Adam Siepel
Active 1995–2025
- 68
- Papers
- 26,341
- Citations
- 51
- h-index
- 67
- i10-index
Citations
Citation sources
Countries
Institutions
Fields
- Biochemistry, Genetics and Molecular Biology74.5%
- Agricultural and Biological Sciences7.3%
- Medicine7.1%
- Immunology and Microbiology2.9%
- Neuroscience2.3%
- Environmental Science1.2%
- Other4.7%
Topics
- Genomics and Phylogenetic Studies7.5%
- Genomics and Chromatin Dynamics6.2%
- RNA Research and Splicing5.3%
- RNA and protein synthesis mechanisms5.2%
- Chromosomal and Genetic Variations4.2%
- RNA modifications and cancer4%
- Other67.6%
Coauthors
- Melissa J. Hubisz13
- Ilan Gronau11
- Charles G. Danko9
- David Haussler7
- Noah Dukler7
- Brad Gulko6
- Carlos D. Bustamante6
- John T. Lis6
- W. James Kent6
- Yi-Fei Huang6
- André L. Martins5
- Kate R. Rosenbloom5
- Katherine S. Pollard5
- W. Lee Kraus5
- Armin Scheben4
- Leighton J. Core4
- Leonardo Campagna4
- Sofie R. Salama4
- Webb Miller4
- Adam R. Boyko3
- Andrew D. Kern3
- Craig B. Lowe3
- Dennis Kostka3
- Diego Ortega‐Del Vecchyo3
All papers
- Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes
Authors: Adam Siepel, Gill Bejerano, Jakob Skou Pedersen, Angie S. Hinrichs, Minmei Hou, Kate R. Rosenbloom, Hiram Clawson, John Spieth, LaDeana W. Hillier, Stephen Richards, George M. Weinstock, Richard K. Wilson, Richard A. Gibbs, W. James Kent, Webb Miller, David Haussler - Genome Research 2005 cited by 4,310
- Detection of nonneutral substitution rates on mammalian phylogenies
Authors: Katherine S. Pollard, Melissa J. Hubisz, Kate R. Rosenbloom, Adam Siepel - Genome Research 2009 cited by 2,547
- Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers
Authors: Leighton J. Core, André L. Martins, Charles G. Danko, Colin T. Waters, Adam Siepel, John T. Lis - Nature Genetics 2014 cited by 746
- Fast, scalable prediction of deleterious noncoding variants from functional and population genomic data
Authors: Yi-Fei Huang, Brad Gulko, Adam Siepel - Nature Genetics 2017 cited by 396
- Evolutionary and Biomedical Insights from the Rhesus Macaque Genome
Authors: Richard A. Gibbs, Jeffrey Rogers, Michael G. Katze, Roger E. Bumgarner, George M. Weinstock, Elaine R. Mardis, Karin Remington, Robert L. Strausberg, J. Craig Venter, Richard K. Wilson, Mark A. Batzer, Carlos D. Bustamante, Evan E. Eichler, Matthew W. Hahn, Ross C. Hardison, Kateryna D. Makova, Webb Miller, Aleksandar Milosavljevic, Robert E. Palermo, Adam Siepel, James M. Sikela, Tony Attaway, Stephanie Bell, Kelly E. Bernard, Christian Buhay, Mimi N. Chandrabose, Marvin Dao, Clay Davis, Kimberly D. Delehaunty, Yan Ding, Huyen Dinh, Shannon Dugan-Rocha, Lucinda A. Fulton, Ramatu Ayiesha Gabisi, Toni T. Garner, Jennifer Godfrey, Alicia Hawes, Judith Hernandez, Sandra Hines, Michael Holder, Jennifer Hume, Shalini N. Jhangiani, Vandita Joshi, Ziad Khan, Ewen F. Kirkness, Andrew Cree, R. Gerald Fowler, Sandra Lee, Lora Lewis, Zhangwan Li, Yih-shin Liu, Stephanie Moore, Donna M. Muzny, Lynne V. Nazareth, Dinh Ngoc Ngo, Geoffrey Okwuonu, Grace Pai, David L. Parker, Heidie A. Paul, Cynthia Pfannkoch, Craig Pohl, Yu-Hui Rogers, San Juana Ruiz, Aniko Sabo, Jireh Santibanez, Brian Schneider, Scott M. Smith, Erica Sodergren, Amanda F. Svatek, Teresa R. Utterback, Selina Vattathil, Wesley C. Warren, Courtney White, Asif Chinwalla, Yucheng Feng, Aaron L. Halpern, LaDeana W. Hillier, Xiaoqiu Huang, Pat Minx, Joanne O. Nelson, Kymberlie Pepin, Xiang Qin, Granger G. Sutton, Eli Venter, Brian P. Walenz, John W. Wallis, Kim C. Worley, Shiaw‐Pyng Yang, Steven M. Jones, Marco A. Marra, Mariano Rocchi, Jacqueline E. Schein, Robert Baertsch, Laura Clarke, Miklós Csürös, Jarret Glasscock, R. Alan Harris, Paul Havlak, Andrew Jackson, Huaiyang Jiang and 76 more - Science 2007 cited by 1,451
