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William R. Schief

Active 1996–2026

135
Papers
22,818
Citations
79
h-index
126
i10-index

Citations

Citations per year for William R. Schief1981: 1 citations1988: 1 citations1995: 1 citations1997: 3 citations1998: 5 citations2000: 2 citations2001: 10 citations2002: 7 citations2003: 11 citations2004: 21 citations2005: 40 citations2006: 16 citations2007: 16 citations2008: 26 citations2009: 19 citations2010: 44 citations2011: 110 citations2012: 168 citations2013: 275 citations2014: 212 citations2015: 273 citations2016: 365 citations2017: 363 citations2018: 407 citations2019: 955 citations2020: 1,098 citations2021: 1,111 citations2022: 886 citations2023: 822 citations2024: 1,333 citations2025: 842 citations2026: 47 citations1982–1987: no citations, so these years are not shown1989–1994: no citations, so these years are not shown1996: no citations, so this year is not shown1999: no citations, so this year is not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 2,662 citing papers, 38.2% of this breakdownChina: 607 citing papers, 8.7% of this breakdownUnited Kingdom: 468 citing papers, 6.7% of this breakdownGermany: 345 citing papers, 4.9% of this breakdownFrance: 231 citing papers, 3.3% of this breakdownNetherlands: 231 citing papers, 3.3% of this breakdownCanada: 228 citing papers, 3.3% of this breakdownSwitzerland: 211 citing papers, 3% of this breakdownAustralia: 152 citing papers, 2.2% of this breakdownItaly: 134 citing papers, 1.9% of this breakdownSouth Africa: 128 citing papers, 1.8% of this breakdownSweden: 117 citing papers, 1.7% of this breakdown
0%38.2%Other 21%

Institutions

Fields

  • Immunology and Microbiology33.7%
  • Medicine29.3%
  • Biochemistry, Genetics and Molecular Biology28%
  • Pharmacology, Toxicology and Pharmaceutics2.1%
  • Computer Science1.1%
  • Materials Science1.1%
  • Other4.7%

Topics

  • HIV Research and Treatment8.8%
  • Monoclonal and Polyclonal Antibodies Research6.9%
  • Immunotherapy and Immune Responses5.3%
  • Immune Cell Function and Interaction4.8%
  • vaccines and immunoinformatics approaches4.5%
  • SARS-CoV-2 and COVID-19 Research4.3%
  • Other65.4%

Coauthors

All papers

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  1. Macromolecular modeling and design in Rosetta: recent methods and frameworks

    Authors: Julia Koehler Leman, Brian D. Weitzner, Steven M. Lewis, Jared Adolf‐Bryfogle, Nawsad Alam, Rebecca F. Alford, Melanie L. Aprahamian, David Baker, Kyle A. Barlow, Patrick Barth, Benjamin Basanta, Brian J. Bender, Kristin Blacklock, Jaume Bonet, Scott E. Boyken, Phil Bradley, Chris Bystroff, Patrick Conway, Seth Cooper, Bruno E. Correia, Brian Coventry, Rhiju Das, René M. de Jong, Frank DiMaio, Lorna Dsilva, Roland L. Dunbrack, Alexander S. Ford, Brandon Frenz, Darwin Fu, Caleb Geniesse, Lukasz Goldschmidt, Ragul Gowthaman, Jeffrey J. Gray, Dominik Gront, Sharon L. Guffy, Scott Horowitz, Po‐Ssu Huang, Thomas Huber, Timothy M. Jacobs, Jeliazko R. Jeliazkov, David K. Johnson, Kalli Kappel, John Karanicolas, Hamed Khakzad, Karen R. Khar, Sagar D. Khare, Firas Khatib, Alisa Khramushin, Indigo C. King, Robert Kleffner, Brian Koepnick, Tanja Kortemme, Georg Kuenze, Brian Kuhlman, Daisuke Kuroda, Jason W. Labonte, Jason Lai, Gideon Lapidoth, Andrew Leaver‐Fay, Steffen Lindert, Thomas W. Linsky, Nir London, Joseph H. Lubin, Sergey Lyskov, Jack B. Maguire, Lars Malmström, Enrique Marcos, Orly Marcu, Nicholas Marze, Jens Meiler, Rocco Moretti, Vikram Khipple Mulligan, Santrupti Nerli, Christoffer Norn, Shane Ó’Conchúir, Noah Ollikainen, Sergey Ovchinnikov, Michael S. Pacella, Xingjie Pan, Hahnbeom Park, Ryan E. Pavlovicz, Manasi A. Pethe, Brian G. Pierce, Kala Bharath Pilla, Barak Raveh, P. Douglas Renfrew, Shourya S. Roy Burman, Aliza B. Rubenstein, Marion F. Sauer, Andreas Scheck, William R. Schief, Ora Schueler‐Furman, Yuval Sedan, Alexander M. Sevy, Nikolaos G. Sgourakis, Lei Shi, Justin B. Siegel, Daniel‐Adriano Silva, Shannon T. Smith, Yifan Song and 8 more - Nature Methods 2020 cited by 923

