Matthew P. Jacobson
1997–2025 年に発表
- 109
- 論文数
- 20,861
- 被引用数
- 68
- h 指数
- 107
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology45.8%
- Medicine24.5%
- Computer Science11.8%
- Chemistry4%
- Materials Science3.1%
- Engineering2.5%
- その他8.3%
トピック
- Computational Drug Discovery Methods6.9%
- Protein Structure and Dynamics5.5%
- Chemical Synthesis and Analysis2.4%
- Enzyme Structure and Function2.3%
- Sirtuins and Resveratrol in Medicine1.8%
- RNA and protein synthesis mechanisms1.7%
- その他79.4%
共著者
- Chakrapani Kalyanaraman22
- Steven C. Almo11
- Diane L. Barber10
- Patricia C. Babbitt9
- R. Scott Lokey8
- Richard A. Friesner8
- Diego Garrido Ruiz7
- Siegfried S. F. Leung7
- Wilian A. Cortopassi7
- Brian K. Shoichet6
- J.A. Gerlt6
- Suwen Zhao6
- Theodore R. Holman6
- Aimee W. Kao5
- Andrej Šali5
- Chaya S. Rapp5
- Niu Huang5
- Alan M. Mathiowetz4
- Amit S. Kalgutkar4
- C. Dale Poulter4
- Christopher L. McClendon4
- David A. Price4
- Gabriela Barreiro4
- Katrina W. Lexa4
全論文
- A hierarchical approach to all‐atom protein loop prediction
著者: Matthew P. Jacobson, David L. Pincus, Chaya S. Rapp, Tyler Day, Barry Honig, David E. Shaw, Richard A. Friesner - Proteins Structure Function and Bioinformatics 2004 被引用: 2,534
- Dysregulated pH: a perfect storm for cancer progression
著者: Bradley A. Webb, Michael S. Chimenti, Matthew P. Jacobson, Diane L. Barber - Nature reviews. Cancer 2011 被引用: 2,229
- Gasdermin D pore structure reveals preferential release of mature interleukin-1
著者: Shiyu Xia, Zhibin Zhang, Venkat Giri Magupalli, Juan Lorenzo Pablo, Ying Dong, Setu M. Vora, Longfei Wang, Tian‐Min Fu, Matthew P. Jacobson, Anna Greka, Judy Lieberman, Jianbin Ruan, Hao Wu - Nature 2021 被引用: 640
- Novel Procedure for Modeling Ligand/Receptor Induced Fit Effects
著者: Woody Sherman, Tyler Day, Matthew P. Jacobson, Richard A. Friesner, Ramy Farid - Journal of Medicinal Chemistry 2005 被引用: 2,030
- SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks
著者: Matthew J. Rardin, Wenjuan He, Yuya Nishida, John C. Newman, Chris Carrico, Steven R. Danielson, Ailan Guo, Philipp Gut, Alexandria K. Sahu, Biao Li, Radha Uppala, Mark Fitch, Timothy Riiff, Lei Zhu, Jing Zhou, Daniel Mulhern, Robert Stevens, Olga Ilkayeva, Christopher B. Newgard, Matthew P. Jacobson, Marc K. Hellerstein, Eric S. Goetzman, Bradford W. Gibson, Eric Verdin - Cell Metabolism 2013 被引用: 721
- On the Role of the Crystal Environment in Determining Protein Side-chain Conformations
著者: Matthew P. Jacobson, Richard A. Friesner, Zhexin Xiang, Barry Honig - Journal of Molecular Biology 2002 被引用: 1,302
- Structure-based discovery of nonopioid analgesics acting through the α 2A -adrenergic receptor
著者: Elissa A. Fink, Jun Xu, Harald Hübner, João M. Bráz, Philipp Seemann, Charlotte Avet, Veronica Craik, Dorothée Weikert, Maximilian F. Schmidt, Chase M. Webb, Nataliya A. Tolmachova, Yurii S. Moroz, Xi‐Ping Huang, Chakrapani Kalyanaraman, Stefan Gahbauer, Geng Chen, Zheng Liu, Matthew P. Jacobson, John J. Irwin, Michel Bouvier, Yang Du, Brian K. Shoichet, Allan I. Basbaum, Peter Gmeiner - Science 2022 被引用: 152
- Cysteine Oxidation in Proteins: Structure, Biophysics, and Simulation
著者: Diego Garrido Ruiz, Angélica Sandoval‐Pérez, Amith Vikram Rangarajan, Emma L. Gunderson, Matthew P. Jacobson - Biochemistry 2022 被引用: 157
- Conformational Flexibility, Internal Hydrogen Bonding, and Passive Membrane Permeability: Successful in Silico Prediction of the Relative Permeabilities of Cyclic Peptides
著者: Taha Rezai, Jonathan Bock, Mai V. Zhou, Chakrapani Kalyanaraman, R. Scott Lokey, Matthew P. Jacobson - Journal of the American Chemical Society 2006 被引用: 418
- SIRT3 Deacetylates Mitochondrial 3-Hydroxy-3-Methylglutaryl CoA Synthase 2 and Regulates Ketone Body Production
著者: Tadahiro Shimazu, Matthew D. Hirschey, Lan Hua, Kristin E. Dittenhafer‐Reed, Bjoern Schwer, David B. Lombard, Li Yu, Jakob Bunkenborg, Frederick W. Alt, John M. Denu, Matthew P. Jacobson, Eric Verdin - Cell Metabolism 2010 被引用: 480
- Testing the Conformational Hypothesis of Passive Membrane Permeability Using Synthetic Cyclic Peptide Diastereomers