- An RNA gene expressed during cortical development evolved rapidly in humans
Authors: Katherine S. Pollard, Sofie R. Salama, Nelle Lambert, Marie-Alexandra Lambot, Sandra Coppens, Jakob Skou Pedersen, Sol Katzman, Brian F. King, Courtney Onodera, Adam Siepel, Andrew D. Kern, Colette Dehay, Haller Igel, Manuel Ares, Pierre Vanderhaeghen, David Haussler - Nature 2006 cited by 1,038
- Identification of constrained sequence elements across 239 primate genomes
Authors: Lukas F. K. Kuderna, Jacob C. Ulirsch, Sabrina Mohd Rashid, Mohamed Ameen, Laksshman Sundaram, Glenn Hickey, Anthony J. Cox, Hong Gao, Arvind Kumar, François Aguet, Matthew J. Christmas, Hiram Clawson, Maximilian Haeussler, Mareike C. Janiak, Martin Kuhlwilm, Joseph D. Orkin, Thomas Bataillon, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rouselle, Felipe Ennes Silva, Lídia Águeda, Julie Blanc, Marta Gut, Dorien de Vries, Ian Goodhead, R. Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idriss S. Chuma, Julie E. Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Joshua G. Schraiber, Fabiano Rodrigues de Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Pires Farias, João Valsecchi, Malu Messias, Maria Nazareth Ferreira da Silva, Mihir Trivedi, Rogério Vieira Rossi, Tomas Hrbek, Nicole Andriaholinirina, C. Rabarivola, Alphonse Zaramody, Clifford J. Jolly, Jane E. Phillips‐Conroy, Gregory K. Wilkerson, Christian R. Abee, Joe H. Simmons, Eduardo Fernández‐Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dong‐Dong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D. Keyyu, Sascha Knauf, Minh Đức Lê, Esther Lizano, Stefan Merker, Arcadi Navarro, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C. Kitchener, Dietmar Zinner, Marta Gut, Amanda Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M. D. Beck, Ioannis Karakikes, Ke Wang, Govindhaswamy Umapathy, Christian Roos, Jean P. Boubli, Adam Siepel, Anshul Kundaje, Benedict Paten, Kerstin Lindblad‐Toh, Jeffrey Rogers, Tomàs Marquès‐Bonet, Kyle Kai‐How Farh - Nature 2023 cited by 113
- A high-resolution map of human evolutionary constraint using 29 mammals
Authors: Kerstin Lindblad‐Toh, Manuel Garber, Or Zuk, Michael F. Lin, Brian J. Parker, Stefan Washietl, Pouya Kheradpour, Jason Ernst, Gregory E. Jordan, Evan Mauceli, Lucas D. Ward, Craig B. Lowe, Alisha K. Holloway, Michèle Clamp, Sante Gnerre, Jessica Alföldi, Kathryn Beal, Jean L. Chang, Hiram Clawson, James Cuff, Federica Di Palma, Stephen Fitzgerald, Paul Flicek, Mitchell Guttman, Melissa J. Hubisz, David B. Jaffe, Irwin Jungreis, W. James Kent, Dennis Kostka, Marcia Lara, André L. Martins, Tim Massingham, Ida Moltke, Brian J. Raney, Matthew D. Rasmussen, Jim Robinson, Alexander Stark, Albert J. Vilella, Jiayu Wen, Xiaohui Xie, Michael C. Zody, Kim C. Worley, Christie Kovar, Donna M. Muzny, Richard A. Gibbs, Wesley C. Warren, Elaine R. Mardis, George M. Weinstock, Richard K. Wilson, Ewan Birney, Elliott H. Margulies, Javier Herrero, Eric D. Green, David Haussler, Adam Siepel, Nick Goldman, Katherine S. Pollard, Jakob Skou Pedersen, Eric S. Lander, Manolis Kellis - Nature 2011 cited by 1,228
