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Paul D. van Helden

Active 1987–2024

Also published as
Paul D van Helden
150
Papers
20,899
Citations
92
h-index
148
i10-index

Citations

Citations per year for Paul D. van Helden1989: 1 citations1990: 2 citations1991: 5 citations1992: 2 citations1993: 4 citations1994: 4 citations1995: 2 citations1996: 5 citations1997: 3 citations1998: 3 citations1999: 12 citations2000: 13 citations2001: 51 citations2002: 59 citations2003: 46 citations2004: 82 citations2005: 92 citations2006: 107 citations2007: 110 citations2008: 154 citations2009: 146 citations2010: 182 citations2011: 203 citations2012: 195 citations2013: 190 citations2014: 233 citations2015: 179 citations2016: 177 citations2017: 178 citations2018: 232 citations2019: 684 citations2020: 661 citations2021: 586 citations2022: 386 citations2023: 258 citations2024: 357 citations2025: 162 citations2026: 7 citations

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 1,564 citing papers, 17.5% of this breakdownUnited Kingdom: 885 citing papers, 9.9% of this breakdownSouth Africa: 854 citing papers, 9.6% of this breakdownChina: 403 citing papers, 4.5% of this breakdownIndia: 379 citing papers, 4.3% of this breakdownGermany: 346 citing papers, 3.9% of this breakdownFrance: 332 citing papers, 3.7% of this breakdownNetherlands: 313 citing papers, 3.5% of this breakdownSwitzerland: 292 citing papers, 3.3% of this breakdownAustralia: 223 citing papers, 2.5% of this breakdownCanada: 215 citing papers, 2.4% of this breakdownItaly: 194 citing papers, 2.2% of this breakdown
0%17.5%Other 32.7%

Institutions

Fields

  • Medicine74.6%
  • Biochemistry, Genetics and Molecular Biology12.3%
  • Immunology and Microbiology6.4%
  • Agricultural and Biological Sciences1.2%
  • Pharmacology, Toxicology and Pharmaceutics1%
  • Computer Science0.9%
  • Other3.6%

Topics

  • Tuberculosis Research and Epidemiology23.5%
  • Mycobacterium research and diagnosis13%
  • Infectious Diseases and Tuberculosis5%
  • Diagnosis and treatment of tuberculosis4.5%
  • Pneumocystis jirovecii pneumonia detection and treatment2.7%
  • Pneumonia and Respiratory Infections2.4%
  • Other48.9%

Coauthors

All papers

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  1. The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

    Authors: Keertan Dheda, Tawanda Gumbo, Gary Maartens, Kelly E. Dooley, Ruth McNerney, Megan Murray, Jennifer Furin, Edward A. Nardell, Leslie London, Erica Lessem, Grant Theron, Paul D. van Helden, Stefan Niemann, Matthias Merker, David W. Dowdy, Annelies Van Rie, G. G. Siu, Jotam G. Pasipanodya, Camilla Rodrigues, Taane G. Clark, F A Sirgel, Aliasgar Esmail, Hsien-Ho Lin, Sachin Atre, H. Simon Schaaf, Kwok Chiu Chang, Christoph Lange, Payam Nahid, Zarir Udwadia, C. Robert Horsburgh, Gavin Churchyard, Dick Menzies, Anneke C. Hesseling, Eric Nuermberger, Helen McIlleron, Kevin P. Fennelly, Eric Goemaere, Ernesto Jaramillo, Marcus Low, Carolina Morán Jara, Nesri Padayatchi, Robin M. Warren - The Lancet Respiratory Medicine 2017 cited by 679

  2. Evolution of rifampicin treatment for tuberculosis

    Authors: Melanie Grobbelaar, Gail Louw, Samantha L. Sampson, Paul D. van Helden, Peter R. Donald, Robin M. Warren - Infection Genetics and Evolution 2019 cited by 125