著者: Taha Rezai, Bin Yu, Glenn L. Millhauser, Matthew P. Jacobson, R. Scott Lokey - Journal of the American Chemical Society 2006 被引用: 489
- Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis
著者: Shyam Krishnan, Rand M. Miller, Boxue Tian, R. Dyche Mullins, Matthew P. Jacobson, Jack Taunton - Journal of the American Chemical Society 2014 被引用: 266
- Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin
著者: Brian Metcalf, Chih-Yuan Chuang, Kobina Dufu, Mira Patel, Abel Silva‐Garcia, Carl L. Johnson, Qing Lü, James R. Partridge, L.N. Patskovska, Y. Patskovsky, Steven C. Almo, Matthew P. Jacobson, Lan Hua, Qing Xu, Stephen L. Gwaltney, Calvin Yee, Jason Harris, B. Paul Morgan, Joyce James, Donghong Xu, Athiwat Hutchaleelaha, Kumar Paulvannan, Donna Oksenberg, Zhe Li - ACS Medicinal Chemistry Letters 2017 被引用: 190
- On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds
著者: Tina R. White, Chad M. Renzelman, Arthur C Rand, Taha Rezai, Cayla M. McEwen, Vladimir Gelev, Rushia Turner, Roger G. Linington, Siegfried S. F. Leung, Amit S. Kalgutkar, Jonathan Bauman, Yizhong Zhang, Spiros Liras, David A. Price, Alan M. Mathiowetz, Matthew P. Jacobson, R. Scott Lokey - Nature Chemical Biology 2011 被引用: 384
- Beyond Cyclosporine A: Conformation-Dependent Passive Membrane Permeabilities of Cyclic Peptide Natural Products
著者: Christopher Ahlbach, Katrina W. Lexa, Andrew T. Bockus, Valerie Chen, Phillip Crews, Matthew P. Jacobson, R. Scott Lokey - Future Medicinal Chemistry 2015 被引用: 176
- Searching for molecular hypoxia sensors among oxygen-dependent enzymes
著者: Li Li, Susan Q. Shen, Philip E. Bickler, Matthew P. Jacobson, Lani F. Wu, Steven J. Altschuler - eLife 2023 被引用: 43
- Physics-Based Scoring of Protein-Ligand Complexes: Enrichment of Known Inhibitors in Large-Scale Virtual Screening
著者: Niu Huang, Chakrapani Kalyanaraman, John J. Irwin, Matthew P. Jacobson - Journal of Chemical Information and Modeling, J. Chem. Inf. Model. 2005 被引用: 168
- Synthetic group A streptogramin antibiotics that overcome Vat resistance
著者: Qi Li, J. Pellegrino, D. John Lee, Arthur A. Tran, H.A. Chaires, Ruoxi Wang, Jesslyn E. Park, Kaijie Ji, David Chow, Na Zhang, Axel F. Brilot, J.T. Biel, Gydo van Zundert, Kenneth Borrelli, Dean Shinabarger, Cindy L. Wolfe, Beverly Murray, Matthew P. Jacobson, Estelle Mühle, O. Chesneau, James S. Fraser, Ian B. Seiple - Nature 2020 被引用: 118
- Considering Protonation as a Posttranslational Modification Regulating Protein Structure and Function
著者: André Schönichen, Bradley A. Webb, Matthew P. Jacobson, Diane L. Barber - Annual Review of Biophysics 2013 被引用: 175
- Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases
著者: Paul J. Sampognaro, Shruti Arya, Giselle M. Knudsen, Emma L. Gunderson, Angélica Sandoval‐Pérez, Molly Hodul, Kathryn R. Bowles, Charles S. Craik, Matthew P. Jacobson, Aimee W. Kao - Molecular Neurodegeneration 2023 被引用: 37
- A kinematic view of loop closure
著者: Evangelos A. Coutsias, Chaok Seok, Matthew P. Jacobson, Ken A. Dill - Journal of Computational Chemistry, J. Comput. Chem. 2004 被引用: 308
- Molecular mechanics methods for predicting protein–ligand binding
著者: Niu Huang, Chakrapani Kalyanaraman, Katarzyna Bernacki, Matthew P. Jacobson - Physical Chemistry Chemical Physics 2006 被引用: 254
- Experimental Strategies for Functional Annotation and Metabolism Discovery: Targeted Screening of Solute Binding Proteins and Unbiased Panning of Metabolomes
著者: M.W. Vetting, Nawar Al-Obaidi, Suwen Zhao, Brian San Francisco, Jungwook Kim, D. Wichelecki, Jason T. Bouvier, José Solbiati, Hoan Vu, Xinshuai Zhang, Dmitry A. Rodionov, James D. Love, B. Hillerich, R.D. Seidel, Ronald J. Quinn, Andrei L. Osterman, John E. Cronan, Matthew P. Jacobson, J.A. Gerlt, Steven C. Almo - Biochemistry 2014 被引用: 139
- Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration
著者: Swetha Mohan, Paul J. Sampognaro, Andrea R. Argouarch, Jason C. Maynard, Mackenzie Welch, Anand Patwardhan, Emma C. Courtney, Jiasheng Zhang, Amanda R. Mason, Kathy H. Li, Eric J. Huang, William W. Seeley, Bruce L. Miller, Alma L. Burlingame, Matthew P. Jacobson, Aimee W. Kao - Molecular Neurodegeneration 2021 被引用: 53