- Genome-Wide Inference of Ancestral Recombination Graphs
Authors: Matthew D. Rasmussen, Melissa J. Hubisz, Ilan Gronau, Adam Siepel - PLoS Genetics 2014 cited by 445
- Forces Shaping the Fastest Evolving Regions in the Human Genome
Authors: Katherine S. Pollard, Sofie R. Salama, Bryan H. King, Andrew D. Kern, Timothy R. Dreszer, Sol Katzman, Adam Siepel, Jakob Skou Pedersen, Gill Bejerano, Robert Baertsch, Kate R. Rosenbloom, Jim Kent, David Haussler - PLoS Genetics 2006 cited by 548
- Genome Sequencing Highlights the Dynamic Early History of Dogs
Authors: Adam H. Freedman, Ilan Gronau, Rena M. Schweizer, Diego Ortega‐Del Vecchyo, Eunjung Han, Pedro Silva, Marco Galaverni, Zhenxin Fan, Péter Marx, Belén Lorente-Galdós, Holly C. Beale, Óscar Ramírez, Farhad Hormozdiari, Can Alkan, Carles Vilà, Kevin Squire, Eli Geffen, Josip Kusak, Adam R. Boyko, Heidi G. Parker, Clarence Lee, Vasisht Tadigotla, Adam Siepel, Carlos D. Bustamante, Timothy T. Harkins, Stanley F. Nelson, Elaine A. Ostrander, Tomàs Marquès‐Bonet, Robert K. Wayne, John Novembre - PLoS Genetics 2014 cited by 649
- Signaling Pathways Differentially Affect RNA Polymerase II Initiation, Pausing, and Elongation Rate in Cells
Authors: Charles G. Danko, Nasun Hah, Xin Luo, André L. Martins, Leighton J. Core, John T. Lis, Adam Siepel, W. Lee Kraus - Molecular Cell 2013 cited by 353
- Identification of active transcriptional regulatory elements from GRO-seq data
Authors: Charles G. Danko, Stephanie L. Hyland, Leighton J. Core, André L. Martins, Colin T. Waters, Hyung Won Lee, Vivian G. Cheung, W. Lee Kraus, John T. Lis, Adam Siepel - Nature Methods 2015 cited by 272
- A method for calculating probabilities of fitness consequences for point mutations across the human genome
Authors: Brad Gulko, Melissa J. Hubisz, Ilan Gronau, Adam Siepel - Nature Genetics 2015 cited by 304
- A Deep-Learning Approach for Inference of Selective Sweeps from the Ancestral Recombination Graph
Authors: Hussein A. Hejase, Ziyi Mo, Leonardo Campagna, Adam Siepel - Molecular Biology and Evolution 2021 cited by 75
- Long-Read Sequencing Reveals Rapid Evolution of Immunity- and Cancer-Related Genes in Bats
Authors: Armin Scheben, O. Ramos, Melissa Kramer, Sara Goodwin, Sara J. Oppenheim, Daniel J. Becker, Michael C. Schatz, Nancy B. Simmons, Adam Siepel, W. Richard McCombie - Genome Biology and Evolution 2023 cited by 52
- Bayesian inference of ancient human demography from individual genome sequences
Authors: Ilan Gronau, Melissa J. Hubisz, Brad Gulko, Charles G. Danko, Adam Siepel - Nature Genetics 2011 cited by 641
- A Rapid, Extensive, and Transient Transcriptional Response to Estrogen Signaling in Breast Cancer Cells
Authors: Nasun Hah, Charles G. Danko, Leighton J. Core, Joshua J. Waterfall, Adam Siepel, John T. Lis, W. Lee Kraus - Cell 2011 cited by 517
- A Simple Genetic Architecture Underlies Morphological Variation in Dogs
Authors: Adam R. Boyko, Pascale Quignon, Lin Li, Jeffrey J. Schoenebeck, Jeremiah D. Degenhardt, Kirk E. Lohmueller, Keyan Zhao, Abra Brisbin, Heidi G. Parker, Bridgett M. vonHoldt, Michele Cargill, Adam Auton, Andy Reynolds, Abdel G. Elkahloun, Marta G. Castelhano, Dana S. Mosher, Nathan B. Sutter, Gary S. Johnson, John Novembre, Melissa J. Hubisz, Adam Siepel, Robert K. Wayne, Carlos D. Bustamante, Elaine A. Ostrander - PLoS Biology 2010 cited by 516
