgebauer, Felicity Allen, Emanuel Gonçalves, Rebecca Shepherd, John G. Doench, Kosuke Yusa, Francisca Vázquez, Leopold Parts, Jesse S. Boehm, Todd R. Golub, William C. Hahn, David E. Root, Mathew J. Garnett, Aviad Tsherniak, Francesco Iorio - Nature Communications 2019 cited by 282

  12. Heterogeneity of genomic evolution and mutational profiles in multiple myeloma

    Authors: Niccolò Bolli, Hervé Avet‐Loiseau, David C. Wedge, Peter Van Loo, Ludmil B. Alexandrov, Iñigo Martincorena, Kevin J. Dawson, Francesco Iorio, Serena Nik‐Zainal, Graham R. Bignell, Jonathan Hinton, Yilong Li, José M. C. Tubío, Stuart McLaren, Sarah O' Meara, Adam P. Butler, Jon W. Teague, Laura Mudie, Élizabeth Anderson, Naim U. Rashid, Yu‐Tzu Tai, Masood A. Shammas, Adam S. Sperling, Mariateresa Fulciniti, Paul G. Richardson, Giovanni Parmigiani, Florence Magrangeas, Stéphane Minvielle, Philippe Moreau, Michel Attal, Thierry Façon, P. Andrew Futreal, Kenneth C. Anderson, Peter J. Campbell, Nikhil C. Munshi - Nature Communications 2014 cited by 906

  13. Discovery of drug mode of action and drug repositioning from transcriptional responses

    Authors: Francesco Iorio, Roberta Bosotti, Emanuela Scacheri, Vincenzo Belcastro, Pratibha Mithbaokar, Rosa Ferriero, Loredana Murino, Roberto Tagliaferri, Nicola Brunetti‐Pierri, Antonella Isacchi, Diego di Bernardo - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 852

  14. Combinatorial CRISPR screen identifies fitness effects of gene paralogues

    Authors: Nicola Thompson, Marco Ranzani, Louise van der Weyden, Vivek Iyer, Victoria Offord, Alastair Droop, Fiona M. Behan, Emanuel Gonçalves, Anneliese O. Speak, Francesco Iorio, James Hewinson, Victoria Harle, Holly Robertson, Elizabeth Anderson, Beiyuan Fu, Fengtang Yang, Guido Zagnoli-Vieira, Phil Chapman, Martin Del Castillo Velasco‐Herrera, Mathew J. Garnett, Stephen P. Jackson, David J. Adams - Nature Communications 2021 cited by 136

  15. Project Score database: a resource for investigating cancer cell dependencies and prioritizing therapeutic targets

    Authors: Lisa Dwane, Fiona M. Behan, Emanuel J. V. Gonçalves, Howard Lightfoot, Wanjuan Yang, Dieudonne van der Meer, Rebecca Shepherd, Miguel Pignatelli, Francesco Iorio, Mathew Garnett - Nucleic Acids Research, Nucleic Acids Res. 2020 cited by 128

  16. Pharmacogenomic agreement between two cancer cell line data sets

    Authors: Nicolas Stransky, Mahmoud Ghandi, Gregory V. Kryukov, Levi A. Garraway, Arnaud Amzallag, Iulian Pruteanu-Malinici, Daniel A. Haber, Sridhar Ramaswamy, Cyril H. Benes, Joseph Lehár, Manway Liu, Dmitriy Sonkin, Audrey Kauffmann, Kavitha Venkatesan, Elena J. Edelman, Markus Riester, Jordi Barretina, Giordano Caponigro, Robert Schlegel, William R. Sellers, Frank Stegmeier, Michael Morrissey, Michael P. Menden, Francesco Iorio, Julio Saez-Rodriguez, Michael R. Stratton, Ultan McDermott, Mathew J. Garnett - Nature 2015 cited by 444