  2. Vaccination induces HIV broadly neutralizing antibody precursors in humans

    Authors: David J. Leggat, Kristen W. Cohen, Jordan R. Willis, William J. Fulp, Allan C. deCamp, Oleksandr Kalyuzhniy, Christopher A. Cottrell, Sergey Menis, Greg Finak, Lamar Ballweber-Fleming, Abhinaya Srikanth, Jason R. Plyler, Torben Schiffner, Alessia Liguori, Farhad Rahaman, Angela Lombardo, Vincent Philiponis, Rachael E. Whaley, Aaron Seese, Joshua Brand, Alexis M. Ruppel, Wesley Hoyland, Nicole L. Yates, LaTonya D. Williams, Kelli Greene, Hongmei Gao, Celia R. Mahoney, Martin Corcoran, Alberto Cagigi, Alison Taylor, David M. Brown, David R. Ambrozak, Troy Sincomb, Xiaozhen Hu, Ryan Tingle, Erik Georgeson, Saman Eskandarzadeh, Nushin Alavi, Danny Lu, Tina-Marie Mullen, Michael Kubitz, Bettina Gröschel, Janine Maenza, Orpheus Kolokythas, Nadia J. Khati, Jeffrey M. Bethony, Shane Crotty, Mario Roederer, Gunilla B. Karlsson Hedestam, Georgia D. Tomaras, David C. Montefiori, David Diemert, Richard A. Koup, Dagna Laufer, M. Juliana McElrath, Adrian B. McDermott, William R. Schief - Science 2022 cited by 272

  3. Role of nanoscale antigen organization on B-cell activation probed using DNA origami

    Authors: Rémi Veneziano, Tyson J. Moyer, Matthew B. Stone, Eike‐Christian Wamhoff, Benjamin J. Read, Sayak Mukherjee, Tyson R. Shepherd, Jayajit Das, William R. Schief, Darrell J. Irvine, Mark Bathe - Nature Nanotechnology 2020 cited by 442

  4. Long-primed germinal centres with enduring affinity maturation and clonal migration

    Authors: Jeong Hyun Lee, Henry J. Sutton, Christopher A. Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M. Sewall, Rebecca Nedellec, Catherine Nakao, Murillo Silva, Sara T. Richey, Jonathan L. Torres, Wen-Hsin Lee, Erik Georgeson, Michael Kubitz, Sam Hodges, Tina-Marie Mullen, Yumiko Adachi, Kimberly M. Cirelli, Amitinder Kaur, Carolina Allers, Marissa Fahlberg, Brooke Grasperge, Jason Dufour, Faith Schiro, Pyone P. Aye, Oleksandr Kalyuzhniy, Alessia Liguori, Diane G. Carnathan, Guido Silvestri, Xiaoying Shen, David C. Montefiori, Ronald S. Veazey, Andrew B. Ward, Lars Hangartner, Dennis R. Burton, Darrell J. Irvine, William R. Schief, Shane Crotty - Nature 2022 cited by 192

  5. Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance

    Authors: Kimberly M. Cirelli, Diane G. Carnathan, Bartek Nogal, Jacob T. Martin, Oscar L. Rodriguez, Amit A. Upadhyay, Chiamaka A. Enemuo, Etse H. Gebru, Yury Choe, Federico Viviano, Catherine Nakao, Matthias Pauthner, Samantha Reiss, Christopher A. Cottrell, Melissa Smith, Raiza Bastidas, William Gibson, Amber Wolabaugh, Mariane B. Melo, Benjamin Cossette, Venkatesh Kumar, Nirav Patel, Talar Tokatlian, Sergey Menis, Daniel W. Kulp, Dennis R. Burton, Ben Murrell, William R. Schief, Steven E. Bosinger, Andrew B. Ward, Corey T. Watson, Guido Silvestri, Darrell J. Irvine, Shane Crotty - Cell 2019 cited by 470