  3. Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis

    Authors: Francesc Coll, Jody Phelan, Grant Hill-Cawthorne, Mridul Nair, Kim Mallard, Shahjahan Ali, Abdallah M. Abdallah, Saad Alghamdi, Mona Alsomali, Abdallah O. Ahmed, Stephanie Portelli, Yaa Oppong, Adriana Alves, Theolis Barbosa, Susana Campino, Maxine Caws, Anirvan Chatterjee, Amelia C. Crampin, Keertan Dheda, Nicholas Furnham, Judith R. Glynn, Louis Grandjean, Dang Minh Ha, Rumina Hasan, Zahra Hasan, Martin L. Hibberd, Moses Joloba, Edward C. Jones‐López, Tomoshige Matsumoto, Anabela Miranda, David Moore, Nora Mocillo, Stefan Panaiotov, Julian Parkhill, Carlos Penha‐Gonçalves, João Perdigão, Isabel Portugal, Zineb Rchiad, Jaime Robledo, Patricia Sheen, Nashwa Talaat Shesha, F A Sirgel, Christophe Sola, Erivelton Oliveira Sousa, Elizabeth M. Streicher, Paul D. van Helden, Miguel Viveiros, Robin M. Warren, Ruth McNerney, Arnab Pain, Taane G. Clark - Nature Genetics 2018 cited by 428

  4. Bacterial and host determinants of cough aerosol culture positivity in patients with drug-resistant versus drug-susceptible tuberculosis

    Authors: Grant Theron, Jason Limberis, Rouxjeane Venter, Lucas Smith, Elize Pietersen, Aliasgar Esmail, Greg Calligaro, Julian te Riele, Marianna de Kock, Paul D. van Helden, Tawanda Gumbo, Taane G. Clark, Kevin P. Fennelly, Robin M. Warren, Keertan Dheda - Nature Medicine 2020 cited by 75

  5. Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13

    Authors: Anup Aggarwal, Maloy Kumar Parai, N.D. Shetty, Deeann Wallis, Lisa K. Woolhiser, Courtney Hastings, Noton K. Dutta, Stacy Galaviz, Ramesh Dhakal, Rupesh Shrestha, Shoko Wakabayashi, Chris Walpole, David J. Matthews, David Floyd, Paul Scullion, Jennifer Riley, Ola Epemolu, Suzanne Norval, Thomas Snavely, Gregory T. Robertson, Eric J. Rubin, Thomas R. Ioerger, F A Sirgel, Ruben van der Merwe, Paul D. van Helden, Peter M. Keller, Erik C. Böttger, Petros C. Karakousis, Anne J. Lenaerts, James C. Sacchettini - Cell 2017 cited by 185

  6. Detection of tuberculosis by automatic cough sound analysis

    Authors: Gert Hendrik Renier Botha, Grant Theron, Robin M. Warren, Marisa Klopper, Keertan Dheda, Paul D. van Helden, Thomas Niesler - Physiological Measurement 2018 cited by 127

  7. ZoonoticMycobacterium bovis–induced Tuberculosis in Humans

    Authors: Borna Müller, Salome Dürr, Silvia Alonso, Jan Hattendorf, Cláudio João Mourão Laisse, Sven D.C. Parsons, Paul D. van Helden, Jakob Zinsstag - Emerging infectious diseases 2013 cited by 364

  8. Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions.

    Authors: Nicolaas C. Gey van Pittius, Samantha L. Sampson, Hyeyoung Lee, Yeun Kim, Paul D. van Helden, Robin M. Warren - BMC Evolutionary Biology 2006 cited by 429

  9. Anaerobe-enriched gut microbiota predicts pro-inflammatory responses in pulmonary tuberculosis

    Authors: C Naidoo, Georgina Nyawo, Imran Sulaiman, Benjamin G. Wu, Carolin T. Turner, Kevin Bu, Zaida Palmer, Yonghua Li, Byron W P Reeve, Suventha Moodley, Jennifer G. Jackson, Jason Limberis, Andreas H. Diacon, Paul D. van Helden, José C. Clemente, Robin M. Warren, Mahdad Noursadeghi, Leopoldo N. Segal, Grant Theron - EBioMedicine 2021 cited by 54