- Genomic islands of differentiation in a rapid avian radiation have been driven by recent selective sweeps
Authors: Hussein A. Hejase, Ayelet Salman‐Minkov, Leonardo Campagna, Melissa J. Hubisz, Irby J. Lovette, Ilan Gronau, Adam Siepel - National Academy of Sciences, Proceedings of the National Academy of Sciences 2020 cited by 72
- The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease
Authors: Xinxia Peng, Jessica Alföldi, Kevin Gori, Amie J. Eisfeld, Scott R. Tyler, Jennifer Tisoncik-Go, David Brawand, G. Lynn Law, Nives Škunca, Masato Hatta, David J. Gasper, Sara Kelly, Jean Chang, Matthew J. Thomas, Jeremy Johnson, Aaron M. Berlin, Marcia Lara, Pamela Russell, Ross Swofford, Jason Turner-Maier, Sarah Young, Thibaut Hourlier, Bronwen Aken, Steve Searle, Xingshen Sun, Yaling Yi, M. Suresh, Terrence M. Tumpey, Adam Siepel, Samantha M. Wisely, Christophe Dessimoz, Yoshihiro Kawaoka, Susan J. Birren, Kerstin Lindblad‐Toh, Federica Di Palma, John F. Engelhardt, Robert E. Palermo, Michael G. Katze - Nature Biotechnology 2014 cited by 148
- Domain-adaptive neural networks improve supervised machine learning based on simulated population genetic data
Authors: Ziyi Mo, Adam Siepel - PLoS Genetics 2023 cited by 40
- Comparative and demographic analysis of orang-utan genomes
Authors: Devin P. Locke, LaDeana W. Hillier, Wesley C. Warren, Kim C. Worley, Lynne V. Nazareth, Donna M. Muzny, Shiaw‐Pyng Yang, Zhengyuan Wang, Asif Chinwalla, Pat Minx, Makedonka Mitreva, Lisa L. Cook, Kim D. Delehaunty, Catrina C. Fronick, Heather K. Schmidt, Lucinda A. Fulton, Robert S. Fulton, Joanne O. Nelson, Vincent Magrini, Craig Pohl, Tina Graves, Chris Markovic, Andy Cree, Huyen Dinh, Jennifer Hume, Christie Kovar, Gerald Fowler, Gerton Lunter, Stephen Meader, Andreas Heger, Chris P. Ponting, Tomàs Marquès‐Bonet, Can Alkan, Lin Chen, Ze Cheng, Jeffrey M. Kidd, Evan E. Eichler, Simon White, Stephen M. J. Searle, Albert J. Vilella, Yuan Chen, Paul Flicek, Jian Ma, Brian J. Raney, Bernard Suh, Richard Burhans, Javier Herrero, David Haussler, Rui Faria, Olga Fernando, Fleur Darré, Domènec Farré, Élodie Gazave, Meritxell Oliva, Arcadi Navarro, Roberta Roberto, Oronzo Capozzi, Nicoletta Archidiacono, Giuliano Della Valle, Stefania Purgato, Mariano Rocchi, Miriam K. Konkel, Jerilyn A. Walker, Brygg Ullmer, Mark A. Batzer, Arian F. A. Smit, Robert Hubley, Claudio Casola, Daniel R. Schrider, Matthew W. Hahn, Vı́ctor Quesada, Xosé S. Puente, Gonzalo R. Ordóñez, Carlos López-Otı́n, Tomáš Vinař, Broňa Brejová, Aakrosh Ratan, Robert S. Harris, Webb Miller, Carolin Kosiol, Heather A. Lawson, Vikas Taliwal, André L. Martins, Adam Siepel, Arindam RoyChoudhury, Xin Ma, Jeremiah D. Degenhardt, Carlos D. Bustamante, Ryan N. Gutenkunst, Thomas Mailund, Julien Y. Dutheil, Asger Hobolth, Mikkel Heide Schierup, Oliver A. Ryder, Yuko Yoshinaga, Pieter J. de Jong, George M. Weinstock, Jeffrey Rogers, Elaine R. Mardis, Richard A. Gibbs and 1 more - Nature 2011 cited by 642
- Ancient gene flow from early modern humans into Eastern Neanderthals
Authors: Martin Kuhlwilm, Ilan Gronau, Melissa J. Hubisz, Cesare de Filippo, Javier Prado-Martinez, Martin Kircher, Qiaomei Fu, Hernán A. Burbano, Carles Lalueza‐Fox, Marco de la Rasilla Vives, Antonio Rosas, Pavao Rudan, Dejana Brajković, Željko Kućan, Ivan Gušić, Tomàs Marquès‐Bonet, Aida M. Andrés, Bence Viola, Svante Pääbo, Matthias Meyer, Adam Siepel, Sergi Castellano - Nature 2016 cited by 611
