Frank McKeon
Active 1983–2025
- 87
- Papers
- 30,804
- Citations
- 79
- h-index
- 86
- i10-index
Citations
Citation sources
Countries
Institutions
- Harvard University2%
- Howard Hughes Medical Institute1.1%
- Inserm0.7%
- Johns Hopkins University0.7%
- Stanford University0.7%
- Brigham and Women's Hospital0.6%
- Other94.2%
Fields
- Biochemistry, Genetics and Molecular Biology49.6%
- Medicine43.9%
- Immunology and Microbiology2.4%
- Neuroscience1.8%
- Agricultural and Biological Sciences0.5%
- Engineering0.4%
- Other1.4%
Topics
- Cancer-related Molecular Pathways5.9%
- Microtubule and mitosis dynamics3.4%
- Signaling Pathways in Disease2.8%
- RNA Research and Splicing2.6%
- Nuclear Structure and Function2.5%
- Genomics and Chromatin Dynamics2.5%
- Other80.3%
Coauthors
- Christopher P. Crum28
- Annie Yang24
- Wa Xian21
- Yusuke Yamamoto10
- Daniel Caput7
- Bradley J. Quade6
- Matthew Vincent6
- Deqin Sun5
- Futoshi Shibasaki5
- Mourad Kaghad5
- Roderick T. Bronson5
- Xia Wang5
- Aida Čviko4
- Brooke E. Howitt4
- Edwin R. Price4
- Gang Ning4
- George L. Mutter4
- Khek Yu Ho4
- Marc W. Kirschner4
- Marisa R. Nucci4
- Mark L. Metersky4
- Michaël Herfs4
- Shan Wang4
- Volker Dötsch4
All papers
- Iron addiction: a novel therapeutic target in ovarian cancer
Authors: Debargha Basuli, Lia Tesfay, Zhao Deng, Bincy Paul, Yusuke Yamamoto, Gang Ning, Wa Xian, Frank McKeon, Miranda L. Lynch, Christopher P. Crum, Poornima Hegde, Mark Brewer, Xiaohong Wang, Lance D. Miller, Nathaniel A. Dyment, Frank M. Torti, Suzy V. Torti - Oncogene 2017 cited by 466
- Molecular targeting therapies for neuroblastoma: Progress and challenges
Authors: Atif Zafar, Wei Wang, Gang Liu, Xinjie Wang, Wa Xian, Frank McKeon, Jennifer H. Foster, Jia Zhou, Ruiwen Zhang - Medicinal Research Reviews 2020 cited by 390
- p63+Krt5+ distal airway stem cells are essential for lung regeneration
Authors: Wei Zuo, Ting Zhang, Daniel Zheng'An Wu, Shou Ping Guan, Audrey-Ann Liew, Yusuke Yamamoto, Xia Wang, Siew Joo Lim, Matthew Vincent, Mark D. Lessard, Christopher P. Crum, Wa Xian, Frank McKeon - Nature 2014 cited by 559
- Distal Airway Stem Cells Yield Alveoli In Vitro and during Lung Regeneration following H1N1 Influenza Infection
Authors: Pooja Kumar, Yuanyu Hu, Yusuke Yamamoto, Neo Boon Hoe, Tay Seok Wei, Dakai Mu, Yan Sun, Lim Siew Joo, Rania Dagher, Elisabeth M. Zielonka, D.Y. Wang, Bing Lim, Vincent Chow, Christopher P. Crum, Wa Xian, Frank McKeon - Cell 2011 cited by 602
- MDM2 Inhibitors for Cancer Therapy: The Past, Present, and Future
Authors: Wei Wang, Najah Albadari, Yi Du, Josef F. Fowler, Hannah T. Sang, Wa Xian, Frank McKeon, Wěi Li, Jia Zhou, Ruiwen Zhang - Pharmacological Reviews 2024 cited by 119
- p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
Authors: Annie Yang, Ronen Schweitzer, Deqin Sun, Mourad Kaghad, Nancy M. Walker, Roderick T. Bronson, Cliff Tabin, Arlene H. Sharpe, Daniel Caput, Christopher P. Crum, Frank McKeon - Nature 1999 cited by 2,256