  10. Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population genetics and epidemiology

    Authors: Karine Brudey, Jeffrey Driscoll, Leen Rigouts, Wolfgang M. Prodinger, Andrea Gori, Sahal Al‐Hajoj, Caroline Allix, Liselotte Aristimuño, Jyoti Arora, Viesturs Baumanis, Lothar Binder, Patrícia Izquierdo Cafrune, Angel Cataldi, Soonfatt Cheong, Roland Diel, C Ellermeier, Jason T. Evans, Maryse Fauville‐Dufaux, Séverine Ferdinand, Darı́o Garcı́a de Viedma, Carlo Garzelli, Lidia Gazzola, Harrison Magdinier Gomes, M Cristina Guttierez, Peter M. Hawkey, Paul D. van Helden, Gurujaj V Kadival, Barry N. Kreiswirth, Kristin Kremer, Milan Kubín, Savita P Kulkarni, Benjamin Liens, Troels Lillebæk, Ho Minh Ly, Carlos Martı́n, Christian Martin, Igor Mokrousov, О. В. Нарвская, Yun Fong Ngeow, Ludmilla Naumann, Stefan Niemann, Ida Parwati, Zeaur Rahim, Voahangy Rasolofo-Razanamparany, T Rasolonavalona, Maria Lúcia Rosa Rossetti, Sabine Rüsch–Gerdes, Anna Sajduda, Sofía Samper, I. G. Shemyakin, Urvashi B. Singh, Ákos Somoskövi, Robin Skuce, Dick van Soolingen, Elizabeth M. Streicher, Philip Noël Suffys, Enrico Tortoli, Tatjana Tračevska, Véronique Vincent, Tommie C. Victor, Robin M. Warren, Sook Fan Yap, Khadiza Zaman, Françoise Portaels, Nalin Rastogi, Christophe Sola - BMC Microbiology 2006 cited by 1,035

  11. The Temporal Dynamics of Relapse and Reinfection Tuberculosis After Successful Treatment: A Retrospective Cohort Study

    Authors: Florian M. Marx, Rory Dunbar, Donald A. Enarson, Brian Williams, Robin M. Warren, Gian van der Spuy, Paul D. van Helden, Nulda Beyers - Clinical Infectious Diseases 2014 cited by 147

  12. Xpert MTB/RIF Ultra and Xpert MTB/RIF for diagnosis of tuberculosis in an HIV-endemic setting with a high burden of previous tuberculosis: a two-cohort diagnostic accuracy study

    Authors: Hridesh Mishra, Byron W P Reeve, Zaida Palmer, Judy Caldwell, Tania Dolby, C Naidoo, Jennifer G. Jackson, Samuel G. Schumacher, Claudia M. Denkinger, Andreas H. Diacon, Paul D. van Helden, Florian M. Marx, Robin M. Warren, Grant Theron - The Lancet Respiratory Medicine 2020 cited by 98

  13. Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study

    Authors: Josephine M. Bryant, Simon R. Harris, Julian Parkhill, Rodney Dawson, Andreas H. Diacon, Paul D. van Helden, Alexander S. Pym, Aziah Ahmad Mahayiddin, Charoen Chuchottaworn, Ian Sanne, Cheryl Louw, Martin J. Boeree, Michael Höelscher, Timothy D. McHugh, Anna L. C. Bateson, Robert D. Hunt, Solomon Mwaigwisya, Laura Wright, Stephen H. Gillespie, Stephen D. Bentley - The Lancet Respiratory Medicine 2013 cited by 218

  14. Drug-Penetration Gradients Associated with Acquired Drug Resistance in Patients with Tuberculosis

    Authors: Keertan Dheda, Laura Lenders, Gesham Magombedze, Shashikant Srivastava, Prithvi Raj, Erland Arning, Paula Ashcraft, Teodoro Bottiglieri, Helen Wainwright, Timothy Pennel, Anthony Linegar, Loven Moodley, Anil Pooran, Jotam G. Pasipanodya, Frederick A. Sirgel, Paul D. van Helden, Edward K. Wakeland, Robin M. Warren, Tawanda Gumbo - American Journal of Respiratory and Critical Care Medicine 2018 cited by 163

