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Timothy M. Willson

1988–2025 年に発表

別表記
Timothy M Willson
171
論文数
65,316
被引用数
110
h 指数
163
i10 指数

被引用数

Timothy M. Willson の年別被引用数1987 年: 被引用 2 件1988 年: 被引用 1 件1989 年: 被引用 2 件1994 年: 被引用 4 件1995 年: 被引用 14 件1996 年: 被引用 69 件1997 年: 被引用 148 件1998 年: 被引用 292 件1999 年: 被引用 475 件2000 年: 被引用 780 件2001 年: 被引用 894 件2002 年: 被引用 1,314 件2003 年: 被引用 1,398 件2004 年: 被引用 1,246 件2005 年: 被引用 1,173 件2006 年: 被引用 1,218 件2007 年: 被引用 1,040 件2008 年: 被引用 999 件2009 年: 被引用 808 件2010 年: 被引用 852 件2011 年: 被引用 638 件2012 年: 被引用 676 件2013 年: 被引用 640 件2014 年: 被引用 541 件2015 年: 被引用 451 件2016 年: 被引用 433 件2017 年: 被引用 532 件2018 年: 被引用 504 件2019 年: 被引用 1,361 件2020 年: 被引用 1,366 件2021 年: 被引用 1,292 件2022 年: 被引用 959 件2023 年: 被引用 741 件2024 年: 被引用 961 件2025 年: 被引用 533 件2026 年: 被引用 20 件1990〜1993 年は被引用が無いため表示していません

引用元

国・地域

この著者を引用した国・地域の世界地図アメリカ合衆国: 引用元論文 6,884 件、この内訳の 33.6%中国: 引用元論文 1,751 件、この内訳の 8.6%イギリス: 引用元論文 1,321 件、この内訳の 6.5%ドイツ: 引用元論文 1,047 件、この内訳の 5.1%フランス: 引用元論文 943 件、この内訳の 4.6%日本: 引用元論文 893 件、この内訳の 4.4%イタリア: 引用元論文 684 件、この内訳の 3.3%カナダ: 引用元論文 665 件、この内訳の 3.2%オランダ: 引用元論文 487 件、この内訳の 2.4%スウェーデン: 引用元論文 481 件、この内訳の 2.3%スイス: 引用元論文 472 件、この内訳の 2.3%オーストラリア: 引用元論文 438 件、この内訳の 2.1%
0%33.6%その他 21.6%

機関

分野

  • Medicine39.7%
  • Biochemistry, Genetics and Molecular Biology38.7%
  • Pharmacology, Toxicology and Pharmaceutics4.4%
  • Neuroscience4.2%
  • Computer Science3.5%
  • Immunology and Microbiology3.3%
  • その他6.2%

トピック

  • Peroxisome Proliferator-Activated Receptors8.3%
  • Drug Transport and Resistance Mechanisms5.6%
  • Cholesterol and Lipid Metabolism3.5%
  • Estrogen and related hormone effects3.5%
  • Adipose Tissue and Metabolism3.4%
  • Liver Disease Diagnosis and Treatment2.6%
  • その他73.1%

共著者

全論文

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  1. A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

    著者: Bryan Goodwin, Stacey A. Jones, Roger R. Price, Michael A. Watson, David D. McKee, Linda B. Moore, Cristin M. Galardi, Joan G. Wilson, Michael C. Lewis, Matthew E. Roth, Patrick Maloney, Timothy M. Willson, Steven A. Kliewer - Molecular Cell 2000 被引用: 1,905

  2. Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

    著者: Derek J. Parks, Steven G. Blanchard, Randy K. Bledsoe, Gyan Chandra, Thomas G. Consler, Steven A. Kliewer, Julie B. Stimmel, Timothy M. Willson, Ann Marie Zavacki, David D. Moore, Jürgen M. Lehmann - Science 1999 被引用: 2,262

  3. Tapinarof Is a Natural AhR Agonist that Resolves Skin Inflammation in Mice and Humans

    著者: Susan Smith, Channa Jayawickreme, David J. Rickard, Edwige Nicodème, Thi Tho Bui, Cathy Simmons, Christine M. Coquery, Jessica Neil, William M. Pryor, David Mayhew, Deepak K. Rajpal, Katrina L. Creech, Sylvia M. Furst, James Lee, Dalei Wu, Fraydoon Rastinejad, Timothy M. Willson, Fabrice Viviani, David C. Morris, John T. Moore, Javier Cote-Sierra - Journal of Investigative Dermatology 2017 被引用: 370

