Michel Bouvier
1981–2025 年に発表
- 208
- 論文数
- 33,494
- 被引用数
- 109
- h 指数
- 202
- i10 指数
被引用数
引用元
国・地域
機関
分野
- Biochemistry, Genetics and Molecular Biology57%
- Medicine24.5%
- Neuroscience10.1%
- Immunology and Microbiology2.5%
- Psychology1.9%
- Computer Science1%
- その他3%
トピック
- Receptor Mechanisms and Signaling17%
- Neuropeptides and Animal Physiology8.1%
- Neuroscience and Neuropharmacology Research2.7%
- Protein Kinase Regulation and GTPase Signaling2.6%
- Computational Drug Discovery Methods2.2%
- Monoclonal and Polyclonal Antibodies Research1.9%
- その他65.5%
共著者
- Christian Le Gouill20
- Billy Breton14
- Mireille Hogue14
- Stéphane Angers14
- Robert J. Lefkowitz12
- Terence E. Hébert12
- Stéfano Marullo11
- Céline Galès10
- Marc G. Caron10
- Ali Salahpour9
- Charlotte Avet9
- Franziska M. Heydenreich9
- Hiroyuki Kobayashi9
- Madeleine Héroux9
- Stéphane A. Laporte9
- Asuka Inoue8
- Daniel G. Bichet8
- André Laperrière7
- Brian F. O’Dowd7
- Brian K. Kobilka7
- Graeme Milligan7
- Jean-Pierre Morello7
- Martin Audet7
- Shane C. Wright7
全論文
- GPCR activation mechanisms across classes and macro/microscales
著者: Alexander S. Hauser, Albert J. Kooistra, Christian Munk, Franziska M. Heydenreich, Dmitry B. Veprintsev, Michel Bouvier, M. Madan Babu, David E. Gloriam - Nature Structural & Molecular Biology 2021 被引用: 308
- GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling
著者: A. Thomsen, Bianca Plouffe, Thomas J. Cahill, Arun K. Shukla, Jeffrey Tarrasch, Annie Dosey, Alem W. Kahsai, Ryan T. Strachan, Biswaranjan Pani, Jacob P. Mahoney, Li-Yin Huang, Billy Breton, Franziska M. Heydenreich, Roger K. Sunahara, Georgios Skiniotis, Michel Bouvier, Robert J. Lefkowitz - Cell 2016 被引用: 578
- Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET
著者: Yoon Namkung, Christian Le Gouill, Viktoria Lukashova, Hiroyuki Kobayashi, Mireille Hogue, Étienne Khoury, Mideum Song, Michel Bouvier, Stéphane A. Laporte - Nature Communications 2016 被引用: 350
- Community guidelines for GPCR ligand bias: IUPHAR review 32
著者: Peter Kolb, Terry Kenakin, S P H Alexander, Marcel Bermúdez, Laura Bohn, Christian S. Breinholt, Michel Bouvier, Stephen J. Hill, Evi Kostenis, Kirill A. Martemyanov, Rick R. Neubig, H. Ongun Onaran, Sudarshan Rajagopal, Bryan L. Roth, Jana Selent, Arun K. Shukla, M. Sommer, David E. Gloriam - British Journal of Pharmacology 2022 被引用: 222
- Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling
著者: Mette Trauelsen, Thomas K. Hiron, Da Lin, Jacob E. Petersen, Billy Breton, Anna Sofie Husted, Siv A. Hjorth, Asuka Inoue, Thomas M. Frimurer, Michel Bouvier, Christopher A. O’Callaghan, Thue W. Schwartz - Cell Reports 2021 被引用: 169
- Structure-based discovery of nonopioid analgesics acting through the α 2A -adrenergic receptor
著者: Elissa A. Fink, Jun Xu, Harald Hübner, João M. Bráz, Philipp Seemann, Charlotte Avet, Veronica Craik, Dorothée Weikert, Maximilian F. Schmidt, Chase M. Webb, Nataliya A. Tolmachova, Yurii S. Moroz, Xi‐Ping Huang, Chakrapani Kalyanaraman, Stefan Gahbauer, Geng Chen, Zheng Liu, Matthew P. Jacobson, John J. Irwin, Michel Bouvier, Yang Du, Brian K. Shoichet, Allan I. Basbaum, Peter Gmeiner - Science 2022 被引用: 152
- Common coupling map advances GPCR-G protein selectivity