  6. Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

    Authors: Xueling Wu, Zhi-Yong Yang, Yuxing Li, Carl-Magnus Hogerkorp, William R. Schief, Michael S. Seaman, Tongqing Zhou, Stephen D. Schmidt, Lan Wu, Ling Xu, Nancy S. Longo, Krisha McKee, Sijy O’Dell, Mark K. Louder, Diane Wycuff, Yu Feng, Martha Nason, Nicole A. Doria‐Rose, Mark Connors, Peter D. Kwong, Mario Roederer, Richard T. Wyatt, Gary J. Nabel, John R. Mascola - Science 2010 cited by 1,802

  7. Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

    Authors: Joseph G. Jardine, Jean‐Philippe Julien, Sergey Menis, Takayuki Ota, Oleksandr Kalyuzhniy, Andrew T. McGuire, Devin Sok, Po‐Ssu Huang, Skye MacPherson, Meaghan Jones, Travis Nieusma, John C. Mathison, David Baker, Andrew B. Ward, Dennis R. Burton, Leonidas Stamatatos, David Nemazee, Ian A. Wilson, William R. Schief - Science 2013 cited by 822

  8. Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo

    Authors: Yu Kato, Robert Abbott, Brian L. Freeman, Sonya Haupt, Bettina Gröschel, Murillo Silva, Sergey Menis, Darrell J. Irvine, William R. Schief, Shane Crotty - Immunity 2020 cited by 281

  9. RosettaAntibodyDesign (RAbD): A general framework for computational antibody design

    Authors: Jared Adolf-Bryfogle, Oleksandr Kalyuzhniy, Michael Kubitz, Brian D. Weitzner, Xiaozhen Hu, Yumiko Adachi, William R. Schief, Roland L. Dunbrack Jr. - PLoS Computational Biology, PLoS Comput. Biol. 2008 cited by 230

  10. A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses

    Authors: Jon M. Steichen, Ying‐Cing Lin, Colin Havenar‐Daughton, Simone Pecetta, Gabriel Ozorowski, Jordan R. Willis, Laura Toy, Devin Sok, Alessia Liguori, Sven Kratochvil, Jonathan L. Torres, Oleksandr Kalyuzhniy, Eleonora Melzi, Daniel W. Kulp, Sebastian Raemisch, Xiaozhen Hu, Steffen M. Bernard, Erik Georgeson, Nicole Phelps, Yumiko Adachi, Michael Kubitz, Elise Landais, Jeffrey C. Umotoy, Amanda M. Robinson, Bryan Briney, Ian A. Wilson, Dennis R. Burton, Andrew B. Ward, Shane Crotty, Facundo D. Batista, William R. Schief - Science 2019 cited by 284

  11. A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity

    Authors: Murillo Silva, Yu Kato, Mariane B. Melo, Ivy Phung, Brian L. Freeman, Zhong‐Ming Li, Kangsan Roh, Jan Willem van Wijnbergen, Hannah C. Watkins, Chiamaka A. Enemuo, Brittany L. Hartwell, Jason Y.H. Chang, Shuhao Xiao, Kristen A. Rodrigues, Kimberly M. Cirelli, Na Li, Sonya Haupt, Aereas Aung, Benjamin Cossette, Wuhbet Abraham, Swati Kataria, Raiza Bastidas, Jinal N. Bhiman, Caitlyn Linde, Nathaniel I. Bloom, Bettina Gröschel, Erik Georgeson, Nicole Phelps, Ayush Thomas, Julia Bals, Diane G. Carnathan, Daniel Lingwood, Dennis R. Burton, Galit Alter, Timothy P. Padera, Angela M. Belcher, William R. Schief, Guido Silvestri, Ruth M. Ruprecht, Shane Crotty, Darrell J. Irvine - Science Immunology 2021 cited by 174

  12. HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen

    Authors: Joseph G. Jardine, Daniel W. Kulp, Colin Havenar‐Daughton, Anita Sarkar, Bryan Briney, Devin Sok, Fabian Sesterhenn, June Ereño‐Orbea, Oleksandr Kalyuzhniy, Isaiah Deresa, Xiaozhen Hu, Skye Spencer, Meaghan Jones, Erik Georgeson, Yumiko Adachi, Michael Kubitz, Allan C. deCamp, Jean‐Philippe Julien, Ian A. Wilson, Dennis R. Burton, Shane Crotty, William R. Schief - Science 2016 cited by 483

