Brian Kuhlman
1998–2024 年に発表
- 94
- 論文数
- 21,124
- 被引用数
- 69
- h 指数
- 92
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology60.9%
- Medicine13.9%
- Neuroscience7.3%
- Computer Science4.6%
- Agricultural and Biological Sciences2.9%
- Materials Science2.9%
- その他7.5%
トピック
- Protein Structure and Dynamics10.8%
- RNA and protein synthesis mechanisms5.6%
- Enzyme Structure and Function5.3%
- Computational Drug Discovery Methods3.6%
- Monoclonal and Polyclonal Antibodies Research3%
- Ubiquitin and proteasome pathways2.5%
- その他69.2%
共著者
- David Baker18
- Andrew Leaver‐Fay14
- Steven M. Lewis11
- Jeffrey J. Gray10
- Sergey Lyskov9
- Klaus M. Hahn8
- Tanja Kortemme8
- Hayretin Yumerefendi7
- James E. Bear7
- P. Douglas Renfrew7
- Seth P. Zimmerman7
- Bryan S. Der6
- Jack B. Maguire6
- Jack Snoeyink6
- Joseph S. Harrison6
- Rhiju Das6
- Richard Bonneau6
- James J. Havranek5
- Philip Bradley5
- Ron Jacak5
- Stephan T. Kudlacek5
- Brian D. Weitzner4
- David E. Kim4
- Frank DiMaio4
全論文
- The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design
著者: Rebecca F. Alford, Andrew Leaver‐Fay, Jeliazko R. Jeliazkov, Matthew J. O’Meara, Frank DiMaio, Hahnbeom Park, Maxim V. Shapovalov, P. Douglas Renfrew, Vikram Khipple Mulligan, Kalli Kappel, Jason W. Labonte, Michael S. Pacella, Richard Bonneau, Philip Bradley, Roland L. Dunbrack, Rhiju Das, David Baker, Brian Kuhlman, Tanja Kortemme, Jeffrey J. Gray - Journal of Chemical Theory and Computation 2017 被引用: 1,570
- Macromolecular modeling and design in Rosetta: recent methods and frameworks
著者: Julia Koehler Leman, Brian D. Weitzner, Steven M. Lewis, Jared Adolf‐Bryfogle, Nawsad Alam, Rebecca F. Alford, Melanie L. Aprahamian, David Baker, Kyle A. Barlow, Patrick Barth, Benjamin Basanta, Brian J. Bender, Kristin Blacklock, Jaume Bonet, Scott E. Boyken, Phil Bradley, Chris Bystroff, Patrick Conway, Seth Cooper, Bruno E. Correia, Brian Coventry, Rhiju Das, René M. de Jong, Frank DiMaio, Lorna Dsilva, Roland L. Dunbrack, Alexander S. Ford, Brandon Frenz, Darwin Fu, Caleb Geniesse, Lukasz Goldschmidt, Ragul Gowthaman, Jeffrey J. Gray, Dominik Gront, Sharon L. Guffy, Scott Horowitz, Po‐Ssu Huang, Thomas Huber, Timothy M. Jacobs, Jeliazko R. Jeliazkov, David K. Johnson, Kalli Kappel, John Karanicolas, Hamed Khakzad, Karen R. Khar, Sagar D. Khare, Firas Khatib, Alisa Khramushin, Indigo C. King, Robert Kleffner, Brian Koepnick, Tanja Kortemme, Georg Kuenze, Brian Kuhlman, Daisuke Kuroda, Jason W. Labonte, Jason Lai, Gideon Lapidoth, Andrew Leaver‐Fay, Steffen Lindert, Thomas W. Linsky, Nir London, Joseph H. Lubin, Sergey Lyskov, Jack B. Maguire, Lars Malmström, Enrique Marcos, Orly Marcu, Nicholas Marze, Jens Meiler, Rocco Moretti, Vikram Khipple Mulligan, Santrupti Nerli, Christoffer Norn, Shane Ó’Conchúir, Noah Ollikainen, Sergey Ovchinnikov, Michael S. Pacella, Xingjie Pan, Hahnbeom Park, Ryan E. Pavlovicz, Manasi A. Pethe, Brian G. Pierce, Kala Bharath Pilla, Barak Raveh, P. Douglas Renfrew, Shourya S. Roy Burman, Aliza B. Rubenstein, Marion F. Sauer, Andreas Scheck, William R. Schief, Ora Schueler‐Furman, Yuval Sedan, Alexander M. Sevy, Nikolaos G. Sgourakis, Lei Shi, Justin B. Siegel, Daniel‐Adriano Silva, Shannon T. Smith, Yifan Song ほか 8 名 - Nature Methods 2020 被引用: 923
- Advances in protein structure prediction and design