- Regenerative Metaplastic Clones in COPD Lung Drive Inflammation and Fibrosis
Authors: Wei Rao, Wang Shan, Marcin Dulęba, Suchan Niroula, Kristina Göller, Jingzhong Xie, Rajasekaran Mahalingam, Rahul Neupane, Audrey-Ann Liew, Matthew Vincent, Kenichi Okuda, Wanda K. O’Neal, Richard C. Boucher, Burton F. Dickey, Michael E. Wechsler, Omar M. Ibrahim, John F. Engelhardt, Tinne C. J. Mertens, Wei Wang, Soma Jyothula, Christopher P. Crum, Harry Karmouty‐Quintana, Kalpaj R. Parekh, Mark L. Metersky, Frank McKeon, Wa Xian - Cell 2020 cited by 173
- Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment
Authors: Yibo Fan, Yuan Li, Xiaodan Yao, Jiangkang Jin, Ailing W. Scott, Bovey Liu, Shan Wang, Longfei Huo, Ying Wang, Ruiping Wang, Melissa Pool Pizzi, Lang Ma, Shan Shao, Matheus Sewastjanow‐Silva, Rebecca Waters, Deyali Chatterjee, Bin Liu, Namita Shanbhag, Guang Peng, George A. Călin, Paweł K. Mazur, Samir Hanash, Jo Ishizawa, Yuki Hirata, Osamu Nagano, Zhenning Wang, Linghua Wang, Wa Xian, Frank McKeon, Jaffer A. Ajani, Shumei Song - Gut 2022 cited by 78
- p63 identifies keratinocyte stem cells
Authors: Graziella Pellegrini, Elena Dellambra, Osvaldo Golisano, Enrica Martinelli, Ivana Fantozzi, Sergio Bondanza, Diego Ponzin, Frank McKeon, Michele De Luca - National Academy of Sciences, Proceedings of the National Academy of Sciences 2001 cited by 1,369
- p63 protects the female germ line during meiotic arrest
Authors: Eun-Kyung Suh, Annie Yang, Arminja N. Kettenbach, Casimir Bamberger, Ala H. Michaelis, Zhou Zhu, Julia A. Elvin, Roderick T. Bronson, Christopher P. Crum, Frank McKeon - Nature 2006 cited by 570
- p63, a p53 Homolog at 3q27–29, Encodes Multiple Products with Transactivating, Death-Inducing, and Dominant-Negative Activities
Authors: Annie Yang, Mourad Kaghad, Yunmei Wang, Emily S. Gillett, Mark D. Fleming, Volker Dötsch, Nancy C. Andrews, Daniel Caput, Frank McKeon - Molecular Cell 1998 cited by 2,075
- p63 Is Essential for the Proliferative Potential of Stem Cells in Stratified Epithelia
Authors: Makoto Senoo, Filipa R. Pinto, Christopher P. Crum, Frank McKeon - Cell 2007 cited by 886
- Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis
Authors: Rebecca Heald, Frank McKeon - Cell 1990 cited by 660
- A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer
Authors: Michaël Herfs, Yusuke Yamamoto, Anna Laury, Xia Wang, Marisa R. Nucci, Margaret E. McLaughlin-Drubin, Karl Münger, Sarah Feldman, Frank McKeon, Wa Xian, Christopher P. Crum - National Academy of Sciences, Proceedings of the National Academy of Sciences 2012 cited by 436
- Targeting the p53-MDM2 pathway for neuroblastoma therapy: Rays of hope
Authors: Atif Zafar, Wei Wang, Gang Liu, Wa Xian, Frank McKeon, Jia Zhou, Ruiwen Zhang - Cancer Letters 2020 cited by 114
- Cloning and variation of ground state intestinal stem cells
Authors: Xia Wang, Yusuke Yamamoto, Lane Wilson, Ting Zhang, Brooke E. Howitt, Melissa A. Farrow, Florian Kern, Gang Ning, Hong Yue, Chiea Chuen Khor, B. Chevalier, Denis Bertrand, Lingyan Wu, Niranjan Nagarajan, Francisco Sylvester, Jeffrey S. Hyams, Thomas J. Devers, Roderick T. Bronson, D. Borden Lacy, Khek Yu Ho, Christopher P. Crum, Frank McKeon, Wa Xian - Nature 2015 cited by 200