著者: Alexander S Hauser, Charlotte Avet, Claire Normand, Arturo Mancini, Asuka Inoue, Michel Bouvier, David E Gloriam - eLife 2022 被引用: 131
- Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis
著者: Thomas J. Cahill, A. Thomsen, Jeffrey Tarrasch, Bianca Plouffe, Anthony H. Nguyen, Fan Yang, Li-Yin Huang, Alem W. Kahsai, Daniel L. Bassoni, Bryant J. Gavino, Jane E. Lamerdin, Sarah Triest, Arun K. Shukla, Benjamin Berger, John R. Little, Albert Antar, Adi Blanc, Chang-xiu Qu, Xin Chen, Kouki Kawakami, Asuka Inoue, Junken Aoki, Jan Steyaert, Jin‐Peng Sun, Michel Bouvier, Georgios Skiniotis, Robert J. Lefkowitz - National Academy of Sciences, Proceedings of the National Academy of Sciences 2017 被引用: 385
- BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated G q activation at early endosomes
著者: Shane C. Wright, Viktoriya Lukasheva, Christian Le Gouill, Hiroyuki Kobayashi, Billy Breton, Samuel Mailhot-Larouche, Élodie Blondel-Tepaz, Nichelle Antunes Vieira, Cláudio M. Costa-Neto, Madeleine Héroux, Nevin A. Lambert, Lucas T. Parreiras‐e‐Silva, Michel Bouvier - National Academy of Sciences, Proceedings of the National Academy of Sciences 2021 被引用: 66
- Probing the activation-promoted structural rearrangements in preassembled receptor–G protein complexes
著者: Céline Galès, Joost J J Van Durm, Stéphane Schaak, Stéphanie M. Pontier, Yann Percherancier, Martin Audet, Hervé Paris, Michel Bouvier - Nature Structural & Molecular Biology 2006 被引用: 454
- The experimental power of FR900359 to study Gq-regulated biological processes
著者: Ramona Schrage, Anna-Lena Schmitz, Evelyn Gaffal, Suvi Annala, Stefan Kehraus, Daniela Wenzel, Katrin M. Büllesbach, Tobias Bald, Asuka Inoue, Yuji Shinjo, Ségolène Galandrin, Naveen Shridhar, Michael Hesse, Manuel Grundmann, Nicole Merten, Thomas H. Charpentier, Matthew Martz, Adrian J. Butcher, Tanja Slodczyk, Sylvain Armando, Maike Effern, Yoon Namkung, Laura Jenkins, Velten Horn, Anne Stößel, Harald Dargatz, Daniel Tietze, Diana Imhof, Céline Galès, Christel Drewke, Christa E. Müller, Michael Hölzel, Graeme Milligan, Andrew B. Tobin, Jesús Gomeza, Henrik Dohlman, John Sondek, T. Kendall Harden, Michel Bouvier, Stéphane A. Laporte, Junken Aoki, Bernd K. Fleischmann, Klaus Mohr, Gabriele M. König, Thomas Tüting, Evi Kostenis - Nature Communications 2015 被引用: 372
- The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites
著者: Janik B. Hedderich, Margherita Persechino, Katharina Becker, Franziska M. Heydenreich, Torben Gutermuth, Michel Bouvier, Moritz Bünemann, Peter Kolb - Nature Communications 2022 被引用: 116
- How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling
著者: Naomi R. Latorraca, Matthieu Masureel, Scott A. Hollingsworth, Franziska M. Heydenreich, Carl‐Mikael Suomivuori, Connor Brinton, Raphael J.L. Townshend, Michel Bouvier, Brian K. Kobilka, Ron O. Dror - Cell 2020 被引用: 184
- Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region
著者: A. J. Venkatakrishnan, Xavier Deupí, Guillaume Lebon, Franziska M. Heydenreich, Tilman Flock, Tamara Miljus, Santhanam Balaji, Michel Bouvier, Dmitry B. Veprintsev, Christopher G. Tate, Gebhard F. X. Schertler, M. Madan Babu - Nature, Nat. 2016 被引用: 311
- Bioluminescence resonance energy transfer–based imaging of protein–protein interactions in living cells