著者: Brian Kuhlman, Philip Bradley - Nature Reviews Molecular Cell Biology 2019 被引用: 822
- Rosetta3
著者: Andrew Leaver‐Fay, Michael D. Tyka, Steven M. Lewis, Oliver F. Lange, James Thompson, Ron Jacak, Kristian W. Kaufman, P. Douglas Renfrew, Colin A. Smith, William Sheffler, Ian Davis, Seth Cooper, Adrien Treuille, Daniel J. Mandell, Florian Richter, Yih‐En Andrew Ban, Sarel J. Fleishman, Jacob E. Corn, David E. Kim, Sergey Lyskov, Monica Berrondo, Stuart Mentzer, Zoran Popović, James J. Havranek, John Karanicolas, Rhiju Das, Jens Meiler, Tanja Kortemme, Jeffrey J. Gray, Brian Kuhlman, David Baker, Philip Bradley - Methods in enzymology on CD-ROM/Methods in enzymology 2010 被引用: 2,008
- Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
著者: Brian Kuhlman, Gautam Dantas, Gregory C. Ireton, Gabriele Varani, Barry Stoddard, David Baker - Science 2003 被引用: 1,724
- Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins
著者: Gurkan Guntas, Ryan A. Hallett, Seth P. Zimmerman, Tishan Williams, Hayretin Yumerefendi, James E. Bear, Brian Kuhlman - National Academy of Sciences, Proceedings of the National Academy of Sciences 2014 被引用: 704
- Protein–Protein Docking with Simultaneous Optimization of Rigid-body Displacement and Side-chain Conformations
著者: Jeffrey J. Gray, Stewart Moughon, Chu Wang, Ora Schueler‐Furman, Brian Kuhlman, Carol A. Rohl, David Baker - Journal of Molecular Biology 2003 被引用: 1,169
- Perturbing the energy landscape for improved packing during computational protein design
著者: Jack B. Maguire, Hugh K. Haddox, Devin Strickland, Samer Halabiya, Brian Coventry, Jermel R. Griffin, S.V.S.R.K. Pulavarti, Matthew C. Cummins, David F. Thieker, Eric Klavins, Thomas Szyperski, Frank DiMaio, David Baker, Brian Kuhlman - Proteins Structure Function and Bioinformatics 2020 被引用: 197
- Labelling and optical erasure of synaptic memory traces in the motor cortex
著者: Akiko Hayashi‐Takagi, Sho Yagishita, Mayumi Nakamura, Fukutoshi Shirai, Yi Wu, Amanda L. Loshbaugh, Brian Kuhlman, Klaus M. Hahn, Haruo Kasai - Nature 2015 被引用: 665
- A genetically encoded photoactivatable Rac controls the motility of living cells
著者: Yi Wu, Daniel Frey, Oana I. Lungu, Angelika Jaehrig, Ilme Schlichting, Brian Kuhlman, Klaus M. Hahn - Nature 2009 被引用: 1,107
- A comparison of successful and failed protein interface designs highlights the challenges of designing buried hydrogen bonds
著者: P. Benjamin Stranges, Brian Kuhlman - Protein Science 2012 被引用: 245
- Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE)
著者: Sergey Lyskov, Fang‐Chieh Chou, Shane Ó Conchúir, Bryan S. Der, Kevin Drew, Daisuke Kuroda, Jianqing Xu, Brian D. Weitzner, P. Douglas Renfrew, Parin Sripakdeevong, Benjamin Borgo, James J. Havranek, Brian Kuhlman, Tanja Kortemme, Richard Bonneau, Jeffrey J. Gray, Rhiju Das - PLoS ONE 2013 被引用: 458
- In silico evolution of autoinhibitory domains for a PD-L1 antagonist using deep learning models
著者: Odessa J. Goudy, Amrita Nallathambi, Tomoaki Kinjo, Nicholas Z. Randolph, Brian Kuhlman - National Academy of Sciences, Proceedings of the National Academy of Sciences 2023 被引用: 43
- Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling
著者: Elisa Landoni, Giovanni Fucà, Jian Wang, Venkat R. Chirasani, Zhiyuan Yao, Elena Dukhovlinova, Soldano Ferrone, Barbara Savoldo, Lee K. Hong, Peishun Shou, Silvia Musio, Francesco Padelli, Gaetano Finocchiaro, Miriam Droste, Brian Kuhlman, Abdijapar Shamshiev, Serena Pellegatta, Nikolay V. Dokholyan, Gianpietro Dotti - Cancer Immunology Research 2021 被引用: 77
- Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface
著者: Steven M. Lewis, Xiufeng Wu, Anna Pustilnik, Arlene Sereno, Flora Huang, Heather L Rick, Gurkan Guntas, Andrew Leaver‐Fay, Eric M. Smith, Carolyn Y. Ho, Christophe Hansen‐Estruch, Aaron K. Chamberlain, Stephanie M.E. Truhlar, Elaine M. Conner, S. Atwell, Brian Kuhlman, Stephen J. Demarest - Nature Biotechnology 2014 被引用: 241
- Evolution of a highly active and enantiospecific metalloenzyme from short peptides
著者: Sabine Studer, Douglas A. Hansen, Zbigniew Pianowski, Peer R. E. Mittl, Aaron Debon, Sharon L. Guffy, Bryan S. Der, Brian Kuhlman, Donald Hilvert - Science 2018 被引用: 180
- Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon
著者: Thang Van Nguyen, J. Eugene Lee, Michael J. Sweredoski, Seung-Joo Yang, Seung-Je Jeon, Joseph S. Harrison, Jung-Hyuk Yim, Sang Ghil Lee, Hiroshi Handa, Brian Kuhlman, Ji-Seon Jeong, Justin M. Reitsma, Chul‐Seung Park, Sonja Hess, Raymond J. Deshaies - Molecular Cell 2016 被引用: 179
- LOVTRAP: an optogenetic system for photoinduced protein dissociation
著者: Hui Wang, Marco Vilela, Andreas Winkler, Mirosław Tarnawski, Ilme Schlichting, Hayretin Yumerefendi, Brian Kuhlman, Rihe Liu, Gaudenz Danuser, Klaus M. Hahn - Nature Methods 2016 被引用: 329
- Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3
著者: Hari Kamadurai, Yu Qiu, Alan Deng, Joseph S. Harrison, Chris MacDonald, Marcelo Actis, Patrick Fernandes Rodrigues, Darcie J. Miller, Judith Souphron, Steven M. Lewis, Igor Kurinov, Naoaki Fujii, Michal Hammel, Robert C. Piper, Brian Kuhlman, Brenda A. Schulman - eLife 2013 被引用: 171
- Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides
著者: Tyler L. Grove, Paul M. Himes, Sungwon Hwang, Hayretin Yumerefendi, J.B. Bonanno, Brian Kuhlman, Steven C. Almo, Albert A. Bowers - Journal of the American Chemical Society 2017 被引用: 159
- Native protein sequences are close to optimal for their structures
著者: Brian Kuhlman, David Baker - National Academy of Sciences, Proceedings of the National Academy of Sciences 2000 被引用: 831
- Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C
著者: Nicholas G. Brown, Ryan T. VanderLinden, Edmond R. Watson, Florian Weissmann, Alban Ordureau, Kuen‐Phon Wu, Wei Zhang, Shanshan Yu, Peter Y. Mercredi, Joseph S. Harrison, Iain F. Davidson, Renping Qiao, Ying Lu, Prakash Dube, Michael R. Brunner, Christy R. Grace, Darcie J. Miller, David Haselbach, Marc A. Jarvis, Masaya Yamaguchi, David Yanishevski, Georg Petzold, Sachdev S. Sidhu, Brian Kuhlman, Marc W. Kirschner, J. Wade Harper, Jan‐Michael Peters, Holger Stark, Brenda A. Schulman - Cell 2016 被引用: 162
- Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1
著者: Joseph S. Harrison, Evan M. Cornett, Dennis Goldfarb, Paul A. DaRosa, Zimeng M. Li, Feng Yan, Bradley M. Dickson, Angela H. Guo, Daniel V Cantu, Lilia Kaustov, Peter J. Brown, C.H. Arrowsmith, Dorothy A. Erie, Michael B. Major, Rachel E. Klevit, Krzysztof Krajewski, Brian Kuhlman, Brian D. Strahl, Scott B. Rothbart - eLife 2016 被引用: 147
- Incorporation of Noncanonical Amino Acids into Rosetta and Use in Computational Protein-Peptide Interface Design
著者: P. Douglas Renfrew, Eun Jung Choi, Richard Bonneau, Brian Kuhlman - PLoS ONE 2012 被引用: 128