- Cloning a profibrotic stem cell variant in idiopathic pulmonary fibrosis
Authors: Shan Wang, Wei Rao, Ashley Hoffman, Jennifer Lin, Justin Li, Tao Lin, Audrey-Ann Liew, Matthew Vincent, Tinne C. J. Mertens, Harry Karmouty‐Quintana, Christopher P. Crum, Mark L. Metersky, David A. Schwartz, Peter J. Davies, Clifford Stephan, Soma Jyothula, Ajay Sheshadri, Erik E. Suarez, Howard J. Huang, John F. Engelhardt, Burton F. Dickey, Kalpaj R. Parekh, Frank McKeon, Wa Xian - Science Translational Medicine 2023 cited by 30
- Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated cdc2 kinase
Authors: Rebecca Heald, Michael McLoughlin, Frank McKeon - Cell 1993 cited by 470
- REDD1, a Developmentally Regulated Transcriptional Target of p63 and p53, Links p63 to Regulation of Reactive Oxygen Species
Authors: Leif W. Ellisen, Kate D Ramsayer, Cory M. Johannessen, Annie Yang, Hideyuki Beppu, Karolina Minda, Jonathan D. Oliner, Frank McKeon, Daniel A. Haber - Molecular Cell 2002 cited by 480
- DNA Damage in Oocytes Induces a Switch of the Quality Control Factor TAp63α from Dimer to Tetramer
Authors: Gregor B. Deutsch, Elisabeth M. Zielonka, Daniel Coutandin, Tobias Weber, Birgit Schäfer, Jens Hannewald, Laura M. Luh, Florian Durst, Mohamed F. M. Ibrahim, Jan Hoffmann, F. Niesen, Aycan Sentürk, Hana Kunkel, Bernd Brutschy, Enrico Schleiff, Stefan Knapp, Amparo Acker‐Palmer, Manuel Grez, Frank McKeon, Volker Dötsch - Cell 2011 cited by 144
- Relationships between p63 Binding, DNA Sequence, Transcription Activity, and Biological Function in Human Cells
Authors: Annie Yang, Zhou Zhu, Philipp Kapranov, Frank McKeon, George M. Church, T Gingeras, Kevin Struhl - Molecular Cell 2006 cited by 281
- Inflammatory Activity of Epithelial Stem Cell Variants from Cystic Fibrosis Lungs Is Not Resolved by CFTR Modulators
Authors: Shan Wang, Suchan Niroula, Ashley Hoffman, Melika Khorrami, Melina Khorrami, Feng Yuan, Grace N. Gasser, Soon Ho Choi, Bovey Liu, Justin Li, Mark L. Metersky, Matthew Vincent, Christopher P. Crum, Richard C. Boucher, Harry Karmouty‐Quintana, Howard J. Huang, Ajay Sheshadri, Burton F. Dickey, Kalpaj R. Parekh, John F. Engelhardt, Frank McKeon, Wa Xian - American Journal of Respiratory and Critical Care Medicine 2023 cited by 18
- Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers
Authors: Mourad Kaghad, H Bonnet, Annie Yang, Laurent Créancier, Jean-Christophe Biscan, Alexandre Valent, A Minty, Pascale Chalon, Jean-Michel Lélias, Xavier Dumont, Pascual Ferrara, Frank McKeon, Daniel Caput - Cell 1997 cited by 1,634
- Ca 2+ -Induced Apoptosis Through Calcineurin Dephosphorylation of BAD
Authors: Hong‐Gang Wang, Nuzhat Pathan, Iryna M. Ethell, Stanisław Krajewski, Yu Yamaguchi, Futoshi Shibasaki, Frank McKeon, Tanya Bobo, Thomas Franke, John C. Reed - Science 1999 cited by 1,131