  15. Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB

    Authors: Novel N. Chegou, Jayne S. Sutherland, Stephanus T. Malherbe, Amelia C. Crampin, Paul L. A. M. Corstjens, Annemieke Geluk, Harriet Mayanja‐Kizza, André G. Loxton, Gian van der Spuy, Kim Stanley, Leigh A. Kotzé, Marieta van der Vyver, Ida Rosenkrands, Martin Kidd, Paul D. van Helden, Hazel M. Dockrell, Tom H. M. Ottenhoff, Stefan H. E. Kaufmann, Gerhard Walzl - Thorax 2016 cited by 158

  16. The influence of dose and N-acetyltransferase-2 (NAT2) genotype and phenotype on the pharmacokinetics and pharmacodynamics of isoniazid

    Authors: Peter R. Donald, D. P. Parkin, H. I. Seifart, H. Simon Schaaf, Paul D. van Helden, Cedric J. Werely, Frederick A. Sirgel, Amour Venter, J. S. Maritz - European Journal of Clinical Pharmacology 2007 cited by 99

  17. Putative Compensatory Mutations in the rpoC Gene of Rifampin-Resistant Mycobacterium tuberculosis Are Associated with Ongoing Transmission

    Authors: Margaretha de Vos, Borna Müller, Sònia Borrell, Philippa A. Black, Paul D. van Helden, Robin M. Warren, Sébastien Gagneux, T. C. Victor - Antimicrobial Agents and Chemotherapy 2012 cited by 220

  18. Mutation rate and the emergence of drug resistance in Mycobacterium tuberculosis

    Authors: Marieta McGrath, Nicolaas C. Gey van Pittius, Paul D. van Helden, Robin M. Warren, Digby F. Warner - Journal of Antimicrobial Chemotherapy 2013 cited by 166

  19. Energy Metabolism and Drug Efflux in Mycobacterium tuberculosis

    Authors: Philippa A. Black, Robin M. Warren, Gail Louw, Paul D. van Helden, Thomas C. Victor, Bavesh D Kana - Antimicrobial Agents and Chemotherapy 2014 cited by 142

  20. Glutamate dehydrogenase and glutamine synthetase are regulated in response to nitrogen availability in Myocbacterium smegmatis

    Authors: Catriona Harper, Don Hayward, Martin Kidd, Ian Wiid, Paul D. van Helden - BMC Microbiology 2010 cited by 84

  21. Local Ancestry Adjusted Allelic Association Analysis Robustly Captures Tuberculosis Susceptibility Loci

    Authors: Yolandi Swart, Caitlin Uren, Paul D. van Helden, Eileen G. Hoal, Marlo Möller - Frontiers in Genetics 2021 cited by 30

  22. Proportion of tuberculosis transmission that takes place in households in a high-incidence area

    Authors: Suzanne Verver, Robin M. Warren, Zahn Münch, Madalene Richardson, Gian van der Spuy, Martien W. Borgdorff, Marcel A. Behr, Nulda Beyers, Paul D. van Helden - The Lancet 2004 cited by 310

  23. Mixed-Strain Mycobacterium tuberculosis Infections and the Implications for Tuberculosis Treatment and Control

    Authors: Ted Cohen, Paul D. van Helden, Douglas Wilson, Caroline Colijn, Megan McLaughlin, Ibrahim Abubakar, Robin M. Warren - Clinical Microbiology Reviews 2012 cited by 212

  24. Efflux pump inhibitors: targeting mycobacterial efflux systems to enhance TB therapy

    Authors: Caroline M. Pule, Samantha L. Sampson, Robin M. Warren, Philippa A. Black, Paul D. van Helden, Tommie C. Victor, Gail Louw - Journal of Antimicrobial Chemotherapy 2015 cited by 158