Piotr Siciński
Active 1988–2024
- Also published as
- Piotr Sicinski
- 78
- Papers
- 22,168
- Citations
- 69
- h-index
- 78
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology47%
- Medicine43.1%
- Immunology and Microbiology3.7%
- Neuroscience2.3%
- Agricultural and Biological Sciences1%
- Pharmacology, Toxicology and Pharmaceutics0.5%
- Other2.4%
Topics
- Cancer-related Molecular Pathways7.3%
- Advanced Breast Cancer Therapies3.5%
- Epigenetics and DNA Methylation3.2%
- Ubiquitin and proteasome pathways2.9%
- Microtubule and mitosis dynamics2.8%
- Cancer Immunotherapy and Biomarkers2%
- Other78.3%
Coauthors
- Yan Geng25
- Anne Fassl15
- Ewa Sicińska12
- Roderick T. Bronson10
- Steven P. Gygi9
- Wenyi Wei8
- Wojciech Michowski8
- Yoon Jong Choi8
- Qunyan Yu7
- Agnieszka Zagożdżon6
- Chen Chu6
- Hiroyuki Inuzuka6
- Jan M. Suski6
- Kornélia Polyák6
- Tobias Otto6
- Bojana Jovanović5
- Humphrey Gardner5
- Jinfang Zhang5
- Joel M. Chick5
- Robert A. Weinberg5
- Aleksandra Kołodziejczyk4
- Gordon J. Freeman4
- Haizhen Wang4
- Jean J. Zhao4
All papers
- Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance
Authors: Jinfang Zhang, Xia Bu, Haizhen Wang, Yasheng Zhu, Yan Geng, Naoe Taira Nihira, Yuyong Tan, Yanpeng Ci, Fei Wu, Xiangpeng Dai, Jianping Guo, Yuhan Huang, Caoqi Fan, Shancheng Ren, Yinghao Sun, Gordon J. Freeman, Piotr Siciński, Wenyi Wei - Nature 2017 cited by 1,049
- Cell cycle proteins as promising targets in cancer therapy
Authors: Tobias Otto, Piotr Siciński - Nature reviews. Cancer 2017 cited by 1,904
- CDK4 and CDK6 kinases: From basic science to cancer therapy
Authors: Anne Fassl, Yan Geng, Piotr Siciński - Science 2022 cited by 467
- Targeting cell-cycle machinery in cancer
Authors: Jan M. Suski, Marcin Braun, Vladislav Strmiska, Piotr Siciński - Cancer Cell 2021 cited by 568
- Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy
Authors: Yang Gao, Naoe Taira Nihira, Xia Bu, Chen Chu, Jinfang Zhang, Aleksandra Kołodziejczyk, Yizeng Fan, Ngai Ting Chan, Leina Ma, Jing Liu, Dong Wang, Xiaoming Dai, Huadong Liu, Masaya Ono, Akira Nakanishi, Hiroyuki Inuzuka, Brian J. North, Yu-Han Huang, Samanta Sharma, Yan Geng, Wei Xu, X. Shirley Liu, Lei Li, Yoshio Miki, Piotr Siciński, Gordon J. Freeman, Wenyi Wei - Nature Cell Biology 2020 cited by 393
- The cell cycle in stem cell proliferation, pluripotency and differentiation
Authors: Lijun Liu, Wojciech Michowski, Aleksandra Kołodziejczyk, Piotr Siciński - Nature Cell Biology 2019 cited by 431
- Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1
Authors: Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song, Min Liu, Jianlin Lu, Jianping Liu, Chen Chu, Min Wang, Huibing Wang, Huyan Meng, Hui Liu, Yuan Zhuang, Xingxing Xie, Fabin Dang, Dongxian Guan, Yuqin Men, Shuwen Jiang, Cong Jiang, Xiaoming Dai, Jing Liu, Zhen Wang, Peiqiang Yan, Jingchao Wang, Zhenbo Tu, Mrigya Babuta, Emily C. Erickson, Alissandra L. Hillis, Christian C. Dibble, John M. Asara, Gyongy Szabo, Piotr Siciński, Ji Miao, Yu-Ru Lee, Lifeng Pan, Reuben J. Shaw, Junying Yuan, Wenyi Wei - Science 2023 cited by 118
- KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance
Authors: Kunihiko Hinohara, Hua‐Jun Wu, Sébastien Vigneau, Thomas O. McDonald, Kyomi J. Igarashi, Kimiyo N. Yamamoto, Thomas Madsen, Anne Fassl, Shawn B. Egri, Malvina Papanastasiou, Lina Ding, Guillermo Peluffo, Ofir Cohen, Stephen C. Kales, Madhu Lal‐Nag, Ganesha Rai, David J. Maloney, Ajit Jadhav, Anton Simeonov, Nikhil Wagle, Myles Brown, Alexander Meissner, Piotr Siciński, Jacob D. Jaffe, Rinath Jeselsohn, Alexander A. Gimelbrant, Franziska Michor, Kornélia Polyák - Cancer Cell 2018 cited by 254
- Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases
Authors: Per Hydbring, Marcos Malumbres, Piotr Siciński - Nature Reviews Molecular Cell Biology 2016 cited by 538
- Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors
Authors: Shom Goel, Qi Wang, April C. Watt, Sara M. Tolaney, Deborah Dillon, Wěi Li, Susanne Ramm, Adam C. Palmer, Haluk Yuzugullu, Vinay Varadan, David Tuck, Lyndsay N. Harris, Kwok‐Kin Wong, X. Shirley Liu, Piotr Siciński, Eric P. Winer, Ian E. Krop, Jean J. Zhao - Cancer Cell 2016 cited by 488
- Cyclin D activates the Rb tumor suppressor by mono-phosphorylation
Authors: Anil Narasimha, Manuel Kaulich, Gary S. Shapiro, Yoon Jong Choi, Piotr Siciński, Steven F. Dowdy - eLife 2014 cited by 464
- JAK–STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States
Authors: Laura E. Stevens, Guillermo Peluffo, Xintao Qiu, Daniel Temko, Anne Fassl, Zheqi Li, Anne Trinh, Marco Seehawer, Bojana Jovanović, Maša Alečković, Callahan M. Wilde, Renee C. Geck, Shaokun Shu, Natalie L. Kingston, Nicholas W. Harper, Vanessa Almendro, Alanna L. Pyke, Shawn B. Egri, Malvina Papanastasiou, Kendell Clement, Ningxuan Zhou, Sarah R. Walker, Jacqueline Salas, So Yeon Park, David A. Frank, Alexander Meissner, Jacob D. Jaffe, Piotr Siciński, Alex Toker, Franziska Michor, Henry W. Long, Beth Overmoyer, Kornélia Polyák - Cancer Research 2022 cited by 101
- PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity
Authors: Jing Liu, Xia Bu, Chen Chu, Xiaoming Dai, John M. Asara, Piotr Siciński, Gordon J. Freeman, Wenyi Wei - Nature Communications 2023 cited by 75
- Cyclin E in normal physiology and disease states
Authors: Chen Chu, Yan Geng, Yu Zhou, Piotr Siciński - Trends in Cell Biology 2021 cited by 162
- A Systematic Screen for CDK4/6 Substrates Links FOXM1 Phosphorylation to Senescence Suppression in Cancer Cells
Authors: Lars Anders, Nan Rosemary Ke, Per Hydbring, Yoon Jong Choi, Hans R. Widlund, Joel M. Chick, Huili Zhai, Marc Vidal, Stephen P. Gygi, Pascal Falter‐Braun, Piotr Siciński - Cancer Cell 2011 cited by 550
- CDC7-independent G1/S transition revealed by targeted protein degradation
Authors: Jan M. Suski, Nalin Ratnayeke, Marcin Braun, Tian Zhang, Vladislav Strmiska, Wojciech Michowski, Geylani Can, Antoine Simoneau, Konrad Śnioch, Mikolaj Cup, Caitlin Sullivan, Xiaoji Wu, Joanna Nowacka‐Woszuk, Timothy B. Branigan, Lindsey R. Pack, James A. DeCaprio, Yan Geng, Lee Zou, Steven P. Gygi, Johannes C. Walter, Tobias Meyer, Piotr Siciński - Nature 2022 cited by 94
- Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus
Authors: Pengda Liu, Michael J. Begley, Wojciech Michowski, Hiroyuki Inuzuka, Miriam B. Ginzberg, Daming Gao, Peiling Tsou, Wenjian Gan, Antonella Papa, Byeong Mo Kim, Lixin Wan, Amrik Singh, Bo Zhai, Min Yuan, Zhiwei Wang, Steven P. Gygi, Tae Ho Lee, Kun-Ping Lu, Alex Toker, Pier Paolo Pandolfi, John M. Asara, Marc W. Kirschner, Piotr Siciński, Lewis C. Cantley, Wenyi Wei - Nature 2014 cited by 367
- The metabolic function of cyclin D3–CDK6 kinase in cancer cell survival
Authors: Haizhen Wang, Brandon Nicolay, Joel M. Chick, Xueliang Gao, Yan Geng, Hongliang Ren, Hui Gao, Guizhi Yang, Juliet Williams, Jan M. Suski, Mark A. Keibler, Ewa Sicińska, Ulrike Gerdemann, W. Nicholas Haining, Thomas M. Roberts, Kornélia Polyák, Steven P. Gygi, Nicholas J. Dyson, Piotr Siciński - Nature 2017 cited by 354
- The Molecular Basis of Muscular Dystrophy in the mdx Mouse: a Point Mutation
Authors: Piotr Siciński, Yan Geng, Allan S. Ryder-Cook, Eric A. Barnard, Mark G. Darlison, Pene J. Barnard - Science 1989 cited by 1,225
- Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer
Authors: Jennifer Y. Ge, Shaokun Shu, Mijung Kwon, Bojana Jovanović, Katherine C. Murphy, Anushree C. Gulvady, Anne Fassl, Anne Trinh, Yanan Kuang, Grace A. Heavey, Adrienne Luoma, Cloud P. Paweletz, Aaron R. Thorner, Kai W. Wucherpfennig, Jun Qi, Myles Brown, Piotr Siciński, Thomas O. McDonald, David Pellman, Franziska Michor, Kornélia Polyák - Nature Communications 2020 cited by 95
- Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27
Authors: Lucia García-Gutiérrez, Gabriel Bretones, Ester Molina, Ignacio Aréchaga, Catherine E. Symonds, Juan Carlos Acosta, Rosa Blanco, Adrián Fernández, Leticia Alonso, Piotr Siciński, Mariano Barbacid, David Santamarı́a, Javier León - Scientific Reports 2019 cited by 74
- Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer
Authors: Fabin Dang, Li Nie, Jin Zhou, Kouhei Shimizu, Chen Chu, Zhong Wu, Anne Fassl, Shizhong Ke, Yuangao Wang, Jinfang Zhang, Tao Zhang, Zhenbo Tu, Hiroyuki Inuzuka, Piotr Siciński, Adam J. Bass, Wenyi Wei - Nature Communications 2021 cited by 50
- Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells
Authors: Wojciech Michowski, Joel M. Chick, Chen Chu, Aleksandra Kołodziejczyk, Yichen Wang, Jan M. Suski, Brian J. Abraham, Lars Anders, Daniel S. Day, Lukas Manuel Dunkl, Mitchell Li Cheong Man, Tian Zhang, Phatthamon Laphanuwat, Nickolas A. Bacon, Lijun Liu, Anne Fassl, Samanta Sharma, Tobias Otto, Emanuelle Jecrois, Richard C. Han, Katharine E. Sweeney, Samuele Marro, Marius Wernig, Yan Geng, Alan M Moses, Cheng Li, Steven P. Gygi, Richard A. Young, Piotr Siciński - Molecular Cell 2020 cited by 123
- Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition
Authors: Anne Fassl, Christopher T. Brain, Monther Abu-Remaileh, Iga Stukan, Deborah Butter, Piotr Stępień, Avery Feit, Johann S. Bergholz, Wojciech Michowski, Tobias Otto, Qing Sheng, Alice Loo, Walter Michael, Ralph Tiedt, Carmine De Angelis, Rachel Schiff, Baishan Jiang, Bojana Jovanović, Karolina Nowak, Maria Ericsson, Michael D. Cameron, Nathanael S. Gray, Deborah Dillon, Jean J. Zhao, David M. Sabatini, Rinath Jeselsohn, Myles Brown, Kornélia Polyák, Piotr Siciński - Science Advances 2020 cited by 105
