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Michael C. Holmes

Active 1979–2025

69
Papers
24,046
Citations
62
h-index
66
i10-index

Citations

Citations per year for Michael C. Holmes1981: 1 citations1982: 1 citations1984: 1 citations1985: 2 citations1986: 3 citations1987: 2 citations1988: 1 citations1989: 2 citations1990: 3 citations1991: 1 citations1992: 2 citations1994: 1 citations1995: 2 citations1996: 4 citations1997: 10 citations1998: 3 citations1999: 4 citations2000: 8 citations2001: 7 citations2002: 6 citations2003: 22 citations2004: 10 citations2005: 15 citations2006: 24 citations2007: 36 citations2008: 71 citations2009: 123 citations2010: 198 citations2011: 305 citations2012: 432 citations2013: 556 citations2014: 598 citations2015: 615 citations2016: 481 citations2017: 402 citations2018: 343 citations2019: 873 citations2020: 871 citations2021: 809 citations2022: 597 citations2023: 393 citations2024: 583 citations2025: 314 citations2026: 7 citations1983: no citations, so this year is not shown1993: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,554 citing papers, 34.2% of this breakdownChina: 779 citing papers, 10.4% of this breakdownGermany: 446 citing papers, 6% of this breakdownUnited Kingdom: 443 citing papers, 5.9% of this breakdownFrance: 309 citing papers, 4.1% of this breakdownItaly: 252 citing papers, 3.4% of this breakdownJapan: 238 citing papers, 3.2% of this breakdownCanada: 201 citing papers, 2.7% of this breakdownIndia: 185 citing papers, 2.5% of this breakdownNetherlands: 162 citing papers, 2.2% of this breakdownSouth Korea: 153 citing papers, 2.1% of this breakdownAustralia: 150 citing papers, 2% of this breakdown
0%34.2%Other 21.3%

Institutions

Fields

  • Biochemistry, Genetics and Molecular Biology67.2%
  • Medicine22.9%
  • Immunology and Microbiology5.1%
  • Agricultural and Biological Sciences1.8%
  • Neuroscience1%
  • Materials Science0.5%
  • Other1.5%

Topics

  • CRISPR and Genetic Engineering17.7%
  • Virus-based gene therapy research6.4%
  • CAR-T cell therapy research5.5%
  • RNA Interference and Gene Delivery3.9%
  • Pluripotent Stem Cells Research3.6%
  • Advanced biosensing and bioanalysis techniques2.7%
  • Other60.2%

Coauthors

All papers

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  1. Genome editing with engineered zinc finger nucleases

    Authors: Fyodor D. Urnov, Edward J. Rebar, Michael C. Holmes, H. Steve Zhang, Philip D. Gregory - Nature Reviews Genetics 2010 cited by 2,267

  2. A TALE nuclease architecture for efficient genome editing

    Authors: Jeffrey C. Miller, Siyuan Tan, Guijuan Qiao, Kyle A. Barlow, Jianbin Wang, Danny F. Xia, Xiangdong Meng, David E. Paschon, Elo Leung, Sarah J. Hinkley, Gladys P Dulay, Kevin Hua, Irina Ankoudinova, Gregory J. Cost, Fyodor D. Urnov, H Steve Zhang, Michael C. Holmes, Lei Zhang, Philip D. Gregory, Edward J. Rebar - Nature Biotechnology 2010 cited by 2,093

  3. Off-the-shelf, steroid-resistant, IL13Rα2-specific CAR T cells for treatment of glioblastoma

    Authors: Christine E. Brown, Analiz Rodriguez, Joycelynne Palmer, Julie R. Ostberg, Araceli Naranjo, Jamie R. Wagner, Brenda Aguilar, Renate Starr, Lihong Weng, Timothy W. Synold, Vivi Tran, Shelley Wang, Andreas Reik, Massimo D’Apuzzo, Julie A. Ressler, Yuanyue Zhou, Matthew Mendel, Philip D. Gregory, Michael C. Holmes, Winson W. Tang, Stephen J. Forman, Michael C. Jensen, Behnam Badie - Neuro-Oncology 2022 cited by 143

