Paul J. Coffer
Active 1991–2025
- 87
- Papers
- 25,381
- Citations
- 78
- h-index
- 84
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology52.9%
- Medicine29.3%
- Immunology and Microbiology11.6%
- Neuroscience2.4%
- Nursing1.2%
- Agricultural and Biological Sciences1%
- Other1.6%
Topics
- Gut microbiota and health6.6%
- Immune Cell Function and Interaction3.4%
- PI3K/AKT/mTOR signaling in cancer3.1%
- FOXO transcription factor regulation2.9%
- Protein Kinase Regulation and GTPase Signaling2.2%
- T-cell and B-cell Immunology2.1%
- Other79.7%
Coauthors
- Leo Koenderman15
- Boudewijn Burgering11
- Jorg van Loosdregt11
- Cornelieke Pals9
- Michal Mokrý8
- Berent J. Prakken7
- Eric W.‐F. Lam7
- Jan‐Willem J. Lammers7
- Sebastiaan J. Vastert7
- Enric Mocholí6
- Ruben van Boxtel6
- Stephin J. Vervoort6
- Dietmar M. Zaiss5
- Kristan E. van der Vos5
- Niels Geijsen5
- Pascale F. Dijkers5
- René H. Medema5
- Alice J.A.M. Sijts4
- Ana Rita Lourenço4
- Jan A. M. Raaijmakers4
- Jeffrey M. Beekman4
- Kim U. Birkenkamp4
- Veerle Fleskens4
- W. Kruijer4
All papers
- Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
Authors: Nicholas Arpaia, Clarissa Campbell, Xiying Fan, Stanislav Dikiy, Joris van der Veeken, Paul deRoos, Hui Liu, Justin R. Cross, Klaus Pfeffer, Paul J. Coffer, Alexander Y. Rudensky - Nature 2013 cited by 4,797
- Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro
Authors: Luciënne A. Vonk, Sanne F. J. van Dooremalen, Nalan Liv, Judith Klumperman, Paul J. Coffer, Daniël B.F. Saris, Magdalena J. Lorenowicz - Theranostics 2017 cited by 345
- Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
Authors: Geert J.P.L. Kops, Tobias B. Dansen, Paulien E. Polderman, Ingrid Saarloos, K.W.A. Wirtz, Paul J. Coffer, Ting-T. Huang, Johannes L. Bos, René H. Medema, Boudewijn Burgering - Nature 2002 cited by 1,570
- Amphiregulin Enhances Regulatory T Cell-Suppressive Function via the Epidermal Growth Factor Receptor
Authors: Dietmar M. Zaiss, Jorg van Loosdregt, Andrea Gorlani, Cornelis P. J. Bekker, Andrea Gröne, Maria Sibilia, Paul M.P. van Bergen en Henegouwen, Rob C. Roovers, Paul J. Coffer, Alice J.A.M. Sijts - Immunity 2013 cited by 405
- Colorectal Cancer-Infiltrating Regulatory T Cells: Functional Heterogeneity, Metabolic Adaptation, and Therapeutic Targeting
Authors: Sonia Aristín Revilla, Onno Kranenburg, Paul J. Coffer - Frontiers in Immunology 2022 cited by 88
- Stabilization of the Transcription Factor Foxp3 by the Deubiquitinase USP7 Increases Treg-Cell-Suppressive Capacity
Authors: Jorg van Loosdregt, Veerle Fleskens, Juan Fu, Arjan B. Brenkman, Cornelis P. J. Bekker, Cornelieke Pals, Jenny Meerding, Celia R. Berkers, Joseph Barbi, Andrea Gröne, Alice J.A.M. Sijts, Madelon M. Maurice, Eric Kalkhoven, Berent J. Prakken, Huib Ovaa, Fan Pan, Dietmar M. Zaiss, Paul J. Coffer - Immunity 2013 cited by 311
- Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapy
Authors: Lianne van de Laar, Paul J. Coffer, Andrea M. Woltman - Blood 2012 cited by 344
- Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization
Authors: Jorg van Loosdregt, Yvonne Vercoulen, Teun Guichelaar, Yoony Y. J. Gent, Jeffrey M. Beekman, Olivier van Beekum, Arjan B. Brenkman, DirkJan Hijnen, Tuna Mutis, Eric Kalkhoven, Berent J. Prakken, Paul J. Coffer - Blood 2009 cited by 375
- PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation
Authors: Alessandra Petrelli, Gerdien Mijnheer, David P. Hoytema van Konijnenburg, Marlot van der Wal, Barbara Giovannone, Enric Mocholí, Nadia Vazirpanah, Jasper Broen, DirkJan Hijnen, Bas Oldenburg, Paul J. Coffer, Sebastiaan J. Vastert, Berent J. Prakken, Eric Spierings, Aridaman Pandit, Michal Mokrý, Femke van Wijk - Journal of Clinical Investigation 2018 cited by 121
- A tumor suppressor role for C/EBPα in solid tumors: more than fat and blood
Authors: Ana Rita Lourenço, Paul J. Coffer - Oncogene 2017 cited by 103
- Canonical Wnt Signaling Negatively Modulates Regulatory T Cell Function
Authors: Jorg van Loosdregt, Veerle Fleskens, Machteld M. Tiemessen, Michal Mokrý, Ruben van Boxtel, Jenny Meerding, Cornelieke Pals, Dorota Kurek, Miranda R.M. Baert, Eveline M. Delemarre, Andrea Gröne, Marian J.A. Groot Koerkamp, Alice J.A.M. Sijts, Edward E. S. Nieuwenhuis, Madelon M. Maurice, Johan H. van Es, Derk ten Berge, Frank C. P. Holstege, Frank J. T. Staal, Dietmar M. Zaiss, Berent J. Prakken, Paul J. Coffer - Immunity 2013 cited by 240