  13. HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

    Authors: Jon M. Steichen, Daniel W. Kulp, Talar Tokatlian, Amelia Escolano, Pia Dosenovic, Robyn L. Stanfield, Laura E. McCoy, Gabriel Ozorowski, Xiaozhen Hu, Oleksandr Kalyuzhniy, Bryan Briney, Torben Schiffner, Fernando Garcés, Natalia T. Freund, Alexander D. Gitlin, Sergey Menis, Erik Georgeson, Michael Kubitz, Yumiko Adachi, Meaghan Jones, Andrew A. Mutafyan, Dong Soo Yun, Christian T. Mayer, Andrew B. Ward, Dennis R. Burton, Ian A. Wilson, Darrell J. Irvine, M C Nussenzweig, William R. Schief - Immunity 2016 cited by 445

  14. Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

    Authors: Jeroen M. J. Tas, Jahyun Koo, Ying‐Cing Lin, Zhenfei Xie, Jon M. Steichen, Abigail M. Jackson, Blake M. Hauser, Xuesong Wang, Christopher A. Cottrell, Jonathan L. Torres, John E. Warner, Kathrin H. Kirsch, Stephanie R. Weldon, Bettina Gröschel, Bartek Nogal, Gabriel Ozorowski, Sandhya Bangaru, Nicole Phelps, Yumiko Adachi, Saman Eskandarzadeh, Michael Kubitz, Dennis R. Burton, Daniel Lingwood, Aaron G. Schmidt, Usha Nair, Andrew B. Ward, William R. Schief, Facundo D. Batista - Immunity 2022 cited by 157

  15. Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens

    Authors: Robert Abbott, Jeong Hyun Lee, Sergey Menis, Patrick Skog, Meghan Rossi, Takayuki Ota, Daniel W. Kulp, Deepika Bhullar, Oleksandr Kalyuzhniy, Colin Havenar‐Daughton, William R. Schief, David Nemazee, Shane Crotty - Immunity 2017 cited by 367

  16. Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers

    Authors: Talar Tokatlian, Benjamin J. Read, Christopher A. Jones, Daniel W. Kulp, Sergey Menis, Jason Y.H. Chang, Jon M. Steichen, Sudha Kumari, Joel D. Allen, Eric L. Dane, Alessia Liguori, Maya Sangesland, Daniel Lingwood, Max Crispin, William R. Schief, Darrell J. Irvine - Science 2018 cited by 312

  17. Engineered immunogen binding to alum adjuvant enhances humoral immunity

    Authors: Tyson J. Moyer, Yu Kato, Wuhbet Abraham, Jason Y.H. Chang, Daniel W. Kulp, Nicki Watson, Hannah L. Turner, Sergey Menis, Robert Abbott, Jinal N. Bhiman, Mariane B. Melo, Hayley Simon, Sara Herrera de la Mata, Shu Liang, Grégory Seumois, Yash Agarwal, Na Li, Dennis R. Burton, Andrew B. Ward, William R. Schief, Shane Crotty, Darrell J. Irvine - Nature Medicine 2020 cited by 267

  18. Proof of principle for epitope-focused vaccine design

    Authors: Bruno E. Correia, John T. Bates, Rebecca J. Loomis, Gretchen Baneyx, Chris Carrico, Joseph G. Jardine, Peter B. Rupert, Colin Correnti, Oleksandr Kalyuzhniy, Vinayak Vittal, Mary J. Connell, Eric Stevens, Alexandria Schroeter, Man Chen, Skye MacPherson, Andreia M. Serra, Yumiko Adachi, Margaret A. Holmes, Yuxing Li, Rachel E. Klevit, Barney S. Graham, Richard T. Wyatt, David Baker, Roland K. Strong, James E. Crowe, Philip R. Johnson, William R. Schief - Nature, Nat. 2011 cited by 587

  19. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen

    Authors: Joseph G. Jardine, Takayuki Ota, Devin Sok, Matthias Pauthner, Daniel W. Kulp, Oleksandr Kalyuzhniy, Patrick Skog, Theresa C. Thinnes, Deepika Bhullar, Bryan Briney, Sergey Menis, Meaghan Jones, Mike Kubitz, Skye Spencer, Yumiko Adachi, Dennis R. Burton, William R. Schief, David Nemazee - Science 2015 cited by 439