  4. Generative and reinforcement learning approaches for the automated de novo design of bioactive compounds

    著者: Maria Korshunova, Niles Huang, Stephen J. Capuzzi, Dmytro S. Radchenko, Olena Savych, Yuriy S. Moroz, Carrow I. Wells, Timothy M. Willson, Alexander Tropsha, Olexandr Isayev - Communications Chemistry 2022 被引用: 104

  5. The promise and peril of chemical probes

    著者: C.H. Arrowsmith, James E. Audia, Christopher P. Austin, Jonathan B. Baell, Jonathan P. Bennett, Julian Blagg, C. Bountra, Paul E. Brennan, Peter J. Brown, Mark E. Bunnage, Carolyn Buser‐Doepner, Robert M Campbell, Adrian J. Carter, Philip Cohen, Robert A. Copeland, Ben Cravatt, Jayme L. Dahlin, Dashyant Dhanak, A.M. Edwards, Mathias Frederiksen, Stephen V. Frye, Nathanael S. Gray, Charles E. Grimshaw, David Hepworth, Trevor Howe, K. Huber, Jian Jin, Stefan Knapp, Joanne Kotz, Ryan G. Kruger, Derek Lowe, Mary M. Mader, Brian D. Marsden, Anke Mueller‐Fahrnow, Susanne Müller, Rónán C. O’Hagan, John P. Overington, Dafydd R. Owen, Saul H. Rosenberg, Ruth A. Ross, Bryan L. Roth, Matthieu Schapira, Stuart L. Schreiber, Brian K. Shoichet, M. Sundström, Giulio Superti-Furga, Jack Taunton, Leticia Toledo‐Sherman, Chris Walpole, Michael A. Walters, Timothy M. Willson, Paul Workman, Robert N. Young, William J. Zuercher - Nature Chemical Biology 2015 被引用: 850

  6. CACHE (Critical Assessment of Computational Hit-finding Experiments): A public–private partnership benchmarking initiative to enable the development of computational methods for hit-finding

    著者: Suzanne Ackloo, Rima Al‐awar, Rommie E. Amaro, C.H. Arrowsmith, Hatylas Azevedo, Robert A. Batey, Yoshua Bengio, Ulrich A. K. Betz, Cristian Bologa, John D. Chodera, Wendy D. Cornell, Ian Dunham, Gerhard F. Ecker, Kristina Edfeldt, A.M. Edwards, Michael K. Gilson, Cláudia R. Gordijo, Gerhard Heßler, Alexander Hillisch, Anders Hogner, John J. Irwin, Johanna M. Jansen, Daniel Kühn, Andrew R. Leach, Alpha A. Lee, Uta Lessel, Maxwell R. Morgan, John Moult, Ingo Muegge, Tudor I. Oprea, Benjamin Perry, Patrick Riley, Sophie A. L. Rousseaux, Kumar Singh Saikatendu, Vijayaratnam Santhakumar, Matthieu Schapira, Cora Scholten, Matthew H. Todd, Masoud Vedadi, Andrea Volkamer, Timothy M. Willson - Nature Reviews Chemistry 2022 被引用: 102

  7. ApoE Promotes the Proteolytic Degradation of Aβ

    著者: Qingguang Jiang, C.Y. Daniel Lee, Shweta Mandrekar, Brandy Wilkinson, Paige E. Cramer, Noam Zelcer, Karen M. Mann, Bruce T. Lamb, Timothy M. Willson, Jon L. Collins, Jill Richardson, Jonathan D. Smith, Thomas A. Comery, David Riddell, David M. Holtzman, Peter Tontonoz, Gary E. Landreth - Neuron 2008 被引用: 867

  8. Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

    著者: Yanqiao Zhang, Florence Ying Lee, Gabriel Barrera, Hans C. Lee, Charisse Vales, Frank J. Gonzalez, Timothy M. Willson, Peter A. Edwards - National Academy of Sciences, Proceedings of the National Academy of Sciences 2006 被引用: 937

