Alexander Tarakhovsky
Active 1994–2025
- 59
- Papers
- 18,322
- Citations
- 57
- h-index
- 58
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology52.3%
- Immunology and Microbiology21.8%
- Medicine20.7%
- Neuroscience3.1%
- Agricultural and Biological Sciences0.9%
- Chemistry0.2%
- Other1%
Topics
- Epigenetics and DNA Methylation6.8%
- Immune Cell Function and Interaction5.6%
- T-cell and B-cell Immunology5%
- MicroRNA in disease regulation3.5%
- Protein Degradation and Inhibitors3.2%
- Cancer-related gene regulation2.5%
- Other73.4%
Coauthors
- Ingrid Mecklenbräuker13
- I-hsin Su10
- Klaus Rajewsky10
- Dónal O’Carroll8
- Kaoru Saijo6
- Rab K. Prinjha6
- Uwe Schaefer6
- Christian Schmedt5
- Marc‐Werner Dobenecker5
- Kevin Lee4
- M. Azim Surani4
- Michael Leitges4
- Michel C. Nussenzweig4
- Scott Dewell4
- Alina Patke3
- Anne Schaefer3
- Brian T. Chait3
- Elaine Fuchs3
- Ivan Marazzi3
- Masato Okada3
- Nigel Killeen3
- Sheila C. Barton3
- Srihari C. Sampath3
- Ângela Patrícia Santana3
All papers
- Suppression of inflammation by a synthetic histone mimic
Authors: Edwige Nicodème, Kate L. Jeffrey, Uwe Schaefer, Sören Beinke, Scott Dewell, Chun‐wa Chung, Rohit Chandwani, Ivan Marazzi, Paul A. Wilson, Hervé Coste, Julia H. White, Jorge Kirilovsky, Charles M. Rice, José M. Lora, Rab K. Prinjha, Kevin Lee, Alexander Tarakhovsky - Nature 2010 cited by 1,584
- Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex
Authors: João D. Pereira, Stephen N. Sansom, James Smith, Marc‐Werner Dobenecker, Alexander Tarakhovsky, Frederick J. Livesey - National Academy of Sciences, Proceedings of the National Academy of Sciences 2010 cited by 476
- Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration
Authors: Melanie von Schimmelmann, Philip A. Feinberg, Josefa M. Sullivan, Stacy M. Ku, Ana Badimon, Mary Kaye Duff, Zichen Wang, Alexander Lachmann, Scott Dewell, Avi Ma’ayan, Ming‐Hu Han, Alexander Tarakhovsky, Anne Schaefer - Nature Neuroscience 2016 cited by 240
- Blimp1 is a critical determinant of the germ cell lineage in mice
Authors: Yasuhide Ohinata, Bernhard Payer, Dónal O’Carroll, Katia Ancelin, Yukiko Ono, Mitsue Sano, Sheila C. Barton, Tetyana V. Obukhanych, Michel C. Nussenzweig, Alexander Tarakhovsky, Mitinori Saitou, M. Azim Surani - Nature 2005 cited by 1,054
- Ezh2 Orchestrates Gene Expression for the Stepwise Differentiation of Tissue-Specific Stem Cells
Authors: Elena Ezhkova, H. Amalia Pasolli, Joel S. Parker, Nicole Stokes, I-hsin Su, Gregory J. Hannon, Alexander Tarakhovsky, Elaine Fuchs - Cell 2009 cited by 619
- Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice
Authors: Ariel Halper-Stromberg, Ching-Lan Lu, Florian Klein, Joshua A. Horwitz, Stylianos Bournazos, Lilian Nogueira, Thomas Eisenreich, Cassie Liu, Anna Gazumyan, Uwe Schaefer, Rebecca C. Furze, Michael S. Seaman, Rab K. Prinjha, Alexander Tarakhovsky, Jeffrey V. Ravetch, Michel C. Nussenzweig - Cell 2014 cited by 379
- Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation
Authors: Martina Minnich, Hiromi Tagoh, Peter Bönelt, Elin Axelsson, Maria Fischer, Beatriz Cebolla, Alexander Tarakhovsky, Stephen L. Nutt, Markus Jaritz, Meinrad Busslinger - Nature Immunology 2016 cited by 321
- Maternal microRNAs are essential for mouse zygotic development
Authors: Fuchou Tang, Masahiro Kaneda, Dónal O’Carroll, Petra Hájková, Sheila C. Barton, Yunguang Sun, Caroline Lee, Alexander Tarakhovsky, Kaiqin Lao, M. Azim Surani - Genes & Development 2007 cited by 579
- Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity
Authors: Ian Maze, Herbert E. Covington, David Dietz, Quincey LaPlant, William Renthal, Scott J. Russo, Max Mechanic, Ezekiell Mouzon, Rachael L. Neve, Stephen J. Haggarty, Yanhua Ren, Srihari C. Sampath, Yasmin L. Hurd, Paul Greengard, Alexander Tarakhovsky, Anne Schaefer, Eric J. Nestler - Science 2010 cited by 660
- Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement
Authors: I-hsin Su, Ashwin Basavaraj, Andrew N. Krutchinsky, Oliver Hobert, Axel Ullrich, Brian T. Chait, Alexander Tarakhovsky - Nature Immunology 2002 cited by 596