  20. RosettaRemodel: A Generalized Framework for Flexible Backbone Protein Design

    Authors: Po‐Ssu Huang, Yih‐En Andrew Ban, Florian Richter, Ingemar André, Robert M. Vernon, William R. Schief, David Baker - PLoS ONE 2011 cited by 414

  21. Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

    Authors: Ming Tian, Cheng Cheng, Xuejun Chen, Hongying Duan, Hwei-Ling Cheng, Mai N. Dao, Zizhang Sheng, Michael T. Kimble, Lingshu Wang, Sherry Lin, Stephen D. Schmidt, Zhou Du, Michael Joyce, Yiwei Chen, Brandon J. DeKosky, Yimin Chen, Erica Normandin, Elizabeth Cantor, Rita E. Chen, Nicole A. Doria‐Rose, Yi Zhang, Wei Shi, Wing‐Pui Kong, Misook Choe, Amy R. Henry, Farida Laboune, Ivelin S. Georgiev, Pei-Yi Huang, Suvi Jain, Andrew T. McGuire, Eric Georgeson, Sergey Menis, Daniel C. Douek, William R. Schief, Leonidas Stamatatos, Peter D. Kwong, Lawrence Shapiro, Barton F. Haynes, John R. Mascola, Frederick W. Alt - Cell 2016 cited by 258

  22. mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies

    Authors: Zhenfei Xie, Ying‐Cing Lin, Jon M. Steichen, Gabriel Ozorowski, Sven Kratochvil, Rashmi Ray, Jonathan L. Torres, Alessia Liguori, Oleksandr Kalyuzhniy, Xuesong Wang, John E. Warner, Stephanie R. Weldon, Gordon Dale, Kathrin H. Kirsch, Usha Nair, Sabyasachi Baboo, Erik Georgeson, Yumiko Adachi, Michael Kubitz, Abigail M. Jackson, Sara T. Richey, Reid M. Volk, Jeong Hyun Lee, Jolene K. Diedrich, Thavaleak Prum, Samantha Falcone, Sunny Himansu, Andrea Carfı́, John R. Yates, James C. Paulson, Devin Sok, Andrew B. Ward, William R. Schief, Facundo D. Batista - Science 2024 cited by 66

  23. Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates

    Authors: Jon M. Steichen, Ivy Phung, Eugenia Salcedo, Gabriel Ozorowski, Jordan R. Willis, Sabyasachi Baboo, Alessia Liguori, Christopher A. Cottrell, Jonathan L. Torres, Patrick Madden, M. Krystal, Henry J. Sutton, Jeong Hyun Lee, Oleksandr Kalyuzhniy, Joel D. Allen, Oscar L. Rodriguez, Yumiko Adachi, Tina-Marie Mullen, Erik Georgeson, Michael Kubitz, Alison Burns, Shawn Barman, Rohini Mopuri, Amanda Metz, Tasha K. Altheide, Jolene K. Diedrich, Swati Saha, Kaitlyn Shields, Steven E. Schultze, Melissa Smith, Torben Schiffner, Dennis R. Burton, Corey T. Watson, Steven E. Bosinger, Max Crispin, John R. Yates, James C. Paulson, Andrew B. Ward, Devin Sok, Shane Crotty, William R. Schief - Science 2024 cited by 65

  24. A first-in-human germline-targeting HIV nanoparticle vaccine induced broad and publicly targeted helper T cell responses

    Authors: Kristen W. Cohen, Stephen C. De Rosa, William J. Fulp, Allan C. deCamp, Andrew Fioré-Gartland, Celia R. Mahoney, Sarah Furth, J. G. Donahue, Rachael E. Whaley, Lamar Ballweber-Fleming, Aaron Seese, Katharine V. Schwedhelm, Daniel E. Geraghty, Greg Finak, Sergey Menis, David J. Leggat, Farhad Rahaman, Angela Lombardo, Bhavesh Borate, Vincent Philiponis, Janine Maenza, David Diemert, Orpheus Kolokythas, Nadia J. Khati, Jeffrey M. Bethony, Ollivier Hyrien, Dagna Laufer, Richard A. Koup, Adrian B. McDermott, William R. Schief, M. Juliana McElrath - Science Translational Medicine 2023 cited by 70