  9. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

    著者: Steven A. Kliewer, Scott S. Sundseth, Stacey A. Jones, Peter J. Brown, G. Bruce Wisely, Cecilia S. Koble, Pallavi R. Devchand, Walter Wahli, Timothy M. Willson, James M. Lenhard, Jürgen M. Lehmann - National Academy of Sciences, Proceedings of the National Academy of Sciences 1997 被引用: 2,153

  10. 6α-Ethyl-Chenodeoxycholic Acid (6-ECDCA), a Potent and Selective FXR Agonist Endowed with Anticholestatic Activity

    著者: Roberto Pellicciari, Stefano Fiorucci, Emidio Camaioni, Carlo Clerici, Gabriele Costantino, Patrick Maloney, Antonio Morelli, Derek J. Parks, Timothy M. Willson - Journal of Medicinal Chemistry 2002 被引用: 731

  11. An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

    著者: Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver, William O. Wilkison, Timothy M. Willson, Steven A. Kliewer - Journal of Biological Chemistry 1995 被引用: 3,629

  12. The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

    著者: Mercedes Ricote, Andrew C. Li, Timothy M. Willson, Carolyn Kelly, Christopher K. Glass - Nature 1998 被引用: 3,527

  13. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

    著者: Robert T. Nolte, G. Bruce Wisely, Stefan Westin, Jeffery E. Cobb, Millard H. Lambert, Riki Kurokawa, Michael G. Rosenfeld, Timothy M. Willson, Christopher K. Glass, Michael V. Milburn - Nature 1998 被引用: 1,956

  14. An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

    著者: Steven A. Kliewer, John T. Moore, Laura Wade, Jeff L. Staudinger, Michael A Watson, Stacey A. Jones, David D. McKee, Beverly B. Oliver, Timothy M. Willson, Rolf Zetterström, Thomas Perlmann, Jürgen M. Lehmann - Cell 1998 被引用: 1,549

  15. Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement

    著者: James D. Vasta, Cesear Corona, Jennifer Wilkinson, Chad Zimprich, James R. Hartnett, Morgan R. Ingold, Kristopher Zimmerman, Thomas Machleidt, Thomas A. Kirkland, Kristin G. Huwiler, Rachel Friedman Ohana, Michael R. Slater, Paul Otto, Mei Cong, Carrow I. Wells, Benedict‐Tilman Berger, Thomas Hanke, Carina Glas, Ke Ding, David H. Drewry, K. Huber, Timothy M. Willson, Stefan Knapp, Susanne Müller, Poncho Meisenheimer, Frank Fan, Keith V. Wood, Matthew B. Robers - Cell chemical biology 2017 被引用: 293

  16. The PPARs: From Orphan Receptors to Drug Discovery

    著者: Timothy M. Willson, Peter J. Brown, Daniel D. Sternbach, Brad R. Henke - Journal of Medicinal Chemistry 2000 被引用: 1,804

  17. A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ

    著者: Gabriel Pascual, Amy L. Fong, Sumito Ogawa, Amir Gamliel, Andrew C. Li, Valentina Perissi, David W. Rose, Timothy M. Willson, Michael G. Rosenfeld, Christopher K. Glass - Nature 2005 被引用: 1,234

  18. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

    著者: J�rgen Lehmann, David D. McKee, M. A. Watson, Timothy M. Willson, John T. Moore, Steven A. Kliewer - Journal of Clinical Investigation 1998 被引用: 1,571

  19. The Nuclear Pregnane X Receptor: A Key Regulator of Xenobiotic Metabolism

    著者: Steven A. Kliewer, Bryan Goodwin, Timothy M. Willson - Endocrine Reviews 2002 被引用: 919

  20. Pxr, car and drug metabolism

    著者: Timothy M. Willson, Steven A. Kliewer - Nature Reviews Drug Discovery 2002 被引用: 497