- Pyruvate metabolism controls chromatin remodeling during CD4+ T cell activation
Authors: Enric Mocholí, Laura Russo, Keshav Gopal, Andrew G. Ramstead, Sophia M. Hochrein, Harmjan R. Vos, Geert Geeven, Adeolu Adegoke, Anna T. Hoekstra, Robert M. van Es, José M. Ramos Pittol, Sebastiaan J. Vastert, Jared Rutter, Timothy R. D. J. Radstake, Jorg van Loosdregt, Celia R. Berkers, Michal Mokrý, Colin C. Anderson, Ryan M. O’Connell, Martin Vaeth, John R. Ussher, Boudewijn Burgering, Paul J. Coffer - Cell Reports 2023 cited by 39
- Modulation of glutamine metabolism by the PI(3)K–PKB–FOXO network regulates autophagy
Authors: Kristan E. van der Vos, Pernilla Eliasson, Tassula Proikas‐Cezanne, Stephin J. Vervoort, Ruben van Boxtel, Marrit Putker, Iris J. van Zutphen, Mario Mauthe, Sebastian Zellmer, Cornelieke Pals, Liesbeth P. Verhagen, Marian J.A. Groot Koerkamp, A. Koen Braat, Tobias B. Dansen, Frank C. P. Holstege, Rolf Gebhardt, Boudewijn Burgering, Paul J. Coffer - Nature Cell Biology 2012 cited by 246
- Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency
Authors: Jorik M. van Rijn, Rico Chandra Ardy, Zarife Kuloğlu, Bettina Härter, Désirée Y. van Haaften–Visser, Hubert P. J. van der Doef, Marliek van Hoesel, Aydan Kansu, Anke H.M. van Vugt, Marini Thian, Freddy Kokke, Ana Krolo, Meryem Keçeli Başaran, Neslihan Gürcan Kaya, Aysel Ünlüsoy Aksu, Buket Dalgıç, Figen Özçay, Zeren Barış, Renate Kain, Edwin C.A. Stigter, Klaske D. Lichtenbelt, Maarten P.G. Massink, Karen Duran, Joke B.G.M Verheij, Dorien Lugtenberg, Peter G. J. Nikkels, Henricus G.F. Brouwer, Henkjan J. Verkade, René Scheenstra, Bart Spee, Edward E. S. Nieuwenhuis, Paul J. Coffer, Andreas Janecke, Gijs van Haaften, Roderick H.J. Houwen, Thomas Müller, Sabine Middendorp, Kaan Boztuǧ - Gastroenterology 2018 cited by 122
- Activation of autophagy by FOXO3 regulates redox homeostasis during osteogenic differentiation
Authors: Maria Catalina Gomez‐Puerto, Liesbeth P. Verhagen, A. Koen Braat, Eric W.‐F. Lam, Paul J. Coffer, Magdalena J. Lorenowicz - Autophagy 2016 cited by 116
- FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
Authors: Jonathan Gilley, Paul J. Coffer, Jonathan Ham - The Journal of Cell Biology 2003 cited by 641
- The Forkhead Transcription Factor FoxO Regulates Transcription of p27 Kip1 and Bim in Response to IL-2
Authors: Marie Ståhl, Pascale F. Dijkers, Geert J.P.L. Kops, Susanne M.A. Lens, Paul J. Coffer, Boudewijn Burgering, René H. Medema - The Journal of Immunology 2002 cited by 575
- MAPK signaling pathways in the regulation of hematopoiesis
Authors: Christian R. Geest, Paul J. Coffer - Journal of Leukocyte Biology 2009 cited by 263
- The role of SRY-related HMG box transcription factor 4 (SOX4) in tumorigenesis and metastasis: friend or foe?
Authors: Stephin J. Vervoort, Ruben van Boxtel, Paul J. Coffer - Oncogene 2012 cited by 201
- Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion
Authors: Carlos M. Minutti, Sebastian Drube, Natalie Blair, Christian Schwartz, Jame McCrae, Andrew N. J. McKenzie, Thomas Kamradt, Michal Mokrý, Paul J. Coffer, Maria Sibilia, Alice J.A.M. Sijts, Padraic G. Fallon, Rick M. Maizels, Dietmar M. Zaiss - Immunity 2017 cited by 106
- Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
Authors: Boudewijn Burgering, Paul J. Coffer - Nature 1995 cited by 2,109
- Control of Cell Cycle Exit and Entry by Protein Kinase B-Regulated Forkhead Transcription Factors
Authors: Geert J.P.L. Kops, René H. Medema, Janet Glassford, Marieke Essers, Pascale F. Dijkers, Paul J. Coffer, Eric W.‐F. Lam, Boudewijn Burgering - Molecular and Cellular Biology 2002 cited by 442
- The Transcription of FOXO Genes Is Stimulated by FOXO3 and Repressed by Growth Factors
Authors: Ahmed Essaghir, Nicolas Dif, Catherine Y. Marbehant, Paul J. Coffer, Jean‐Baptiste Demoulin - Journal of Biological Chemistry 2009 cited by 220
- Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression
Authors: Janneke G. C. Peeters, Stephin J. Vervoort, Sander Tan, Gerdien Mijnheer, Sytze de Roock, Sebastiaan J. Vastert, Edward E. S. Nieuwenhuis, Femke van Wijk, Berent J. Prakken, Menno P. Creyghton, Paul J. Coffer, Michal Mokrý, Jorg van Loosdregt - Cell Reports 2015 cited by 106