  4. Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV

    Authors: Pablo Tebas, David Stein, Winson W. Tang, Ian Frank, Shelley Q. Wang, Gary Lee, S. Kaye Spratt, Richard Surosky, Martin Giedlin, Geoff Nichol, Michael C. Holmes, Philip D. Gregory, Dale Ando, Michael Kalos, Ronald G. Collman, Gwendolyn Binder-Scholl, Gabriela Plesa, Wei‐Ting Hwang, Bruce L. Levine, Carl H. June - New England Journal of Medicine 2014 cited by 1,348

  5. A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR

    Authors: Hiroki Torikai, Andreas Reik, Pei-Qi Liu, Yuanyue Zhou, Ling Zhang, Sourindra N. Maiti, Helen Huls, Jeffrey C. Miller, Partow Kebriaei, Brian Rabinovitch, Dean A. Lee, Richard E. Champlin, Chiara Bonini, Luigi Naldini, Edward J. Rebar, Philip D. Gregory, Michael C. Holmes, Laurence J.N. Cooper - Blood 2012 cited by 521

  6. Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

    Authors: Aaron D. Goldberg, Laura A. Banaszynski, Kyung‐Min Noh, Peter W. Lewis, Simon J. Elsaesser, Sonja C. Stadler, Scott Dewell, Martin J. Law, Xingyi Guo, Xuan Li, Duancheng Wen, Ariane Chapgier, Russell C. DeKelver, Jeffrey C. Miller, Ya-Li Lee, Elizabeth A. Boydston, Michael C. Holmes, Philip D. Gregory, John M. Greally, Shahin Rafii, Chingwen Yang, Peter Scambler, David Garrick, Richard J. Gibbons, Douglas R. Higgs, Ileana M. Cristea, Fyodor D. Urnov, Deyou Zheng, C. David Allis - Cell 2010 cited by 1,292

  7. Highly efficient endogenous human gene correction using designed zinc-finger nucleases

    Authors: Fyodor D. Urnov, Jeffrey C. Miller, Ya-Li Lee, Christian Beauséjour, Jeremy M. Rock, Sheldon Augustus, Andrew C. Jamieson, Matthew H. Porteus, Philip D. Gregory, Michael C. Holmes - Nature 2005 cited by 1,644

  8. In vivo partial cellular reprogramming enhances liver plasticity and regeneration

    Authors: Tomoaki Hishida, Mako Yamamoto, Yuriko Hishida-Nozaki, Changwei Shao, Ling Huang, Chao Wang, Kensaku Shojima, Yuan Xue, Yuqing Hang, Maxim N. Shokhirev, Sebastian Memczak, Sanjeeb Kumar Sahu, Fumiyuki Hatanaka, Rubén Rabadán-Ros, Matthew B. Maxwell, Jasmine Chavez, Yanjiao Shao, Hsin‐Kai Liao, Paloma Martínez‐Redondo, Isabel Guillen-Guillen, Reyna Hernández‐Benítez, Concepción Rodrı́guez Esteban, Jing Qu, Michael C. Holmes, Fei Yi, Raymond Hickey, Pedro Guillén García, Estrella Núñez‐Delicado, Antoni Castells, Josep M. Campistol, Yang Yu, Diana C. Hargreaves, Akihiro Asai, Pradeep Reddy, Guang‐Hui Liu, Juan Carlos Izpisúa Belmonte - Cell Reports 2022 cited by 106

  9. Toward eliminating HLA class I expression to generate universal cells from allogeneic donors

    Authors: Hiroki Torikai, Andreas Reik, Frank Soldner, Edus H. Warren, Carrie Yuen, Yuanyue Zhou, Denise L. Crossland, Helen Huls, Nicholas Littman, Ziying Zhang, Scott S. Tykodi, Partow Kebriaei, Dean A. Lee, Jeffrey C. Miller, Edward J. Rebar, Michael C. Holmes, Rudolf Jaenisch, Richard E. Champlin, Philip D. Gregory, Laurence J.N. Cooper - Blood 2013 cited by 305