  21. Synthetic LXR ligand inhibits the development of atherosclerosis in mice

    著者: Sean B. Joseph, Elaine McKilligin, Liming Pei, Michael A. Watson, Alan R. Collins, Bryan Laffitte, Mingyi Chen, Grace Noh, Joanne Goodman, Graham N. Hagger, Jonathan Tran, Tim K. Tippin, Xuping Wang, Aldons J. Lusis, Willa A. Hsueh, Ronald E. Law, Jon L. Collins, Timothy M. Willson, Peter Tontonoz - National Academy of Sciences, Proceedings of the National Academy of Sciences 2002 被引用: 939

  22. Crowdsourced mapping of unexplored target space of kinase inhibitors

    著者: Anna Cichońska, Balaguru Ravikumar, Robert J. Allaway, Fang Wan, Sung‐Joon Park, Olexandr Isayev, Shuya Li, Mike J. Mason, Andrew Lamb, Ziaurrehman Tanoli, Minji Jeon, Sunkyu Kim, Mariya Popova, Stephen J. Capuzzi, Jianyang Zeng, Kristen K. Dang, Gregory Koytiger, Jaewoo Kang, Carrow I. Wells, Timothy M. Willson, User oselot, Mehmet Tan, Team N121, Chih-Han Huang, Edward S.C. Shih, Tsai‐Min Chen, Chih‐Hsun Wu, Wei-Quan Fang, Jhih-Yu Chen, Ming‐Jing Hwang, Team Let_Data_Talk, Xiaokang Wang, Marouen Ben Guebila, Behrouz Shamsaei, Sourav Singh, User thinng, Thin Nguyen, Team KKT, Mostafa Karimi, Di Wu, Zhangyang Wang, Yang Shen, Team Boun, Hakime Öztürk, Elif Özkırımlı, Arzucan Özgür, Team KinaseHunter, Hansaim Lim, Lei Xie, Team AmsterdamUMC-KU-team, Georgi K. Kanev, Albert J. Kooistra, Bart A. Westerman, Team DruginaseLearning, P.J. Terzopoulos, Konstantinos Ntagiantas, Christos Fotis, Leonidas G. Alexopoulos, Dimitri Boeckaerts, Michiel Stock, Bernard De Baets, Yves Briers, Team QED, Yunan Luo, Hailin Hu, Jian Peng, Team METU_EMBLEBI_CROssBAR, Tunca Doğan, Ahmet Süreyya Rifaioğlu, Heval Ataş, Rengül Çetin-Atalay, Volkan Atalay, María Martin, Team DMIS_DK, Minji Jeon, Junhyun Lee, Seongjun Yun, Bumsoo Kim, Buru Chang, Team AI Winter is Coming, Team hulab, Gábor Turu, Ádám Misák, Bence Szalai, László Hunyady, Team ML-Med, Matthias Lienhard, Paul Prasse, Ivo Bachmann, Julia Ganzlin, Gal Barel, Ralf Herwig, Team Prospectors, Davor Oršolić, Bono Lučić, Višnja Stepanić, Tomislav Šmuc, Challenge organizers, Tudor I. Oprea, Avner Schlessinger ほか 5 名 - Nature Communications 2021 被引用: 88

  23. Activation of the Nuclear Receptor LXR by Oxysterols Defines a New Hormone Response Pathway

    著者: Jürgen M. Lehmann, Steven A. Kliewer, Linda B. Moore, Tracey Smith-Oliver, Beverly B. Oliver, Jui Lan Su, Scott S. Sundseth, Deborah A. Winegar, Daniel E. Blanchard, Thomas A. Spencer, Timothy M. Willson - Journal of Biological Chemistry 1997 被引用: 1,232

  24. Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation

    著者: Marie Pariollaud, Julie Gibbs, Thomas Hopwood, Sheila Brown, Nicola Begley, Ryan Vonslow, Toryn Poolman, Baoqiang Guo, Ben Saer, D. Heulyn Jones, James P. Tellam, Stefano Bresciani, Nicholas C. O. Tomkinson, Justyna Wojno-Picon, Anthony W.J. Cooper, Dion A. Daniels, Ryan P. Trump, Daniel Grant, William J. Zuercher, Timothy M. Willson, Andrew S. MacDonald, Brian Bolognese, Patricia L. Podolin, Yolanda Sánchez, Andrew Loudon, David Ray - Journal of Clinical Investigation 2018 被引用: 205