  17. A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization

    Authors: Clare Pacini, Emma L. Duncan, Emanuel Gonçalves, James Gilbert, Shriram G. Bhosle, Stuart Horswell, Emre Karakoç, Howard Lightfoot, Edward Curry, Francesc Muyas, Monsif Bouaboula, Chandra Sekhar Pedamallu, Isidro Cortés‐Ciriano, Fiona M. Behan, Lykourgos‐Panagiotis Zalmas, Andrew Barthorpe, Hayley E. Francies, Steve Rowley, Jack Pollard, Pedro Beltrão, Leopold Parts, Francesco Iorio, Mathew J. Garnett - Cancer Cell 2024 cited by 91

  18. Drug mechanism‐of‐action discovery through the integration of pharmacological and CRISPR screens

    Authors: Emanuel Gonçalves, Aldo Segura‐Cabrera, Clare Pacini, Gabriele Picco, Fiona M. Behan, Patricia Jaaks, Elizabeth A. Coker, Donny van der Meer, Andrew Barthorpe, Howard Lightfoot, Tatiana Mironenko, Alexandra Beck, Laura Richardson, Wanjuan Yang, Ermira Lleshi, James Hall, Charlotte Tolley, Caitlin Hall, Iman Mali, Frances Thomas, James Morris, Andrew R. Leach, James T. Lynch, Ben Sidders, Claire Crafter, Francesco Iorio, Stephen E. Fawell, Mathew J. Garnett - Molecular Systems Biology 2020 cited by 112

  19. Cancer research needs a better map

    Authors: Jesse S. Boehm, Mathew J. Garnett, David J. Adams, Hayley E. Francies, Todd R. Golub, William C. Hahn, Francesco Iorio, James M. McFarland, Leopold Parts, Francisca Vázquez - Nature 2021 cited by 107

  20. Minimal genome-wide human CRISPR-Cas9 library

    Authors: Emanuel Gonçalves, Mark Thomas, Fiona M. Behan, Gabriele Picco, Clare Pacini, Felicity Allen, Alessandro Vinceti, Mamta Sharma, David A. Jackson, Stacey Price, Charlotte Beaver, Oliver M. Dovey, David Parry-Smith, Francesco Iorio, Leopold Parts, Kosuke Yusa, Mathew J. Garnett - Genome biology 2021 cited by 95

  21. Transcription Factor Activities Enhance Markers of Drug Sensitivity in Cancer

    Authors: Luz García‐Alonso, Francesco Iorio, Angela Matchan, Nuno A. Fonseca, Patricia Jaaks, Gareth Peat, Miguel Pignatelli, Fiammetta Falcone, Cyril H. Benes, Ian Dunham, Graham R. Bignell, Simon S. McDade, Mathew J. Garnett, Julio Sáez-Rodríguez - Cancer Research 2017 cited by 235

  22. CellMinerCDB for Integrative Cross-Database Genomics and Pharmacogenomics Analyses of Cancer Cell Lines

    Authors: Vinodh N. Rajapakse, Augustin Luna, Mihoko Yamade, Lisa Loman, Sudhir Varma, Margot Sunshine, Francesco Iorio, Fabrício G. Sousa, Fathi Elloumi, Mirit I. Aladjem, Anish Thomas, Chris Sander, Kurt W. Kohn, Cyril H. Benes, Mathew J. Garnett, William C. Reinhold, Yves Pommier - iScience 2018 cited by 166

  23. Logic models to predict continuous outputs based on binary inputs with an application to personalized cancer therapy

    Authors: Theo Knijnenburg, Gunnar W. Klau, Francesco Iorio, Mathew J. Garnett, Ultan McDermott, Ilya Shmulevich, Lodewyk F.A. Wessels - Scientific Reports 2016 cited by 69

  24. Integrated cross-study datasets of genetic dependencies in cancer

    Authors: Clare Pacini, Joshua M. Dempster, Isabella Boyle, Emanuel Gonçalves, Hanna Najgebauer, Emre Karakoç, Dieudonne van der Meer, Andrew Barthorpe, Howard Lightfoot, Patricia Jaaks, James M. McFarland, Mathew J. Garnett, Aviad Tsherniak, Francesco Iorio - Nature Communications 2020 cited by 339