  10. Persistent repression of tau in the brain using engineered zinc finger protein transcription factors

    Authors: Susanne Wegmann, Sarah L. DeVos, Bryan Zeitler, Kimberly Marlen, Rachel E. Bennett, Marta Pérez-Rando, Danny MacKenzie, Qi Yu, Caitlin Commins, Riley N. Bannon, Bianca T. Corjuc, Alison Chase, Lisa Diez, Hoang-Oanh B. Nguyen, Sarah J. Hinkley, Lei Zhang, Alicia Goodwin, Annemarie Ledeboer, Stephen C.-T. Lam, Irina Ankoudinova, Hung Tran, Nicholas A. Scarlott, Rainier Amora, Richard Surosky, Jeffrey C. Miller, Ashley B. Robbins, Edward J. Rebar, Fyodor D. Urnov, Michael C. Holmes, Amy M. Pooler, Brigit E. Riley, H. Steve Zhang, Bradley T. Hyman - Science Advances 2021 cited by 77

  11. Targeted genome editing in human repopulating haematopoietic stem cells

    Authors: Pietro Genovese, Giulia Schiroli, Giulia Escobar, Tiziano Di Tomaso, Claudia Firrito, Andrea Calabria, Davide Moi, Roberta Mazzieri, Chiara Bonini, Michael C. Holmes, Philip D. Gregory, Mirjam van der Burg, Bernhard Gentner, Eugenio Montini, Angelo Lombardo, Luigi Naldini - Nature 2014 cited by 565

  12. An improved zinc-finger nuclease architecture for highly specific genome editing

    Authors: Jeffrey C. Miller, Michael C. Holmes, Jianbin Wang, Dmitry Guschin, Ya-Li Lee, Igor Rupniewski, Christian Beauséjour, Adam James Waite, Nathaniel Wang, Kenneth A Kim, Philip D. Gregory, Carl O. Pabo, Edward J. Rebar - Nature Biotechnology 2007 cited by 1,047

  13. Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

    Authors: Elena Pérez, Jianbin Wang, Jeffrey C. Miller, Yann Jouvenot, Kenneth A Kim, Olga Liu, Nathaniel Wang, Gary Lee, Victor V. Bartsevich, Ya-Li Lee, Dmitry Guschin, Igor Rupniewski, Adam James Waite, Carmine Carpenito, Richard G. Carroll, Jordan S. Orange, Fyodor D. Urnov, Edward J. Rebar, Dale Ando, Philip D. Gregory, James L. Riley, Michael C. Holmes, Carl H. June - Nature Biotechnology 2008 cited by 999

  14. Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer

    Authors: Elena Provasi, Pietro Genovese, Angelo Lombardo, Zulma Magnani, Pei-Qi Liu, Andreas Reik, Victoria A. Chu, David E. Paschon, Lei Zhang, Jürgen Kuball, Barbara Camisa, Attilio Bondanza, Giulia Casorati, Maurilio Ponzoni, Fabio Ciceri, Claudio Bordignon, Philip D. Greenberg, Michael C. Holmes, Philip D. Gregory, Luigi Naldini, Chiara Bonini - Nature Medicine 2012 cited by 444

  15. In vivo genome editing of the albumin locus as a platform for protein replacement therapy

    Authors: Rajiv P. Sharma, Xavier M. Anguela, Yannick Doyon, Thomas Wechsler, Russell C. DeKelver, Scott Sproul, David E. Paschon, Jeffrey C. Miller, Robert J. Davidson, David A. Shivak, Shangzhen Zhou, Julianne Rieders, Philip D. Gregory, Michael C. Holmes, Edward J. Rebar, Katherine A. High - Blood 2015 cited by 298

  16. Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells

    Authors: Megan D. Hoban, Gregory J. Cost, Matthew Mendel, Zulema Romero, Michael L. Kaufman, Alok V. Joglekar, Michelle Ho, Dianne Lumaquin, David Gray, Georgia R. Lill, Aaron Cooper, Fabrizia Urbinati, Shantha Senadheera, Allen Zhu, Peiqi Liu, David E. Paschon, Lei Zhang, Edward J. Rebar, Andrew Wilber, Xiaoyan Wang, Philip D. Gregory, Michael C. Holmes, Andreas Reik, Roger P. Hollis, Donald B. Kohn - Blood 2015 cited by 320

