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David A. Largaespada

Active 1993–2024

98
Papers
22,077
Citations
65
h-index
94
i10-index

Citations

Citations per year for David A. Largaespada1984: 1 citations1987: 1 citations1993: 4 citations1994: 35 citations1995: 50 citations1996: 72 citations1997: 111 citations1998: 86 citations1999: 97 citations2000: 74 citations2001: 91 citations2002: 113 citations2003: 243 citations2004: 247 citations2005: 303 citations2006: 270 citations2007: 239 citations2008: 188 citations2009: 234 citations2010: 250 citations2011: 234 citations2012: 240 citations2013: 331 citations2014: 239 citations2015: 236 citations2016: 216 citations2017: 244 citations2018: 185 citations2019: 573 citations2020: 614 citations2021: 459 citations2022: 391 citations2023: 259 citations2024: 383 citations2025: 137 citations2026: 3 citations1985–1986: no citations, so these years are not shown1988–1992: no citations, so these years are not shown

Citation sources

Countries

World map of the countries and regions citing this authorUnited States: 3,302 citing papers, 33.6% of this breakdownChina: 1,070 citing papers, 10.9% of this breakdownGermany: 645 citing papers, 6.6% of this breakdownUnited Kingdom: 627 citing papers, 6.4% of this breakdownJapan: 428 citing papers, 4.3% of this breakdownItaly: 379 citing papers, 3.9% of this breakdownCanada: 323 citing papers, 3.3% of this breakdownFrance: 321 citing papers, 3.3% of this breakdownSpain: 226 citing papers, 2.3% of this breakdownNetherlands: 226 citing papers, 2.3% of this breakdownAustralia: 209 citing papers, 2.1% of this breakdownSwitzerland: 142 citing papers, 1.4% of this breakdown
0%33.6%Other 19.6%

Institutions

Fields

  • Medicine47.4%
  • Biochemistry, Genetics and Molecular Biology40.2%
  • Immunology and Microbiology6.8%
  • Agricultural and Biological Sciences1.9%
  • Neuroscience1.6%
  • Engineering0.9%
  • Other1.2%

Topics

  • Mesenchymal stem cell research5.6%
  • CRISPR and Genetic Engineering2.8%
  • Pluripotent Stem Cells Research2.3%
  • Tissue Engineering and Regenerative Medicine2.2%
  • Cancer-related molecular mechanisms research2.2%
  • Cancer Genomics and Diagnostics2.1%
  • Other82.8%

Coauthors

All papers

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  1. Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

    Authors: Partow Kebriaei, Harjeet Singh, M. Helen Huls, Matthew J. Figliola, Roland L. Bassett, Simon Olivares, Bipulendu Jena, Margaret J. Dawson, Pappanaicken R. Kumaresan, Shihuang Su, Sourindra N. Maiti, Jianliang Dai, Branden S. Moriarity, Marie-Andrée Forget, Vladimir Senyukov, Aaron Orozco, Tingting Liu, Jessica M McCarty, Rineka N. Jackson, Judy S. Moyes, Gabriela Rondón, Muzaffar H. Qazilbash, Stefan O. Ciurea, Amin M. Alousi, Yago Nieto, Katy Rezvani, David Marín, Uday Popat, Chitra Hosing, Elizabeth J. Shpall, Hagop M. Kantarjian, Michael J. Keating, William G. Wierda, Kim‐Anh Do, David A. Largaespada, Dean A. Lee, Perry B. Hackett, Richard E. Champlin, Laurence J.N. Cooper - Journal of Clinical Investigation 2016 cited by 504

  2. Recurrent R-spondin fusions in colon cancer

    Authors: Somasekar Seshagiri, Eric Stawiski, Steffen Durinck, Zora Modrušan, Elaine E. Storm, Caitlin B. Conboy, Subhra Chaudhuri, Yinghui Guan, Vasantharajan Janakiraman, Bijay S. Jaiswal, Joseph Guillory, Connie Ha, Gerrit J.P. Dijkgraaf, Jeremy Stinson, Florian Gnad, Melanie A. Huntley, Jeremiah D. Degenhardt, Peter M. Haverty, Richard Bourgon, Weiru Wang, Hartmut Koeppen, Robert Gentleman, Timothy K. Starr, Zemin Zhang, David A. Largaespada, Thomas D. Wu, Frédéric J. de Sauvage - Nature 2012 cited by 982