- Chromatin Contributions to the Regulation of Innate Immunity
Authors: Stephen T. Smale, Alexander Tarakhovsky, Gioacchino Natoli - Annual Review of Immunology 2014 cited by 197
- Polycomb Group Protein Ezh2 Controls Actin Polymerization and Cell Signaling
Authors: I-hsin Su, Marc‐Werner Dobenecker, Ephraim Y. Dickinson, Matthew G. Oser, Ashwin Basavaraj, Raphael Marqueron, Agnès Viale, Danny Reinberg, Christoph Wülfing, Alexander Tarakhovsky - Cell 2005 cited by 368
- BLIMP1 Is a Tumor Suppressor Gene Frequently Disrupted in Activated B Cell-like Diffuse Large B Cell Lymphoma
Authors: Jonathan Mandelbaum, Govind Bhagat, Hongyan Tang, Tongwei Mo, Manisha Brahmachary, Qiong Shen, Amy Chadburn, Klaus Rajewsky, Alexander Tarakhovsky, Laura Pasqualucci, Riccardo Dalla‐Favera - Cancer Cell 2010 cited by 280
- Control of Cognition and Adaptive Behavior by the GLP/G9a Epigenetic Suppressor Complex
Authors: Anne Schaefer, Srihari C. Sampath, Adam Intrator, Alice K. Min, Tracy S. Gertler, D. James Surmeier, Alexander Tarakhovsky, Paul Greengard - Neuron 2009 cited by 316
- A Role for CD5 in TCR-Mediated Signal Transduction and Thymocyte Selection
Authors: Alexander Tarakhovsky, Steven B. Kanner, Joachim Hombach, Jeffrey A. Ledbetter, Werner Müller, Nigel Killeen, Klaus Rajewsky - Science 1995 cited by 451
- Polycomb protein Ezh2 regulates pancreatic β-cell Ink4a/Arf expression and regeneration in diabetes mellitus
Authors: Hainan Chen, Xueying Gu, I-hsin Su, Rita Bottino, Juan L. Contreras, Alexander Tarakhovsky, Seung K. Kim - Genes & Development 2009 cited by 371
- Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development
Authors: Sylvia Erhardt, I-hsin Su, Robert Schneider, Sheila C. Barton, Andrew J. Bannister, Laura Perez-Burgos, Thomas Jenuwein, Tony Kouzarides, Alexander Tarakhovsky, M. Azim Surani - Development 2003 cited by 329
- Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling
Authors: Dan Levy, Alex Kuo, Yanqi Chang, Uwe Schaefer, Christopher Kitson, Peggie Cheung, Alexsandra Espejo, Barry M. Zee, Chih Long Liu, Stephanie Tangsombatvisit, Ruth I. Tennen, Andrew Kuo, Tanjing Song, Regina Cheung, Katrin F. Chua, Paul J. Utz, Xiaobing Shi, Rab K. Prinjha, Kevin Lee, Benjamin A. García, Mark T. Bedford, Alexander Tarakhovsky, Xiaodong Cheng, Or Gozani - Nature Immunology 2010 cited by 255
- PKCβ modulates antigen receptor signaling via regulation of Btk membrane localization
Authors: Shin‐Wook Kang, Matthew I. Wahl, Julia Chu, Jiro Kitaura, Yuko Kawakami, R. Kato, Ruby S. Tabuchi, Alexander Tarakhovsky, Toshiaki Kawakami, Christoph W. Turck, Owen N. Witte, David J. Rawlings - The EMBO Journal 2001 cited by 148
- MicroRNA Biogenesis Is Required for Mouse Primordial Germ Cell Development and Spermatogenesis
Authors: Katsuhiko Hayashi, Susana M. Chuva de Sousa Lopes, Masahiro Kaneda, Fuchou Tang, Petra Hájková, Kaiqin Lao, Dónal O’Carroll, Partha Pratim Das, Alexander Tarakhovsky, Eric A. Miska, M. Azim Surani - PLoS ONE 2008 cited by 498
- Suppression of the antiviral response by an influenza histone mimic
Authors: Ivan Marazzi, Jessica Ho, Jaehoon Kim, Balaji Manicassamy, Scott Dewell, Randy A. Albrecht, Chris W. Seibert, Uwe Schaefer, Kate L. Jeffrey, Rab K. Prinjha, Kevin Lee, Adolfo Garcı́a-Sastre, Robert G. Roeder, Alexander Tarakhovsky - Nature 2012 cited by 318
- Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis
Authors: Paul Delgado-Olguı́n, Yu Huang, Xue Li, Danos C. Christodoulou, Christine E. Seidman, J.G. Seidman, Alexander Tarakhovsky, Benoit G. Bruneau - Nature Genetics 2012 cited by 254
- Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response
Authors: Terry Fang, Uwe Schaefer, Ingrid Mecklenbräuker, Astrid Stienen, Scott Dewell, Marie S. Chen, Inmaculada Rioja, Valentino Parravicini, Rab K. Prinjha, Rohit Chandwani, Margaret R. MacDonald, Kevin Lee, Charles M. Rice, Alexander Tarakhovsky - The Journal of Experimental Medicine 2012 cited by 167
- Epigenetic drug discovery: breaking through the immune barrier
Authors: David F. Tough, Paul P. Tak, Alexander Tarakhovsky, Rab K. Prinjha - Nature Reviews Drug Discovery 2016 cited by 158