著者: Hiroyuki Kobayashi, Louis-Philippe Picard, Anne-Marie Schönegge, Michel Bouvier - Nature Protocols 2019 被引用: 121
- GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics
著者: Shane C. Wright, Aikaterini Motso, Stefania Koutsilieri, Christian M. Beusch, Pierre Sabatier, Alessandro Berghella, Élodie Blondel-Tepaz, Kimberley Mangenot, Ioannis Pittarokoilis, Despoina-Christina Sismanoglou, Christian Le Gouill, Jesper V. Olsen, Roman A. Zubarev, Nevin A. Lambert, Alexander S. Hauser, Michel Bouvier, Volker M. Lauschke - Nature Communications 2023 被引用: 46
- Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation
著者: Bas Brouwers, Edson Mendes de Oliveira, Maria Martí-Solano, Fabíola Branco Filippin-Monteiro, Suli‐Anne Laurin, Julia M. Keogh, Elana Henning, Rebecca Bounds, Carole Daly, Shane Houston, V. Ayinampudi, Natalia Wasiluk, David T. Clarke, Bianca Plouffe, Michel Bouvier, M. Madan Babu, I. Sadaf Farooqi, Jacek Mokrosiński - Cell Reports 2021 被引用: 87
- Real-time monitoring of receptor and G-protein interactions in living cells
著者: Céline Galès, R. Victor Rebois, Mireille Hogue, Phan Trieu, Andreas Breit, Terence E. Hébert, Michel Bouvier - Nature Methods 2005 被引用: 417
- Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors
著者: Yoon Namkung, Christian LeGouill, Sahil Kumar, Yubo Cao, Larissa B. Teixeira, Viktoriya Lukasheva, Jenna Giubilaro, Sarah C. Simões, Jean‐Michel Longpré, Dominic Devost, Terence E. Hébert, Graciela Piñeyro, Richard Leduc, Cláudio M. Costa-Neto, Michel Bouvier, Stéphane A. Laporte - Science Signaling 2018 被引用: 156
- Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9
著者: Louis M. Luttrell, Jialu Wang, Bianca Plouffe, Jeffrey S. Smith, Lama Yamani, Suneet Kaur, Pierre‐Yves Jean‐Charles, Christophe Gauthier, Mi‐Hye Lee, Biswaranjan Pani, Ji‐Hee Kim, Seungkirl Ahn, Sudarshan Rajagopal, Éric Reiter, Michel Bouvier, Sudha K. Shenoy, Stéphane A. Laporte, Howard A. Rockman, Robert J. Lefkowitz - Science Signaling 2018 被引用: 213
- Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist
著者: Matthieu Masureel, Yaozhong Zou, Louis-Philippe Picard, Emma T. van der Westhuizen, Jacob P. Mahoney, João Rodrigues, Thomas J. Mildorf, Ron O. Dror, David E. Shaw, Michel Bouvier, Els Pardon, Jan Steyaert, Roger K. Sunahara, William I. Weis, Cheng Zhang, Brian K. Kobilka - Nature Chemical Biology 2018 被引用: 203
- Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein
著者: Julie Quoyer, Jay M. Janz, Jiansong Luo, Yong Ren, Sylvain Armando, Viktoria Lukashova, Jeffrey Benovic, Kenneth E. Carlson, S. Hunt, Michel Bouvier - National Academy of Sciences, Proceedings of the National Academy of Sciences 2013 被引用: 181
- Quantification of Ligand Bias for Clinically Relevant β2-Adrenergic Receptor Ligands: Implications for Drug Taxonomy
著者: Emma T. van der Westhuizen, Billy Breton, Arthur Christopoulos, Michel Bouvier - Molecular Pharmacology 2013 被引用: 233
- A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling
著者: Alexandre Beautrait, Justine S. Paradis, Brandon Zimmerman, Jenna Giubilaro, Ljiljana Nikolajev, Sylvain Armando, Hiroyuki Kobayashi, Lama Yamani, Yoon Namkung, Franziska M. Heydenreich, Étienne Khoury, Martin Audet, Philippe P. Roux, Dmitry B. Veprintsev, Stéphane A. Laporte, Michel Bouvier - Nature Communications 2017 被引用: 219