  3. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

    Authors: Ignacio Varela, Patrick Tarpey, Keiran Raine, Dachuan Huang, Choon Kiat Ong, Philip Stephens, Helen Davies, David Jones, Meng Lin, Jon W. Teague, Graham R. Bignell, Adam P. Butler, Juok Cho, Gillian L. Dalgliesh, Danushka Galappaththige, Chris Greenman, Claire Hardy, Mingming Jia, Calli Latimer, King Wai Lau, John L. Marshall, Stuart McLaren, Andrew Menzies, Laura Mudie, Lucy Stebbings, David A. Largaespada, Lodewyk F.A. Wessels, Stephane Richard, Richard J. Kahnoski, John Anema, David A. Tuveson, Pedro A. Pérez–Mancera, Ville Mustonen, Andrej Fischer, David J. Adams, Alistair G. Rust, Waraporn Chan-on, Chutima Subimerb, Karl Dykema, Kyle Furge, Peter J. Campbell, Bin Tean Teh, Michael R. Stratton, P. Andrew Futreal - Nature 2011 cited by 1,291

  4. RETRACTED ARTICLE: Pluripotency of mesenchymal stem cells derived from adult marrow

    Authors: Yuehua Jiang, Balkrishna Jahagirdar, R. Lee Reinhardt, Robert E. Schwartz, C. Dirk Keene, Xilma R. Ortiz‐González, Morayma Reyes, Todd Lenvik, Troy C. Lund, Mark Blackstad, Jingbo Du, Sara Aldrich, Aaron Lisberg, Walter C. Low, David A. Largaespada, Catherine M. Verfaillie - Nature 2002 cited by 5,535

  5. PVT1 dependence in cancer with MYC copy-number increase

    Authors: Yuen‐Yi Tseng, Branden S. Moriarity, Wuming Gong, Ryutaro Akiyama, Ashutosh Tiwari, Hiroko Kawakami, Peter Ronning, Brian Reuland, Kacey L. Guenther, Thomas C. Beadnell, Jaclyn Essig, George M. Otto, M. Gerard O’Sullivan, David A. Largaespada, Kathryn L. Schwertfeger, York Marahrens, Yasuhiko Kawakami, Anindya Bagchi - Nature 2014 cited by 743

  6. Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

    Authors: Marc Zuckermann, Volker Hovestadt, Christiane B. Knobbe‐Thomsen, Marc Zapatka, Paul A. Northcott, Kathrin Schramm, Jelena Belic, David Jones, Barbara R. Tschida, Branden S. Moriarity, David A. Largaespada, Martine F. Roussel, Andrey Korshunov, Guido Reifenberger, Stefan M. Pfister, Peter Lichter, Daisuke Kawauchi, Jan Gronych - Nature Communications 2015 cited by 301

  7. APOBEC3A catalyzes mutation and drives carcinogenesis in vivo

    Authors: Emily K. Law, Rena Levin-Klein, Matthew C. Jarvis, Hyoung Kim, Prokopios P. Argyris, Michael A. Carpenter, Gabriel J. Starrett, Nuri A. Temiz, Lindsay K. Larson, Cameron Durfee, Michael B. Burns, Rachel I. Vogel, Spyridon Stavrou, Alexya N. Aguilera, Sandra Wagner, David A. Largaespada, Timothy K. Starr, Susan R. Ross, Reuben S. Harris - The Journal of Experimental Medicine 2020 cited by 154

  8. Harnessing a High Cargo-Capacity Transposon for Genetic Applications in Vertebrates

    Authors: Darius Balčiūnas, Kirk J. Wangensteen, Andrew Wilber, Jason Bell, Aron M. Geurts, Sridhar Sivasubbu, Xin Wang, Perry B. Hackett, David A. Largaespada, R. Scott McIvor, Stephen C. Ekker - PLoS Genetics 2006 cited by 338

  9. CRISPR/Cas9 library screening for drug target discovery

    Authors: Morito Kurata, Kouhei Yamamoto, Branden S. Moriarity, Masanobu Kitagawa, David A. Largaespada - Journal of Human Genetics 2017 cited by 111

  10. Radiation Therapy and Myeloid-Derived Suppressor Cells: Breaking Down Their Cancerous Partnership

    Authors: Kyra M. Boorsma Bergerud, Matthew Berkseth, Drew M. Pardoll, Sudipto Ganguly, Lawrence Kleinberg, Jessica Lawrence, David J. Odde, David A. Largaespada, Stephanie A. Terezakis, Lindsey Sloan - International Journal of Radiation Oncology*Biology*Physics 2023 cited by 41