  17. Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1

    Authors: Giulia Schiroli, Samuele Ferrari, Anthony Conway, Aurélien Jacob, Valentina Capo, Luisa Albano, Tiziana Plati, Maria Carmina Castiello, Francesca Sanvito, Andrew R. Gennery, Chiara Bovolenta, Rahul Palchaudhuri, David T. Scadden, Michael C. Holmes, Anna Villa, Giovanni Sitia, Angelo Lombardo, Pietro Genovese, Luigi Naldini - Science Translational Medicine 2017 cited by 216

  18. Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

    Authors: Angelo Lombardo, Pietro Genovese, Christian Beauséjour, Silvia Colleoni, Ya-Li Lee, Kenneth A Kim, Dale Ando, Fyodor D. Urnov, Cesare Galli, Philip D. Gregory, Michael C. Holmes, Luigi Naldini - Nature Biotechnology 2007 cited by 840

  19. Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34 + Hematopoietic Stem and Progenitor Cells

    Authors: Kai-Hsin Chang, Sarah E. Smith, Timothy M. Sullivan, Kai Chen, Qianhe Zhou, Jason A. West, Mei Liu, Yingchun Liu, Benjamin Vieira, Chao Sun, Vu Hong, Mingxuan Zhang, Yang Xiao, Andreas Reik, Fyodor D. Urnov, Edward J. Rebar, Michael C. Holmes, Olivier Danos, Haiyan Jiang, Siyuan Tan - Molecular Therapy — Methods & Clinical Development 2017 cited by 155

  20. Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor

    Authors: Rachel S. Leibman, Max W. Richardson, Christoph T. Ellebrecht, Colby R. Maldini, Joshua Glover, Anthony Secreto, Irina Kulikovskaya, Simon F. Lacey, Sarah R. Akkina, Yanjie Yi, Farida Shaheen, Jianbin Wang, Keith Dufendach, Michael C. Holmes, Ronald G. Collman, Aimee Payne, James L. Riley - PLoS Pathogens 2017 cited by 134

  21. Diversifying the structure of zinc finger nucleases for high-precision genome editing

    Authors: David E. Paschon, Stephanie Lussier, Tenzin Wangzor, Danny F. Xia, Patrick W. Li, Sarah J. Hinkley, Nicholas A. Scarlott, Stephen C.-T. Lam, Adam James Waite, Lynn Truong, Nimisha Gandhi, Bhakti N. Kadam, Deepak P. Patil, David A. Shivak, Gary K. Lee, Michael C. Holmes, Lei Zhang, Jeffrey C. Miller, Edward J. Rebar - Nature Communications 2019 cited by 128

  22. Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma

    Authors: Joal D. Beane, Gary Lee, Zhili Zheng, Matthew Mendel, Daniel Abate‐Daga, Mini Bharathan, Mary A. Black, Nimisha Gandhi, Zhiya Yu, Smita S. Chandran, Martin Giedlin, Dale Ando, Jeffrey C. Miller, David E. Paschon, Dmitry Guschin, Edward J. Rebar, Andreas Reik, Michael C. Holmes, Philip D. Gregory, Nicholas P. Restifo, Steven A. Rosenberg, Richard A. Morgan, Steven A. Feldman - Molecular Therapy 2015 cited by 114

  23. Non-viral Delivery of Zinc Finger Nuclease mRNA Enables Highly Efficient In Vivo Genome Editing of Multiple Therapeutic Gene Targets

    Authors: Anthony Conway, Matthew Mendel, Kenneth H. Kim, Kyle McGovern, A. A. Boyko, Lei Zhang, Jeffrey C. Miller, Russell C. DeKelver, David E. Paschon, Barbara L. Mui, Paulo J.C. Lin, Ying K. Tam, Chris Barbosa, T.E. Redelmeier, Michael C. Holmes, Gary Lee - Molecular Therapy 2019 cited by 94

  24. AAV2/6 Gene Therapy in a Murine Model of Fabry Disease Results in Supraphysiological Enzyme Activity and Effective Substrate Reduction

    Authors: Makiko Yasuda, Marshall W. Huston, Silvère Pagant, Lin Gan, Susan S. Martin, Scott Sproul, Daniel A. Richards, Stephen J. Ballaron, Khaled Hettini, Annemarie Ledeboer, Lillian Falese, Liching Cao, Yanmei Lu, Michael C. Holmes, Kathleen Meyer, Robert J. Desnick, Thomas Wechsler - Molecular Therapy — Methods & Clinical Development 2020 cited by 55