  11. Cloning of the Murine Thymic Stromal Lymphopoietin (Tslp) Receptor

    Authors: Linda Park, Unja Martin, Kirsten E. Garka, Brian Gliniak, James P. Di Santo, Werner Müller, David A. Largaespada, Neal G. Copeland, Nancy A. Jenkins, Andrew G. Farr, Steven F. Ziegler, Philip Morrissey, Raymond J. Paxton, John E. Sims - The Journal of Experimental Medicine 2000 cited by 415

  12. Single-Cell Gene Expression Analyses Reveal Distinct Self-Renewing and Proliferating Subsets in the Leukemia Stem Cell Compartment in Acute Myeloid Leukemia

    Authors: Karen Sachs, Aaron L. Sarver, Klara E. Noble-Orcutt, Rebecca S. LaRue, Marie Lue Antony, Daniel Chang, Yoonkyu Lee, Connor M. Navis, Alexandria L. Hillesheim, Ian Nykaza, Ngoc A. Ha, Conner J. Hansen, Fatma Keklik Karadağ, Rachel J. Bergerson, Michael R. Verneris, Matthew M. Meredith, Matthew Schomaker, Michael A. Linden, Chad L. Myers, David A. Largaespada, Zohar Sachs - Cancer Research 2019 cited by 73

  13. Social stress shortens lifespan in mice

    Authors: Maria Razzoli, Kewir Nyuyki‐Dufe, Allison Gurney, Connor Erickson, Jacob McCallum, Nicholas Spielman, Marta Marzullo, Jessica Patricelli, Morito Kurata, Emily A. Pope, Chadi Touma, Rupert Palme, David A. Largaespada, David B. Allison, Alessandro Bartolomucci - Aging Cell 2018 cited by 123

  14. Clonal selection drives genetic divergence of metastatic medulloblastoma

    Authors: Xiaochong Wu, Paul A. Northcott, Adrian M. Dubuc, Adam J. Dupuy, David Shih, Hendrik Witt, Sidney Croul, Éric Bouffet, Daniel W. Fults, Charles G. Eberhart, Livia Garzia, Timothy Van Meter, David Zagzag, Nada Jabado, Jeremy Schwartzentruber, Jacek Majewski, Todd E. Scheetz, Stefan M. Pfister, Andrey Korshunov, Xiao‐Nan Li, Stephen W. Scherer, Yoon-Jae Cho, Keiko Akagi, Tobey J. MacDonald, Jan Köster, Martin G. McCabe, Aaron L. Sarver, V. Peter Collins, William A. Weiss, David A. Largaespada, Lara S. Collier, Michael D. Taylor - Nature 2012 cited by 412

  15. Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities

    Authors: Suganth Suppiah, Sheila Mansouri, Yasin Mamatjan, Jeffrey Liu, Minu Bhunia, Vikas Patil, Prisni Rath, Bharati Mehani, Pardeep Heir, Severa Bunda, Germán L. Vélez‐Reyes, Olivia Singh, Nazanin Ijad, Neda Pirouzmand, Tatyana Dalcourt, Ying Meng, Shirin Karimi, Qingxia Wei, Farshad Nassiri, Trevor J. Pugh, Gary D. Bader, Kenneth Aldape, David A. Largaespada, Gelareh Zadeh - Nature Communications 2023 cited by 45

  16. Evolution of the clinical-stage hyperactive TcBuster transposase as a platform for robust non-viral production of adoptive cellular therapies

    Authors: Joseph G. Skeate, Emily J. Pomeroy, Nicholas J. Slipek, Bryan J. Jones, Bryce Wick, Jae‐Woong Chang, Walker S. Lahr, Erin M. Stelljes, Xiaobai Patrinostro, Blake Barnes, Trevor Zarecki, Joshua Krueger, Jacob E. Bridge, Gabrielle M. Robbins, Madeline D. McCormick, John R. Leerar, Kari T. Wenzel, Kathlyn Hornberger, Kirsti L. Walker, G. Dalton Smedley, David A. Largaespada, Neil Otto, Beau R. Webber, Branden S. Moriarity - Molecular Therapy 2024 cited by 26

  17. De novo Induction of Genetically Engineered Brain Tumors in Mice Using Plasmid DNA

    Authors: Stephen M. Wiesner, Stacy A. Decker, Jon D. Larson, Katya Ericson, Colleen L. Forster, Jose L. Gallardo, Chunmei Long, Zachary L. Demorest, Edward A. Zamora, Walter C. Low, Karen S. SantaCruz, David A. Largaespada, John R. Ohlfest - Cancer Research 2009 cited by 183

  18. CFTR is a tumor suppressor gene in murine and human intestinal cancer

    Authors: B L N Than, Janneke F. Linnekamp, Timothy K. Starr, David A. Largaespada, A Rod, Ying Zhang, V. Bruner, Juan E. Abrahante, Abby C. Schumann, Tiana Luczak, A Niemczyk, M. G. O'Sullivan, Jan Paul Medema, Remond J.A. Fijneman, Gerrit A. Meijer, Evert van den Broek, Craig A. Hodges, Patricia M. Scott, Louis Vermeulen, R. Cormier - Oncogene 2016 cited by 176

  19. RAD-TGTs: high-throughput measurement of cellular mechanotype via rupture and delivery of DNA tension probes

    Authors: Matthew R. Pawlak, Adam T. Smiley, María Paz Ramírez, Marcus D. Kelly, Ghaidan A. Shamsan, Sarah M. Anderson, Branden A. Smeester, David A. Largaespada, David J. Odde, Wendy R. Gordon - Nature Communications 2023 cited by 29

  20. The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

    Authors: Australian Pancreatic Cancer Genome Initiative, Pedro A. Pérez–Mancera, Alistair G. Rust, Louise van der Weyden, Glen Kristiansen, Allen Li, Aaron L. Sarver, Kevin A.T. Silverstein, Robert Grützmann, Daniela Aust, Petra Rümmele, Thomas Knösel, Colin Herd, Derek L. Stemple, Ross Kettleborough, Jacqueline A. Brosnan‐Cashman, Ang Li, Richard A. Morgan, Spencer Knight, Jun Yu, Shane Stegeman, Lara S. Collier, Jelle J. ten Hoeve, Jeroen de Ridder, Alison P. Klein, Michael Goggins, Ralph H. Hruban, David K. Chang, Andrew V. Biankin, Sean M. Grimmond, Lodewyk F.A. Wessels, Stephen A. Wood, Christine A. Iacobuzio–Donahue, Christian Pilarsky, David A. Largaespada, David J. Adams, David A. Tuveson - Nature 2012 cited by 317

  21. Extensive somatic L1 retrotransposition in colorectal tumors

    Authors: Szilvia Sólyom, Adam D. Ewing, Eric P. Rahrmann, Tara T. Doucet-O’Hare, Heather H. Nelson, Michael B. Burns, Reuben S. Harris, David F. Sigmon, Alex M. Casella, Bracha Erlanger, Sarah J. Wheelan, Kyle R. Upton, Ruchi Shukla, Geoffrey J. Faulkner, David A. Largaespada, Haig H. Kazazian - Genome Research 2012 cited by 281

  22. Targeted Inhibition of the Dual Specificity Phosphatases DUSP1 and DUSP6 Suppress MPNST Growth via JNK

    Authors: Annmarie Ramkissoon, Katherine E. Chaney, David Milewski, Kyle B. Williams, Rory L. Williams, Kwangmin Choi, Adam Miller, Tanya V. Kalin, Joseph G. Pressey, Sara Szabo, Mohammad Azam, David A. Largaespada, Nancy Ratner - Clinical Cancer Research 2019 cited by 78

  23. Multivalent, Bispecific αB7-H3-αCD3 Chemically Self-Assembled Nanorings Direct Potent T Cell Responses against Medulloblastoma

    Authors: Ellie A. Mews, Pauline J. Beckmann, Mahathi Patchava, Yiao Wang, David A. Largaespada, Carston R. Wagner - ACS Nano 2022 cited by 22

  24. Mutation of Unique Region of Bruton's Tyrosine Kinase in Immunodeficient XID Mice

    Authors: David J. Rawlings, Douglas C. Saffran, Satoshi Tsukada, David A. Largaespada, J. Christopher Grimaldi, Lucie Cohen, Randolph N. Mohr, J. Fernando Bazán, Maureen Howard, Neal G. Copeland, Nancy A. Jenkins, Owen N. Witte - Science 1993 cited by 869